Search clinical trials for: Placebo - MAD

Total 55763 results

Hoffmann-La Roche

Completed

A Single Ascending And Multiple Ascending Dose Study of RO5271983 in Healthy Volunteers

Healthy Volunteer

New Zealand
Galapagos NV

Completed

A Study to Evaluate the Effects of a Single and Multiple Oral Doses of GLPG3121 in Adult, Healthy, Male Subjects

Healthy

Belgium
USDA Beltsville Human Nutrition Research Center
Penn State University

Completed

The Dose-Response Effects of Lean Beef in a Mediterranean-Style Dietary Pattern on Cardiovascular Disease Risk Factors

Healthy Volunteers

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of IBI356 in Healthy Participants and in Atopic Dermatitis Patients

Healthy Participants | Atopic Dermatitis Patients

China
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
R&G Pharma Studies Co.,Ltd.

Completed

To Evaluate the Safety, Tolerability, and Pharmacokinetics Profile in Healthy Chinese Volunteers of TG-2349

Healthy Chinese Volunteers

China
Shanghai Jiatan Pharmatech Co., Ltd

Completed

Sudapyridine (WX-081) in Healthy Volunteers

Healthy

China
ZYUS Life Sciences Inc.
Novotech (Australia) Pty Limited; ZYUS Life Sciences Australia Pty Ltd

Completed

Trichomylin® Safety, Tolerability & Pharmacokinetics in Healthy Adults and First in Human Osteoarthritis Pain Evaluation (HOPE)

Healthy | Osteoarthritis

Australia
EnnovaBio Australia Pharmaceuticals Pty Ltd

Not yet recruiting

A First-in-Human SAD/MAD Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ENC1018 in Healthy Adult Subjects

Healthy
Medgar Evers College, The City University of New...

Not yet recruiting

The Influence of Sound on Stress, Anxiety, and Mood

Healthy
Theravance Biopharma

Completed

SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects

Healthy

United States
Inmagene LLC

Completed

Study to Evaluate IMG-004 in Healthy Participants

Healthy Participants

United States
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects (CHF6333 FIH)

Cystic Fibrosis | Non-Cystic Fibrosis Bronchiectasis

Belgium
Hospital de Clinicas de Porto Alegre
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil; Conselho...

Unknown

ORal ApplianCes for sLeep Apnea of the Elderly (ORACLE)

Hypertension | Cardiovascular Disease | Obstructive Sleep Apnea

Brazil
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects

Healthy

Netherlands
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Pharmacobio

Recruiting

A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People

Alzheimer Disease

Korea, Republic of
Ji Xing Pharmaceuticals Australia Pty Ltd
Novotech (Australia) Pty Limited

Recruiting

JX09 SAD/MAD in Healthy Participants

Resistant Hypertension

Australia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
Cairo University

Unknown

E-max CAD Crowns Retained With Fiber Reinforced Composite Post Versus E-max CAD Endocrowns

Tooth Fractures | Debonding
Aptabio Therapeutics, Inc.

Completed

Safety, Tolerability, PK and PD of SAD or MAD of APX-115 in Healthy Male Volunteers

Healthy | Safety

France
University of Chicago

Completed

Patient Outcomes Reporting for Timely Assessments of Life With Depression: PORTAL-Depression

Depression | Depressive Disorder, Major

United States
7 Hills Pharma, LLC
Frontage Clinical Services, Inc.

Completed

A Phase 1 SAD and MAD Study of the Safety, Tolerability and PK of 7HP349 in Normal Healthy Male Subjects

Solid Tumor

United States
University Hospital, Grenoble

Unknown

Comparison of Efficacy of Two Mandibular Advancement Devices (MADs) During Sleep (SONAR)

Apnea Syndrome

France
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
ResMed

Recruiting

Long-term Benefits of CPAP or MAD Treatment on the Sleep of OSAS Patients (REMAP)

OSA

France
Johns Hopkins University

Withdrawn

Feasibility and Efficacy of Dietary Interventions for Older Adults With Subjective Cognitive Decline

Cognitive Impairment | Alzheimer Disease
VA Office of Research and Development

Completed

A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder

Obstructive Sleep Apnea

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease (STICH)

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Heart Failure, Congestive

United States
The VA Western New York Healthcare System

Unknown

A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder

Obstructive Sleep Apnea
University of Alberta

Recruiting

The Effect of Mandibular Advancement Devices on Markers of Cardiovascular Health in Obstructive Sleep Apnea Patients

Obstructive Sleep Apnea

Canada
University Hospital, Antwerp

Completed

Efficacy of Additional Titration During Oral Appliance Treatment for Sleep-disordered Breathing.

Obstructive Sleep Apnea Syndrome

Belgium
Centre hospitalier de l'Université de Montréal...

Recruiting

Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer. (Ronco-Onco)

Snoring | Sleep Apnea | Oral Cancer | Oral Squamous Cell Carcinoma | Pharynx Cancer

Canada
University of Barcelona

Suspended

Side Effects of the Mandibular Advancement Device for Apnea Treatment on Dental Occlusion and Masticatory Function

Obstructive Sleep Apnea

Spain
ethisch.comite@uza.be

Completed

PROMAD: Predicting Therapeutic Outcome of Mandibular Advancement Device Treatment in Obstructive Sleep Apnea (PROMAD)

Obstructive Sleep Apnea Syndrome

Belgium
Universidad Autonoma de Baja California

Completed

Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays

Medication Adherence | Medication Compliance

Mexico
All India Institute of Medical Sciences, New Delhi

Unknown

Dietary Therapy In Epilepsy Treatment (DIET-Trial): A Randomised Non Inferiority Trial Comparing KD, MAD & LGIT for Drug Resistant Epilepsy (DIET)

Drug Resistant Epilepsy

India
Maxinovel Pty., Ltd.

Not yet recruiting

A Study to Evaluate the Safety of MAX-40070 in Healthy Subjects

Alopecia Areata
UCSF Benioff Children's Hospital Oakland
National Cattlemen's Beef Association

Completed

The Effects of Natural Versus Man-Made Trans Fatty Acids on Lipoprotein Profiles: A Pilot Study

Cardiovascular Disease | Diabetes | Dyslipidemia

United States
Materia Medica Holding

Completed

Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Mild Cognitive Impairment in Early Recovery Stage After Ischemic Stroke

Ischemic Stroke | Mild Cognitive Impairment

Russian Federation
Beijing Jishuitan Hospital

Recruiting

A New Objective Titration Procedure for the Treatment of Mandibular Advancement Device in OSAHS Patients

Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)

China
Celal Bayar University

Recruiting

The Relationship With Mad Honey Containing Grayanotoxin and Ovary Tissue

Ovary Disease

Turkey
Case Western Reserve University

Completed

Mindfulness Attitude to Deliver Dietary Approach to Stop Hypertension (MADDASH)

Prehypertension
Materia Medica Holding

Completed

Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Cognitive Disorders in Patients With Ischemic Stroke in the Carotid Arteries

Cognitive Disorders

Russian Federation
JMackem Co., Ltd
Seoul National University Hospital

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects

Diabetic Neuropathies | Neuropathic Pain | Post Herpetic Neuralgia

Korea, Republic of
Materia Medica Holding

Completed

Prospecta in the Treatment of Cognitive, Behavioural and Psychiatric Disorders in Patients With Vascular Dementia.

Vascular Dementia

Russian Federation
Materia Medica Holding

Completed

Clinical Trial of Efficacy and Safety of Prospecta in the Treatment of Attention Deficit/Hyperactivity Disorder in Children

Attention Deficit Hyperactivity Disorder

Russian Federation
National University of Singapore
KHANA Center for Population Health Research

Recruiting

Community-Based Model for Delivery of Antiretroviral Therapy in Cambodia

HIV Infections | AIDS

Cambodia
University of Copenhagen
Sygekassernes Helsefond; Københavns Kommune; The Danish Dental Association; Postgraduate... and other collaborators

Active, not recruiting

Sleep, Upper Airway and Dental Occlusion in Children With Large Overjet

Overjet, Dental

Denmark
Guang'anmen Hospital of China Academy of Chinese...
Beijing Anzhen Hospital

Completed

Study of Herbal Formula Corresponding to Syndrome in Treating Post Percutaneous Coronary Intervention (PCI) Patients With Coronary Heart Disease (CHD)

Coronary Heart Disease

China

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