Search clinical trials for: Placebo to Upadacitinib

Total 60699 results

AstraZeneca

Completed

A Study of AZD4901 in Females With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome (PCOS), Female Endocrine Disorder

United States, United Kingdom, Germany
Merck Sharp & Dohme LLC

Completed

A Study of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus With Chronic Kidney Disease or Kidney Failure on Dialysis (MK-3102-019)

Type 2 Diabetes Mellitus
AbbVie

Completed

A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone

Rheumatoid Arthritis

United States, Bulgaria, Chile, Czechia, Hungary, Israel, Latvia, Mexico, Poland, Puerto Rico, Russian Federation, Slovakia, South Africa, Spain, Turkey, Ukraine
AbbVie (prior sponsor, Abbott)

Completed

A Study in Healthy Adults and Adult Subjects With Rheumatoid Arthritis to Evaluate the Safety, Tolerability and Pharmacokinetics After Multiple Doses of ABT-494

Rheumatoid Arthritis

United States
Gangnam Severance Hospital

Completed

Effect of Oral Carbohydrate on Serum S-100β Protein and Development of Postoperative Delirium in Elderly Patients

Inflammation | Delirium | Insulin Resistance
Merck Sharp & Dohme LLC

Completed

Letermovir Versus Valganciclovir to Prevent Human Cytomegalovirus Disease in Kidney Transplant Recipients (MK-8228-002)

CMV Disease

United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, France, Germany, Hungary, Italy, Mexico, New Zealand, Poland, Spain, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

Cystic Fibrosis

United States, Canada, Germany, United Kingdom
Protalix

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Gout

New Zealand
University of Pittsburgh
National Institutes of Health (NIH); Department of Health and Human Services

Completed

3-Week Parathyroid Hormone-related Protein (PTHrP) Dose Escalation Study in Post-Menopausal Women

Osteoporosis | Osteoporosis, Postmenopausal

United States
Assembly Biosciences

Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults

Chronic Hepatitis B

New Zealand
Vertex Pharmaceuticals Incorporated

Completed

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

Cystic Fibrosis

United States
Gilead Sciences

Completed

Sofosbuvir + Ribavirin for 12 or 16 Weeks in Treatment Experienced Subjects With Chronic Genotype 2 or 3 HCV Infection (FUSION) (FUSION)

Chronic Hepatitis C

United States, Canada, New Zealand, Puerto Rico
Jason Allen, Ph.D.

Terminated

Acute Effects of Beet Juice Consumption on Exercise Capacity in Heart Failure

Heart Failure

United States
Medical College of Wisconsin

Withdrawn

Pilot Study of the Effects of Resveratrol Supplement in Mild-to-moderate Alzheimer's Disease

Alzheimer Disease
Organon and Co

Completed

MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)

Hypertension
Organon and Co

Completed

A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)

Hypercholesterolemia
AlloVir

Completed

Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia

BK Virus Infection | BK Virus Nephropathy

United States
Cairo University

Unknown

Low Level Laser in Isolated Cleft Palate Repair Versus Surgical Correction Without LLL in Healing Process

Cleft Palate Children | Laser
Vivek Reddy
Abbott Medical Devices

Completed

Modified Ablation Guided by Ibutilide Use in Chronic Atrial Fibrillation (MAGIC-AF)

Persistent Atrial Fibrillation

Canada, United States, Korea, Republic of
ObsEva SA

Completed

Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids (PRIMROSE 1)

Uterine Fibroids | Heavy Menstrual Bleeding

United States
Hospital de Clinicas de Porto Alegre

Unknown

Rhodiola Rosea in Adults With Attention Deficit/Hyperactivity Disorder

Attention Deficit/Hyperactivity Disorder

Brazil
Aswan University Hospital

Unknown

Sublingual Misoprostol and Tranexamic Acid in Pregnant Women With Twin Pregnancy Undergoing Cesarean Section

Cesarean Section Complications

Egypt
Organon and Co

Completed

A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants With High Cholesterol (MK-0653C-190 AM1)

Hypercholesterolemia
University Hospital, Toulouse

Completed

Oxytocin Intranasal Administrations in Children With Prader-Willi Syndrome Aged From 3 to 12 Years (Oxyjeune)

Prader-Willi Syndrome

France
Guangdong Raynovent Biotech Co., Ltd

Completed

A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A

Influenza A

China
ObsEva SA

Completed

Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids (PRIMROSE 2)

Uterine Fibroids | Heavy Menstrual Bleeding

United States, Bulgaria, Czechia, Hungary, Latvia, Lithuania, Poland, Romania, Ukraine
Gilead Sciences

Completed

Sofosbuvir and Ribavirin in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 2 or 3 HCV Infection

Hepatitis C

Spain, Netherlands, Austria, France, United Kingdom, Italy, Estonia, Germany, Poland, Sweden
Medical University of Vienna

Completed

Additive Homeopathy in Cancer Patients (HIC)

Malignant Tumors

Austria
Vera Therapeutics, Inc.

Recruiting

Atacicept in Subjects With IgA Nephropathy (ORIGIN 3)

IgA Nephropathy | Berger Disease

United States
Medicines for Malaria Venture
University of Cape Town

Completed

Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers

Malaria

South Africa
Aswan University Hospital

Unknown

Foley's Catheter Balloon Plus Tranexamic Acid During Cesarean Delivery for Placenta Previa

Placenta Previa

Egypt
Gilead Sciences

Recruiting

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy (ARTISTRY-2)

HIV-1-infection

United States, Japan, Puerto Rico, Australia, Canada
Instituto de Investigación Sanitaria de la Fundación...
Hospital Universitario de Móstoles

Not yet recruiting

Response to Upadacitinib of Enthesitis Evaluated by Ultrasound in Patients With Psoriatic Arthritis

Psoriatic Arthritis

Spain
AbbVie

Recruiting

A Study to Assess Disease Activity in Adult Participants With Axial Spondyloarthritis Who Receive Upadacitinib in a Real-world Setting (UpSPINE)

Axial Spondylarthritis (r-axSpA)

Germany
Merck Sharp & Dohme LLC

Active, not recruiting

Dose Ranging, Switch Study of Islatravir (ISL) and Ulonivirine (MK-8507) Once-Weekly in Virologically-Suppressed Adults With Human Immunodeficiency Virus Type 1 (HIV-1) [MK-8591-013]

HIV-1 Infection

United States, France, Switzerland
Merck Sharp & Dohme LLC

Completed

Telcagepant (MK-0974) Long-Term Safety Study in Adult Participants With Acute Migraine (MK-0974-012)

Migraine
Alyatec

Completed

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Mite Allergic Subjects With Asthma

Allergy | Allergic Asthma | Allergy to House Dust

France
AbbVie

Active, not recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis (Level Up)

Atopic Dermatitis

United States, Australia, Belgium, Bulgaria, Canada, China, Denmark, France, Germany, Hungary, Italy, Korea, Republic of, Mexico, Netherlands, Poland, Portugal, Puerto Rico, Romania, Slovakia, South Africa, Spain, Sweden, Switzerland, Taiwa... and more
Sixth Affiliated Hospital, Sun Yat-sen University

Completed

Efficacy and Safety Analysis of Upadacitinib in Inflammatory Bowel Disease

Inflammatory Bowel Diseases

China
AbbVie

No longer available

Expanded Access to Upadacitinib

Atopic Dermatitis (AD)
Merck Sharp & Dohme LLC

Active, not recruiting

Switch to Doravirine/Islatravir (DOR/ISL) in Human Immunodeficiency Virus 1 (HIV-1) Participants Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-018)

HIV Infection

United States, Australia, Austria, Canada, Finland, France, Germany, Italy, Japan, Puerto Rico, Spain
Merck Sharp & Dohme LLC

Completed

Islatravir (MK-8591) With Doravirine and Lamivudine in Participants Infected With Human Immunodeficiency Virus Type 1 (MK-8591-011)

HIV-1 Infection

United States, Chile, France, United Kingdom
hany farouk

Unknown

Buccal Misoprostol and Intravenous Tranexamic Acid During Emergent Cesarean Delivery

Cesarean Section Complications

Egypt
University Hospital, Strasbourg, France

Withdrawn

Role of Indoor Pollutants on House Dust Mite Allergic Asthma

Allergic Asthma | Allergy to House Dust Mite

France
University of the Incarnate Word
National Eye Institute (NEI)

Completed

Impact of Color Correcting Lenses on Color Vision Deficiency

Color Vision Defects | Color Blindness | Color Blindness, Red | Color Blindness, Green

United States
Rhythm Pharmaceuticals, Inc.

Recruiting

A Study of RM-718 in Healthy Subjects and in Patients With HO

Hypothalamic Obesity

United States
Kallyope Inc.

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus (T2DM)

United States
Taisho Pharmaceutical Co., Ltd.

Completed

Phase III Study of TS-142 in Patients With Insomnia

Patients With Insomnia

Japan
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 135585 XX in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Germany
Boehringer Ingelheim

Completed

Single Rising Dose Study (Intravenous Infusion and Subcutaneous Injection) of BI 655064 in Healthy Male Volunteers

Healthy

Germany

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