Search clinical trials for: Proton Pump Inhibitors

Total 68234 results

Teva Pharmaceuticals USA

Completed

Lansoprazole 30 mg DR Capsule Replicate Food Study

Healthy

United States
Teva Pharmaceuticals USA

Completed

Lansoprazole 30 mg DR Capsule Fasting Replicate Sprinkle Study

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer
Nycomed

Completed

Study Evaluating Pantoprazole Sodium Enteric-Coated Spheroid Suspension In Infants With Presumed GERD

Gastroesophageal Reflux

Poland, Italy, United States, France, Australia, Switzerland, Belgium, Germany
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Omeprazole Magnesium 20 mg DR Capsules Under Fasting Conditions

Healthy

India
VA Greater Los Angeles Healthcare System
Eisai Inc.; PriCara, Unit of Ortho-McNeil, Inc.

Completed

Comparison of the Nighttime Effects of Two Different Drugs on Subjects With GERD

Gastroesophageal Reflux Disease

United States
AstraZeneca
UMC Utrecht

Completed

PPI Test in GP Patients

GERD

Netherlands
National Taiwan University Hospital

Unknown

The Role of CYP2C19 on the Eradication of H. Pylori Infection:Implication of PK/PD Relationships

Peptic Ulcer With H. Pylori Infection | Gastritis With H. Pylori Infection

Taiwan
Shandong University
Zibo Central Hospital; Peking University Care Luzhong Hospital; Taierzhuang District... and other collaborators

Recruiting

Bismuth Quadruple Therapy in Helicobacter Pylori Rescue Therapy of Different Tetracycline Doses and Frequencies.

Helicobacter Pylori Infection

China
Odense University Hospital

Not yet recruiting

Heterogeneously Hypofractionated Radiotherapy for Locally Advanced NSCLC (HERAN2)

Frailty | Non-small Cell Lung Cancer Stage III | Radiotherapy Side Effect
Yonsei University

Not yet recruiting

Efficacy of Fexuprazan for Prevention or Control of Gastritis Symptoms in Patients on Treatment With Systemic Steroids

Patients on Treatment With Systemic Steroids

Korea, Republic of
Afferent Pharmaceuticals, Inc.
Celerion

Completed

A Multiple-Dose Pharmacokinetics Study of Two Gefapixant (AF-219/MK-7264) Formulations

Healthy

United States
Agios Pharmaceuticals, Inc.

Completed

A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881

Healthy Volunteers

United States
Children's Hospital Srebrnjak
Belupo; University Hospital Center Sisters of Charity, Zagreb, Croatia

Completed

Omeprazole 20 mg in Patients With Laryngopharyngeal reﬂux and Comorbid Chronic Rhinosinusitis

Chronic Rhinosinusitis (Diagnosis) | Laryngopharyngeal Reflux
Aswan University Hospital

Unknown

Esomeprazole for the Prevention of Preeclampsia

Pre-Eclampsia

Egypt
Pfizer

Completed

A Study Of Glasdegib In Healthy Volunteers To Establish The Bioequivalence Of The Phase 2 Formulation To The ICH Formulation (B1371026)

Healthy Volunteers

United States
Mayo Clinic

Completed

Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation?

Inflammation | Barrett's Esophagus

United States
Chang Gung Memorial Hospital
TTY Biopharm

Unknown

Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbances

Sleep Disturbance | Gastroesophageal Reflux Disease | Heartburn

Taiwan
Il-Yang Pharm. Co., Ltd.

Completed

Efficacy/Safety Study as H. Pylori Eradication of Triple Therapy for 7 Days Treatment

Peptic Ulcer

Korea, Republic of
HK inno.N Corporation

Completed

Safety, Tolerability, PK, PD of Escalating Single and Multiple Oral Doses of CJ-12420 in Healthy Male Subjects

Healthy

Korea, Republic of
Takeda

Completed

Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Erosive Esophagitis

Erosive Esophagitis

Japan
AstraZeneca

Completed

Barrett's Esophagus - 315 - 3 Way Cross-Over

Barrett's Esophagus
AstraZeneca

Completed

A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive Esophagitis

Erosive Esophagitis
AstraZeneca

Completed

Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Comparison of the Remission Rates of Once Daily Treatment With Esomeprazole 20mg and Lansoprazole 15mg for 6 Months in Patients Whose EE Has Been Healed

Erosive Esophagitis
Onconic Therapeutics Inc.

Not yet recruiting

Clinical Trial to Evaluate the Efficacy and Safety of JP-1366 in Patients With Gastric Ulcer

Gastric Ulcer
Daewoong Pharmaceutical Co. LTD.

Completed

Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Erosive Gastroesophageal Reflux Disease (Phase 2, Therapeutic Exploratory Study)

Erosive Gastroesophageal Reflux Disease

Korea, Republic of
Torax Medical Incorporated

Completed

The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease (CALIBER)

GERD Gastroesophageal Reflux Disease

United States
Jordan Collaborating Cardiology Group
University of Jordan

Completed

The Effect of Proton Pump Inhibition on Palpitations

Arrhythmia

Jordan
Damascus Hospital

Withdrawn

Comparison of Low Against High Regimen of Proton Pump Inhibitors for Treatment of Acute Peptic Ulcer Bleeding

Peptic Ulcer Hemorrhage | Marginal Ulcer | Gastroduodenal Ulcer

Syrian Arab Republic
Eisai Co., Ltd.

Completed

Prognostic Study of Gastric MALT Lymphoma After Eradication of Helicobacter Pylori

Gastric Low-grade MALT Lymphoma With Helicobacter Pylori Positive

Japan
University of Utah

Terminated

Elucidation of Acid-Induced Pulmonary Inflammation

Asthma | Gastroesophageal Reflux

United States
Pfizer

Completed

PPI And Food Effect Study For PF-06463922 In Healthy Volunteers

Healthy

Belgium
Yuhan Corporation

Completed

Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(NERD)

Non-erosive Reflux Disease

Korea, Republic of
Yuhan Corporation

Completed

Food Effect on Pharmacokinetics of YH4808 in Healthy Male Subjects

Healthy

Korea, Republic of
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Pantoprazole in Children With GERD

Gastroesophageal Reflux

United States
AstraZeneca

Completed

Use Of Esomeprazole In Postoperative Bariatric Surgery Patients Users And Non-Users Of Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)

Postoperative Bariatric Surgery
PriCara, Unit of Ortho-McNeil, Inc.
Eisai Inc.

Completed

A Study of Rabeprazole and Pantoprazole on Stomach Acid and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease (GERD) and a History of Nighttime Heartburn

Gastroesophageal Reflux
Tampere University Hospital

Completed

The Effect of Esomeprazole and Fundoplication on Airways

Airway Responsiveness

Finland
The Christie NHS Foundation Trust
University of Manchester

Withdrawn

A Proof of Concept, Window Trial of the IMmunological Effects of AveLumab and Aspirin in Triple-Negative Breast Cancer (IMpALA)

Breast Cancer
The First Affiliated Hospital of Zhengzhou University

Unknown

A Study of Apatinib for Advanced Hepatocellular Carcinoma Patients After First-line Treatment Failure

Hepatocellular Carcinoma
Qingdao Municipal Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Apatinib in Combination With S-1 as First-Line Treatment in Patients With Advanced Gastric Cancer

Gastric Cancer
Mirati Therapeutics Inc.

Completed

A Study to Explore the Effect of Acid-reducing Agents

Healthy Adults

United States
Mayo Clinic

Recruiting

A Study to Evaluate the Impact of Lactobacillus Rhamnosus GG on Proton Pump Inhibitor-Induced Gut Dysbiosis

Healthy

United States
HK inno.N Corporation

Completed

Study to Confirm the Safety and Efficacy of Tegoprazan in Patients With Healed Erosive Reflux Disease

Erosive Reflux Disease

Korea, Republic of
Changhua Christian Hospital

Withdrawn

Oral vs Intravenous and Proton Pump Inhibitor (PPI）for Peptic Ulcer Bleeding (PUB)

Upper Gastrointestinal Bleeding
Yooyoung Pharmaceutical Co., Ltd.

Completed

PK/PD Clinical Trial of YYD601 in Healthy Adult Male

GERD

Korea, Republic of
Washington University School of Medicine
TAP Pharmaceutical Products Inc.; Doris Duke Charitable Foundation

Completed

A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion

Otitis Media With Effusion

United States
Neutec Ar-Ge San ve Tic A.Ş

Completed

The Effect of Dexrabeprazole on Intragastric and Intraesophageal Acidity

Gastroesophageal Reflux Disease (GERD)

Turkey
Vanderbilt University Medical Center

Completed

Do Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Predict Response to Treatment?

Gastroesophageal Reflux | Larynx Disease

United States
Singapore General Hospital

Completed

Optimal Dose of Omeprazole After Endoscopic Treatment of Bleeding Peptic Ulcers

Bleeding Peptic Ulcers Disease

Singapore
Eisai Inc.

Completed

Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)

United States

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