Search clinical trials for: Placebo to match aficamten

Total 1421 results

Taisho Pharmaceutical Co., Ltd.

Completed

A Clinical Pharmacology Study of TS-142 in Patients With Obstructive Sleep Apnea Hypopnea.

Patients With Mild Obstructive Sleep Apnea Hypopnea

Japan
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of SAF312 in Patients With Neurogenic Detrusor Overactivity Due to Spinal Cord Lesions

Neurogenic Urinary Bladder | Neurogenic Bladder Disorder | Neurogenic Dysfunction of the Urinary Bladder | Neurogenic Bladder, Uninhibited | Neurogenic Bladder, Spastic

Netherlands, Germany, Switzerland
Merck Sharp & Dohme LLC

Completed

A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006)

Genital Warts | Cervical Cancers | Vulvar Cancers | Vaginal Cancers
Albert Einstein College of Medicine
National Institute on Aging (NIA)

Completed

Acute Effects of Cannabis on Cognition and Mobility in Older HIV-infected and HIV-Un-infected Women

HIV | Aging | AIDS

United States
Novartis Pharmaceuticals
National Institute on Aging (NIA); Amgen; Banner Alzheimer's Institute

Terminated

A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (GS1)

Alzheimers Disease

United States, Belgium, United Kingdom, Germany, Australia, Canada, Spain, Finland, Switzerland, Netherlands
Assiut University

Unknown

Use of Nitroglycerine to Improve Signs of Poor Peripheral Perfusion in Patients With Traumatic Hemorrhagic Shock

Hemorrhagic Shock

Egypt
Charles University, Czech Republic

Active, not recruiting

Non Motoric Reactions in Vojta Reflex Locomotion (VojtaRL)

Locomotion Disorder, Neurologic

Czechia
Taisho Pharmaceutical Co., Ltd.

Completed

Early Phase 2 Clinical Study of TS-142 in Patients With Insomnia Disorder

Insomnia Disorder

Japan
Merck Sharp & Dohme LLC

Completed

Polysomnography Study of MK-6096 in Participants With Primary Insomnia (MK-6096-011)

Primary Insomnia
Panacea Biotec Ltd

Completed

To Evaluate the Dose Response of 3 Doses of Euphorbia Prostrata in Patients With First and Second Degree Hemorrhoids

Hemorrhoids

India
McNeil AB

Completed

Skin Sensitization Potential of a New Nicotine Patch

Smoking Cessation

Germany
University of Illinois at Chicago

Recruiting

Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental Approach (CLEAR-3)

Suicidal Ideation

United States
Boehringer Ingelheim

Completed

Evaluation of Photosafety of BI 730357 Compared to Placebo and the Known Photosensitizing Agent Ciprofloxacin

Healthy

United States
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Three-times Weekly Dosing in Dialysis (ASCEND-TD)

Anaemia

Korea, Republic of, Russian Federation, Spain, United States, Australia, United Kingdom, Brazil, Italy, Argentina, Poland, Romania, France, Canada
Jiangsu Hansoh Pharmaceutical Co., Ltd.
Nanjing Medical University

Completed

Phase II Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg Positive Chronic Hepatitis B (PEG-Tα1)

Hepatitis B, Chronic

China
Emory University
National Institute of Mental Health (NIMH)

Recruiting

Neuroendocrine Risk for PTSD in Women

PTSD | Trauma

United States
Aalborg University
European Commission; Danish National Research Foundation

Completed

Measuring and Modulating Changes in EEG Resting State Functional Connectivity During Short-term and Long-term Pain

Prolonged Pain, EEG, Resting State Functional Connectivity

Denmark
Massachusetts General Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Androgen Effects in HIV-infected Women

HIV Infection

United States
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sympatholysis in Chronic Kidney Disease (Sym-CKD)

Chronic Kidney Disease

United States
Merck Sharp & Dohme LLC

Completed

Three-Dose Regimen of MRKAd5+6 Trigene (V526) in Healthy Adults (V526-001)(COMPLETED)

HIV Infections | HIV
University of North Carolina, Chapel Hill
National Institute of Mental Health (NIMH)

Completed

Effect of Perimenstrual Ovarian Steroid Supplementation on Perimenstrual Suicidality

Suicidal Ideation

United States
ZARS Pharma Inc.

Completed

Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Chronic, Moderate to Severe Osteoarthritis (OA) Pain

Pain

United States
Bayer

Completed

A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women

Hot Flashes | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Canada
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis

Cystic Fibrosis

Netherlands, United Kingdom
Novartis Pharmaceuticals

Completed

Safety and Efficacy of DNK333 in Atopic Dermatitis Patients

Pruritus in Patients With Atopic Dermatitis

Germany
West China Hospital

Completed

A Study on the Effectiveness of WeChat-based Online Education to Reduce Perioperative Anxiety in Breast Cancer Patients

Breast Cancer Female

China
AstraZeneca

Completed

Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD

Poland, United Kingdom, Germany, Sweden, Denmark
Bayer

Terminated

A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT) (REMOTE-HF)

Chronic Heart Failure

United States, Spain, Denmark, Israel, Germany, Italy
Guangdong Hengrui Pharmaceutical Co., Ltd

Enrolling by invitation

A Study to Assess the Efficacy and Tolerance of HRS-2261 in Subjects With Refractory Chronic Cough

Refractory Chronic Cough

China
Intermountain Health Care, Inc.
University of Utah

Active, not recruiting

Family Procedural Presence

Patient and Family Engagement

United States
Crucell Holland BV

Completed

A Study to Evaluate the Immunogenicity, Safety and Tolerability of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult Participants

Healthy

United States
Advanz Pharma

Completed

A Study of the Efficacy and Safety of Vernakalant Hydrochloride (MK-6621) in Patients With Atrial Fibrillation (MK-6621-010 AM4)

Atrial Fibrillation
Merck Sharp & Dohme LLC

Completed

A Study of a Bivalent Influenza Peptide Conjugate Vaccine in Healthy Adults

Influenza
Jiangsu Hansoh Pharmaceutical Co., Ltd.
Nanjing Medical University

Unknown

Phase Ⅲ Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg-positive Chronic Hepatitis B (PEG-Tα1)

Hepatitis B, Chronic

China
Centre for Addiction and Mental Health
Ottawa Heart Institute Research Corporation; Canadian Cancer Society (CCS)

Completed

Personalized Dosing of Nicotine Replacement (NRT to Effect)

Tobacco Use Disorder | Nicotine Dependence

Canada
Ono Pharmaceutical Co. Ltd

Terminated

A Four-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-5788 in Healthy Adult Volunteers

Acromegaly

United States
Murdoch Childrens Research Institute

Suspended

Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? The D-Vex Pilot Study (D-Vex)

Atopic Dermatitis

Australia
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

China
Universidade Federal do Ceara

Completed

Effects of Auriculotherapy on Pain and Functional Capacity of Individuals With Chikungunya Fever

Chikungunya Fever

Brazil
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of BI 113608 in Healthy Male Volunteers

Healthy

Germany
Brigham and Women's Hospital
National Cancer Institute (NCI); Mayo Clinic; Albert Einstein College of Medicine and other collaborators

Completed

KEEPS Mammographic Density And Breast Health Ancillary Study (KEEPS MDBHAS)

Mammographic Density | Abnormal Mammogram

United States
Purdue Pharma LP

Completed

Buprenorphine Accumulation and Description of Its Metabolites During Co-Medication of Buprenorphine Transdermal System (BTDS) and Ketoconazole

Healthy

United States
ZARS Pharma Inc.

Terminated

Fentanyl Transdermal Patch With CHADD™ for Breakthrough Pain in Patients With Moderate to Severe Non-Malignant Pain

Pain

United States
The Scripps Research Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Tobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone)

Smoking | Alcoholism

United States
Shire

Terminated

Evaluation of Ecallantide for Treatment of Angiotensin Converting Enzyme (ACE) Inhibitor Induced Angioedema

ACE Inhibitor Induced Angioedema

United States
Vibe G Frøkjær, MD, PhD
Hvidovre University Hospital; Herlev Hospital

Recruiting

Maternal Mental Health Trial (MAMA)

Postpartum Depression | Major Depressive Disorder

Denmark
ACELYRIN Inc.

Completed

Hidradenitis Suppurativa Phase 2b Pivotal Study of Izokibep

Hidradenitis Suppurativa

United States, Canada, Germany, Hungary, Poland, Spain
Theratocular Biotek Co.
Novotech (Australia) Pty Limited

Active, not recruiting

A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

Australia
Pennington Biomedical Research Center
THE C.B. AND IRENE PENNINGTON FOUNDATION

Completed

Postpartum Weight Loss and Exercise (PRIDE) (PRIDE)

Glucose Intolerance | Gestational Diabetes

United States
AstraZeneca

Completed

Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD)

Sensitivity in Esophagus

Denmark, Sweden

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