Search clinical trials for: Pulsatile IV insulin delivery (humalog, humulin, novolog)

Total 78 results

Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Withdrawn

Effects of Pulsatile Intravenous Insulin Delivery on Diabetic Neuropathy in pATIENTS (Pts) With Type 1 and Type 2 Diabetes

Diabetic Neuropathy

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Clinical Effects of Pulsatile Insulin Delivery on Cognitive Function- Phase 1

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Terminated

Effects of Pulsatile Insulin Delivery on Diabetic Neuropathy in Patients With Types 1 and 2 Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Terminated

Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy in Patients With Types 1 and 2 Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effect of Pulsatile IV Insulin on Circulating Risk Markers of Vascular and Metabolic Complications in Pts With Diabetes

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effect Pulsatile IV Insulin Therapy on the Quality of Life in Patients With Types 1 and 2 Diabetes

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effects of Pulsed Intravenous (IV) Insulin on Brittle and Uncontrolled Diabetes

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Withdrawn

Effects of Pulsatile Intravenous Insulin Delivery on Hypoglycemic Unawareness

Hypoglycemia

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effects of Pulsatile Intravenous (IV) Insulin on Wound Healing in Diabetics (wounds)

Diabetes | Wound Healing

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effects of Pulsatile Intravenous Insulin Therapy on Metabolic Integrity in Patients With Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
Global Infusion and Aspiration Systems, LLC

Unknown

Effects of Intensive Bolus Intravenous Insulin Delivery on Metabolic Integrity in Type 1 and Type 2 Diabetes

Diabetes Mellitus | Metabolic Integrity

United States
Eli Lilly and Company

Completed

Safety and Efficacy Study of Insulin Lispro Versus Insulin Aspart in Participants With Type 2 Diabetes on Insulin Pump Therapy

Type 2 Diabetes Mellitus

United States
Emory University

Completed

Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac Surgery (SITA-CABGDM)

Hyperglycemia

United States
Arkansas Children's Hospital Research Institute

Completed

Preservation of Pancreatic Beta Cell Function Through Insulin Pump Therapy (ktpump)

Diabetes Mellitus

United States
Emory University

Completed

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery (SITACABG NonDM)

Coronary Artery Disease

United States
Sansum Diabetes Research Institute
Eli Lilly and Company

Completed

Humalog® Mix50/50(tm) as a Treatment for Gestational Diabetes

Gestational Diabetes Mellitus
Joslin Diabetes Center
Novo Nordisk A/S

Terminated

Glycemic Stability of Insulin Aspart Versus Insulin Lispro in Insulin Pump Therapy

Type 1 Diabetes Mellitus

United States
Sansum Diabetes Research Institute
Sanofi

Completed

Comparator Trial Using Insulin Glulisine vs. Insulin Lispro for Treatment of Gestational Diabetes

Diabetes During Pregnancy

United States
University of Florida
Sanofi

Completed

Effect of Apidra Compared to Humalog in Decreasing Post-Prandial Hyperglycemia

Type 1 Diabetes

United States
Tulane University Health Sciences Center

Completed

Comparison of Insulins Aspart and Lispro in Insulin Pumps

Type 1 Diabetes Mellitus

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Safety and Efficacy of Insulin Degludec/Insulin Aspart in Patients With T1DM

Time in Range | HbA1c | Type 1 Diabetes Mellitus With Diabetic Gastroparesis

China
Massachusetts General Hospital
Boston University

Terminated

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas

Type 1 Diabetes Mellitus

United States
Vancouver General Hospital

Terminated

Insulin Therapy for Post-transplant Glucocorticoid Induced Hyperglycemia (PTHG)

Post-Transplant Glucocorticoid Induced Diabetes

Canada
Northwestern University

Terminated

Use of NPH Versus Basal Bolus Insulin for Steroid Induced Hyperglycemia

Insulin Resistance, Diabetes | Hyperglycemia Steroid-induced

United States
Halozyme Therapeutics

Completed

Randomized, Double Blind, 2 Way Crossover Study of CSII With, Versus Without, Pretreatment With Human Hyaluronidase

Type 1 Diabetes Mellitus

United States
Emory University

Withdrawn

Safety and Efficacy Study of Correcting Hyperglycemia in Patients With Diabetes Having Out-patient Surgery

Type 1 Diabetes | Type 2 Diabetes

United States
Massachusetts General Hospital

Completed

The Insulin-Only Bionic Pancreas Bridging Study- Pediatric Transitional Study

Type1 Diabetes Mellitus

United States
Becton, Dickinson and Company

Completed

Feasibility Study of the Effect of Intra-Dermal Insulin Injection on Blood Glucose Levels After Eating

Diabetes Mellitus, Type 1

Germany
Halozyme Therapeutics

Completed

A Pharmacokinetic and Glucodynamic Study of Subcutaneously Administered Insulin Analogs With rHuPH20 Compared to Insulin Analogs Alone

Healthy

United States
University of Roma La Sapienza

Completed

Humalog or Humulin for Intensive Insulin Therapy in Intensive Care Unit

Hyperglycemia

Italy
Halozyme Therapeutics

Completed

Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type II

United States
University of North Carolina, Chapel Hill
WakeMed Health and Hospitals

Completed

Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes (MIPOD)

Pregnancy | Non Insulin Dependent Diabetes

United States
State University of New York - Downstate Medical...

Terminated

Pilot: Insulin Sensitivity/Management in Hyperglycemic Patients in Perioperative Period ESRD/Non-ESRD

Diabetes Mellitus | End-Stage Renal Disease

United States
Yale University

Completed

Evaluation of Pharmacokinetics and Pharmacodynamic Properties of Rapid-Acting Insulin Analogs (PK/PD)

Diabetes Mellitus, Type I
Massachusetts General Hospital

Completed

The Insulin-Only Bionic Pancreas Bridging Study

Type1 Diabetes Mellitus

United States
Sanofi

Terminated

Evaluation of Virtual Versus Traditional Study Conducted in a Group Pilot Study in Adult Patients With Type 1 Diabetes Mellitus (eStudy)

Type 1 Diabetes Mellitus

United States, Canada
Halozyme Therapeutics

Completed

Pharmacokinetic (PK), Pharmacodynamic (PD), and Safety Study of Subcutaneously Administered Humalog® With and Without Recombinant Human Hyaluronidase (rHuPH20)and Humulin-R® With and Without rHuPH20

Diabetes Mellitus

United States
Halozyme Therapeutics

Completed

Liquid Meal Study With Insulin Lispro With/Without Recombinant Human Hyaluronidase PH20 (rHuPH20) and Regular Human Insulin With rHuPH20 to Compare Pharmacokinetics, Postprandial Glycemic Response, and Optimal Insulin Dose in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Emory University

Completed

Sitagliptin in Non-Diabetic Patients Undergoing General Surgery

Hyperglycemia

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Withdrawn

Effects of Pulsatile Intravenous Insulin Therapy on Cardiac Disease in Patients With Diabetes

Diabetes Mellitus, With Complications

United States
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; European Commission

Completed

Closed Loop Glucose Control in Intensive Care Unit (CLASSIC)

Stress Hyperglycaemia

United Kingdom
Halozyme Therapeutics

Completed

Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Halozyme Therapeutics

Completed

Dose-Ranging, Pharmacokinetic (PK), Glucodynamic (GD), Safety and Tolerability Study of Subcutaneously (SC) Administered Humulin R and Humalog With or Without rHuPH20

Healthy Volunteers

United States
Eli Lilly and Company

Terminated

Hospital Management of Hyperglycemia Study of Insulin Glargine Plus Insulin Lispro Versus Human Regular Insulin (HMH)

Hyperglycemia

United States
Halozyme Therapeutics

Completed

Pharmacokinetic and Glucodynamic Crossover Study of Subcutaneously (SC) Administered Insulin Lispro + Recombinant Human Hyaluronidase (rHuPH20) and Regular Human Insulin + rHuPH20 Compared to Insulin Lispro Alone

Diabetes Mellitus

United States
Halozyme Therapeutics

Completed

CONSISTENT 1: Metabolic and Safety Outcomes of Hylenex Recombinant (Hyaluronidase Human Injection) Preadministered at CSII Infusion Site in Participants With Type 1 Diabetes Mellitus (T1DM)

Type 1 Diabetes Mellitus

United States
Providence Health & Services

Withdrawn

Comparison Study of Insulin Glargine and NPH Insulin

Diabetes

United States
Halozyme Therapeutics

Completed

Safety Study of Subcutaneously-Injected Prandial INSULIN-PH20 NP Compared to Insulin Lispro Injection in Participants With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

United States
AstraZeneca

Completed

A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Albert Einstein College of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

New Onset Type 1 Diabetes: Role of Exenatide

Type 1 Diabetes

United States

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