Search clinical trials for: Placebo to ibuprofen

Total 60734 results

Yi Feng, MD

Unknown

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Ibuprofen 400 and 800 mg Every 6 Hours in the Management of Postoperative Pain.

Pain | Ibuprofen | Nonsteroidal Anti-inflammatory Drug | Intravenous | Injectable | Analgesic

China
Merck Sharp & Dohme LLC

Completed

Tolerability and Efficacy of Ibuprofen 800 mg in a Walking Model of Osteoarthritis Pain (0000-057)

Osteoarthritis, Knee
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Ibuprofen in Healthy Volunteers

Healthy Volunteer

United States
Reckitt Benckiser Healthcare (UK) Limited
Simbec Research

Completed

Ibuprofen Bioavailability Study

Healthy

United Kingdom
Gilead Sciences
Galapagos NV

Terminated

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Psoriatic Arthritis Who Are Naive to Biologic DMARD Therapy (PENGUIN 1)

Psoriatic Arthritis

Korea, Republic of, United States, Taiwan, Australia, Canada, Japan, Poland, Spain, New Zealand, Czechia, Hungary, Bulgaria, Russian Federation
Noema Pharma AG

Completed

A 10-week Efficacy Study of NOE-105 in Childhood Onset Fluency Disorder (Orpheus)

Childhood-Onset Fluency Disorder

United States, Australia
Jean Brown Research

Completed

Ibuprofen Versus Placebo For Muscle Soreness

Muscle Soreness

United States
University of Minnesota

Withdrawn

Local Anesthesia and Analgesics in Endodontic Pain (LAAEP)

Odontalgia

United States
Apsen Farmaceutica S.A.

Completed

Efficacy and Safety of S (+) - Ibuprofen in Osteoarthritis Pain (APS003/2020)

Osteoarthritis

Brazil
Lawson Health Research Institute

Completed

Regular vs Intermittent Dose Ibuprofen for the Treatment of Ankle Sprains in Children

Ankle Injuries | Ibuprofen

Canada
Boehringer Ingelheim

Completed

Study to Assess the Kinetic of the Analgesic Effect and Tolerability of Eschscholtzia Californica Versus Ibuprofen and Placebo in the Treatment of Pain After Surgery of the Third Molar

Pain
University of Nebraska
University of California, Los Angeles; University of Alabama at Birmingham; Temple... and other collaborators

Completed

Prostaglandin Inhibition for Emphysema (PIE)

Emphysema

United States
Pfizer

Completed

A Safety And Efficacy Study of Ibuprofen 250 mg / Acetaminophen 500 mg In The Treatment Of Post-Surgical Dental Pain (SDDP)

Post-surgical Pain Following Extraction of Molar Teeth

United States
Boehringer Ingelheim

Completed

Study to Compare the the Analgesic Efficacy and Tolerability of Meloxicam Versus Placebo and Ibuprofen in the Treatment of Pain After Surgery of the Third Molar

Pain
Kissei Pharmaceutical Co., Ltd.

Completed

Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain (EDELWEISS 6)

Endometriosis

United States, Austria, Bulgaria, Czechia, France, Poland, Romania, Spain, Ukraine
Kissei Pharmaceutical Co., Ltd.

Terminated

Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain (EDELWEISS 5)

Endometriosis

United States, Canada, Puerto Rico
Laureate Institute for Brain Research, Inc.

Recruiting

Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression

Bipolar Depression

United States
Inonu University

Completed

Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Therapy (ECT)

Myalgia | Postoperative Pain | Headache

Turkey
ObsEva SA

Terminated

A Phase 3 Study to Confirm the Efficacy and Safety of Linzagolix to Treat Endometriosis-associated Pain

Endometriosis

United States, Canada, Puerto Rico
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sympatholysis in Chronic Kidney Disease (Sym-CKD)

Chronic Kidney Disease

United States
Merck Sharp & Dohme LLC

Completed

Three-Dose Regimen of MRKAd5+6 Trigene (V526) in Healthy Adults (V526-001)(COMPLETED)

HIV Infections | HIV
Kissei Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain.

Endometriosis

United States, Austria, Bulgaria, Czechia, France, Poland, Romania, Spain, Ukraine, Hungary
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis

Cystic Fibrosis

Netherlands, United Kingdom
Novartis Pharmaceuticals

Completed

Safety and Efficacy of DNK333 in Atopic Dermatitis Patients

Pruritus in Patients With Atopic Dermatitis

Germany
Pierre Fabre Medicament

Completed

Ibuprofen Lozenge in Acute Sore Throat Pain

Acute Sore Throat Pain

United Kingdom, Germany, Latvia, France
AstraZeneca

Completed

Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD

Poland, United Kingdom, Germany, Sweden, Denmark
Bayer

Terminated

A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT) (REMOTE-HF)

Chronic Heart Failure

United States, Spain, Denmark, Israel, Germany, Italy
Guangdong Hengrui Pharmaceutical Co., Ltd

Enrolling by invitation

A Study to Assess the Efficacy and Tolerance of HRS-2261 in Subjects With Refractory Chronic Cough

Refractory Chronic Cough

China
Intermountain Health Care, Inc.
University of Utah

Active, not recruiting

Family Procedural Presence

Patient and Family Engagement

United States
GlaxoSmithKline

Completed

A Clinical Study to Assess Two Doses of GSK2402968 in Subjects With Duchenne Muscular Dystrophy (DMD) (DMD114876)

Muscular Dystrophies

United States
AFT Pharmaceuticals, Ltd.

Completed

Maxigesic IV Phase 3 Bunionectomy Study

Post Operative Pain

United States
Sanofi

Terminated

Drotaverine in Dysmenorrhoea Treatment

Dysmenorrhea

Hungary
Ottawa Hospital Research Institute

Recruiting

PDA Treatment With Ibuprofen and Changes in Tissue Oxygenation.

Patent Ductus Arteriosus After Premature Birth

Canada
Advanz Pharma

Completed

A Study of the Efficacy and Safety of Vernakalant Hydrochloride (MK-6621) in Patients With Atrial Fibrillation (MK-6621-010 AM4)

Atrial Fibrillation
Merck Sharp & Dohme LLC

Completed

A Study of a Bivalent Influenza Peptide Conjugate Vaccine in Healthy Adults

Influenza
Strategic Science & Technologies, LLC

Completed

Efficacy and Safety of SST 0225, a Topical Ibuprofen Cream, in the Treatment of Pain Associated With Acute Ankle Sprain

Acute Ankle Sprain

United States
Pfizer

Completed

Evaluation of the Efficacy of Novel Ibuprofen Acetaminophen Combination Formulations in the Treatment of Post-surgical Dental Pain

Pain

United States
University of Haifa

Unknown

Can Training Increase Reporting Accuracy and Study Power in Human Pain Trials

Healthy | Placebo Response

Israel
Rutgers, The State University of New Jersey

Terminated

IV Ibuprofen for Post-Electroconvulsive Therapy Myalgia

Depression, Myalgia

United States
Strategic Science & Technologies, LLC

Completed

Dosing Interval Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness (DIS DOMS)

Delayed Onset Muscle Soreness

United States
Johnson & Johnson Consumer and Personal Products...
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain

Pain
OSF Healthcare System

Terminated

Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates (OIDS)

Patent Ductus Arteriosus

United States
Organon and Co

Completed

Study of MK-0663/Etoricoxib in Postorthopedic Knee Replacement Surgery Pain (MK-0663-098)

Pain, Postoperative
Pfizer

Completed

A Study of Ibuprofen 250 mg / Acetaminophen 500 mg Comparing The Antipyretic Effects in Healthy Male Volunteers

Fever

United States
Boehringer Ingelheim

Completed

Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain

Pain, Postoperative | Tooth Diseases

United States
S.LAB (SOLOWAYS)
NMSI DENTMASTER

Not yet recruiting

A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults (ICLID)

Dental Pain

Russian Federation
University of California, Los Angeles
Sponsor Name Pending

Completed

Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure

Symptomatic Uterine Fibroids and Adenomyosis

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Ibuprofen From a Single Fixed Dose Combination Tablet of Ibuprofen and Caffeine Compared to Single Tablets of Ibuprofen and Ibuprofen Lysinate

Healthy

Germany
Bayer

Completed

A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women

Hot Flashes | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Canada
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

China

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