Search clinical trials for: Personalized Synthetic Long Peptide Vaccine

Total 740 results

Jaime Leandro Foundation for Therapeutic Cancer...

Enrolling by invitation

Basket Trial of Neoantigen Synthetic Long Peptide Vaccines in Patients With Advanced Malignancy

Cancer | Solid Tumor

United States
African Malaria Network Trust
London School of Hygiene and Tropical Medicine

Unknown

A Phase Ib Trial of MSP 3 LSP in 1-2 Year Old Children in Burkina Faso (MSP3LSP)

Malaria

Burkina Faso
African Malaria Network Trust
London School of Hygiene and Tropical Medicine

Unknown

Phase Ib Trial of MSP3 LSP in Children in Tanzania (MSP3TN)

Malaria

Tanzania
National Liver Institute, Egypt

Unknown

Safety and Efficacy Study of CENV3 Vaccine to Protect Against HCV Infection (CENV3)

Vaccine Overdose of Undetermined Intent

Egypt
African Malaria Network Trust

Unknown

Immunogenicity, Efficacy and Safety Study of an MSP3-LSP (Long Synthetic Peptide) Malaria Vaccine

Malaria

Mali
ISA Pharmaceuticals
Dutch Cancer Society

Completed

Study of the Therapeutic Vaccine (ISA101/ISA101b) to Treat Advanced or Recurrent Cervical Cancer (CervISA)

Cervical Cancer

Germany, Netherlands, Belgium
Nina Bhardwaj

Completed

Safety and Immunogenicity of Personalized Genomic Vaccine to Treat Malignancies

Solid Tumors

United States
Washington University School of Medicine
Susan G. Komen Breast Cancer Foundation

Withdrawn

Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Triple-Negative Breast Cancer
Gitte Kronborg
Rigshospitalet, Denmark; Hvidovre University Hospital; Statens Serum Institut; Ministry...

Completed

Immunization With HIV-1 Peptides in Adjuvant for Treatment of Patients With Chronic HIV-infection (HIV-VAC)

HIV INFECTIONS

Denmark
Centre Hospitalier Universitaire Vaudois

Recruiting

Personalized Vaccine With SOC Chemo Followed by Nivo in Pancreatic Cancer

Pancreatic Adenocarcinoma

Switzerland
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Hodgkin Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myelodysplastic/Myeloproliferative Neoplasm | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Cytomegalovirus... and other conditions

United States
National Cancer Institute (NCI)

Completed

Booster Vaccination in Preventing Disease Recurrence in Previously Vaccinated Patients With Melanoma That Has Been Removed By Surgery

Stage IV Skin Melanoma | Recurrent Melanoma | Stage IIIB Skin Melanoma | Stage IIIC Skin Melanoma | Stage IIA Skin Melanoma | Stage IIB Skin Melanoma | Stage IIC Skin Melanoma | Stage IIIA Skin Melanoma | Stage IA Skin Melanoma | Stage IB Skin Melanoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant

Hematopoietic Cell Transplant Recipient | Cytomegaloviral Infection

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Sargramostim in Treating Patients With Non-small Cell Lung Cancer

Lung Cancer

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab

Stage IV Breast Cancer | HER2/Neu Positive | HLA-A2 Positive Cells Present | Stage IV Ovarian Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Preventing Cytomegalovirus in Healthy Participants

Nonneoplastic Condition

United States
Swiss Tropical & Public Health Institute

Terminated

Phase Ia Malaria Vaccine Trial of Two Virosome-Formulated Peptides

Falciparum Malaria
YueJuan Cheng
NeoCura

Recruiting

Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Solid Tumors

Solid Tumor

China
The University of Hong Kong-Shenzhen Hospital

Not yet recruiting

iTAPVR Study - Phase II Randomized Study

Advanced Tumors
United Biomedical

Completed

A Phase I/II Safety and Immunogenicity Trial of UBI Microparticulate Monovalent (HIV-1 MN) Branched Peptide Vaccine in HIV-1 Seronegative Human Subjects

HIV Infections

United States
M.D. Anderson Cancer Center
The Vaccine Company

Terminated

PR1 Vaccination in Myelodysplastic Syndrome (MDS)

Leukemia | Myelodysplastic Syndrome

United States
Washington University School of Medicine
National Cancer Institute (NCI); Leidos; UNICO Foundation

Active, not recruiting

Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Guangdong 999 Brain Hospital
Jinan University Guangzhou; Beijing Tricision Biotherapeutics Inc; Trinomab Biotech...

Completed

Personalized Cellular Vaccine for Glioblastoma (PERCELLVAC) (PERCELLVAC)

Glioblastoma

China
University of Maryland Greenebaum Cancer Center
National Cancer Institute (NCI)

Completed

Stem Cell Transplant, Chemotherapy, and Biological Therapy in Treating Patients With High-Risk or Refractory Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma

Melanoma (Skin)

United States
COL George Peoples, MD, FACS

Completed

Phase I/IIa Trial of Folate Binding Protein Vaccine in Ovarian Cancer

Ovarian Cancer | Endometrial Cancer | Peritoneal Cancer | Fallopian Cancer

United States
Guangdong 999 Brain Hospital
Jinan University Guangzhou; Beijing Tricision Biotherapeutics Inc; Trinomab Biotech...

Completed

Personalized Cellular Vaccine for Recurrent Glioblastoma (PERCELLVAC2) (PerCellVac2)

Glioblastoma

China
Michael Morse, MD
Immunotope

Completed

A Phase I Study of Ovarian Cancer Peptides Plus GM-CSF and Adjuvant With Ovarian, Tubal or Peritoneal Cancer

Epithelial Ovarian, Tubal or Peritoneal Cancer

United States
Hospital Universitario Reina Sofia de Cordoba
Instituto de Salud Carlos III

Completed

Tobacco Intensive Motivational and Estimate Risk

Smoking Cessation | COPD | Severe Mental Disorder

Spain
University of California, Davis
National Cancer Institute (NCI); IO Biotech

Recruiting

IDO and PD-L1 Peptide Based Immune-Modulatory Therapeutic (IO102-IO103) in Combination With Pembrolizumab for BCG-Unresponsive or Intolerant, Non-Muscle Invasive Bladder Cancer

Stage 0a Bladder Cancer AJCC v8 | Stage 0is Bladder Cancer AJCC v8 | Stage I Bladder Cancer AJCC v8 | High Risk Non-Muscle Invasive Bladder Urothelial Carcinoma

United States
City of Hope Medical Center
National Cancer Institute (NCI); Diavax Biosciences

Active, not recruiting

Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant

Hodgkin Lymphoma | Myelofibrosis | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Lymphadenopathy | Myeloproliferative Neoplasm | Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Acute Myeloid Leukemia in Remission | Accelerated Phase... and other conditions

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy

Myelodysplastic Syndrome | Acute Myeloid Leukemia (AML) | Chronic Myeloid Leukemia (CML)

United States
University Hospital Tuebingen

Not yet recruiting

Multi-peptide Vaccination Adjuvanted With XS15 in Acute Myeloid Leukemia Patients (AML-VAC-XS15)

Acute Myeloid Leukemia, Adult
Chinese PLA General Hospital
Likang Life Sciences Holdings Limited

Unknown

A Study Combining Personalized Neoantigen-based Dendritic Cell Vaccine With Microwave Ablation for the Treatment of Hepatocellular Carcinoma

Hepatocellular Carcinoma | Liver Cancer, Adult

China
Xuanwu Hospital, Beijing
Beijing Neoantigen Biotechnology Company

Recruiting

Personalized Vaccine for Patients With Recurrent Malignant Glioma

Malignant Glioma | Recurrent Glioma

China
COL George Peoples, MD, FACS
M.D. Anderson Cancer Center

Completed

Phase Ib Trial of Two Folate Binding Protein Peptide Vaccines (E39 and J65) in Breast and Ovarian Cancer Patients (J65)

Breast Cancer | Ovarian Cancer

United States
Guangdong 999 Brain Hospital
Jinan University Guangzhou; Beijing Tricision Biotherapeutics Inc; Trinomab Biotech...

Completed

Personalized Cellular Vaccine for Brain Metastases (PERCELLVAC3) (PerCellVac3)

Brain Cancer | Neoplasm Metastases

China
Anda Biopharmaceutical Development (Shenzhen) Co...

Recruiting

Clinical Trial on Personalized Neoantigen Vaccine for Pancreatic Tumor

Pancreatic Tumor

China
Inge Marie Svane

Completed

Dual Vaccine Trial in Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia

Denmark
Beijing Tiantan Hospital
ZhongSheng BioTech Inc.

Recruiting

Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas

WHO Grade III Gliomas | WHO Grade IV Gliomas

China
University of Virginia
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Melanoma

Melanoma (Skin)

United States
University Hospital Tuebingen

Available

Personalized Multi-peptide Vaccination in Combination With the TLR1/2 Ligand XS15 in Cancer Patients (InHeVac01)

Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns...

Recruiting

Prophylactic Peptide Vaccine in Advanced ALK+ NSCLC

NSCLC Stage IV | ALK Fusion Protein Expression

United States
Centre Hospitalier Universitaire Vaudois

Recruiting

Personalized DC Vaccines in Non Small Cell Lung Cancer

Non-small Cell Lung Cancer

Switzerland
Changhai Hospital
Stemirna Therapeutics

Unknown

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Digestive System Neoplasms

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Colorectal Adenocarcinoma | Advanced Esophageal Squamous Carcinoma

China
Stemirna Therapeutics
The First Affiliated Hospital of Zhengzhou University

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Esophageal Cancer and Non-small Cell Lung Cancer

Esophageal Cancer | Non Small Cell Lung Cancer

China
Washington University School of Medicine
Susan G. Komen Breast Cancer Foundation

Completed

Safety and Immunogenicity of a Personalized Polyepitope DNA Vaccine Strategy in Breast Cancer Patients With Persistent Triple-Negative Disease Following Neoadjuvant Chemotherapy

Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Triple-Negative Breast Cancer

United States
Inge Marie Svane

Recruiting

Combination Therapy With Nivolumab and PD-L1/IDO Peptide Vaccine to Patients With Metastatic Melanoma

Metastatic Melanoma

Denmark
H. Lee Moffitt Cancer Center and Research Institute
National Institutes of Health (NIH)

Completed

PSMA and TARP Peptide Vaccine With Poly IC-LC Adjuvant in HLA-A2 (+) Patients With Elevated PSA After Initial Definitive Treatment

Prostate Cancer

United States, Puerto Rico
University Hospital Tuebingen
Cooperative Weichteilsarkom Study Group; Deutsches Konsortium fürTranslationale... and other collaborators

Recruiting

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision) (PerVision)

Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma

Germany

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