Search clinical trials for: Purinergic P2X Receptor Antagonists

Total 9533 results

University of Nebraska
National Cancer Institute (NCI); Spectrum Pharmaceuticals, Inc

Completed

Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma

Peripheral T-cell Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Hepatosplenic T-cell Lymphoma

United States
Camillo Ricordi and Jay Skyler
Diabetes Research Institute Foundation

Withdrawn

Diabetes Islet Preservation Immune Treatment (DIPIT)

Autoimmune Diseases | Diabetes Mellitus | Hypoglycemia | Diabetes Mellitus, Type 1

United States
Organon and Co

Completed

Study of Mometasone Furoate/Formoterol Combination and Fluticasone/Salmeterol in Persistent Asthmatics Previously Treated With Inhaled Glucocorticosteroids (P04139)

Asthma
Organon and Co

Completed

Study of Inhaled Glucocorticosteroids/Long-Acting Bronchodilator Drugs in Subjects With Asthma That Have Been Taking Inhaled Glucocorticosteroids (Study P04705AM1)

Asthma
Laboratorios Poen

Completed

Difluprednate vs. a Prednisolone Acetate - Phenylephrine on Post-operative Inflammation Following Cataract Surgery.

Cataract

Argentina
Neutec Ar-Ge San ve Tic A.Ş

Completed

Tiotropium/Salmeterol/Fluticasone Fixed Dose Combination Tratment Via Discair vs Tiotropium Via Handihaler + Salmeterol/Fluticasone Via Diskus Free Combination Treatment

COPD

Turkey
GlaxoSmithKline

Completed

To Investigate the Gastrointestinal Behaviour of Two Triple Combination Products in Healthy Male Volunteers

Common Cold

United States
University of Manitoba

Completed

Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery

Pain, Postoperative | Brachial Plexus Block | Ambulatory Surgical Procedures | Shoulder Joint Disorder

Canada
Fayoum University Hospital

Completed

Dexamethasone Versus Dexmedetomidine

Postoperative Pain

Egypt
Boehringer Ingelheim

Terminated

Respimat® Inhaler vs a Metered Dose Inhaler Using Berodual® in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
LG Life Sciences

Completed

Safety and Pharmacokinetics Between Fixed-dose Combination VR 160/20 mg and Co-administration of Diovan® (Valsartan) Film-coated Tablet 160 mg and Crestor® (Rosuvastatin) 20 mg

Hypertension | Hyperlipidemia

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Completed

Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma

Lymphoma | Leukemia

United States
National Cancer Institute, Egypt

Recruiting

Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine in Bilevel Erector Spinae Plane Block in Breast Surgeries

Analgesia

Egypt
Boehringer Ingelheim

Completed

A Six-week Study Comparing the Efficacy and Safety of Tiotropium Plus Formoterol to Salmeterol Plus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Netherlands, Denmark, France, South Africa, Austria, Belgium, Sweden
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
University of Ioannina

Recruiting

Opioid-free Anaesthesia in Breast Cancer Surgery

Pain, Postoperative | Breast Cancer | Anesthesia | Pain, Chronic | Cancer Recurrence | Opioid Free Anaesthesia

Greece
Gelb, Arthur F., M.D.

Recruiting

Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Asthma

United States
South East Asia Research Collaboration with Hawaii
The Thai Red Cross AIDS Research Centre; Cooper Human Systems

Completed

Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV Infection

Acute HIV Infection

Thailand
Shanghai Biomabs Pharmaceutical Co., Ltd.

Completed

Anti-IgE Monoclonal Antibody Treatment in Patients With Allergic Asthma.

Asthma, Allergic

China
Capital Medical University

Unknown

A New System for GERD Diagnosis and Treatment (EAISMLP)

GERD
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Safety and Tolerability of MK-0517 in Healthy Subjects (MK-0517-012)

Postoperative Nausea and Vomiting | Chemotherapy-Induced Nausea and Vomiting
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

IMPAACT P1058A: Pharmacokinetic Effects of New Antiretroviral Drugs on Children, Adolescents and Young Adults

HIV Infections

United States, Puerto Rico
Mayo Clinic
National Center for Research Resources (NCRR)

Terminated

Epidural Clonidine for Lumbosacral Radiculopathy

Lumbar and Other Intervertebral Disc Disorders With Radiculopathy

United States
National Cancer Institute (NCI)

Active, not recruiting

Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer

Recurrent Breast Carcinoma | Invasive Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v6

United States, Puerto Rico
Jonsson Comprehensive Cancer Center
Novartis; Seagen Inc.

Recruiting

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC... and other conditions

United States
Fundacio Privada Mon Clinic Barcelona
GlaxoSmithKline

Recruiting

ANTES B+ Clinical Trial (ANTES B+)

Chronic Obstructive Pulmonary Disease

Spain
Poznan University of Medical Sciences

Recruiting

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery

Spinal Stenosis | Erector Spinae Plane Block | Spinal Fusion | Spine Disease

Poland
Ain Shams University

Completed

Comparison Between Adjuvants Added to Bupivacaine in Adductor Canal Block

Anesthesia

Egypt
Mansoura University

Active, not recruiting

Different Modalities of Analgesia in Open Heart Surgeries in Mansoura University

Coronary Artery Disease | Pain, Postoperative | Pain, Acute | Valve Disease, Heart

Egypt
Research in Real-Life Ltd
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Device Mixing in Asthma, a General Practice Research Database Study (EBsalbutamol)

Asthma

United Kingdom
OHSU Knight Cancer Institute

Terminated

Pegaspargase and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Leukemia

United States
University of Dundee
AstraZeneca; NHS Tayside

Completed

Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC Trial (MUSIC)

Chronic Obstructive Pulmonary Disease

United Kingdom
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Completed

A Bioequivalence Study Between Fluticasone and Salmeterol vs. SERETIDE DISKUS® in Healthy Volunteers With Charcoal Blockade

Bioequivalence

Greece
AstraZeneca

Completed

AMPLIFY - D6571C00001 Duaklir USA Phase III Study

Chronic Obstructive Pulmonary Disease

United States, Germany, Poland, Israel, Bulgaria, Czechia, Hungary, Spain, Ukraine, United Kingdom
University of Florida

Completed

Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)

Alpha-1 Antitrypsin Deficiency | Liver Fibrosis | AATD | AAT Deficiency

United States
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
Organon and Co

Completed

Study of Efficacy and Long-Term Safety of Mometasone Furoate in Combination With Formoterol Fumarate Versus Mometasone Furoate in Children (5 to 11 Years of Age) With Persistent Asthma (MK-0887A-087)

Asthma
University Hospital, Ghent

Completed

Multimodal Versus Opioid aNalgesia in carDiAc Surgery (MONDAY)

Postoperative Pain | Postoperative Delirium

Belgium
Assiut University

Unknown

Steroid Therapy in Acute Bronchiolitis A New Old Line of Therapy.

Bronchiolitis; Respiratory Syncytial Virus
Kirby Institute

Completed

MARCH Central Nervous System Substudy

HIV-1 Infection

Argentina, Thailand, United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent... and other conditions

United States
Jeremy Kearns

Terminated

Continuous Nerve Block Block vs Combination of Single Block Plus Intravenous Lidocaine for Postoperative Pain.

Postoperative Pain

United States
University of California, Davis

Completed

A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc Therapy

HIV Infections

United States
University of Rochester
Mae Stone Goode Foundation

Completed

Novel Topical Therapies for the Treatment of Genital Pain (Topicals)

Female Genital Diseases

United States
FLUIDDA nv

Completed

Compare the Effects of Seretide® Evohaler and a Generic Salmeterol/Fluticasone Hydrofluoroalkane (HFA) Pressurized Metered-dose Inhaler (pMDI) on Functional Respiratory Imaging Parameters in Asthmatic Patients

Asthma

Belgium
Hebei Medical University

Completed

The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure

Heart Failure

China
Freeman-Sheldon Research Group, Inc.

Withdrawn

Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions (FSS-EDICT I)

Craniofacial Abnormalities | Arthrogryposis

United States
Gelb, Arthur F., M.D.

Recruiting

Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma

Asthma

United States
GlaxoSmithKline

Completed

A Phase III Parallel Group Study, Comparing the Efficacy, Safety and Tolerability of the Fixed Dose Combination (FDC) of Fluticasone Furoate+Umeclidinium Bromide+Vilanterol (FF/UMEC/VI) With the FDC of FF/VI in Subjects With Inadequately Controlled Asthma

Asthma

Australia, United States, Argentina, Canada, Germany, Japan, Korea, Republic of, Romania, Russian Federation, Spain, South Africa, Netherlands, Poland, Italy, United Kingdom
Organon and Co

Completed

A Serious Asthma Outcome Study With Mometasone Furoate/Formoterol Versus Mometasone Furoate in Asthmatics 12 Years and Over (P06241) (SPIRO)

Asthma

Search clinical trials for: Purinergic P2X Receptor Antagonists

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