Search clinical trials for: PF-06751979 single ascending dose

Total 623 results

OX2 Therapeutics

Recruiting

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent High Grade Glioma

United States
Merck KGaA, Darmstadt, Germany

Terminated

Cancer Vaccine Study for Stage III, Unresectable, Non-small Cell Lung Cancer (NSCLC) in the Asian Population (INSPIRE)

Non-Small Cell Lung Cancer

Korea, Republic of, Taiwan, Singapore, China, Hong Kong
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

Study of Tecemotide (L-BLP25) in Participants With Stage III Unresectable Non-small Cell Lung Cancer (NSCLC) Following Primary Chemoradiotherapy

Non-small Cell Lung Cancer

Germany
University of Jordan
Abdelkarim S. Aloweidi

Completed

Does Midazolam Cause Effective Anterograde Amnesia in Orthopedic Surgeries?

Anesthesia | Orthopedic Surgery

Jordan
Parc de Salut Mar

Completed

Study to Detect Oral Administration of Budesonide in Women. (WADA)

Healthy

Spain
Egyptian Liver Hospital
Wadi El Nil Hospital

Completed

Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of Sofosbuvir Tablet Plus Ribavirin Tablet (Part A) Versus Single Dose (2 Tablets) of EHCV Containing Sofosbuvir, Ribavirin, and Natural Anti-hemolytic (B) in Egyptian Adults With Chronic Genotype 4 HCV Infection

Hepatitis c

Egypt
Radboud University Medical Center

Completed

Ticagrelor and Adenosine

Healthy

Netherlands
Fondazione del Piemonte per l'Oncologia

Completed

Study of Efficacy and Safety of Laparoscopic Intra-abdominal Chemotherapy (PIPAC) Performed in Patients With Peritoneal Carcinomatosis From Colorectal, Ovarian, Gastric Cancer and Primary Peritoneal Tumors (PI-CaP)

Peritoneal Carcinomatosis

Italy
AstraZeneca

Completed

Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) (ECLIPSEIII)

Hypertriglyceridemia

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Propranolol HCl 160 mg Tablets Under Non-fasting Conditions

Healthy

United States
Kenneth H. Mayer, MD
Gilead Sciences

Completed

HIV Non-Occupational Post-Exposure Prophylaxis (QUAD)

Human Immunodeficiency Virus

United States
GlaxoSmithKline
Hammersmith Medicines Research; Covance Harrogate

Completed

A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects

Hypertension, Pulmonary

United Kingdom
Ankara Training and Research Hospital

Recruiting

Comparison of the Efficacy and Safety of Continuous and Single-Dose Intravesical Epirubicin Instillation

Bladder Cancer | Superficial Bladder Cancer | Tumor Recurrence | Epirubicin Adverse Reaction

Turkey
Nazmy Edward Seif

Completed

U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy

Analgesia | Surgery | Renal Stone

Egypt
Actavis Inc.

Completed

A Relative Bioavailability Study of Propranolol Hydrochloride 160 mg Tablets Under Fasting Conditions

Healthy

United States
Tampere University
Finnish Cultural Foundation; Sigrid Jusélius Foundation; Päivikki and Sakari... and other collaborators

Recruiting

HaemoDYNAMICs in Primary and Secondary Hypertension (DYNAMIC)

Renal Insufficiency | Aortic Stenosis | Primary Hypertension | Secondary Hypertension

Finland
Leiden University Medical Center

Recruiting

Coadministration of GA2 Sporozoites With Adjuvants (CoGA)

Malaria,Falciparum

Netherlands
Pfizer

Completed

A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignancies

Acute Myeloid Leukemia

Japan
Pfizer

Completed

A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia

United States, Spain, Germany, Italy, Poland, Canada
Cairo University

Unknown

the Efficacy of Giomer Versus Sodium Fluoride in the Treatment of Hypersensitivity

Tooth Hypersensitivity

Egypt
Ulrika Morris
Uppsala University; University of California, San Francisco; RTI International; Mahidol Oxford Tropical Medicine Research Unit and other collaborators

Completed

Effectiveness of Mass Drug Administration for Reducing Seasonal Malaria Transmission in Zanzibar (MaDrAZ)

Malaria | Plasmodium Infections

Tanzania
Actavis Inc.

Completed

Single Dose Two-Way Crossover Fed Bioequivalence Study of Nabumetone 750 mg Tablets in Healthy Volunteers

Healthy

United States
Actavis Inc.

Completed

Single Dose Two-Way Crossover Fasted Bioequivalence Study of Nabumetone 750 mg Tablets in Healthy Volunteers

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of 2 mg Alprazolam OD Tablets Under Non-Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of 2 mg Alprazolam OD Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Amlodipine Besylate 10 mg Tablets Tablets Under Fed Conditions

Healthy

Canada
Actavis Inc.

Completed

A Relative Bioavailability Study of Amlodipine Besylate 10 mg Tablets Under Fasting Conditions

Healthy

Canada
University of Nebraska
Genzyme, a Sanofi Company

Completed

Improved Induction and Maintenance Immunosuppression in Kidney Transplantation

End-stage Renal Disease

United States
Seoul National University Bundang Hospital

Completed

Effect of Vildagliptin in Type 2 Diabetes Treated With Sulphonylurea and Metformin

Diabetes

Korea, Republic of
University of California, Davis

Recruiting

TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant

Pain, Postoperative | Transplant;Failure,Kidney

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of 60 mg Nifedipine Extended Release Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of 50 mg Venlafaxine Hydrochloride Tablets Under Fed Conditions

Healthy

Canada
AstraZeneca

Completed

PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4) (HESTIA4)

Sickle Cell Disease

Belgium, United Kingdom, Italy, Spain, Kenya, Lebanon
Actavis Inc.

Completed

A Relative Bioavailability Study of 60 mg Nifedipine ER Tablets Under Non-fasting Conditions

Healthy

United States
Khon Kaen University

Completed

Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain

a Single-Dose of Etoricoxib | Post-Operative Morphine Consumption | Total Pain Relief Over 8 Hr(TOPAR8) | Post Transabdominal Hysterectomy

Thailand
Memorial Sloan Kettering Cancer Center
Tufts Medical Center; Lahey Clinic

Completed

Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L

Multiple Myeloma

United States
University of Michigan
Food and Drug Administration (FDA)

Completed

Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment

Human Gastrointestinal Physiology Data

United States
Prof. Dr. Jörg Leuppi

Completed

High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study (VitCov)

Covid19 | Vitamin D Deficiency | Corona Virus Infection | ARDS | SARS-CoV Infection | Coronavirus

Switzerland
Ain Shams University

Completed

Doubling the Iron Dose to Prevent IDA in Twin Pregnant Women (IDA)

Hematologic Pregnancy Complications

Egypt
Novartis Pharmaceuticals

Withdrawn

Comparison of Indacaterol With That of Placebo in 'Maintenance naïve' Patients With COPD Using Blinded Tiotropium as Active Control (INITIATE)

Chronic Obstructive Pulmonary Disease (COPD)
BonusBio Group Ltd

Completed

Filling Bone Defects/Voids With Autologous BonoFill For Maxillofacial Bone Regeneration

Bone Void in the Maxillofacial Area

Israel
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Amlodipine/Atorvastatin Combination to Reduce the Health Risk of High Blood Pressure and High Cholesterol Levels (GEMINI-AALA)

Hypertension | Hyperlipidemia

Brazil, Turkey, Taiwan, Argentina, India, Philippines, Singapore, Thailand, Australia, Chile, South Africa, Jordan, Korea, Republic of, Lebanon, United Arab Emirates, Malaysia, Peru, Israel, Indonesia, Guatemala, Hong Kong, Kuwait, ... and more
Actavis Inc.

Completed

A Relative Bioavailability Study of Gabapentin 400 mg Capsules Under Non-fasting Conditions

Healthy

United States
The Hong Kong Polytechnic University
The University of Hong Kong

Not yet recruiting

Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control

Myopia

Hong Kong
German Oncology Center, Cyprus

Active, not recruiting

Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer (Hypo-Combi)

Prostate Adenocarcinoma | Radiation Toxicity

Cyprus
Ifakara Health Institute
University of Oxford

Not yet recruiting

In-vivo Transmission Model in Semi-immune Adults

Controlled Human Malaria Infection | Malaria Transmission | Induced Blood Stage Malaria Infection | Malaria Challenge

Tanzania
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Completed

Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia

Presbyopia

China
Haiphong University of Medicine and Pharmacy

Completed

Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection

Chlamydia Trachomatis Infection | Neisseria Gonorrhoeae Infection

Vietnam
Korea University Anam Hospital

Completed

The Pharmacokinetics, Safety and Tolerability of IN-C009 in Healthy Subjects

Diabetes Mellitus

Korea, Republic of
Albert Koong

Completed

Trilogy Stereotactic Body Radiotherapy for Pancreatic Cancer

Pancreatic Cancer

United States

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