Search clinical trials for: Roflumilast Placebo

Total 53807 results

Spanish Research Center for Respiratory Diseases

Unknown

Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease (REVASC)

Chronic Obstructive Pulmonary Disease

Spain
Arcutis Biotherapeutics, Inc.

Completed

Safety and Efficacy of ARQ-151 Cream in Adolescents and Adults With Atopic Dermatitis

Atopic Dermatitis

United States, Canada
The University of Texas Health Science Center at...

Completed

Study of Roflumilast in Combination With Standard Chemotherapy for High-risk Diffuse Large B-cell Lymphoma

Lymphoma, B-Cell

United States
Dermatology Consulting Services, PLLC

Completed

Evaluation of the Safety and Efficacy of Topical Roflumilast Cream in the Treatment of Facial Papulopustular Rosacea

Rosacea

United States
University of Pittsburgh

Completed

Roflumilast on Markers of Bone Metabolism and Endothelial Function in COPD

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

Post Marketing Surveillance of Roflumilast in Korea

Chronic Obstructive Pulmonary Disease

Korea, Republic of
Fundación Pública Andaluza Progreso y Salud

Completed

Roflumilast Safety Administered Once a Day on Alternate Days for Two Weeks Compared to the Usual Dosage Once Daily (ROFLU2011)

Chronic Obstructive Pulmonary Disease (COPD)

Spain
University of Calgary

Withdrawn

Roflumilast TMS-EEG Plasticity

Synaptic Plasticity

Canada
AstraZeneca

Completed

Evaluation of Tolerability and Pharmacokinetics of Roflumilast, 250μg and 500μg, as add-on to Standard COPD Treatment to Treat Severe COPD (OPTIMIZE)

Chronic Obstructive Pulmonary Disease (COPD)

Slovakia
Arcutis Biotherapeutics, Inc.

Completed

Long-Term Safety of ARQ-151 Cream in Adult Subjects With Chronic Plaque Psoriasis

Plaque Psoriasis

United States, Canada
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Effect of Roflumilast on Quality of Life, Lung Function and Mucus Properties in Patients With Bronchiectasis

Bronchiectasis Adult

Brazil
Arcutis Biotherapeutics, Inc.

Completed

Long-Term Safety of ARQ-154 Foam in Subjects With Seborrheic Dermatitis

Seborrheic Dermatitis

United States
The University of Texas Health Science Center at...

Withdrawn

Clinical Trial of Roflumilast Added to Standard Chemoimmunotherapy

Lymphoma, B-Cell

United States
AstraZeneca
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 70 y) (APTA-2217-05)

Bronchial Asthma

Japan
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Roflumilast and Cognition (EEGrofl)

Dementia

Netherlands
Assiut University

Unknown

Assessment of Early Outcomes of Roflumilast in Patients With Non Cystic Fibrosis Bronchiectasis

Bronchiectasis
AstraZeneca
Mitsubishi Tanabe Pharma Corporation

Completed

Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 71 y) (APTA-2217-07)

Bronchial Asthma

Japan
AstraZeneca
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-06)

Chronic Obstructive Pulmonary Disease (COPD)

Japan
AstraZeneca
Mitsubishi Tanabe Pharma Corporation

Completed

Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-08)

Chronic Obstructive Pulmonary Disease (COPD)

Japan
Arcutis Biotherapeutics, Inc.

Completed

The Safety, Efficacy and Pharmacokinetics of ARQ-151 Cream in Subjects With Chronic Plaque Psoriasis (ARQ-151-201)

Plaque Psoriasis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-216)

Psoriasis | Plaque Psoriasis

United States, Canada, Dominican Republic
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast (ARQ-154) Foam 0.3% for the Management of Seborrheic Dermatitis (STRATUM)

Seborrheic Dermatitis

United States, Canada
Arcutis Biotherapeutics, Inc.

Completed

Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis (DERMIS-OLE)

Chronic Plaque Psoriasis

United States, Canada, Dominican Republic
Arcutis Biotherapeutics, Inc.

Completed

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Children With Plaque Psoriasis (ARQ-151-215)

Psoriasis | Plaque Psoriasis

United States, Canada, Dominican Republic
Chiesi Farmaceutici S.p.A.

Recruiting

A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR) (PILLAR)

Chronic Obstructive Pulmonary Disease

Bulgaria, United States, Argentina, Austria, Bosnia and Herzegovina, Chile, Croatia, Czechia, Estonia, Germany, Greece, Hungary, Israel, Latvia, Mexico, Netherlands, New Zealand, North Macedonia, Poland, Romania, Russian Federation and more
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals

Obesity

United States
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis (DERMIS-1)

Chronic Plaque Psoriasis

United States, Canada
AstraZeneca

Completed

Pharmacodynamic/Pharmacokinetic Interactions Between Oral Roflumilast and Inhaled Formoterol

Healthy

Germany
AstraZeneca

Terminated

Safety and Efficacy of Roflumilast and Pioglitazone in Treating Adults With Nonalcoholic SteatoHepatitis

Nonalcoholic Steatohapatitis

United States
AstraZeneca

Completed

Topical Roflumilast in Adults With Atopic Dermatitis

Atopic Dermatitis

Germany
The University of Hong Kong

Completed

Roflumilast in Non-CF Bronchiectasis Study

Non-cystic Fibrosis Bronchiectasis

Hong Kong
The University of Hong Kong

Recruiting

Roflumilast in Non-CF Bronchiectasis Study (2019)

Non-cystic Fibrosis Bronchiectasis

Hong Kong
National Institute on Aging (NIA)

Completed

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

Healthy Volunteers

United States
Maastricht University Medical Center

Recruiting

Cognitive Effects of Roflumilast in (a)MCI and Mild Dementia Patients (ROMEMA)

Mild Cognitive Impairment | Mild Dementia | Amnestic Mild Cognitive Disorder

Netherlands
AstraZeneca

Completed

Roflumilast Plus Montelukast in Adults With Severe Asthma

Asthma

Germany, South Africa, Hungary
Millennium Magnetic Technologies, LLC

Unknown

Pre-Clinical (Alzheimers) Diagnosis PCD = Optimum Outcomes OO (PCD=OOALZ)

Alzheimer Disease

United States
AstraZeneca

Completed

Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes

Type 2 Diabetes

United States
Johns Hopkins University
Patient-Centered Outcomes Research Institute

Recruiting

Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) (RELIANCE)

Chronic Bronchitis | Chronic Obstructive Pulmonary Disease Severe

United States
AstraZeneca

Completed

Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults

Alzheimer's Disease | Memory Impairment

United Kingdom
Takeda

Completed

Roflumilast Plus Antipsychotics Proof of Mechanism Study in Schizophrenia

Schizophrenia

United Kingdom
Cairo University

Completed

Roflumilast Versus Methotrexate in Psoriasis

Psoriasis

Egypt
Maastricht University
Netherlands Brain Foundation

Completed

Roflumilast to Treat Cognitive Sequela After Stroke (ROSTMEMA)

Cerebrovascular Disorders | Functional Recovery | Memory | Drug Intervention

Netherlands
University Medical Centre Ljubljana

Completed

PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome

Obesity | PCOS

Slovenia
GlaxoSmithKline

Completed

REQUIP (Ropinirole Hydrochloride) IR Long-Term Phase 4 Study

Parkinson's Disease | Parkinson Disease

Japan
Anand B. Karnad

Completed

Phase 0/1 Biomarker and Pharmacodynamic Study of Roflumilast in Patients With Advanced B-Cell Hematologic Malignancies (CTRC# 13-0013)

Advanced B-cell Lymphoid Malignancies

United States
University of Southern California
Aventis Pharmaceuticals

Completed

Estramustine, Docetaxel, and Carboplatin for Patients With Hormone Refractory Prostate Cancer Progressing After Mitoxantrone-Based Chemotherapy.

Prostate Adenocarcinoma

United States
AstraZeneca

Completed

A Chronic Obstructive Pulmonary Disease (COPD) Trial Investigating Roflumilast on Safety and Effectiveness in China, Hong Kong and Singapore: (ACROSS)

COPD

China, Hong Kong, Singapore
University Medical Centre Ljubljana

Completed

PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome

Obesity | PCOS

Slovenia
Tanta University

Completed

Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy

Diabetic Neuropathies | Type 2 Diabetes (Adult Onset)

Egypt
Children's Hospital Medical Center, Cincinnati
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge

Fragile X Syndrome

United States

Search clinical trials for: Roflumilast Placebo

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