Search clinical trials for: Placebo; Sterile Saline

Total 63811 results

TrueBinding, Inc.

Recruiting

Sequential Dose-escalation Study to Assess the Safety, Tolerability and Pharmacokinetics of TB006 in Healthy Subjects (TB006SAD)

Alzheimer Disease

United States
GeneOne Life Science, Inc.

Not yet recruiting

GLS-1200 Topical Nasal Spray to Prevent Sinusitis After Endoscopic Sinus Surgery

Sinusitis Chronic

United States
Castle Creek Biosciences, LLC.

Terminated

Pilot Study of Azficel-T for the Treatment of Restrictive Burn Scars

Restrictive Burn Scars

United States
University of Miami
NovaBay Pharmaceuticals, Inc.

Terminated

Viral Conjunctivitis Treatment Study

Viral Conjunctivitis

United States
Tri-Service General Hospital

Completed

Fluid Restriction After Stapled Hemorrhoidopexy

Fluid Restriction

Taiwan
Janssen Research & Development, LLC

Recruiting

A Study of Sterile Saline Infusion in Healthy Volunteers

Healthy Volunteers

United States
Northwestern University
Icahn School of Medicine at Mount Sinai

Completed

The Efficacy and Safety of Secukinumab in Patients With Ichthyoses

Netherton Syndrome | Ichthyosis | Lamellar Ichthyosis | Autosomal Recessive Congenital Ichthyosis | Congenital Ichthyosiform Erythroderma | Epidermolytic Ichthyosis

United States
Dartmouth-Hitchcock Medical Center
Muhimbili University of Health and Allied Sciences

Completed

DAR-901 TB Booster Vaccine to Prevent TB in Adolescents (DAR-PIA)

Tuberculosis

Tanzania
Ajman University
Universitat Internacional de Catalunya

Active, not recruiting

Effect of Intra-Canal Cryotherapy on Postoperative Pain After Endodontic Procedures

Post Operative Pain | Endodontically Treated Teeth

United Arab Emirates
Castle Creek Biosciences, LLC.

Completed

Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia

Dysphonia Resulting From Vocal Fold Scarring | Age-related Dysphonia

United States
Clear Scientific, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants

Substance Use Disorders | Methamphetamine Abuse | Methamphetamine Intoxication

United States
European Vaccine Initiative
University of Oxford; Malaria Research and Training Center, Bamako, Mali

Not yet recruiting

Assessment of Safety, Immunogenicity and Efficacy of R21/Matrix-M1 Malaria Vaccine in Healthy WOCBP in Mali

Healthy Women of Child Bearing Potential
Jena University Hospital
German Federal Ministry of Education and Research

Not yet recruiting

Transfer of FRozen Encapsulated Multidonor Stool Filtrate for Active Ulcerative COlitis (FRESCO)

Inflammatory Bowel Diseases | Ulcerative Colitis
Biogen

Completed

Long-Term Assessment of Remyelinating Therapy (RENEWED)

Acute Optic Neuritis

Sweden, Spain, United Kingdom, Germany, Canada, Denmark, Hungary, Belgium, Czechia, Australia, Italy
Ionis Pharmaceuticals, Inc.
Bayer

Completed

A Study of Safety, PK, & PD of ISIS 416858 Administered Subcutaneously to Patients With End-Stage Renal Disease on Hemodialysis

End-stage Renal Disease (ESRD)

Canada
DynPort Vaccine Company LLC, A GDIT Company

Withdrawn

Phase 3, Randomized, Safety, Lot Consistency and Clinical Benefit Study of Recombinant Botulinum Vaccine A/B (rBV A/B)

Botulism
Stealth BioTherapeutics Inc.

Completed

The Impact of Intravenous Bendavia™ on Endothelial Reactivity Dysfunction in Cigarette Smoking

Healthy Volunteers

United States
Woman's Health University Hospital, Egypt

Unknown

Subcutaneous Sterile Water Injection for Relief of Low Back Pain

Low Back Pain
BioAegis Therapeutics Inc.

Not yet recruiting

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

Infections | Acute Respiratory Distress Syndrome
Hope Biosciences Stem Cell Research Foundation

Completed

Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome (HBPCOVID02)

Post COVID-19 Syndrome

United States
Biogen

Completed

BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Russian Federation
Ornge Transport Medicine

Withdrawn

The Ornge Comparison of Tracheal Occlusion Pressures to Ensure Safety Trial (OCTOPUS)

Barotrauma | Injury of Trachea | Friction and Pressure Injuries | Transfer/Transport Injury

Canada
Arrowhead Pharmaceuticals

Completed

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Dyslipidemias | Hypertriglyceridemia | Familial Hypercholesterolemia

Australia, New Zealand
Arrowhead Pharmaceuticals

Completed

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Hypertriglyceridemia | Familial Chylomicronemia

Australia, Canada, New Zealand
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Mayo Clinic

Completed

Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis (BMAC)

Bilateral Primary Osteoarthritis of Knee

United States
Alnylam Pharmaceuticals

Completed

A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects

Transthyretin-mediated Amyloidosis (ATTR Amyloidosis)

United Kingdom
Alnylam Pharmaceuticals
The Medicines Company

Completed

A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Hypercholesterolemia

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Elevated LDL-Cholesterol (LDL-C)

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis

Transthyretin Mediated Amyloidosis (ATTR)

United Kingdom, France, Portugal, Sweden
Hope Pharmaceuticals
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm

Subarachnoid Hemorrhage

United States
Wake Forest University Health Sciences

Terminated

Combined Spinal/Epidural (CSE) Saline Duration/Spread

Labor Pain

United States
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Arrowhead Pharmaceuticals

Completed

Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH

Non-alcoholic Steatohepatitis

New Zealand
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom
Arrowhead Pharmaceuticals

Completed

Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)

Hepatitis B

Australia, Hong Kong, New Zealand
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Istanbul University - Cerrahpasa (IUC)

Completed

The Effect of Bladder Stimulation Technique on Urine Specimen Collection in Newborns

Urine Specimen Collection

Turkey
Alnylam Pharmaceuticals

Completed

ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)

Amyloid Neuropathies | Amyloid Neuropathies, Familial | Amyloidosis, Hereditary | Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) | Amyloidosis, Hereditary, Transthyretin-Related | Familial Transthyretin Cardiac Amyloidosis

United States, France, Italy, Spain, Canada, Germany, Belgium, Sweden, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)

Acute Intermittent Porphyria

United States, United Kingdom, Sweden
Bowdoin College
National Institute of Mental Health (NIMH); MaineHealth

Completed

Vasopressin Effects on Human Social Communication (AVP)

Healthy

United States
Massachusetts General Hospital

Completed

L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1

Hereditary Sensory and Autonomic Neuropathy Type I

United States
Arbor Pharmaceuticals, Inc.

Terminated

Phase I Rising-dose Study to Assess Tolerability, Safety, Pharmacokinetics, Pharmacodynamics of AR09

Anesthesia

United States
Center for Human Reproduction
Foundation for Human Reproduction

Unknown

Effect of Influenza Vaccination on Donor Egg Recipient Outcomes (DE-FluVac)

Infertility | Recurrent Miscarriage

United States
Center for Human Reproduction
Foundation for Human Reproduction

Enrolling by invitation

Effect of Influenza Vaccination on IVF Outcomes - IVF (IVF-FluVac)

Infertility

United States
Regeneris Medical
Robert W. Alexander, MD, FICS; Global Alliance for Regenerative Medicine; Regeneris...

Unknown

Autologous Stem/Stromal Cells in Neurological Disorders and Disease (NDD)

Demyelinating Autoimmune Diseases, CNS | Dementia | Corticobasal Degeneration | Parkinson | Demyelinating Sensorimotor Neuropathy | Altered Behavior in Alzheimer Disease

United States
Ionis Pharmaceuticals, Inc.

Withdrawn

Safety and Efficacy of IONIS-FB-Lrx in up to 120 Patients 55 and Older With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

Geographic Atrophy | Age Related Macular Degeneration

Australia, United States, New Zealand

Search clinical trials for: Placebo; Sterile Saline

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