Search clinical trials for: Proteolytic enzymes

Total 47751 results

Monica E. Kleinman
Schering-Plough

Completed

Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria

Progeria | Hutchinson-Gilford Syndrome

United States
Bristol-Myers Squibb

Completed

A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet

Healthy Volunteers

United States
American Regent, Inc.

Completed

Safety, Tolerability, and Pharmacokinetic Study of Methylene Blue Following a 1 mg/kg Intravenous Dose in Healthy Adults

Methemoglobinemia | Congenital Methemoglobinemia
Loyola University

Withdrawn

Actinic Cheilitis Pre-Treated With DNA Repair Enzyme Cream

Actinic Cheilitis

United States
Millennium Pharmaceuticals, Inc.

Completed

Dose Escalation Study of TAK-117 (MLN1117) in Subjects With Advanced Cancer

Metastatic Solid Tumors

United States, Spain, United Kingdom
Agios Pharmaceuticals, Inc.

Completed

Food Effect Study of AG120 in Healthy Subjects

Healthy

United States
Umeå University
European Union

Terminated

Insecticidal School Uniforms for Dengue Prevention in Thailand (DengueTools)

Dengue

Thailand
ILEX Oncology Services, Incorporated

Completed

Marimastat in Treating Patients With Stage III Non-small Cell Lung Cancer

Lung Cancer

United States, Canada
M.D. Anderson Cancer Center
Gemin X

Terminated

Obatoclax for Systemic Mastocytosis

Leukemia | Systemic Mastocytosis

United States
Brigham and Women's Hospital
Eli Lilly and Company

Completed

Signaling Mechanisms and Vascular Function in Diabetes Mellitus

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus
Sumitomo Pharma Co., Ltd.

Completed

Safety and Efficacy of AS-3201 in the Treatment of Diabetic Sensorimotor Polyneuropathy

Diabetic Neuropathy

Canada
National University of Malaysia

Completed

Efficacy of Natural Enzymes Mouthwash: a Randomised Controlled Trial

Xerostomia | Dry Mouth

Malaysia
Forest Hills Lab

Not yet recruiting

Study to Evaluate the Safety, Tolerability, Efficacy, and PK of FHL-301 in Parkinson's Disease Patients.

Parkinson Disease
Tanta University

Recruiting

Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

Spontaneous Bacterial Peritonitis

Egypt
Chloe Atreya, MD, PhD
Merck Sharp & Dohme LLC; MedPacto, Inc.

Recruiting

Preoperative Immunotherapy (Pembrolizumab) for Patients With Colorectal Cancer and Resectable Hepatic Metastases

Metastatic Malignant Neoplasm in the Liver | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

United States
Tel-Aviv Sourasky Medical Center

Recruiting

Evaluation and Management of Cardio Toxicity in Oncologic Patients

Heart Failure

Israel
McGill University
Weizmann Institute of Science; Apotex Inc.

Completed

Enoxacin for Amyotrophic Lateral Sclerosis (ALS) (REALS-1)

Amyotrophic Lateral Sclerosis

Canada
University Hospital, Ghent
Universitair Ziekenhuis Brussel

Completed

Pharmacokinetics of Ciprofloxacin in Pediatric Patients

Urinary Tract Infection | Pyelonephritis

Belgium
University of Nebraska
National Cancer Institute (NCI)

Withdrawn

Talabostat in Treating Patients With Metastatic Kidney Cancer

Kidney Cancer
Oxford University Clinical Research Unit, Vietnam
University of Liverpool; Number 2 Children's Hospital, Ho Chi Minh City

Completed

Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery (CIPAZ)

Diarrhea | Shigellosis | Dysentery, Shigella

Vietnam
Bayer

Completed

Special Drug Use Investigation of Ciproxan Injection in Pediatrics

Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax

Japan
Mayo Clinic
National Cancer Institute (NCI)

Completed

Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancer

Small Cell Lung Cancer | Non-small Cell Lung Cancer | Dyspnea

United States
Mario Negri Institute for Pharmacological Research
Agenzia Italiana del Farmaco

Completed

Preventing Microalbuminuria in Type 2 Diabetes (VARIETY)

Diabetes

Italy
Elusys Therapeutics

Completed

Safety, Tolerability and PK of Intravenous (IV) ETI-204 Alone and in Presence of Ciprofloxacin in Adult Volunteers

Inhalational Anthrax

United States
Unity Health Toronto
University of Toronto

Completed

A Pilot Study of Norfloxacin for Hepatopulmonary Syndrome

Hepatopulmonary Syndrome

Canada
CPL Associates
Sanofi

Withdrawn

Outpatient Registry Trial of Respiratory Tract Infections in Adults

Pneumonia, Bacterial | Bronchitis, Chronic

United States
Eurofarma Laboratorios S.A.

Withdrawn

Comparison in the Treatment of Acute Cystitis Using Cephalosporin and Norfloxacin (CECI) (CECI)

Cystitis
University Of Nigeria Teaching Hospital

Completed

The Effect and Safety of Lisinopril in Non-hypertensive Men With Infertility From Low Sperm Count

Oligospermia

Nigeria
Bayer

Completed

Cipro Inhaler for Cystic Fibrosis Children Ages 6-12

Pseudomonas Infection

United States
Hvidovre University Hospital

Completed

Treatment of Ulcerative Colitis With Ciprofloxacin and E. Coli Nissle

Ulcerative Colitis

Denmark
Korean College of Helicobacter and Upper Gastrointestinal...

Unknown

Clinical Study to Evaluate the Efficacy and the Safety of Eradication Therapy for Helicobacter Pylori in Functional Dyspepsia

Functional Dyspepsia | Helicobacter Pylori Infection

Korea, Republic of
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of Rifaximin vs Norfloxacin for Secondary Prophylaxis of SBP (NORRIF Trial)

Spontaneous Bacterial Peritonitis

India
University of Washington

Recruiting

SpeeDx Ciprofloxacin gyrA Assay for N. Gonorrhoeae Gonococcal Infection

Neisseria Gonorrhoeae Infection

United States
Sunnybrook Health Sciences Centre
Alzheimer's Drug Discovery Foundation; Weston Brain Institute

Recruiting

Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients (SARTAN-AD)

Alzheimer's Disease

Canada
University of Karachi
Merck (Pvt.) Limited, Pakistan; Center for Bioequivalence Studies and Clinical...

Completed

Bioequivalence Study of Klaribact 125mg/5ml, Suspension (BE)

Healthy

Pakistan
Mario Negri Institute for Pharmacological Research

Active, not recruiting

Remission Clinic in Proteinuric Chronic Nephropathies

Chronic Kidney Disease

Italy
Zhongnan Hospital

Active, not recruiting

Effects of Metabolic Enzymes and Transporter Gene Polymorphisms on the Pharmacokinetics and Metabolism of Oral Abiraterone Acetate in Healthy Chinese Adults

Pharmacokinetic | Abiraterone Acetate | Plasma Concentration | Gene Polymorphism | Metabolic Analysis

China
Ospedali Riuniti di Foggia

Active, not recruiting

Rifaximin Versus Norfloxacin in Spontaneous Bacterial Peritonitis

Spontaneous Bacterial Peritonitis

Italy
Boehringer Ingelheim
Eli Lilly and Company

Completed

Empagliflozin and ACEi- Effects on Hyperfiltration: BETWEEN Study

Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Canada
Novo Nordisk A/S

Completed

A Trial Investigating the Influence of Oral Semaglutide on the Pharmacokinetics of Lisinopril and Warfarin in Healthy Subjects

Healthy | Diabetes

Germany
University of Chicago
National Cancer Institute (NCI)

Completed

Food Effect Study of Abiraterone Acetate for Treatment of Patients With Castration-Resistant Prostate Cancer

Castration-resistant Prostate Cancer | Stage IV Prostate Cancer

Singapore, United States
GlaxoSmithKline
Parexel

Completed

Bioequivalence Study Between GR37547 500 Milligrams (mg) Tablet Versus Ciprofloxacin 500 mg Tablet Reference Product in Healthy Adult Subjects

Infections, Bacterial

South Africa
Center for Supporting Hematology-Oncology Trials
Bayer

Completed

Comparing Ciprofloxacin (CPFX) With Cefepime (CFPM) in Febrile Neutropenic Patients With Hematologic Diseases

Febrile Neutropenia

Japan
OBS Pakistan

Unknown

Noroxin Efficacy and Safety Trial (NEST)

Urinary Tract Infections
Newcastle-upon-Tyne Hospitals NHS Trust
Northumbria Healthcare NHS Foundation Trust; North East Ambulance Service NHS...

Completed

Paramedic Initiated Lisinopril For Acute Stroke Treatment (PIL-FAST)

Stroke

United Kingdom
Aradigm Corporation

Completed

Safety and Efficacy Study of Ciprofloxacin for Inhalation in Patients With Non-Cystic Fibrosis Bronchiectasis "ORBIT-1"

Non-Cystic Fibrosis Bronchiectasis

United States, Germany, Canada, United Kingdom
Korea University
Kyungpook National University Hospital; Soon Chun Hyang University; Sungkyunkwan...

Completed

Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention

Adverse Reaction to Other Drugs and Medicines

Korea, Republic of
Lawson Health Research Institute
The Physicians' Services Incorporated Foundation

Terminated

Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI)

Urolithiasis

Canada
Panineeya Mahavidyalaya Institute of Dental Sciences...

Completed

Clarithromycin is an Adjunct to Scaling and Root Planing (CASRCMI)

Periodontitis
University of Washington

Completed

Cefpodoxime vs Ciprofloxacin for Acute Cystitis

Urinary Tract Infection

United States

Search clinical trials for: Proteolytic enzymes

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