Search clinical trials for: SC Methylnaltrexone

Total 573 results

Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP) (CHIP)

Adenomatous Polyposis Coli

Italy, United States, Belgium, Spain, Puerto Rico, Sweden, Israel, Czechia, Hong Kong, Hungary, Slovakia, South Africa, Ukraine, United Kingdom
Gruppo Oncologico Italiano di Ricerca Clinica
Mipharm SpA; Temas srl; Clirest s.r.l.; University Hospital of Parma: Department... and other collaborators

Unknown

Biomarker Study of Immune-mediated Mechanism of Action of Neoadjuvant Trastuzumab in HER2+ Breast Cancer Patients (IMMUN-HER)

Cancer, Breast

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Lymph Node Mapping in Finding Metastatic Disease in Patients With Sebaceous Gland Cancer of the Eyelid

Eyelid Sebaceous Gland Carcinoma

United States
NeuroDerm Ltd.

Completed

A Safety, Tolerability, and Plasma Concentration Study of Levodopa/Carbidopa Subcutaneous Solution (ND0612) in Parkinson's Disease (PD) Patients

Parkinson's Disease

Israel
National Cancer Institute (NCI)

Completed

Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers

Colorectal Neoplasm | Hereditary Nonpolyposis

United States
The Christie NHS Foundation Trust

Terminated

Effect of Pegvisomant on GH/IGF-I Relationship in GHD

Severe Adult Growth Hormone Deficiency

United Kingdom
Hoffmann-La Roche

Completed

A Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Participants With HER2-Positive Early Breast Cancer (FeDeriCa)

Early Breast Cancer

France, Spain, United States, Korea, Republic of, Canada, United Kingdom, Argentina, Belgium, Germany, Italy, Taiwan, Thailand, Japan, Brazil, Mexico, Czechia, Poland, Russian Federation, Ukraine
Steve N. Caritis, MD
AMAG Pharmaceuticals, Inc.

Terminated

17-OHPC in Pregnancy: IM vs SC Routes

Preterm Birth

United States
University of California, San Francisco

Completed

Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults (DBSVop)

Dystonia

United States
GlaxoSmithKline
Amgen

Completed

A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors

Fractures, Bone

Taiwan, Singapore, China
New York Medical College

Active, not recruiting

Mechanisms of Vasovagal Syncope

Postural Tachycardia Syndrome | Vasovagal Syncope

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

Familial Adenomatous Polyposis

United States
Northwestern University
Bristol-Myers Squibb; Lantheus Medical Imaging; CarThera

Recruiting

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma (SC9/ABX)

Glioblastoma | Glioblastoma Multiforme | Gliosarcoma | GBM | Recurrent Glioblastoma | Glioblastoma, IDH-wildtype

United States
Eli Lilly and Company

Terminated

A Study of LY2951742 in Participants With Mild to Moderate Osteoarthritis Knee Pain

Osteoarthritis, Knee

United States
National Cancer Institute (NCI)

Completed

Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps

Rectal Cancer | Colon Cancer

United States
National Cancer Institute (NCI)

Completed

Celecoxib in Treating Patients With Bladder Cancer

Recurrent Bladder Cancer

United States
Pfizer

Terminated

Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients

Familial Adenomatous Polyposis (FAP)

United States, Spain, Canada, Denmark
AstraZeneca

Completed

A Study to Examine the Effect of Pramlintide on Body Weight and Its Safety and Tolerability in Obese Subjects

Obesity

United States
Methodist Health System

Withdrawn

RELISTOR's Effects on Opioid-Induced Constipation

OIC

United States
Weill Medical College of Cornell University
Janssen Scientific Affairs, LLC

Recruiting

Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab

AL Amyloidosis | Amyloid | Refractory AL Amyloidosis

United States
Janssen Research & Development, LLC

Active, not recruiting

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer (PALOMA-3)

Advanced or Metastatic Non-small Cell Lung Cancer

Italy, United States, Germany, Japan, China, Korea, Republic of, Israel, Portugal, Taiwan, Thailand, Malaysia, United Kingdom, Australia, Turkey, Poland, Spain, Brazil, Canada, Argentina, France
Harpoon Therapeutics

Terminated

Study of HPN424 in Patients With Advanced Prostate Cancer

Advanced Prostate Cancer

United States, United Kingdom
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

Pregnancy Registry to Collect Long-Term Safety Data From Women Treated With HyQvia

Exposure During Pregnancy

Poland, Czechia, United States, Germany, Slovakia
Rajavithi Hospital
Ipsen; Chiang Mai University

Completed

Dysport® In Migraine Without Aura Prophylaxis : DIMWAP Study

Migraine Without Aura Prophylaxis

Thailand
University of British Columbia
Merck Frosst Canada Ltd.

Completed

Sitagliptin in the Elderly

Type 2 Diabetes

Canada
Case Comprehensive Cancer Center
National Cancer Institute (NCI); Mitaka USA, Inc.

Completed

Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients With Breast Cancer

Stage I Breast Cancer | Stage II Breast Cancer

United States
Eli Lilly and Company
Locemia Solutions ULC

Completed

Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia (AMG102)

Hypoglycemia

Canada
The University of Hong Kong
Hong Kong Council on Smoking and Health

Completed

Building Capacity and Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2016

Smoking Cessation

China
National Cancer Institute (NCI)

Completed

Celecoxib in Treating Postmenopausal Women Who Are Undergoing Surgery for Invasive Breast Cancer

Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer

United States
Assiut University

Completed

rTMS as a Treatment of Visceral Pain Secondary to Malignancy

Malignancy
MedSIR
Hoffmann-La Roche

Not yet recruiting

PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer (DEMETHER)

HER2-positive Breast Cancer
Janssen Research & Development, LLC

Active, not recruiting

Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Participants With Previously Untreated Multiple Myeloma

Multiple Myeloma

United States, France, United Kingdom, Belgium, Germany, Israel, Australia, Sweden, Canada, Netherlands, Austria, Ireland, Denmark
Beni-Suef University

Recruiting

Dydrogesterone, Cetrorelix Acetate and Triptorelin in Intra Cytoplasmic Sperm Injection Outcomes

IVF

Egypt
Dana-Farber Cancer Institute
Genentech, Inc.

Recruiting

ATEMPT 2.0: Adjuvant T-DM1 vs TH

Breast Cancer | HER2-positive Breast Cancer

United States
MedSIR
Hoffmann-La Roche

Active, not recruiting

Chemotherapy-Free pCR-Guided Strategy With Trastuzumab-pertuzumab and T-DM1 in HER2-positive Early Breast Cancer (PHERGAIN-2)

Early Breast Cancer

Spain, Italy, Germany, Bulgaria, Hungary
Clearside Biomedical, Inc.

Completed

Suprachoroidal Injection of CLS-TA Alone or With Aflibercept in Subjects With Diabetic Macular Edema (HULK)

Diabetic Macular Edema

United States
GlaxoSmithKline

Completed

Omalizumab to Mepolizumab Switch Study in Severe Eosinophilic Asthma Patients

Asthma

United States, Argentina, France, Germany, Spain, Canada, Sweden, Netherlands, Belgium
Jiangsu Simcere Pharmaceutical Co., Ltd.
Bristol-Myers Squibb

Unknown

A Phase 3 Study of Abatacept in Chinese Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate

Rheumatoid Arthritis (RA)

China
St Vincent's Hospital Melbourne
Merck Sharp & Dohme LLC

Unknown

A Pilot Study of Boceprevir for the Treatment of Genotype 6 HCV (HCV-6)

Chronic Hepatitis C

Australia
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype

Primary Ciliary Dyskinesia

United States
Seagen Inc.
Merck Sharp & Dohme LLC

Terminated

Safety Study of SEA-CD40 in Cancer Patients

Melanoma | Lymphoma | Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin | Carcinoma, Non-Small-Cell Lung | Carcinoma, Squamous Cell | Neoplasm Metastasis | Hodgkin Disease | Pancreatic Adenocarcinoma | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head... and other conditions

United States
Canadian Cancer Trials Group
AbbVie; Roche Pharma AG; Incyte Corporation

Recruiting

Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

Lymphoma, B-Cell

Canada
Emory University
National Cancer Institute (NCI); Genentech, Inc.

Completed

Secondary Primary Tumor Prevention With EGFR, OSI-774, and Cyclooxygenase-2

Head and Neck Cancer

United States
National Cancer Institute (NCI)

Completed

Celecoxib in Decreasing the Damaging Effects of Sunburn in Healthy Volunteers

No Evidence of Disease

United States
OHSU Knight Cancer Institute
Genentech, Inc.; Oregon Health and Science University; Servier Pharmaceuticals...

Recruiting

Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8

United States
Institut für Pharmakologie und Präventive Medizin
University of Erlangen-Nürnberg Medical School

Completed

Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes (ELMI)

Diabetes Mellitus Type 2

Germany
Tufts Medical Center

Terminated

Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids

Constipation

United States
Janssen Research & Development, LLC

Active, not recruiting

A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma

Multiple Myeloma

Australia, Poland, United Kingdom, United States, Belgium, Germany, Spain, Argentina, Portugal, Bulgaria, Romania, Serbia, Turkey, Ukraine, Japan, Greece, Korea, Republic of, Brazil, Russian Federation, Hungary, Czechia, Croatia, Ge... and more
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
National Cancer Institute (NCI)

Completed

Celecoxib in Preventing the Damaging Effects of Sunburn in Healthy Volunteers

No Evidence of Disease

United States

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