Search clinical trials for: Prostaglandin Antagonists

Total 32996 results

Merck Sharp & Dohme LLC

Completed

Dose-Finding Safety and Efficacy Trial of Org 50081 (Esmirtazapine) in the Treatment of Vasomotor Symptoms (177001/P06472/MK-8265-013)

Vasomotor Symptoms | Menopause | Postmenopausal Symptoms
Merck Sharp & Dohme LLC

Completed

Dose-Finding Safety and Efficacy Trial of Org50081 (Esmirtazapine) in the Treatment of Vasomotor Symptoms (46101/P06459/MK-8265-012)

Vasomotor Symptoms | Menopause
Kyoto University
National Center of Neurology and Psychiatry, Japan

Completed

Strategic Use of New Generation Antidepressants for Depression (SUN(^_^)D)

Unipolar Major Depressive Episode

Japan
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Effect of Single and Multiple Doses Org 50081 and a Single Dose of Zopiclone on Next-day Driving Ability and Psychomotor Performance in Healthy Volunteers. (P05794) (COMPLETED)

Mental Disorders | Sleep Initiation and Maintenance Disorders
University of Colorado, Denver
National Institute on Aging (NIA)

Not yet recruiting

Cardiometabolic Consequences of the Loss of Ovarian Function (LILAC)

Menopause | Aging | Adiposity | Estrogen Deficiency

United States
Nanjing Chia-tai Tianqing Pharmaceutical

Recruiting

A Phase Ib/Ⅱ Study of NTQ1062 in Combination With Fulvestrant in Patients With Advanced HR Positive /HER-2 Negative Breast Cancer

HR Positive/HER-2 Negative Breast Cancer

China
Scorpion Therapeutics, Inc.

Recruiting

First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Breast Cancer | Gynecologic Cancer | HNSCC | Solid Tumors, Adult

United States, Spain, France, Italy
Liaoning Tumor Hospital & Institute

Not yet recruiting

Clinical Study of Fulvestrant Combined With Chidamide in the Treatment of Hormone Receptor-positive Advanced Breast Cancer Resistant to CDK4/6 Inhibitors

Breast Cancer
The First Affiliated Hospital of Zhengzhou University

Recruiting

An Exploratory Study of Surufatinib Combined With Chidamide and Fulvestrant in HR Positive Unresectable Metastatic Breast Cancer

Breast Cancer | Breast Cancer Female

China
Novartis Pharmaceuticals

Recruiting

Study of PIK3CA Mutations and Effectiveness and Tolerability Outcomes of Alpelisib in Real-world (SPEAR)

Breast Cancer

India
Sun Yat-sen University

Recruiting

Fulvestrant Plus Anlotinib in HR(+)/HER2(-) Metastatic Breast Cancer With FGFR Mutation

Breast Cancer

China
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) Combined With Fulvestrant in Women With Hormone Receptor Positive HER2 Negative Breast Cancer (MONARCH 2)

Breast Neoplasms

United States, Spain, Germany, Taiwan, Canada, Japan, Australia, Belgium, Denmark, France, Finland, Mexico, Italy, Korea, Republic of, Poland, Russian Federation, Switzerland, Puerto Rico, Romania, Greece
Novartis Pharmaceuticals

Active, not recruiting

Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant in Japanese Men and Postmenopausal Women With Advanced Breast Cancer

Advanced Breast Cancer

Japan
Pfizer

Withdrawn

Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.

Breast Cancer | Ovarian Cancer | Non-small Cell Lung Cancer (NSCLC) | Solid Tumors | Liposarcoma | Endometrial
Massachusetts General Hospital
Exelixis

Active, not recruiting

Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast Cancer

Breast Cancer

United States
UNICANCER

Terminated

SAFIR-PI3K A Phase II Randomized Maintenance Trial Comparing Alpelisib and Fulvestrant Versus Chemotherapy in PIK3CA Mutated Advanced Breast Cancer (SAFIR-PI3K)

Breast Cancer, PI3K, Alpelisib

France
Genentech, Inc.

Terminated

A Study of GDC-0810 Versus Fulvestrant in Postmenopausal Women With Advanced or Metastatic Breast Cancer Resistant to Aromatase Inhibitor (AI) Therapy (HydranGea)

Breast Cancer

United States, Spain, United Kingdom, Germany, Korea, Republic of, Australia
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP-3)

Healthy Males

United States
Chongqing Medical University
Fuling Central Hospital of Chongqing City

Unknown

Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis (ESTTFCP)

Prostatitis

China
Assistance Publique - Hôpitaux de Paris

Unknown

The RATIO: Registry of Infections and Lymphoma in Patients Treated With TNF-a Antagonists

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Ankylosing Spondylitis

France
University of Oklahoma

Not yet recruiting

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Androgen Deprivation Therapy | Locally Advanced Prostate Cancer

United States
Icahn School of Medicine at Mount Sinai

Recruiting

Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

Breast Cancer | Metastasis

United States
University of California, Los Angeles
American Heart Association; Janssen, LP

Completed

Endothelin-1 and Cardiac Allograft Vasculopathy (CAV)

Cardiac Allograft Vasculopathy

United States
Icahn School of Medicine at Mount Sinai
Beth Israel Medical Center

Terminated

Safety Study of Danazol With Plasma Exchange and Steroids for the Treatment of Thrombotic Thrombocytopenic Purpura (TTP) (TTP)

Thrombotic Thrombocytopenic Purpura

United States
Seoul National University Hospital
Kyowa Kirin Korea Co., Ltd.

Unknown

Phase II Trial of Romiplostim With Danazol in Patients With Eltrombopag-resistant Immune Thrombocytopenia

Immune Thrombocytopenia
University of L'Aquila

Completed

Survival Outcomes and Tumor Molecular Profile Following Bicalutamide Neoadjuvant Therapy

Prostate Cancer

Italy
University Hospital Birmingham
Royal Free Hospital NHS Foundation Trust; University of Edinburgh; University...

Unknown

Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD (SPIRO-CKD)

Renal Insufficiency, Chronic | Cardio-Renal Syndrome

United Kingdom
Assiut University

Unknown

Fulvestrant in Metastatic Breast Cancer

Metastatic Breast Cancer
Sumitomo Pharma (Suzhou) Co., Ltd.

Completed

The Safety and Efficacy of Lurasidone With Different Initiation Dose in Chinese Acute Phase Patients With Schizophrenia

Schizophrenia

China
Sumitomo Pharma (Suzhou) Co., Ltd.
Sunovion

Terminated

A Study of Lurasidone Compared With Placebo for the Treatment of Bipolar I Depression

Bipolar I Depression

China
Sumitomo Pharma Co., Ltd.

Completed

A Long-Term Study of SM-13496 in Patients With Bipolar I Disorder.

Bipolar I Disorder

Japan, Lithuania, Malaysia, Philippines, Russian Federation, Slovakia, Taiwan, Ukraine
Sunovion

Completed

A Study to Determine the Maximum Tolerated Dose of an Investigational Drug in Subjects With Schizophrenia

Schizophrenia

United States
Sumitomo Pharma (Suzhou) Co., Ltd.
Xuhui Central Hospital, Shanghai

Completed

Pharmacokinetic Study of Lurasidone After Multiple Oral Administration in Healthy Human Subjects

Schizophrenia

China
Sunovion

Completed

Lurasidone Pediatric Bipolar Study (Illuminate)

Bipolar I Depression

United States, Korea, Republic of, Bulgaria, Poland, Mexico, Puerto Rico, Colombia, Hungary, France, Philippines, Ukraine
Sunovion

Completed

Lurasidone Pediatric Pharmacokinetics Study

Schizophrenia | Autism

United States
Northwestern University
Sunovion

Completed

High Dose Lurasidone for Patients With Treatment Resistant Schizophrenia (HDL)

Schizophrenia

United States
Sunovion

Completed

A Study of Subjects Switched to Lurasidone for the Treatment of Schizophrenia or Schizoaffective Disorder (Switch Ext)

Schizophrenia | Schizoaffective Disorder

United States
Sunovion

Completed

Lurasidone HCl: A Phase 3 Study of Patients With Acute Schizophrenia

Schizophrenia

United States, Malaysia, Ukraine, India, Romania, Russian Federation, France
Sunovion

Completed

RI-AME Study OF [ISOTHIAZOLYL-3-14C]-LURASIDONE

Pharmacokinetics | Metabolism

United States
Sunovion

Completed

Lurasidone HCI - A 6-week Phase 3 Study of Patients With Bipolar I Depression (PREVAIL3)

Bipolar Depression

United States, Canada, Colombia, Czech Republic, India, Japan, Lithuania, Peru, Slovakia, Ukraine
Ain Shams University

Completed

Emergence Agitation After Nasal Surgery: a Randomized Controlled Comparison Between Melatonin and Mirtazapine

Agitation

Egypt
Sun Yat-sen University

Unknown

Efficacy and Safety Analyses of Mirtazapine in NSCLC Patients With Depression

Depression | Carcinoma, Non-Small-Cell Lung

China
The University of Queensland

Recruiting

The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis

Pulmonary Fibrosis | Dyskeratosis Congenita | Telomere Shortening | Telomere Disease

Australia
Takeda

Completed

A Study of TAK-385 in Hormone Treatment-naïve Participants With Prostate Cancer

Hormone Treatment-naïve Participants With Prostate Cancer

Japan
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Danazol for Genetic Bone Marrow and Lung Disorders

Aplastic Anemia

United States
Actelion

Withdrawn

Safety and Tolerability Study of Macitentan in Patients With Idiopathic Pulmonary Fibrosis (MUSIC OL)

Idiopathic Pulmonary Fibrosis
University of Athens

Unknown

Postoperative Pain and Angiotensin II Receptor Antagonists (PP&ARA)

Hypertension

Greece
Myovant Sciences GmbH

Completed

Study of Relugolix Alone and Relugolix Combined With Hormonal Add-Back Therapy in Healthy Premenopausal Female Participants

Healthy

United States
AstraZeneca

Completed

Treatment Protocol to Monitor the Safety of a 200 mg Dose of Bicalutamide in Patients With Advanced Prostate Cancer

Prostate Cancer

United States
Carrick Therapeutics Limited

Completed

Modular Study to Evaluate CT7001 Alone in Cancer Patients With Advanced Malignancies

Advanced Solid Malignancies

United States, United Kingdom

Search clinical trials for: Prostaglandin Antagonists

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