Search clinical trials for: Reverse Transcriptase Inhibitors

Total 66500 results

Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C223: TMC125 in HIV-1 Infected Subjects

HIV Infection
Pharmasset

Terminated

Efficacy and Safety of Clevudine Compared With Adefovir in Patients With Chronic Hepatitis Due to Hepatitis B Virus (QUASH2)

Hepatitis B | Chronic Hepatitis

United States, Canada, China, Argentina, Taiwan, Spain, Puerto Rico, Australia, Greece, Thailand, United Kingdom
Bristol-Myers Squibb

Completed

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

HIV-Associated Lipodystrophy Syndrome

Spain, Italy, United States, Canada, France, Mexico, United Kingdom, Poland, Germany
IRCCS Eugenio Medea
University of Rome Tor Vergata

Completed

Safety and Efficacy of Etravirine in Friedreich Ataxia Patients (FAEST1)

Friedreich Ataxia

Italy
Gilead Sciences

Completed

Observational Study of the Durability of Seroconversion Chronic HBV Patients Who Seroconverted in a Previous Gilead-Sponsored Study of ADV.

Hepatitis B
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-TiDP2-C187: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Interaction Between TMC125 and Two Antifungal Agents (Fluconazole and Voriconazole), All at Steady-state in Healthy Subjects.

Fungal Infection | HIV | AIDS
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C211: Trial of TMC125 in HIV-1 Infected Subjects Who Were in a Sponsor Selected TMC125 Trial

HIV Infection
Gilead Sciences

Terminated

Continued Access Study of Adefovir Dipivoxil (ADV) for Patients w/Chronic HBV Infection.

Hepatitis B
Boehringer Ingelheim

Completed

A Phase I Multiple Dose Pharmacokinetic Study of Nevirapine Extended Release (XR) in HIV-1 Infected Children.

HIV Infections

United States, Botswana, Germany, South Africa
University of Colorado, Denver

Completed

Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative Volunteers

Hepatitis C | HIV

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C216: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.

HIV
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

ARQ 501 in Subjects With Cancer

Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected Patients

HIV Infection | Hepatitis B

United States
Pharmacia and Upjohn

Completed

Prospective Open-Label Study of the Emergence of Drug Resistance in Patients Infected With HIV-1 Who Are Taking Oral U-87201E

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and Children

HIV Infections

United States, Brazil, South Africa
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C206: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.

HIV

United States, France, Argentina, Chile, Mexico, Costa Rica, Panama, Brazil, Puerto Rico, Thailand
GlaxoSmithKline

Completed

Drug Use Investigation for HEPSERA (Adefovir) Tablet

Hepatitis B
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

An Extension Study for Patients Previously Treated With ARQ 501

Cancer

United States
Pharmasset

Terminated

Efficacy and Safety of Clevudine Compared With Adefovir in Patients With HBeAg Positive Chronic Hepatitis Due to Hepatitis B Virus (QUASH 1)

Hepatitis B | Chronic Hepatitis

United States, Canada, Argentina, Taiwan, Spain, Puerto Rico, Australia, Greece, Thailand, United Kingdom, Brazil, China
Gilead Sciences

Completed

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

A Study on the Safety and Effectiveness of Adefovir Dipivoxil in Combination With Anti-HIV Therapy (HAART) in HIV-Positive Patients

HIV Infections

United States, United Kingdom, Germany, Canada, France
Yungjin Pharm. Co., Ltd.

Completed

Safety, Tolerability and Pharmacokinetic Study of MB12066 in Healthy Male Volunteers

Metabolic Syndrome

Korea, Republic of
Therapeutic Concepts
Abbott; Tibotec, Inc; BluKyne

Completed

A Pilot Study of Kaletra and Intelence Tablets in Naive Subjects (KALYINTE)

HIV Infections

United States
Bukwang Pharmaceutical

Terminated

A Study With Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

An Exploratory Biomarker Study of ARQ 501 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Tongji University
Interventional Radiology Research Group, Shanghai Radiology Society

Unknown

TACE and Adefovir Compared With Transarterial Chemoembolization (TACE) Alone for Hepatitis B Virus (HBV)-Related Unresectable Hepatocellular Carcinoma (HCC) (TACE)

Hepatocellular Carcinoma | Hepatitis B Virus

China
Abbott

Completed

Study of Lopinavir/Ritonavir Tablets Comparing Once-Daily Versus Twice-Daily Administration When Coadministered With Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral-Experienced Human Immunodeficiency Virus Type 1 Infected Subjects

Human Immunodeficiency Virus Infections

United States
John H. Stroger Hospital
University of Illinois at Chicago

Unknown

Characterization of Receptors in Non-functioning Pituitary Macroadenomas

Pituitary Tumor

United States
GlaxoSmithKline

Completed

Rosiglitazone-Metformin Combination Versus Metformin-Sulfonylurea Combination On Beta-Cell Function In Type 2 Diabetes

Type 2 Diabetes Mellitus
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Safety and Efficacy Study of ARQ 501 in Adult Patients With Leiomyosarcoma

Cancer

United States
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

A Study of ARQ 501 in Patients With Squamous Cell Carcinoma of the Head and Neck

Head and Neck Neoplasms | Carcinoma, Squamous Cell

United States
Gilead Sciences

Completed

Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations

HIV Infections

United States
Northwell Health
Cohen Children's Medical Center

Available

A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma

Neuroblastoma | Pheochromocytoma

United States
Thomas Jefferson University

Completed

Study Comparing the Safety of Switching From Lamivudine to Adefovir Dipivoxil Versus Overlapping Lamivudine and Adefovir Before Adefovir Dipivoxil Monotherapy in Patients With Chronic Hepatitis B

Chronic Hepatitis B
National Institute of Diabetes and Digestive and...
University of Michigan

Completed

Prevention of Recurrent Hepatitis B After Liver Transplantation

Hepatitis B | Hepatocellular Carcinoma | Cirrhosis | Acute Liver Failure

United States
Nanfang Hospital of Southern Medical University
Major Science and Technology Special Project of China Eleventh Five-year

Unknown

Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy (Dragon-Ex)

Chronic Hepatitis B | Inadequate Response | Nucleos(t)Ide Analogues Treatment

China
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

ARQ 501 in Combination With Docetaxel in Patients With Cancer

Carcinoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Adefovir Dipivoxil in HIV-Infected Children

HIV Infections

United States, Puerto Rico
GlaxoSmithKline

Completed

HEPSERA Post Marketing Surveillance (HEPSERA PMS)

Hepatitis B
Gilead Sciences

Completed

A Study of Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Been Treated With Anti-HIV Drugs

HIV Infections

United States
Astra USA

Completed

Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease

Gastrointestinal Diseases | HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Completed

Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome

HIV Infections | Cytomegalovirus Retinitis

United States
Yungjin Pharm. Co., Ltd.
KT&G Corporation

Completed

Safety, Tolerability and Pharmacokinetic Study of MB12066 in Healthy Volunteers

Obesity | Metabolic Syndrome
Gilead Sciences

Approved for marketing

An Open-Label Program of Adefovir Dipivoxil in the Treatment of Patients With Lamivudine-Resistant Chronic Hepatitis B With Limited Treatment Options

Chronic Hepatitis B
Gilead Sciences

Completed

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Bis-POM PMEA in HIV-Infected Patients

HIV Infections

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Biomarkers in Blood Samples From Older Breast Cancer Survivors

Breast Cancer

United States
Abbott

Completed

Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice Daily Administration, When Coadministered With Nucleoside Reverse Transcriptase Inhibitors in Antiretroviral Naive Human Immunodeficiency Virus Type 1 Infected Subjects

Human Immunodeficiency Virus Infections

United States, Australia, Belgium, Canada, Czech Republic, France, Germany, Greece, Ireland, Italy, Netherlands, Poland, Puerto Rico, Russian Federation, Singapore, Spain, Switzerland, Taiwan, United Kingdom
Merck Sharp & Dohme LLC

Completed

Single-Dose Islatravir in Moderate Hepatic Impairment (MK-8591-030)

Human Immunodeficiency Virus (HIV) Infection

United States

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