Search clinical trials for: Prostacyclin Receptor Agonist

Total 21612 results

Actelion

Completed

A Study of Single and Multiple Doses of Different Formulations of a Prostacyclin Receptor Agonist

Pulmonary Arterial Hypertension

United States
Rune Rasmussen

Completed

Effects of Prostacyclin Infusion on Cerebral Vessels and Metabolism in Patients With Subarachnoid Haemorrhage

Subarachnoid Hemorrhage

Denmark
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Cambridge; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix)

Pulmonary Arterial Hypertension

United Kingdom
University of California, Los Angeles
Actelion

Terminated

Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart Disease

Pulmonary Arterial Hypertension | Congenital Heart Disease | Eisenmenger's Syndrome

United States
United Therapeutics

Completed

Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies (Aspire)

Pulmonary Arterial Hypertension

United States
Free University Medical Center

Completed

Epoprostenol in Pulmonary Embolism

Acute Pulmonary Embolism

Netherlands
Glostrup University Hospital, Copenhagen

Unknown

Migraine Inducing Effects and Changes in Brain Haemodynamics of PGI2

Migraine | Headache | Vasodilatation

Denmark
Liquidia Technologies, Inc.
Nuventra, Inc.

Completed

Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil (INSPIRE)

Primary Pulmonary Hypertension

United States
Sir Run Run Shaw Hospital

Recruiting

Hetrombopag for the Thrombocytopenia Induced by Concurrent Chemoradiotherapy

Thrombocytopenia | Radiotherapy Side Effect

China
Liquidia Technologies, Inc.
Nuventra, Inc.

Active, not recruiting

Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil

Primary Pulmonary Hypertension

United States
University of Florida
National Institute of General Medical Sciences (NIGMS); Surgical Infection...

Completed

Novel Mechanisms and Approaches to Treat Neonatal Sepsis

Immunologic Deficiency Syndromes | Complication of Prematurity

United States
Guang'anmen Hospital of China Academy of Chinese...
Ministry of Science and Technology of the People´s Republic of China

Completed

Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial

Constipation
Catholic University of the Sacred Heart

Completed

Prostacyclin's Effect on Platelet Responsiveness

Acute Kidney Failure

Italy
Rigshospitalet, Denmark

Completed

Effect of Prostacyclin on Haemostasis in Abdominal Surgery

Surgery

Denmark
University Hospital, Lille
Groupement Interrégional de Recherche Clinique et d'Innovation; Région Nord-Pas...

Unknown

Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use Disorder (BACLOPHONE)

Alcohol Use Disorder

France
University of Missouri-Columbia
American Society for Metabolic and Bariatric Surgery

Recruiting

Impact GLP-1 Agonists Following Bariatric

Hypertension | Diabetes Mellitus | Metabolic Syndrome | Morbid Obesity | Obstructive Sleep Apnea of Adult

United States
Eli Lilly and Company

Completed

A Study of LY2828360 in Patients With Osteoarthritic Knee Pain

Osteoarthritis, Knee

Denmark
Aaron Cypess
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Effects of b3-Adrenergic Receptor Agonists on Brown Adipose Tissue

Obesity

United States
Liquidia Technologies, Inc.
FGK Clinical Research GmbH

Terminated

Hemodynamic Evaluation of Dose-response and Safety of Dry Powder Inhalation of Treprostinil

Pulmonary Arterial Hypertension

France, Germany
Motus Therapeutics, Inc.
Michael J. Fox Foundation for Parkinson's Research

Terminated

A Phase 2 Study to Evaluate the Safety and Efficacy of RM-131 in Patients With Parkinson's Disease & Chronic Constipation (MOVE-PD)

Parkinson's Disease

United States
Henning Bundgaard

Completed

Beta 3 Agonist Treatment in Heart Failure (Beat-HF)

Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)

Australia, Denmark
University of Mississippi Medical Center

Recruiting

Effect of GLP-1 Receptor Agonists on Trabecular Bone Score

Diabetes Mellitus, Type 2 | Osteoporosis, Postmenopausal

United States
Benha University

Recruiting

Ocular Changes With Alpha-2 Receptor Agonist.

Glaucoma, Suspect | Aberration, Corneal Wavefront

Egypt
University of Chicago
National Institute on Drug Abuse (NIDA)

Completed

Mood Effects of Serotonin Agonists Extended (MESA-E)

Healthy

United States
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients

Adverse Effect
Roswell Park Cancer Institute
Cleveland BioLabs, Inc.

Completed

Entolimod in Treating Patients With Locally Advanced or Metastatic Solid Tumors That Cannot Be Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

Response Rate and Duration After Discontinuation Thrombopoietin Receptor Agonists Primary Immune Thrombocytopenia

Immune Thrombocytopenia

Italy
General Hospital of Ningxia Medical University

Recruiting

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension

Outcome

China
Dasman Diabetes Institute

Recruiting

Relationship Between Improvement in Insulin Secretion and Decrease in HbA1c in GLP-1 RA Therapy in T2DM Patients

Diabetes Mellitus, Type 2

Kuwait
Piramal Enterprises Limited
Quintiles, Inc.; Miami Research Associates

Unknown

Determination of Safety,Tolerability,Pharmacokinetics,Food Effect& Pharmacodynamics of Single & Multiple Doses of P11187

Overweight | Diabetes Mellitus Type 2 in Obese

United States
University Hospital, Gentofte, Copenhagen
University of Copenhagen; Steno Diabetes Center Copenhagen

Completed

The Effect of GIP(3-30)NH2 (GA-10)

Endocrine - Other

Denmark
National University of Natural Medicine
US Department of Veterans Affairs

Not yet recruiting

Remote Yoga Nidra for Deprescribing BZRAs

Insomnia | Anxiety
General Hospital of Ningxia Medical University

Recruiting

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension in Preeclamptic Patients

Adverse Effect

China
Targacept Inc.

Completed

A Safety and Efficacy Study of Ispronicline (TC-1734-112) in Subjects With Age Associated Memory Impairment (AAMI)

Age-Related Memory Disorders

United States
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment

Adverse Effect
University Health Network, Toronto

Completed

Nebulized Epoprostenol (FLOLAN) and Phenylephrine on One Lung Ventilation (OLV) (FLOLAN)

Oxygenation During One Lung Ventilation

Canada
General Hospital of Ningxia Medical University

Not yet recruiting

Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic Patients

Adverse Effect
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients

Adverse Effect
National Institute of Blood and Marrow Transplant...
Novartis

Unknown

Association of FcγRIIIA Polymorphism and THPO Expression With Response to Eltrombopag in Refractory ITP Patients

Immune Thrombocytopenic Purpura (ITP)

Pakistan
General Hospital of Ningxia Medical University

Not yet recruiting

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension on Maternal Hemodynamics

Outcome
Aga Khan University
Medical Research Council, Pakistan

Completed

Inhaled Prostacyclin for Adult Respiratory Distress Syndrome (ARDS) and Pulmonary Hypertension

Pulmonary Hypertension | Adult Respiratory Distress Syndrome
Yonsei University

Active, not recruiting

Effect of Mirabegron on Bladder Compliance

Patients With Low Bladder Compliance of 20ml/H2O or Less Despite Taking Anticholinergics

Korea, Republic of
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute

Recruiting

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes (PRECIDENTD)

Type2Diabetes | ASCVD

United States
King's College London

Recruiting

Glucagon-like Peptide 1 (GLP1) Receptor Agonists and Mental Health

Obesity | Diabetes Mellitus | Mental Health Issue

United Kingdom
Azienda Ospedaliero-Universitaria Consorziale Policlinico...

Completed

Efficacy of Glucagon-like Peptide-1 Receptor Agonists According to Type 2 Diabetes Subtypes

Diabetes Mellitus, Type 2

Italy
Jose Seijas Amigo

Completed

SEMAGLUTIDE VERSUS GLP-1 RECEPTOR AGONISTS. EFFECTIVENESS , SAFETY AND QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS 2. OBSERVATIONAL, PROSPECTIVE AND MULTICENTER STUDY. SEVERAL STUDY. (SEVERAL)

Quality of Life | Diabetes Mellitus, Type 2 | Weight Loss | Safety Issues

Spain
General Hospital of Ningxia Medical University

Not yet recruiting

90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment

Adverse Effect
Pär Johansson

Completed

Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA)

Cardiac Arrest

Denmark
Wake Forest University Health Sciences
Astellas Pharma US, Inc.

Terminated

Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR)

Coronary Artery Disease | Asthma | Chronic Obstructive Pulmonary Disease (COPD) | Angina

United States
AstraZeneca

Completed

ZAP, US. Zomig for Appropriate for Primary Care

Migraine

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