Search clinical trials for: Propofol anesthesia

Total 8575 results

Tang-Du Hospital

Unknown

Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia

General Anesthesia

China
Pfizer

Completed

Drug-Drug Interaction Study With PF-05089771

Healthy

Belgium
University of Dublin, Trinity College
Alzheimer's Association

Recruiting

Diminishing Accelerated Long-term Forgetting in Mild Cognitive Impairment

Mild Cognitive Impairment | Memory Impairment | Memory Disorders in Old Age

Ireland
University of Alberta

Completed

Laparoscopically Guided Rectus Sheath Block in Pediatric Appendicitis

Appendicitis Acute

Canada
New Approaches to Neuroblastoma Therapy Consortium
National Cancer Institute (NCI)

Active, not recruiting

N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan (DFMO)

Neuroblastoma

Canada, United States, Australia
ImmunityBio, Inc.

Active, not recruiting

QUILT-3.067: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With TNBC Who Have Progressed on or After Standard-of-care Therapy.

Triple Negative Breast Cancer

United States
Cetylite Industries

Completed

Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers

No Disease State or Condition

United States
University Hospitals Cleveland Medical Center

Terminated

Efficacy of Buprenorphine on Postoperative Endodontic Analgesia (EBPEA)

Postoperative Pain

United States
National Cancer Institute (NCI)

Active, not recruiting

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Glioblastoma | WHO Grade 3 Glioma | Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Glioma | Recurrent Cholangiocarcinoma | WHO Grade 2 Glioma

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis (RIISC-THETIS)

Myocardial Infarction | Stroke | Atherosclerosis | Cerebral Infarction | Stroke, Ischemic | Cardiac Disease | Coronary Syndrome | TIA

France
Universitätsklinikum Hamburg-Eppendorf

Completed

Prospective Evaluation of Topical Anesthesia in Children (LET)

Skin Lacerations

Germany
Imam Abdulrahman Bin Faisal University

Completed

Effect of a Vibration System on Pain Reduction During Injection of Local Dental Anaesthesia in Children

Dental Anxiety | Local Anaesthetic

Saudi Arabia
University of Parma

Completed

Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia

Foot Diseases | Injuries, Knee | Orthopedic Disorders | Injuries, Leg | Injuries, Foot

Italy
Intarcia Therapeutics

Completed

Study of the Effects of ITCA 650 on Gastric Emptying and Interaction of ITCA 650 on 4 Commonly Studied Drugs

Healthy

United States
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
Biogen

Completed

An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis (OBSERVE)

Relapsing-Remitting Multiple Sclerosis

Poland, Hungary, United States, Czech Republic
Sylhet M.A.G.Osmani Medical College
University of Edinburgh

Completed

Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning (SalbutamolOP)

Organophosphate Poisoning

Bangladesh
Eurofarma Laboratorios S.A.

Not yet recruiting

Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR) (TRIPLAR)

Chronic Obstructive Pulmonary Disease

Brazil
Lawson Health Research Institute

Not yet recruiting

Perioperative Pain Management for Total Shoulder Arthroplasty: A Pilot Non-Inferiority Trial

Anesthesia, Local | Local Infiltration | Shoulder Arthritis

Canada
University Hospital, Angers

Recruiting

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR (BIG-1)

Acute Myeloid Leukemia (AML)

France
Ain Shams University

Completed

Intranasal vs Buccal vs Intramuscular Midazolam for the Home and Emergency Treatment of Acute Seizures

Convulsions

Egypt
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers

Chronic Hepatitis B

China
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Chronic Pain | Postoperative Pain | Analgesics

Denmark
Seoul National University Hospital

Completed

Evaluation and Validation of Metabolic Markers for the Assessment of CYP3A Activity and Prediction of DDI (CYP3A_weak)

Healthy
First Affiliated Hospital of Harbin Medical University

Unknown

The Effect of Parecoxib Sodium Intravenous Patient-controlled Analgesia in Laparotomic Liver Resection

Pain, Postoperative

China
Baskent University

Completed

Effects of Dexmedetomidine Premedication on Geriatric Patients With Chronic Renal Failure Undergoing Hip Surgery

Hip Fracture | Chronic Renal Failure

Turkey
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
Magna Pharmaceuticals, Inc.

Unknown

StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study

Rhinitis, Seasonal, Allergic

United States
AstraZeneca

Completed

Drug Interaction Study Between AZD3480 and Cytochrome P450 (Cocktail)

Alzheimer's Disease | Metabolism

Sweden
St. Jude Children's Research Hospital

Recruiting

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Myeloid Sarcoma | Chronic Myeloid Leukemia (CML) | Non-Hodgkin Lymphoma (NHL) | Juvenile Myelomonocytic Leukemia (JMML)

United States
University Hospital, Ghent

Completed

Multimodal Versus Opioid aNalgesia in carDiAc Surgery (MONDAY)

Postoperative Pain | Postoperative Delirium

Belgium
Spanish Breast Cancer Research Group
Merck Sharp & Dohme LLC

Completed

Incidence of Chemotherapy-Induced Nausea and Vomiting Associated With Docetaxel-Cyclophosphamide in Early Breast Cancer.

Breast Cancer

Spain
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Malaria

United Kingdom
Takeda

Withdrawn

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Crohn Disease | Colitis, Ulcerative

United States
Andrew A Herring
University of California, Los Angeles; Oregon Health and Science University

Unknown

US-guided SAPB for Rib Fractures in the ED

Rib Fractures | Rib Fracture Multiple

United States
University of Nebraska
National Cancer Institute (NCI)

Completed

Vaccine Therapy Plus Sargramostim Following Chemotherapy in Previously Untreated Aggressive Non-Hodgkin's Lymphoma

Lymphoma

United States
AstraZeneca
Fortrea

Not yet recruiting

Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma. (ARRIVAL)

Severe Asthma
The Cleveland Clinic
Murdoch University

Terminated

Mechanism and Treatment of Sympathetically Maintained Pain

Complex Regional Pain Syndrome (CRPS)

United States
Chosun University Hospital

Completed

Effect of Dexmedetomidine After Thyroidectomy

Thyroid Tumor

Korea, Republic of
Biomedical Development Corporation
The University of Texas Health Science Center, Houston; National Institute...

Completed

New Topical Treatment for Continued Pain After Shingles

Postherpetic Neuralgia

United States
Mirati Therapeutics Inc.

Completed

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Advanced Solid Tumor

United States
Amgen

Active, not recruiting

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
Novartis Pharmaceuticals

Withdrawn

HDM201 Added to CT in R/R or Newly Diagnosed AML

Leukemia, Myeloid, Acute
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Ibrutinib on the Pharmacokinetics of Oral Contraceptives, CYP2B6, and CYP3A4 Substrates in Female Participants With B Cell Malignancy

Leukemia, Lymphocytic, Chronic, B-Cell

Spain, Poland
HTL-Strefa S.A.

Completed

Characteristics of Different Types of Safety Lancets on Blood Volume and Perceived Pain in Male and Female Volunteers

Healthy

Poland
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates

Rheumatoid Arthritis

United States
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
AstraZeneca

Completed

A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate (AZD3293DDI)

Healthy Volunteers | Pharmacologic Action

United States

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