Search clinical trials for: SAD, SHR-2004

Total 5071 results

Beijing Suncadia Pharmaceuticals Co., Ltd

Active, not recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single-dose Injection of SHR-2004 in Healthy Subjects

Prevention of Arterial and Venous Thrombosis

China
Inmagene LLC

Completed

Study to Evaluate IMG-004 in Healthy Participants

Healthy Participants

United States
JMackem Co., Ltd
Seoul National University Hospital

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects

Diabetic Neuropathies | Neuropathic Pain | Post Herpetic Neuralgia

Korea, Republic of
Hoffmann-La Roche

Completed

A Single Ascending And Multiple Ascending Dose Study of RO5271983 in Healthy Volunteers

Healthy Volunteer

New Zealand
Galapagos NV

Completed

A Study to Evaluate the Effects of a Single and Multiple Oral Doses of GLPG3121 in Adult, Healthy, Male Subjects

Healthy

Belgium
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
R&G Pharma Studies Co.,Ltd.

Completed

To Evaluate the Safety, Tolerability, and Pharmacokinetics Profile in Healthy Chinese Volunteers of TG-2349

Healthy Chinese Volunteers

China
ZYUS Life Sciences Inc.
Novotech (Australia) Pty Limited; ZYUS Life Sciences Australia Pty Ltd

Completed

Trichomylin® Safety, Tolerability & Pharmacokinetics in Healthy Adults and First in Human Osteoarthritis Pain Evaluation (HOPE)

Healthy | Osteoarthritis

Australia
Shanghai Jiatan Pharmatech Co., Ltd

Completed

Sudapyridine (WX-081) in Healthy Volunteers

Healthy

China
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of IBI356 in Healthy Participants and in Atopic Dermatitis Patients

Healthy Participants | Atopic Dermatitis Patients

China
EnnovaBio Australia Pharmaceuticals Pty Ltd

Not yet recruiting

A First-in-Human SAD/MAD Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ENC1018 in Healthy Adult Subjects

Healthy
Theravance Biopharma

Completed

SAD and MAD Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of TD-1473 in Healthy Subjects

Healthy

United States
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

Study on the Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-2004 Injection in Adult Patients With Atrial Fibrillation

Atrial Fibrillation
Pharmacobio

Recruiting

A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People

Alzheimer Disease

Korea, Republic of
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects (CHF6333 FIH)

Cystic Fibrosis | Non-Cystic Fibrosis Bronchiectasis

Belgium
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects

Healthy

Netherlands
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Atridia Pty Ltd.

Active, not recruiting

Phase I Study of SHR-2002 + SHR-1316 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

Australia
Syneos Health
SynerK Pharmatech (Suzhou) Limited

Recruiting

Dose Escalation of SNK-396 in Participants With Elevated Low-Density Lipoprotein Cholesterol

Elevated Low-Density Lipoprotein Cholesterol

Australia
Guangdong Hengrui Pharmaceutical Co., Ltd

Recruiting

A Phase I Study of SHR -2001 in Healthy Subjects

Healthy

China
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study of SHR-2005 Intravesical Instillation in the Treatment of High-risk Non-muscle Invasive Bladder Cancer (NMIBC)

High-risk Non-muscle Invasive Bladder Cancer

China
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Clarity Pharmaceuticals Ltd

Recruiting

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE) (SECuRE)

Prostatic Neoplasms, Castration-Resistant

United States
Aptabio Therapeutics, Inc.

Completed

Safety, Tolerability, PK and PD of SAD or MAD of APX-115 in Healthy Male Volunteers

Healthy | Safety

France
Ji Xing Pharmaceuticals Australia Pty Ltd
Novotech (Australia) Pty Limited

Recruiting

JX09 SAD/MAD in Healthy Participants

Resistant Hypertension

Australia
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 (CHF6001Ext)

Chronic Obstructive Pulmonary Disease

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
University Hospital Schleswig-Holstein

Completed

Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM)

Safety Issues | Pharmacokinetic

Germany
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Enrolling by invitation

A Trial of SHR-2002 Injection or Combined With Other Anti-cancer Medication in Advanced Malignant Tumors of Patients

Advanced Malignant Tumors

China
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
Clarity Pharmaceuticals Ltd

Recruiting

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy (CLARIFY)

Prostatic Neoplasms | Prostate Cancer

United States
Clarity Pharmaceuticals Ltd

Active, not recruiting

64Cu-SAR-BBN for Identification of Participants With Recurrence of Prostate Cancer (SABRE) (SABRE)

Biochemical Recurrence of Malignant Neoplasm of Prostate

United States
Johns Hopkins University
SARcode Bioscience

Terminated

SAR 1118 in Human Subjects Undergoing Pars Plana Vitrectomy

Pars Plana Vitrectomy | Diabetic Macular Edema (DME)

United States
Clarity Pharmaceuticals Ltd

Recruiting

64Cu-SAR-BBN and 67CU SAR-BBN for Identification and Treatment of Gastrin Releasing Peptide Receptor (GRPR)-Expressing Metastatic Castrate Resistant Prostate Cancer in Patients Who Are Ineligible for Therapy With 177Lu-PSMA-617 (COMBAT) (COMBAT)

Prostatic Neoplasms | Castration-Resistant

United States
Luke Nordquist, MD
Clarity Pharmaceuticals

Not yet recruiting

64Cu-SAR-bisPSMA Positron Emission Tomography of Patients With Known or Suspected Prostate Cancer

Prostate Cancer

United States
Clarity Pharmaceuticals Ltd

Completed

64Cu-SAR-bisPSMA for Identification of Participants With Recurrence of Prostate Cancer (COBRA) (COBRA)

Biochemical Recurrence of Malignant Neoplasm of Prostate

United States
Clarity Pharmaceuticals Ltd

Completed

Positron Emission Tomography (PET) Imaging of Participants With Confirmed Prostate Cancer Using 64Cu-SAR-bisPSMA (PROPELLER) (PROPELLER)

Prostatic Neoplasms

Australia
7 Hills Pharma, LLC
Frontage Clinical Services, Inc.

Completed

A Phase 1 SAD and MAD Study of the Safety, Tolerability and PK of 7HP349 in Normal Healthy Male Subjects

Solid Tumor

United States
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Salford
Northern Care Alliance NHS Foundation Trust

Completed

Assessing the Feasibility of Including Patients With Peripheral Artery Disease in to an Established Cardiac Rehabilitation Service.

Cardiovascular Diseases | Coronary Artery Disease | Peripheral Arterial Disease | Intermittent Claudication

United Kingdom
Soliton
Emergent Clinical Consulting, LLC

Completed

Proof of Concept (POC) Study of the Soliton's Acoustic Scar Reduction (ASR) Treatment for the Treatment of Keloid Scar (ASR)

Keloid Scar

United States
Istituto Clinico Humanitas

Recruiting

Epidemiologic, Clinical and Molecular Characteristics of Patients With Acute Respiratory Failure Affected by 2019-NCOV.

Covid19

Italy
Atridia Pty Ltd.

Completed

A Trial to Evaluate Safety and Tolerability of INCSHR01210 in Cancer Patients

Solid Tumors and Hematologic Malignancy

Australia
Janssen Scientific Affairs, LLC
HCA Research Institute, LLC

Recruiting

A Study to Assess the Engagement and Usefulness of Care4Today Digital Platform for Disease Management in Coronary Artery Disease (CAD) and/or Peripheral Artery Disease (PAD) Population (IPACE-CVD)

Coronary Artery Disease (CAD) | Peripheral Artery Disease (PAD)

United States
Kern Medical Center

Completed

Social Determinants of Health in Patients With Penetrating Trauma Injuries Before and During the COVID-19 Pandemic

COVID-19 | Social Determinants of Health | Penetrating Injury

United States
Sanjay Gandhi Postgraduate Institute of Medical...
Ram Manohar Lohia Institute of Medical Sciences, Lucknow

Terminated

Re-treatment of HCV Following DAA Failure

Chronic Hepatitis C

India
M.D. Anderson Cancer Center

Terminated

SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Vigonvita Life Sciences

Recruiting

Study of the Safety, Tolerability, Pharmacokinetics and Food Effects of VV119 Capsules in Chinese Healthy Volunteers

Schizophrenia

China
Medasense Biometrics Ltd

Terminated

Performance Assessment Of The PMD-200 In Subjects With Degenerative Lumbar Spine Disease Who Requires Surgical Procedure

Degenerative Diseases, Nervous System

Israel
Curacle Co., Ltd.
KCRN Research, LLC

Completed

First-In-Human Study of CU06-1004 Following Single and Multiple Ascending Doses in Healthy Volunteers

Diabetic Macular Edema

United States
Aura Biosciences

Terminated

Prospective Group-Matched Study With Belzupacap Sarotalocan (Bel-sar; AU-011) or Plaque Radiotherapy for Primary Indeterminate Lesions or Choroidal Melanoma (IL/ CM) (IL)

Choroidal Melanoma | Indeterminate Lesions

United States

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