Search clinical trials for: Placebo matching BI 1358894

Total 1409 results

GlaxoSmithKline

Completed

Study to Evaluate the Efficacy, Safety and Tolerability of Bupropion Hydrochloride Extended-release Tablet, and Escitalopram Oxalate Capsule in Subjects With Major Depressive Disorder

Depressive Disorder, Major

China
Roger K. Pitman, MD

Completed

Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments

Post-traumatic Stress Disorder

United States
Seattle Children's Hospital
Children's Hospital of Philadelphia

Not yet recruiting

Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity

Craniopharyngioma | Hypothalamic Obesity | Hypothalamic Tumor

United States
GlaxoSmithKline
The General Hospital Corporation d/b/a Massachusetts General Hospital

Terminated

A Study Comparing the Effect of Albiglutide With Exenatide on Regional Brain Activity Related to Nausea in Healthy Subjects

Diabetes Mellitus

United States
McMaster University
Hamilton Health Sciences Corporation; Population Health Research Institute

Completed

PeriOperative ISchemic Evaluation-3 Trial: A Pilot Study (POISE-3)

Atherosclerotic Disease | Perioperative Bleeding

Canada
Arbor Pharmaceuticals, Inc.

Completed

Crossover Study to Evaluate the Efficacy of AR11 in Pediatric Patients With ADHD in a Laboratory Classroom Setting

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Merck Sharp & Dohme LLC

Completed

Study of the Safety, Tolerability, and Efficacy of Relebactam (MK-7655) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone to Treat Complicated Intra-Abdominal Infection [cIAI] (MK-7655-004)

Intra-abdominal Infections
Assiut University

Completed

Efficacy of Ketoprofen Before Hysterosalpingography

Pain Relief

Egypt
GlaxoSmithKline

Completed

A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263

Diabetes Mellitus, Type 2

United States
AstraZeneca

Terminated

Ph II Trial of Carboplatin and Pemetrexed With or Without AZD1775 for Untreated Lung Cancer

Previously Untreated Stage IV Non-Squamous Non Small Cell Lung Cancer

United States
Indiana University
BioAdvantex Pharma

Completed

N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults

HIV | Endothelial Dysfunction | Oxidative Stress

United States
University of Calgary

Not yet recruiting

Study of Ondansetron in the Prevention of Sleep Syncope: The Nineth Prevention of Syncope Trial (POST9) (POST9)

Sleep Syncope

Canada
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Recruiting

Enhancement of Stroke Rehabilitation With Levodopa (ESTREL)

Acute Stroke | Stroke Rehabilitation

Switzerland
Basilea Pharmaceutica

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

Fungal Infection

Netherlands
French Cardiology Society
Clinact; CLIPA

Completed

Non Steroidal Anti Inflammatory Treatment for Post Operative Pericardial Effusion

Pericardial Effusion

France
Boehringer Ingelheim

Completed

A Study in Men With Overweight to Test How Well Different Doses of BI 1820237 Are Tolerated When Given as an Injection Alone or in Combination With Liraglutide

Healthy

Germany
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 1356 BS in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2
Indiana University

Withdrawn

Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis

Arthritis, Rheumatoid | Vitamin D Deficiency

United States
University of Saskatchewan

Completed

Regular Use Tiotropium and Tolerance to Bronchoprotection in Mild Asthma

Asthma

Canada
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1 (NAC)

Cocaine Dependence

United States
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Pharmacokinetics, Safety and Tolerability of Sitagliptin in Adolescents (0431-081)

Type 2 Diabetes
Assiut University

Completed

Efficacy of Ketoprofen Before Intrauterine Device Insertion

Pain Relief

Egypt
University Hospital Tuebingen

Withdrawn

Dapagliflozin Effect on Erythropoiesis and Physical Fitness

Type 2 Diabetes Mellitus (T2DM)

Germany
Velicept Therapeutics, Inc.

Completed

A Study to Evaluate Once Daily Low Dose and High Dose Solabegron or Placebo Given for 12 Weeks to Treat Women With Symptoms of Overactive Bladder: Sudden Urge to Urinate, Frequent Urination Associated With Wetting Episodes (VEL-2001) (VEL-2001)

Overactive Bladder

United States
Cerimon Pharmaceuticals
PPD

Completed

Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain (SUPPORT 2)

Acute Pain | Ankle Sprain

United States
Scynexis, Inc.

Completed

Study to Evaluate the Safety and Efficacy of the Coadministration of Ibrexafungerp (SCY-078) With Voriconazole in Patients With Invasive Pulmonary Aspergillosis (SCYNERGIA)

Invasive Pulmonary Aspergillosis

United States, Belgium, Canada, Germany, South Africa
University of Erlangen-Nürnberg Medical School
Merck Sharp & Dohme LLC; Rush University Medical Center; HELIOS Kliniken GmbH

Terminated

Modulation of the Surgical Inflammatory Response by Etoricoxib

Pain | Postoperative Pain | Osteoarthritis, Hip

Germany
Repros Therapeutics Inc.

Completed

A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%

Secondary Hypogonadism

United States
Boehringer Ingelheim

Completed

Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers

Healthy

Germany
Centre Integre Universitaire de Sante et Services...

Recruiting

The Effects of Lemborexant on the Ability to Sleep During Daytime

Shift-Work Sleep Disorder

Canada
Hoffmann-La Roche

Active, not recruiting

A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Participants With Previously Untreated Advanced Non-Squamous Non-Small Cell Lung Cancer (SKYSCRAPER-06)

Non-small Cell Lung Cancer (NSCLC)

United States, Korea, Republic of, Canada, Belgium, China, Denmark, Spain, Thailand, United Kingdom, Taiwan, Brazil, Germany, Mexico, Italy, Switzerland, Hong Kong, Japan, France, Turkey, New Zealand, Poland
Bayer

Completed

A Multiple Dose Study of BAY1834845 in Healthy Male Subjects and in Patients With Psoriasis

Psoriasis | Healthy Volunteers

Germany
Velicept Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Solabegron Tablets for Treatment of Overactive Bladder in Adult Women

Overactive Bladder

United States
Merck Sharp & Dohme LLC

Completed

Effects of Suvorexant in Participants With Obstructive Sleep Apnea (MK-4305-036)

Sleep Apnea
University of Aarhus

Completed

Saving Residual Renal Function Among Haemodialysis Patients Receiving Irbesartan (SAFIR)

Kidney Failure, Chronic

Denmark
Tris Pharma, Inc.
Forest Laboratories

Completed

Efficacy and Safety of GRT6005 in Patients With Chronic Low Back Pain.

Low Back Pain

Austria, Belgium, Denmark, Finland, Germany, Hungary, Netherlands, Poland, Spain, Sweden, United Kingdom
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Zileuton to Treat Adults With Chronic Obstructive Pulmonary Disease (The LEUKO Study) (LEUKO)

Pulmonary Disease, Chronic Obstructive

United States
VA Office of Research and Development

Completed

Pharmacological Treatment of Generalized Anxiety Disorder in the Elderly (Sert-GAD)

Generalized Anxiety Disorder

United States
Stallergenes Greer

Completed

Dose Ranging Study of SLIT Tablets of House Dust Mite Allergen Extracts (HDM) in Adults With HDM-associated Allergic Asthma

Asthma | House Dust Mite Allergy

France, Germany, Poland
Jong Woo Chung
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

A Study on the Effect of Cilostazol in Patients With Chronic Tinnitus (CITI-ESR)

Tinnitus

Korea, Republic of
Boehringer Ingelheim

Completed

A Study to Test How Healthy Men Tolerate Different Doses of BI 1595043

Healthy

Belgium
Boehringer Ingelheim

Completed

A Study to Test How Well Healthy Men and Women Tolerate Different Doses of BI 706321

Healthy Volunteers

Belgium
Janssen Research & Development, LLC

Completed

A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

Depressive Disorder, Major

United States
Gilead Sciences

Completed

Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)

HIV-1 Infection

United States, Spain, United Kingdom, Netherlands, Germany, Canada, Sweden, Switzerland, Italy, Belgium, Puerto Rico, France
Boehringer Ingelheim

Completed

A Study in Healthy Men and Women to Test How Well Different Doses of BI 1323495 Are Tolerated

Healthy

Germany
Colorado State University

Completed

Cannabidiol Effects on Blood Alcohol Level and Intoxication

Alcohol Use Disorder

United States
International Partnership for Microbicides, Inc.

Withdrawn

A Safety and Pharmacokinetic Study for Dapivirine and Maraviroc Gel in Belgium

HIV Infections
Cerimon Pharmaceuticals
PPD

Completed

Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Soft Tissue Injuries (TAPED)

Acute Pain | Soft Tissue Injury

United States
Boehringer Ingelheim

Completed

This Study in Healthy Men Tests How Different Doses of BI 705564 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 705564 Affects the Way the Body Breaks Down Midazolam

Healthy

Germany
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Regeneration in Cervical Degenerative Myelopathy (RECEDE)

Spinal Cord Diseases | Myelopathy

United Kingdom

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