Search clinical trials for: Prostaglandin Antagonists

Total 33011 results

Actelion

Completed

REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtension (REPAIR)

Pulmonary Arterial Hypertension

United States, Israel, France, Netherlands, Malaysia, Germany, Australia, United Kingdom, Hong Kong, Italy, Russian Federation, Singapore
Takeda

Completed

A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids

Uterine Fibroids

Japan
AstraZeneca

Terminated

Oral Mucosal Absorption Study of Bicalutamide New Formulation

Healthy
Kremers Urban Development Company
Watson Pharmaceuticals

Completed

Bioequivalence Study of Bicalutamide 50 mg Tablet and Casodex® 50 mg Tablet in Healthy Subjects Under Fed Conditions

Healthy

Canada
Teva Pharmaceuticals USA

Completed

Study of Bicalutamide 1 x 50 mg Tablet in Healthy Subjects Under Fasting Conditions

Healthy

Canada
AstraZeneca

No longer available

Casodex 150-mg Compassionate Use Trial for Subjects With Prostate Cancer

Adenocarcinoma of the Prostate
Centre hospitalier de l'Université de Montréal...
Quebec Researchnetwork on aging

Recruiting

Mirtazapine for Chronic Insomnia in Older Adults (MIRAGE)

Chronic Insomnia

Canada
Northwestern University

Recruiting

Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer

Metastatic Prostate Carcinoma | Recurrent Prostate Carcinoma | Stage IV Prostate Cancer | Hormone-Refractory Prostate Cancer | Castration-Resistant Prostatic Cancer

United States
Ain Shams University

Completed

Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache

Headache

Egypt
Hospices Civils de Lyon

Terminated

Mirtazapine in Cancer-related Poly-symptomatology (MIR-P)

Neoplasms | Cancer | Neoplasm Metastasis

France
Catherine Naseef Hunter

Completed

Mirtazapine for Treatment of Cancer Associated Anorexia-cachexia (MCACS100)

Advanced Cancer | Cancer Associated Anorexia - Cachexia

Egypt
Actavis Inc.

Completed

A Relative Bioavailability Study of Mirtazapine 15 mg Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Mirtazapine 15 mg Tablets Under Non-fasting Conditions

Healthy

United States
Treadwell Therapeutics, Inc

Recruiting

CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer

Breast Cancer | Advanced Solid Tumor

United States
Kyoto Breast Cancer Research Network

Terminated

Anti PD-L1 Antibody + Anti CTLA-4 Antibody in Combination With Hormone Therapy in Patients With Hormone Receptor Positive HER2-negative Recurrent or Metastatic Breast Cancer

Breast Cancer

Japan
Novartis Pharmaceuticals

Completed

An Open Label Multi-center Extension Study to Evaluate Long-term Safety/ Tolerability of Dovitinib in Patients With Solid Tumors Who Continue to Receive Treatment With Dovitinib (TKI258) in Novartis-sponsored Single Agent Dovitinib Studies Which Fulfilled the Requirements for the Primary Objective

Solid Tumors

Austria, Belgium, United States, Italy, Denmark, Spain, Japan
University of Wisconsin, Madison
AstraZeneca; University of Pittsburgh

Withdrawn

Trial of ZD6474 and Faslodex in Non-Small Cell Lung Cancer

Carcinoma, Non Small Cell Lung
Kinnov Therapeutics

Not yet recruiting

A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine

Alcohol Use Disorder
UCB S.A. - Pharma Sector

Completed

Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects

Rhinitis, Allergic, Seasonal

Canada
NeuroRx, Inc.
Target Health Inc.

Active, not recruiting

NRX-101 for Maintenance of Remission From Severe Bipolar Depression in Patients With Suicidal Ideation (SBD-ASIB)

Suicidal Ideation | Bipolar Depression

United States
Sumitomo Pharma Co., Ltd.

Completed

A Phase III Study of SM-13496 in Patients With Bipolar I Depression.

Bipolar Depression

Lithuania, Malaysia, Russian Federation, Slovakia, Ukraine, Japan, Philippines, Taiwan
Sunovion

Completed

A Study Evaluating Lurasidone for The Treatment of Schizophrenia or Schizoaffective Disorder in Subjects Switched From Other Antipsychotic Agents (SWITCHCore)

Schizophrenia | Schizoaffective Disorder

United States
Sunovion

Completed

Rifampin Drug-Drug Interaction Study With Lurasidone HCl

Male, Healthy Normal Subjects

United States
Sunovion

Completed

Digoxin Drug-Drug Interaction With Lurasidone HCl

Schizophrenia

United States
University of Saskatchewan

Completed

Airway Responses to Montelukast and Desloratadine.

Asthma

Canada
OnKure, Inc.

Recruiting

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer (PIKture-01)

Breast Cancer | Advanced Cancer

United States
Organon and Co

Completed

Evaluation of Desloratadine When Used in Patients With Either Allergic Rhinitis or Chronic Idiopathic Urticaria (Aerius)

Rhinitis | Urticaria
Novartis Pharmaceuticals

Terminated

A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi (BELLE-3)

Metastatic Breast Cancer

United States, Germany, Belgium, Canada, France, Italy, Spain, United Kingdom, Austria, Argentina, Sweden, Hungary, Korea, Republic of, Lebanon, Bulgaria, Greece, Thailand, Netherlands, Colombia, Norway, Finland, Poland
Merck Sharp & Dohme LLC

Not yet recruiting

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) and Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

Non-small Cell Lung Cancer (NSCLC)
Ain Shams University

Recruiting

Mirtazapine Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting

Post Operative Nausea and Vomiting

Egypt
University of Wisconsin, Madison

Completed

Treatment of Symptoms After Stent Placement for Urinary Tract Obstruction

Ureteral Obstruction

United States
Astellas Pharma Inc

Completed

A Study With Combination Treatment (Tamsulosin Hydrochloride and Solifenacin Succinate) in Male Patients With LUTS/BPH (SATURN)

Lower Urinary Tract Symptoms | Prostatic Hyperplasia

France, Poland, Germany, Spain, Finland, Netherlands, Russian Federation, Czech Republic, Hungary, Norway, Denmark, Slovakia, Sweden, Austria, Portugal, United Kingdom
Cheng-Hsin General Hospital

Completed

Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy

Heart Failure | Hypotension

Taiwan
Organon and Co

Completed

An Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Chronic Urticaria (MK-4117-201)

Urticaria
Eagle Pharmaceuticals, Inc.

Completed

Study to Evaluate the Safety, Tolerability, and PK of Fulvestrant After IM Administration

Pharmacokinetics

United States
AstraZeneca

Completed

Study to Compare the Effects of AZD9496 vs Fulvestrant in Breast Cancer. (D6090C00002)

Postmenopausal Women With ER+ HER2- Primary Breast Cancer

Germany, United Kingdom
Tigris Pharmaceuticals

Terminated

Study of AFP464 +/- Faslodex in ER + Breast Cancer

Breast Neoplasm

United States
Actelion

Completed

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease (SERENADE)

Heart Failure With Preserved Ejection Fraction

United States, Spain, United Kingdom, Poland, Germany, Israel, Austria, Czechia, Russian Federation, Denmark, Bulgaria, Hungary, France, Argentina, Brazil, Romania, Sweden
Viramal Limited

Completed

Study to Determine Intraperitoneal,Tissue, Serum Concentrations of VML-0501 Following Five Days of Daily Vaginal Single Dose of VML-0501 (100 mg Danazol), in Comparison to Oral Danazol Capsules Daily 600 mg), in Women With Signs and Symptoms of Endometriosis Undergoing Laparoscopy

Endometriosis

Italy
Actelion

Completed

Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH

Pulmonary Arterial Hypertension

Spain, France, Italy
Shanghai Mental Health Center

Completed

a Pilot Study of Pramipexole to Treat Extrapyramidal Symptoms Induced by Antipsychotics

Extrapyramidal Syndrome

China
Centre de Recherche de l'Institut Universitaire...

Completed

Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVI (ARTE)

Myocardial Infarction | Stroke | Bleeding | Aortic Valve Disease

Canada, Chile, Spain
National Institute of Mental Health (NIMH)

Terminated

Treatment of Menstrually Related Disorders With Continuous v. Interrupted Oral Contraceptives

Depression | Premenstrual Dysphoric Disorder | Premenstrual Syndrome | PMS | PMDD

United States
University of Southern California

Recruiting

Danazol for Treatment of Cytopenias in Patients With Cirrhosis

Cirrhosis, Liver | Cytopenia

United States
Alessa Therapeutics Inc.

Completed

A Study to Establish the Feasibility of Biolen for the Local Delivery of Bicalutamide in Patients With Prostate Cancer (Biolen-PC)

Lower Urinary Tract Symptoms | Prostate Adenocarcinoma

United States, Australia, New Zealand
Actelion

Completed

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension (SERAPHIN OL)

Pulmonary Arterial Hypertension

United States, United Kingdom, Taiwan, Finland, Canada, Belarus, Belgium, Argentina, Australia, China, Colombia, Croatia, Germany, Hong Kong, India, Israel, Italy, Malaysia, Netherlands, Poland, Russian Federation, South Africa, Tha... and more
Fudan University

Terminated

Bicalutamide as A Treatment in AR-positive Metastatic Triple-Negative Breast Cancer (mTNBC) Patients

Breast Cancer

China
Teva Pharmaceuticals USA

Completed

Study of Bicalutamide 1 x 50 mg Tablet in Healthy Subjects Under Fed Conditions

Healthy

Canada
AstraZeneca
Scandinavian Prostate Cancer Group

Completed

Casodex vs Placebo in Non-Metastatic Early Prostate Cancer (SPCG6)

Non-Metastatic Prostate Cancer

Sweden, Finland, Norway, Denmark
Jeil Pharmaceutical Co., Ltd.

Completed

The PK Study of the JLP-1207 and Solifenacin/Tamsulosin in Healthy Male Volunteers.

Overactive Bladder | Benign Prostatic Hyperplasia | LUTS(Lower Urinary Tract Symptoms)

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