Search clinical trials for: Placebo: normal saline

Total 70429 results

Dompé Farmaceutici S.p.A

Completed

A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy Males

No Condition

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Dupilumab's Effects on Airway Inflammation in Patients With Asthma (EXPEDITION)

Asthma

Denmark, United States, Canada, Germany, Sweden, United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety Study of FP MDPI Compared With FS MDPI in Adolescent and Adult Patients With Persistent Asthma

Asthma

United States, Canada, Czechia, Hungary, Poland, Russian Federation, South Africa, Thailand, Ukraine
Alkermes, Inc.

Completed

A Study of ALKS 3831 in Adults With Schizophrenia

Schizophrenia

United States, Bulgaria, Czechia
Ain Shams University

Completed

Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy Surgery

Hemodynamic Instability

Egypt
Ain Shams University

Completed

Prophylactic Mirtazapine or Clonidine for Post-spinal Anesthesia Shivering

Shivering

Egypt
Reckitt Benckiser LLC
Premier Research Group plc; Aptuit Inc.

Completed

Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study

Post-operative Pain

United States
Wake Forest University
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy

Chronic Low Back Pain | Diabetic Neuropathic Pain

United States
Montefiore Medical Center

Completed

Orphenadrine and Methocarbamol for LBP

Low Back Pain

United States
Sutter Health

Completed

Nuedexta for the Treatment of Adults With Autism (Nuedexta)

Autism

United States
Par Pharmaceutical, Inc.
Novum Pharmaceutical Research Services

Terminated

Bioequivalence of Two Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspensions in Otitis Media in Children With Tympanostomy Tubes

Otitis Media in Patients With Tympanostomy Tubes

United States
Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
The First Affiliated Hospital with Nanjing Medical...
National Natural Science Foundation of China

Unknown

Different Platelet Activities Between Intracoronary and Peripheral Blood in Coronary Artery Disease Patients (DPABIAP)

Coronary Artery Disease

China
Merck Sharp & Dohme LLC

Completed

Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)

Pain, Postoperative Arthroscopy
Herbert Lindsley, MD

Completed

Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis

Osteoarthritis

United States
Orexigen Therapeutics, Inc

Completed

Study to Evaluate the Effect of Naltrexone and Bupropion Extended-Release Combination on Cardiac Repolarization in Healthy Participants

Heart Repolarization

United States
Vanderbilt University

Completed

Comparative Effects of Aspirin and NHP-544C

Healthy

United States
Astellas Pharma Europe B.V.

Completed

First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology

Healthy Volunteers

United Kingdom, Germany
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
Vanderbilt University
Forest Laboratories

Completed

Nebivolol in the Supine Hypertension of Autonomic Failure

Hypertension | Multiple System Atrophy | Pure Autonomic Failure

United States
GlaxoSmithKline

Withdrawn

A Study of IV Casopitant for the Prevention of Nausea and Vomiting Caused By Cisplatin-Based Highly Emetogenic Chemotherapy

Cancer | Solid Tumor Cancer | Chemotherapy-Induced Nausea and Vomiting | Nausea and Vomiting

United States, Canada
Boehringer Ingelheim

Completed

Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male and Female Volunteers

Healthy
Zalicus

Completed

Multicenter Study to Evaluate CRx-102 vs. Each of Its Components to Treat Active Rheumatoid Arthritis (MARS-1)

Rheumatoid Arthritis

United States, Poland, Argentina, Romania, Serbia, Canada, Estonia, Russian Federation, Lithuania, South Africa, Hungary, Mexico
Felipe Melo Cruz

Completed

Vitamin E for Oxaliplatin-induced Peripheral Neuropathy Prophylaxis

Peripheral Neuropathy

Brazil
Novartis

Completed

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

Type 2 Diabetes Mellitus | Impaired Glucose Tolerance

United States, Canada, Finland, Australia, Germany, India, Italy
Hospital de Clinicas de Porto Alegre

Unknown

Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome

Common Cold | Flu-like Syndrome

Brazil
National Cancer Institute (NCI)
NRG Oncology; Radiation Therapy Oncology Group

Completed

Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma | Gliosarcoma | Supratentorial Glioblastoma

United States, Canada, Israel
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Completed

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | RAS Wild Type

United States
Johns Hopkins University
Patient-Centered Outcomes Research Institute

Completed

Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple Sclerosis (TRIUMPHANT-MS)

Fatigue in Multiple Sclerosis

United States
Norma Osama Abdalla Zayed
Abdelhamid, Bassant Mohamed, M.D.

Completed

Effect of IV Infusion of Lidocaine Compared to IV Infusion of Dexmedetomidine on Proinflammatory Cytokines

Inflammatory Response

Egypt
Imperial College London
AstraZeneca

Completed

Effect of Symbicort on GR Localisation in Asthma

Asthma

United Kingdom
Postgraduate Institute of Medical Education and...

Completed

Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery

Opioid Free Anaesthesia

India
University of Washington
Fred Hutchinson Cancer Center; National Institute of General Medical Sciences...

Completed

Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions

Adverse Drug Interactions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Clofarabine and Low-Dose Total-Body Irradiation in Treating Patients With Acute Myeloid Leukemia Undergoing Donor Peripheral Blood Stem Cell Transplant

Acute Myeloid Leukemia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant

Acute Myeloid Leukemia | Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Plasma Cell Myeloma | Myelodysplastic/Myeloproliferative Neoplasm | Graft Versus Host Disease | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States, Italy
University Clinical Centre of Kosova
University of Ljubljana, Faculty of Medicine

Unknown

FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis

Type 2 Diabetes Mellitus | Periodontitis

Kosovo
German Hodgkin's Lymphoma Study Group
European Organisation for Research and Treatment of Cancer - EORTC; EBMT Solid...

Unknown

Combination Chemotherapy and Peripheral Stem Cell Transplant in Treating Patients With Relapsed Hodgkin's Lymphoma

Lymphoma

Poland, Belgium, Switzerland, Netherlands, Germany, Denmark, Croatia, Portugal
M.D. Anderson Cancer Center
Bayer

Terminated

Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma

Lymphoma

United States
National Cancer Institute (NCI)

Completed

Modified Stem Cell Transplant Procedure to Treat Patients With Blood and Immune System Cancers

Hematologic Neoplasms

United States
Friends Research Institute, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

Long-acting Naltrexone for Pre-release Prisoners

Opiate Addiction

United States
Cliniques universitaires Saint-Luc- Université...

Completed

Effect of Early Physical Exercise on Pulmonary Ventilation and Recruitment (EFRA)

Critical Illness

Belgium
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Dasatinib and Vorinostat in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Acute Lymphoblastic Leukemia

Leukemia

United States
Assistance Publique - Hôpitaux de Paris

Completed

Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence (CLOSE)

Ischemic Stroke | Migraine | Patent Foramen Ovale | Atrial Septal Aneurysm

France
Poitiers University Hospital
Sanofi; Intergroupe Francophone du Myelome

Active, not recruiting

Multicenter Open Label Phase 3 Study of Isatuximab Plus Lenalidomide and Dexamethasone With/Without Bortezomib in the Treatment of Newly Diagnosed Non Frail Transplant Ineligible Multiple Myeloma Elderly Patients (≥ 65; < 80 Years).

Multiple Myeloma | Myeloma

France
Amgen

Completed

Phase 3 Study of Carfilzomib, Melphalan, Prednisone vs Bortezomib, Melphalan, Prednisone in Newly Diagnosed Multiple Myeloma (CLARION)

Multiple Myeloma

Korea, Republic of, China, Spain, Taiwan, United States, Netherlands, Australia, Singapore, New Zealand, United Kingdom, Israel, France, Japan, Italy, Czechia, Belgium, Argentina, Austria, Bulgaria, Canada, Germany, Greece, Hungary, M... and more
European Myeloma Network
Universitaire Ziekenhuizen KU Leuven; University of Roma La Sapienza; Hospital... and other collaborators

Completed

Bortezomib, Dexamethasone, and Rituximab in Untreated Waldenstroms Macroglobulinemia (BDR-WM)

Waldenstroms Macroglobulinemia

Greece
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide With Radiation Therapy in Treating Patients With Glioblastoma Multiforme or Other Brain Tumors

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Guangdong Provincial People's Hospital

Completed

Induction Erlotinib Therapy in Stage III A (N2) Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer

Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Lymphoblastic Lymphoma | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute... and other conditions

United States, Germany, Italy
Hebei Medical University

Completed

The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure

Heart Failure

China

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