Search clinical trials for: Pemetrexed Disodium

Total 10700 results

UNICANCER
National Cancer Institute, France

Recruiting

PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer (NIRVANA-LUNG)

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Metastatic | Non-Small Cell Carcinoma of Lung, TNM Stage 4

France, Monaco
Genentech, Inc.

Completed

A Study of the Safety and Pharmacology Of PI3-Kinase Inhibitor GDC-0941 In Combination With Either Paclitaxel And Carboplatin (With or Without Bevacizumab) or Pemetrexed, Cisplatin, And Bevacizumab in Patients With Advanced Non-Small Cell Lung Cancer

Non-Squamous Non-Small Cell Lung Cancer

United States, France, Netherlands
Gruppo Oncologico Italia Meridionale

Unknown

Quality of Life Comparison in Advanced Non-squamous Non Small Cell Lung Cancer (ERACLE)

Non-squamous Nonsmall Cell Neoplasm of Lung

Italy
Advaxis, Inc.

Withdrawn

A Study of Pemetrexed Maintenance With or Without ADXS11-001 Immunotherapy in Patients With Human Papillomavirus Positive (HPV+), NSCLC Following First-Line Induction Chemotherapy

Carcinoma, Non-Small-Cell Lung
Sumitomo Pharma Co., Ltd.

Completed

A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma

Non-Small Cell Lung Cancer | Malignant Pleural Mesothelioma

Japan
University Health Network, Toronto
Eli Lilly and Company

Terminated

Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesothelioma

Mesothelioma | Pleural Mesothelioma

Canada
Hoosier Cancer Research Network
Eli Lilly and Company

Terminated

Pemetrexed and Radiation for Poor-Risk Stage III Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
Washington University School of Medicine
Eli Lilly and Company

Terminated

A Phase II Study of Pemetrexed and Carboplatin in the Treatment of Esophageal Cancer

Esophageal Neoplasms

United States
Boehringer Ingelheim

Completed

Dose Escalation Study of BI 2536 With Pemetrexed in Previously Treated Patients With Non-small-cell Lung Cancer

Carcinoma, Non-Small-Cell Lung
Fudan University

Completed

Pemetrexed and Platinum Use in the Neoadjuvant Setting for Resectable Stage II and IIIA Lung Adenocarcinoma (ECTOP-1002)

Lung Adenocarcinoma

China
Chonnam National University Hospital
Pusan National University Hospital; Korea University Guro Hospital; Kyungpook... and other collaborators

Completed

Efficacy and Safety of Adjuvant Pemetrexed Plus Cisplatin for Adenocarcinoma of Lung (APICAL)

Adenocarcinoma | Lung Neoplasm

Korea, Republic of
Fudan University

Unknown

Almonertinib/Pemetrexed/Carboplatin in EGFR T790M+ Advanced Lung Cancer (APPEAL)

Lung Cancer, Non-small Cell | EGFR Gene Mutation | EGFR T790M

China
OncoMed Pharmaceuticals, Inc.
Celgene Corporation

Completed

A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer (DENALI)

Nonsquamous Nonsmall Cell Neoplasm of Lung

Spain, United States, Australia, Italy, Belgium
Samsung Medical Center

Unknown

A Study Comparing Pemetrexed Plus Cisplatin Versus Pemetrexed Alone in NSCLC Patients Who Have Progressed on First Line EGFR-TKI

Carcinoma, Non-Small-Cell Lung

Korea, Republic of
Wuhan Union Hospital, China

Not yet recruiting

Diagnosis of Leptomeningeal Metastasis and the Monitoring of Intrathecal Chemotherapy Efficacy in NSCLC

Diagnosis

China
Nagla Abdel Karim

Completed

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Carcinoma, Non-Small-Cell Lung | Ovarian Cancer | Thymoma | Mesothelioma | Bladder Cancer | Peritoneal Cancer | Thymus Cancer | Uterine Cervical Cancer

United States
Ohio State University Comprehensive Cancer Center

Completed

Pemetrexed Chemotherapy in Poor-Risk Patients With Advanced Head and Neck Cancer

Head and Neck Cancer

United States
University of Florida

Withdrawn

Study of Pemetrexed to Treat Recurrent or Progressive Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma
Eli Lilly and Company

Completed

Performance Status During Treatment With Pemetrexed in Patients With NSCLC (PERFORMANCE)

Non Small Cell Lung Cancer

Germany
Eli Lilly and Company

Completed

Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesothelioma

Malignant Pleural Mesotherioma

Japan
Chiesi Farmaceutici S.p.A.

Completed

Efficacy Of Clodronate 200 Mg/4 Ml I.M. Solution With 1% Lidocaine Every Other Week Vs Clodronate 100 Mg/3,3ml I.M. Solution With 1% Lidocaine Once-Week In A 1-Year Treatment Period Of Women With Postmenopausal Osteoporosis

Postmenopausal Osteoporosis

Italy
National Cancer Institute (NCI)

Completed

A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...

Carcinoma, Renal Cell | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pheochromocytoma

United States
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Study of Chemotherapy and PD-1 Inhibitor Combination With Autologous CIK Cell Immunotherapy to Treat Lung Cancer (CCICC-002b)

Non-small Cell Lung Cancer Metastatic | First-line Treatment

China
Bristol-Myers Squibb

Completed

Nivolumab in Combination With Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer (CheckMate 568)

Non-Small-Cell Lung Cancer

United States, Canada
The First Hospital of Jilin University

Unknown

Apatinib Combined With Chemotherapy for NSCLC Patients Without T790M Mutation

Non Small Cell Lung Cancer

China
Cancer Institute and Hospital, Chinese Academy...

Unknown

Low -Dose-bevacizumab and Pemetrexed Versus TPC in Metastatic HER2-negative Breast Cancer Patients

Metastatic Breast Cancer

China
Aduro Biotech, Inc.

Completed

Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma

United States
Boehringer Ingelheim

Completed

BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid Tumours

Neoplasms

Canada
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
AbbVie

Completed

An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Canada, Puerto Rico
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

Mesothelioma | Mesothelioma, Malignant | Malignant Mesothelioma | Peritoneal Mesothelioma | Malignant Peritoneal Mesothelioma

United States
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC

Carcinoma, Non-Small-Cell Lung | Leptomeningeal Metastasis | Epidermal Growth Factor Receptor
Sun Yat-sen University
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Camrelizumab With AC in Patients With Brain Metastases of Driven Gene-negative,NSCLC (CAP-BRAIN)

Brain Metastases | Non-squamous Non-small-cell Lung Cancer

China
Cancer Institute and Hospital, Chinese Academy...
Jiangsu Hansoh Pharmaceutical Co., Ltd.; GeneCast Biotechnology Co., Ltd.

Enrolling by invitation

Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour Resection (APEX)

Non-small Cell Lung Carcinoma

China
Centre Georges Francois Leclerc

Completed

Pemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies (PKAPIR)

Non-small Cell Lung Cancer

France
Morphotek

Completed

An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesothelioma (Amatuximab)

Malignant Pleural Mesothelioma

United States, Canada, Germany, Spain, Netherlands
Bayer

Completed

Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors

Medical Oncology

United States, Italy
Association of Paediatric and Preventive Dentists...

Completed

Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Teeth

Periapical Diseases
AstraZeneca

Completed

ZD4054 (Zibotentan) Phase II Non-Small Cell Lung Cancer Study

Lung Cancer | Non Small Cell Lung Cancer

Bulgaria, Romania, Ukraine, France, Czech Republic
Wuhan Union Hospital, China

Not yet recruiting

Monitoring the Efficacy of Duvalizumab Combined With Neoadjuvant Chemotherapy for Ib-IIIb NSCLC by Sequencing of Immune Receptor Repertoire: a Prospective, One Arm Clinical Study

Ib-IIIb NSCLC
NanoAlvand

Completed

Alvopem® (Pemetrexed) Safety Assessment

Non Small Cell Lung Cancer | Malignant Pleural Mesothelioma
Eli Lilly and Company

Completed

A Study in Non Small Cell Lung Cancer

Non Small Cell Lung Cancer

Spain, Germany
Eli Lilly and Company

Completed

An Observational Study of the Ethnic Impact of Patients Undergoing Second (2nd) Line Treatment for Non-Small Cell Lung Cancer Using Pemetrexed

Lung Neoplasms

United States, Puerto Rico
Eli Lilly and Company

Completed

Chemotherapy for Patients With Osteosarcoma

Osteosarcoma

Germany, Spain, France, Italy, United Kingdom
Eli Lilly and Company

Completed

Pemetrexed and Carboplatin in Locally Advanced or Metastatic Breast Cancer

Breast Cancer | Neoplasm Metastasis

Russian Federation
Sichuan Baili Pharmaceutical Co., Ltd.

Recruiting

SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC.

Non Small Cell Lung Cancer

China
Fifth Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Neoadjuvant Afatinib Combination With Chemotherapy for Stage Ⅱa-Ⅲb NSCLC With EGFR Activating Mutation (Neoafa)

Chemotherapy | Surgery | Non Small Cell Lung Cancer | EGFR Activating Mutation | EGFR TKI
Rachel Sanborn
AstraZeneca; Providence Cancer Center, Earle A. Chiles Research Institute

Active, not recruiting

Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer

Lung Cancer | Non-small Cell Carcinoma

United States
AbbVie

Completed

Study of Veliparib in Combination With Nivolumab and Platinum Doublet Chemotherapy in Participants With Metastatic or Advanced Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer

United States
Shanghai University of Traditional Chinese Medicine
Shanghai Chest Hospital; Shanghai Pulmonary Hospital, Shanghai, China

Completed

Clinical Study of Chinese Medicine Plus Chemotherapy Maintenance in Advanced Non Small Cell Lung Cancer

Cancer

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