Search clinical trials for: Placebo Comparator

Total 54475 results

Royan Institute

Completed

The Effect of Ethinyl Estradiol on Polycystic Ovary Syndrome Women Undergoing Intrauterine Insemination

Infertility

Iran, Islamic Republic of
GlaxoSmithKline

Recruiting

Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple Myeloma (DREAMM 9)

Multiple Myeloma

Australia, Germany, Italy, Spain, United States, Korea, Republic of, Canada, France, Poland, United Kingdom
M.D. Anderson Cancer Center
Celgene Corporation

Completed

Temozolomide, Thalidomide, and Lomustine (TTL) in Melanoma Patients

Melanoma | Brain Neoplasms

United States
Massachusetts General Hospital

Completed

Lenalidomide/Bortezomib/Dexamethasone for Multiple Myeloma (MM) (RVD Lite)

Multiple Myeloma

United States
University of California, Davis
Eli Lilly and Company

Completed

Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors

Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
University of Copenhagen

Completed

Pharmacological Properties of Salmeterol

Pharmacokinetics in Healthy Young Men

Denmark
3M

Completed

Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty (PROMISES)

Pathologic Processes | Wounds and Injuries | Postoperative Complications | Surgical Wound | Infection | Musculoskeletal Disease | Prosthesis-Related Infections | Joint Disease | Revision Total Knee Arthroplasty

United States
The Lymphoma Academic Research Organisation
Millennium Pharmaceuticals, Inc.

Completed

Brentuximab Vedotin in Refractory/Relapsed Hodgkin Lymphoma Treated by ICE (BV-ICE)

Hodgkin Disease

France, Belgium
Boehringer Ingelheim

Completed

Open Label Study of NVP+CBV Treatment in Women Who Have Received sdNVP for the pMTCT of HIV

Acquired Immunodeficiency Syndrome

South Africa
Redar
Institut National de la Santé Et de la Recherche Médicale, France; Fondation... and other collaborators

Unknown

Ketamine's Efficiency in the Treatment of Chronic Pain: Kynurenin Pathway (KEKU1)

Inflammation | Chronic Pain | Neuralgia

France
Eurofarma Laboratorios S.A.

Withdrawn

A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study (SAVE)

Knee Osteoarthritis
China Medical University Hospital

Not yet recruiting

Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea

Obstructive Sleep Apnea of Adult
Aeovian Pharmaceuticals, Inc.

Recruiting

Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers

Healthy Participants

Australia
Rigshospitalet, Denmark

Recruiting

Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac Surgery (GLORIOUS-II)

Coronary Artery Disease | Aortic Valve Disease

Denmark
Joshua Woolley, MD/PhD

Recruiting

Psilocybin Therapy for Chronic Low Back Pain (POP)

Chronic Low-back Pain

United States
Carmen Clapp
Universidad Autónoma de Querétaro; Instituto Mexicano de Oftalmologia (IMO); General... and other collaborators

Recruiting

Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

Mexico
The University of Texas Health Science Center,...
Cures Within Reach

Completed

Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease

Irritability | Huntington Disease

United States
Shanghai Institute Of Biological Products
First Affiliated Hospital Bengbu Medical College

Completed

A Study Exploring Efficacy of Pegloticase in Subjects With Asymptomatic Hyperuricemia

Asymptomatic Hyperuricemia

China
Institut National de la Santé Et de la Recherche...

Completed

Trial of Treatments for COVID-19 in Hospitalized Adults (DisCoVeRy)

Corona Virus Infection

Norway, Austria, France, Greece, Portugal, Belgium, Luxembourg
St. Joseph's Healthcare Hamilton
Bausch Health, Canada Inc.

Active, not recruiting

A Trial Evaluating the Effectiveness of Contrave in Patients Who Have Weight Recidivism Following Bariatric Surgery (COR-WR)

Obesity

Canada
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); Eli Lilly and Company; Kanisa Pharmaceuticals

Completed

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

Myelodysplastic Syndromes | Leukemia

United States, Israel
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

Malignant Neoplasm

United States, Guam
Idorsia Pharmaceuticals Ltd.

Completed

To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.

Healthy Subjects

France
McGill University Health Centre/Research Institute...

Terminated

Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain (PRO_GENE_POP)

Postoperative Pain

Canada
Fred Hutchinson Cancer Center

Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Primary Myelofibrosis | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures

Malignant Neoplasm

United States
Ache Laboratorios Farmaceuticos S.A.

Suspended

Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu

Cold

Brazil
Brian J Lipworth

Completed

Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation

Allergic Rhinitis | Tachyphylaxis | Rhinitis Medicamentosa

United Kingdom
Merck Sharp & Dohme LLC

Completed

Study of MK-1029 in Participants With Persistent Asthma That Cannot Be Controlled With Montelukast (MK-1029-015)

Asthma
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects

Drug-induced Surface ECG Changes
Vanderbilt University Medical Center

Withdrawn

Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2

Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure NYHA Class I

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI); Otsuka America Pharmaceutical

Completed

Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen (LCCC0510)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability of Dupilumab in Patients With Persistent Moderate to Severe Eosinophilic Asthma

Asthma

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Withdrawn

Reduced Intensity Conditioning Before Partially Matched Donor Stem Cell Transplant in Treating Patients With Advanced Cutaneous T Cell Lymphoma

Recurrent Mycosis Fungoides and Sezary Syndrome | Cutaneous T-Cell Non-Hodgkin Lymphoma | Stage IIB Mycosis Fungoides and Sezary Syndrome | Stage IIIA Mycosis Fungoides and Sezary Syndrome | Stage IIIB Mycosis Fungoides and Sezary Syndrome | Stage IVA Mycosis Fungoides and Sezary Syndrome | Stage...
Bayer

Completed

Study of Nifedipine GITS and Candesartan Combination Compared to Monotherapy in Patients With Essential Hypertension (DISTINCT)

Hypertension, Essential

Spain, Argentina, United States, Canada, Korea, Republic of, Italy, Russian Federation, South Africa, Ukraine, Belgium, Brazil, Lithuania, United Kingdom
National Cancer Institute (NCI)

Completed

Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia

Rectal Cancer | Colon Cancer | Precancerous Condition

United States
Masoud Saatchi

Completed

Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis

Local Anesthesia
Hoffmann-La Roche

Completed

A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate (SCORE)

Rheumatoid Arthritis

Germany, Spain, Switzerland, Canada, Estonia, Greece, France, Russian Federation, Netherlands, Turkey, Serbia, Argentina, Latvia, Lithuania, Denmark, Romania, Brazil, Czech Republic, Norway
Orexigen Therapeutics, Inc

Completed

A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects

Obesity | Overweight

United States
Pfizer

Completed

Study Evaluating The Effects Of Bazedoxifene/Conjugated Estrogens On Endometrial Safety And Postmenopausal Osteoporosis

Menopause | Osteoporosis

United States, Colombia, Australia, Hungary, Poland, Finland, Argentina, Chile, Denmark, Mexico, New Zealand, Norway
Bankole Johnson
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Combined Pharmacotherapies for Alcoholism

Alcoholism

United States
Singapore National Eye Centre
International Stem Cell Forum

Completed

Thyroid Treatment Trial

Graves Ophthalmopathy

Singapore
AEterna Zentaris

Completed

Open Label Trial of Perifosine in Patients Currently Being Treated on Perifosine Trials in Solid Tumors or Multiple Myeloma

Non Small Cell Lung Cancer | Metastatic Breast Cancer | Solid Tumors | Sarcomas
Medical University of Lodz

Recruiting

The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients. (Dexa)

Postoperative Complications | Postoperative Pain | Vitamin D Deficiency | Hypocalcemia | Hypoparathyroidism Postprocedural | Postoperative Nausea | Voice Hoarseness

Poland
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating Patients With Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Carboplatin and Etoposide With or Without Oblimersen Sodium in Treating Patients With Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer

United States
Bristol-Myers Squibb

Terminated

Safety Study of Dasatinib With Bortezomib (Velcade®) and Dexamethasone for Multiple Myeloma

Multiple Myeloma

United States, Italy, France, Spain
Aalborg University

Not yet recruiting

Pharmacological Modulation of Peripheral Nerve Excitability

Peripheral Neuropathy

Denmark
OHSU Knight Cancer Institute
Oregon Health and Science University; Kuni Foundation

Recruiting

Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA Melanoma

Clinical Stage IIA Cutaneous Melanoma AJCC v8

United States

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