Search clinical trials for: Pirfenidone placebo

Total 53981 results

Nowarta Biopharma Inc

Completed

A Phase I/II Double-blind Safety and Efficacy Evaluation of Nowarta110 in Patients With Plantar Warts

Plantar Warts

United States
Hoffmann-La Roche

Completed

Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary Hypertension

Idiopathic Pulmonary Fibrosis

Hungary, Belgium, Germany, Netherlands, Italy, Israel, Spain, Canada, South Africa, Turkey, Czechia, Egypt, Greece
Soroka University Medical Center
Roche Pharma AG

Completed

Treatment With Pirfenidone for COVID-19 Related Severe ARDS

Covid19 | ARDS

Israel
Chinese University of Hong Kong

Recruiting

RCT for Yinqiaosan-Maxingganshitang in the Treatment of COVID-19

COVID-19

Hong Kong
National University of Malaysia
Malaysia Palm Oil Board

Unknown

Supplementation of Oil Palm Phenolics to Healthy Participants (SPIRAL)

Cardiovascular Diseases | Hypercholesterolemia | Hyperlipidemias

Malaysia
University of Guadalajara
Cell Therapy And Technology, S.a. De C.v.

Completed

Utility of Prolonged-release Pirfenidone in the Progression of Chronic Kidney Disease

Fibrosis | Chronic Kidney Disease
University of South Carolina
U.S. Army Medical Research and Development Command

Completed

Dietary Seaweed and Early Breast Cancer: A Randomized Trial

Seaweed Associated Changes in Healthy Subjects

United States
Gladwin, Mark, MD
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age (Nitrite)

Sedentary Lifestyle | Frailty | Aging

United States
Mersin University

Completed

The Effect of Post-Cesarean Section Acupressure on the Severity of Pain and First Mobilization Distance (Acupress)

Pain | Mobilization

Turkey
John Paul II Hospital, Krakow
National Center for Research and Development, Poland; KCRI

Active, not recruiting

Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With No-option Critical Limb Ischemia (N-O CLI)

Critical Limb Ischemia

Poland
John Paul II Hospital, Krakow
National Center for Research and Development, Poland; KCRI

Completed

Randomized Clinical Trial to Evaluate the Regenerative Capacity of CardioCell in Patients With Chronic Ischaemic Heart Failure (CIHF)

Heart Failure

Poland
Hoffmann-La Roche

Completed

A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom, Belgium, Germany, France, Sweden, Austria, Denmark, Italy
Excalibur Pharmaceuticals, Inc.

Completed

Randomized, Crossover, Multi-Dose Pharmacokinetics of EXCL-100 Pirfenidone-Sustained Release Tablet and Esbriet in Healthy Volunteers

Idiopathic Pulmonary Fibrosis

United States
Postgraduate Institute of Medical Education and...

Active, not recruiting

Pirfenidone vs. Nintedanib for Fibrotic Lung Disease After Coronavirus Disease-19 Pneumonia (PINCER)

Novel Coronavirus-induced Lung Fibrosis

India
Galapagos NV

Completed

Drug-drug Interaction Study With GLPG4716 and Nintedanib and Pirfenidone in Healthy Subjects

Healthy

Germany
Daewoong Pharmaceutical Co. LTD.

Completed

To Evaluate Drug-drug Interactions Between DWN12088 and Pirfenidone or Nintedanib in Healthy Volunteers

Idiopathic Pulmonary Fibrosis

Korea, Republic of
Boehringer Ingelheim

Completed

Dose Reduction and Discontinuation With Anti-Fibrotic Medications

Idiopathic Pulmonary Fibrosis

United States
Resverlogix Corp

Not yet recruiting

A Two-Part Phase 2a Study of RVX000222 in Patients With End-Stage Renal Disease Treated With Hemodialysis

Kidney Failure, Chronic
Fengmei Lian
Guang'anmen Hospital of China Academy of Chinese Medical Sciences; Hubei Hospital... and other collaborators

Unknown

Clinical Study of Tang Wang Prescription Intervene Diabetic Non-proliferative Retinopathy

Type2 Diabetes | Diabetic Non-proliferative Retinopathy
LEO Pharma

Completed

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

Atopic Dermatitis

United States, Belgium, Canada, Australia, France, Germany, Japan, Netherlands, Poland, United Kingdom
Guang'anmen Hospital of China Academy of Chinese...
Hubei Hospital of Traditional Chinese Medicine; Hebei Yiling Hospital; The First... and other collaborators

Unknown

The Multi-Centric Clinical Study of Chinese Medicine Intervention on Diabetes Distal Symmetric Polyneuropathy.

Type 2 Diabetes Mellitus
John Paul II Hospital, Krakow
National Center for Research and Development, Poland; KCRI

Completed

Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With Acute Myocardial Infarction (AMI)

Myocardial Infarction

Poland
Hoffmann-La Roche

Completed

Safety and Tolerability Study of Pirfenidone in Combination With Nintedanib in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States, Canada, Denmark, France, Germany, Italy, Netherlands, Spain
Boehringer Ingelheim

Completed

A Study Based on Medical Records That Looks at the Characteristics of Idiopathic Pulmonary Fibrosis Patients Grouped by the Type of Medication They Are Taking

Idiopathic Pulmonary Fibrosis

United States
University of Kansas Medical Center
parkview cancer institute

Recruiting

Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC

NSCLC Stage IV | NSCLC, Recurrent

United States
Sunshine Lake Pharma Co., Ltd.

Completed

To Evaluate Drug-drug Interactions Between HEC585 and Pirfenidone or Nintedanib in Healthy Volunteers

Idiopathic Pulmonary Fibrosis

China
Shengjing Hospital

Completed

Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation

Constipation | Chinese Herbal Medicine

China
AstraZeneca

Completed

A Study of AZD8233 in Participants With Dyslipidemia. (HAYATE)

Dyslipidemia

Japan
Albert Einstein College of Medicine

Completed

Sodium Bicarbonate Supplementation in Chronic Kidney Disease Evaluation of Dose Response, Safety and Beneficial Effects

Chronic Kidney Disease

United States
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test Whether BI 1015550 Influences the Amount of Nintedanib and Pirfenidone in the Blood

Healthy

Germany
Qilu Hospital of Shandong University

Recruiting

Efficacy and Safety of Pirfenidone in CTD-ILD

Connective Tissue Diseases | Interstitial Lung Disease | Pirfenidone

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Greater Washington Community Foundation

Terminated

Muscadine Plus (MPX) In Men With Prostate Cancer

Adenocarcinoma of the Prostate

United States
Novartis Pharmaceuticals

Completed

A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ORION-5)

Homozygous Familial Hypercholesterolemia

Hong Kong, Israel, Russian Federation, Serbia, South Africa, Taiwan, Turkey, Ukraine
Contera Pharma
Bukwang Pharmaceutical

Completed

A Study in Parkinson's Disease in Patients With Moderate to Severe Dyskinesia (ASTORIA)

Dyskinesias

France, Germany, Italy, Korea, Republic of, Spain
University of California, San Diego

Terminated

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC (ILEUS)

Ileus

United States
Novartis

Completed

Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects With Acute Blunt Trauma Injuries

Acute Blunt Soft Tissue Injuries/Contusions

United States
Fengmei Lian
Peking Union Medical College Hospital; Huashan Hospital; Chengdu University of... and other collaborators

Unknown

Post-marketing Evaluation of Mudan Granule Intervention on Type 2 Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy Type 2

China
William Beaumont Hospitals

Terminated

Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis (PRONE)

Fibrosis, Liver | Cirrhosis, Liver | Steatohepatitis, Nonalcoholic | Fatty Liver Disease

United States
Vanderbilt University
Merck Sharp & Dohme LLC

Withdrawn

Vorapaxar and Lower Extremity Bypass Grafts

Peripheral Artery Disease
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in COPD Cachexia

Cachexia | COPD

Sweden
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in NSCLC Cachexia

NSCLC | Cachexia

Italy, Sweden, Croatia, Slovakia
Kuopio University Hospital

Withdrawn

Post-operative Corticosteroid Treatment After Mitral Valve Surgery (MitralPOCS)

Atrial Fibrillation

Finland
ISU Abxis Co., Ltd.

Unknown

Exploratory P2 Trial to Evaluate Efficacy and Safety of Clotinab® (Abciximab) in Acute MI Patients

Acute Myocardial Infarction

Korea, Republic of
Xijing Hospital of Digestive Diseases

Completed

Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies

Gastric Cancer | Helicobacter Pylori Infection | Bismuth

China
Gateway Institute for Brain Research

Recruiting

Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease (NOSE-PD)

Parkinson Disease

United States
University of Aarhus

Completed

Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT

Primary Biliary Cirrhosis

Denmark
Chinese PLA General Hospital

Unknown

Cell Therapy in Patients With Chronic Ischemic Heart Disease Undergoing Cardiac Surgery

Left Ventricular Dysfunction | Chronic Myocardial Ischemia | Old Myocardial Infarction

China
Sinocelltech Ltd.

Unknown

SCT-I10A Plus Standard Chemotherapy in First-line Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

China
NextCell Pharma Ab

Completed

Wharton´s Jelly Derived Mesenchymal Stromal Cell Treatment of Adult Patients Diagnosed With Type I Diabetes

Type1 Diabetes Mellitus

Sweden
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Chest... and other collaborators

Not yet recruiting

Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Lung Cancer

China

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