Search clinical trials for: PY159 Single agent dose level 3

Total 848 results

Ikena Oncology
Gilead Sciences

Terminated

A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Gastric Adenocarcinoma | Lung Adenocarcinoma | Advanced Solid Tumor

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in Healthy Male and Pre-menopausal Female Subjects, Including a Comparison of the Effects Under Fasted and Fed Conditions in Healthy Young Male Subjects

Pharmacokinetics of ASP1707 | Pharmacodynamics of ASP1707

France
Basilea Pharmaceutica

Completed

Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally

Fungal Infection

Netherlands
Anagram Therapeutics, Inc.

Recruiting

Phase 1 Study to Assess Safety and Efficacy of ANG003

Exocrine Pancreatic Insufficiency

United States
Autoimmune Technologies, LLC

Completed

Safety Study of Flufirvitide-3 Nasal Spray in Healthy Subjects

Influenza

United States
XOMA (US) LLC

Completed

An Open-Label Study of XOMA 358 in Patients With Hypoglycemia After Gastric Bypass Surgery (XOMA 358)

Hypoglycemia

United States
University of Chicago

Recruiting

Radiation Dose Study for Relapsed/Refractory Hodgkin/Non-Hodgkin Lymphoma

Lymphoma | Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
Ehab L Atallah

Recruiting

XmAb18968 (CD3-CD38) in Relapsed or Refractory Acute Leukemia and T Cell Lymphoblastic Leukemia

Acute Myeloid Leukemia | T Cell Lymphoblastic Lymphoma | T Cell Acute Lymphoblastic Leukemia

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Treating High Risk Leukemia With CD40 Ligand & IL-2 Gene Modified Tumor Vaccine

Leukemia

United States
ThromboGenics

Completed

A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United States
ThromboGenics

Completed

A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United States
Adlai Nortye Biopharma Co., Ltd.

Recruiting

First in Human, Dose Escalation Study of AN4005

Advanced Solid Tumor | Advanced Lymphoma

United States, China
Clementia Pharmaceuticals Inc.

Completed

An Open-Label Extension Study of Palovarotene Treatment in Fibrodysplasia Ossificans Progressiva (FOP)

Fibrodysplasia Ossificans Progressiva

Australia, United States, Argentina, France, United Kingdom
Basilea Pharmaceutica

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

Fungal Infection

Netherlands
Italian Sarcoma Group
Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna

Withdrawn

Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment. (CAST)

Sarcoma

Italy
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Severely Obese Participants With Type 2 Diabetes Mellitus

Obesity and Diabetes Mellitus, Type 2

United States
Shire

Completed

Metazym for the Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)

Metachromatic Leukodystrophy (MLD)

Denmark
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Safety and Tolerability of HTI-1066 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult

United States
Pfizer

Completed

Phase I Study Of The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Multiple Intravenously Administered Doses Of PF-04236921 In Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Spain, Korea, Republic of
Whanin Pharmaceutical Company

Completed

Safety and Efficacy of WIN-901X in Asthma

Asthma

Korea, Republic of
Janssen Research & Development, LLC

Completed

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-55375515 in Healthy Male Participants

Healthy

Netherlands
Scripps Clinic Cancer Center
Threshold Pharmaceuticals

Unknown

TH-302 Plus Doxorubicin Delivered by Trans-Arterial Chemoembolization (TACE) in Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States
GlaxoSmithKline
CureVac

Completed

A Study on the Safety, Reactogenicity and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

Influenza, Human

Belgium, Spain, Canada
Centre Jean Perrin

Recruiting

Targeted Radionuclide Therapy for Metastatic Melanoma [131I] ICF01012 (MELRIV-1)

Melanoma

France
Janssen Research & Development, LLC

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-64991524 in Healthy Participants

Healthy

Belgium
Baylor College of Medicine
University of Texas, Southwestern Medical Center at Dallas

Completed

Evaluating the Use of RFT5-dgA to Deplete Alloreactive Cells Prior to Haploidentical Stem Cell Transplantation

Leukemia | Cancer

United States
Genexine, Inc.

Completed

Safety and Tolerability of GX-P1 in Healthy Male Volunteers

Autoimmune Diseases

Korea, Republic of
AlloVir
Baylor College of Medicine; The Methodist Hospital Research Institute; Center...

Completed

ARMS - Rapidly Generated Multivirus-Specific CTLs for Prophylaxis & Treatment of EBV, CMV, Adenovirus, HHV6 & BK Virus (ARMS)

Viral Infection

United States
Stragen France

Completed

First-In-Human PainCart Study for STR-324

Pain

Netherlands
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects

Myelodysplastic Syndrome (MDS)

China
Longbio Pharma

Recruiting

A Study of Single and Multiple Doses of LP-005 in Healthy Adult Participants

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China
Wellesley Pharmaceuticals, LLC

Completed

Paxerol™ for Treatment of Nocturia - A Phase II Placebo-Controlled Trial

Nocturia

United States
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Doses of LP-003 in Healthy Adult Participants

Chronic Spontaneous Urticaria

China
Rockefeller University
Brigham and Women's Hospital; Weill Medical College of Cornell University; University...

Completed

A Phase 1, Open Label, Dose-escalation Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 3BNC117

Healthy | HIV

United States, Germany
Emory University
Georgia Center for Oncology Research & Education

Not yet recruiting

Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV

Human Immunodeficiency Virus | Human Papilloma Virus | Anal Intraepithelial Neoplasia | High-Grade Squamous Intraepithelial Lesions

United States
Genentech, Inc.

Completed

A Study of Crenezumab in Participants With Mild to Moderate Alzheimer Disease

Alzheimer Disease

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Active, not recruiting

A Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label, Long-Term Safety Phase to Evaluate the Efficacy and Safety of TV-44749 in Adults With Schizophrenia (SOLARIS)

Schizophrenia

United States, Bulgaria, China, Romania, Turkey
Consorzio per Valutazioni Biologiche e Farmacologiche
European Commission

Completed

Pharmacokinetic Study of Deferiprone in Paediatric Patients (DEEP-1)

Chronic Iron Overload

Italy, Cyprus, Egypt
Wang Min
Lanyue Biotech (Hangzhou) Co., Ltd.

Recruiting

A Clinical Study Evaluating the Safety, Tolerability and Initial Efficacy of SKG0106 Intravitreal Injection in Diabetic Macular Edema (DME) Patients

Diabetic Macular Edema

China
Children's Hospital Los Angeles
Lucile Packard Children's Hospital

Terminated

Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells

Metabolic Diseases | Stem Cell Transplantation | Chronic Granulomatous Disease | Bone Marrow Transplantation | Thalassemia | Wiskott-Aldrich Syndrome | Genetic Diseases | Peripheral Blood Stem Cell Transplantation | Pediatrics | Diamond-Blackfan Anemia | Allogeneic Transplantation | Combined Immune Deficiency | X-linked Lymphoproliferative Disease
Jichi Medical University
Takara Bio Inc.

Unknown

Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes

Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Japan
Sir Run Run Shaw Hospital

Recruiting

Molecular Basis of Loss Aversion

Healthy

China
RayzeBio, Inc.

Recruiting

Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC

SCLC,Extensive Stage

United States, Puerto Rico
GlaxoSmithKline

Completed

Primary Vaccination With Either Synflorix™ or Prevenar 13™ or Both Vaccines and Booster Vaccination With Synflorix™

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Mexico
Nebraska Methodist Health System

Active, not recruiting

De-Escalation Protocol Of HPV Mediated Oropharyngeal Squamous Cell Carcinoma

Oropharynx Cancer | HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage

United States
Per Pfeiffer

Completed

Chemotherapy for Patients With Cancer of the Stomach (DOS)

First-line Treatment for Patients With Non-resectable Gastric Cancer or Cancer of the Esophagus or

Denmark
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Non-diabetic Severely Obese Participants

Obesity

United States, Belgium, United Kingdom, Sweden, Poland, Canada
Rockefeller University
University of Cologne

Completed

A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074

Healthy | HIV

Germany, United States
GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
Boehringer Ingelheim

Completed

Single Dose Ranging Study of BI 1744 CL (Olodaterol) in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Netherlands

Search clinical trials for: PY159 Single agent dose level 3

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