Search clinical trials for: SERPINA1 gene

Total 1175 results

Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Precision Medicine in the Prostate Cancer Care Pathway (PMPRC)

Prostate Cancer | Genetic Predisposition

United Kingdom
Biogen

Completed

A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111 (GEMINI)

Choroideremia

United States, Germany, France
Nanoscope Therapeutics Inc.

Enrolling by invitation

Non-interventional Long Term Follow-up Study of Participants Previously Enrolled in the STARLIGHT Study (SUSTAIN)

Stargardt Disease

United States
REGENXBIO Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)

Homozygous Familial Hypercholesterolemia (HoFH)

United States, Canada, Italy, Netherlands
Shenzhen Geno-Immune Medical Institute

Unknown

FANCA Gene Transfer for Fanconi Anemia Using a High-safety, High-efficiency, Self-inactivating Lentiviral Vector

Fanconi Anemia

China
Ege University

Completed

TGFB1 And LAMA1 Gene Polymorphisms in High Myopia

High Myopia | Gene Mutations
University of Alabama at Birmingham

Completed

Phase I Pilot Study of Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer

Cystic Fibrosis
Sohag University

Not yet recruiting

Gene Expression Of Suppressor Of Cytokines in In Cutaneous Warts

Warts
Aristotle University Of Thessaloniki

Not yet recruiting

Peri-implantitis and MMP-8

Peri-Implantitis
Lei Li

Recruiting

Genetic Mutation in Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Microsatellite Instability | PD-L1 | Nucleotide Variant | Copy Number Variation | Insertion-deletion Variation | Genomic Structural Variation | Total Mutation Burden | PD-1

China
Nanoscope Therapeutics Inc.

Enrolling by invitation

Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study (REMAIN)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies

United States, Puerto Rico
University of Oxford
University College, London; Moorfields Eye Hospital NHS Foundation Trust

Completed

REP1 Gene Replacement Therapy for Choroideremia (REGENERATE)

Choroideremia

United Kingdom
Uludag University

Unknown

PTEN-AKT-FOXO3 Gene Expression Relation With Low-ovarian Reserve in Endometriomas

Ovarian Reserve, Endometrioma, PTEN-AKT-FOXO3 Gene Expression

Turkey
Stanford University
University Medical Center Goettingen

Completed

Longitudinal Gene Expression Profiling in Adults After Traumatic Injury

Sepsis | Trauma | Infection

United States, Germany
Assiut University

Unknown

Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure

Heart Failure
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

S9431: Studying Genes and Immune Response in Tumor Samples From Patients With Locally Advanced or Metastatic Melanoma

Melanoma (Skin)
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Recurrent Malignant Gliomas

Brain and Central Nervous System Tumors

United States
Institute for Clinical and Experimental Medicine

Completed

Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors (MoliDon)

Kidney Transplantation | Acute Kidney Injury

Czechia
Asklepios Biopharmaceutical, Inc.

Recruiting

Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure (GenePHIT)

Congestive Heart Failure

United States
Invitae Corporation

Recruiting

Universal Germline Testing in the Community (UNITY)

Cancer | Solid Tumor | Solid Tumor, Adult

United States
Future University in Egypt

Completed

The Relationship of RAGE Gene Polymorphism With Type I Diabetes in Egyptian Patients

Type1diabetes

Egypt
Bin Li

Unknown

Efficacy Study of Gene Therapy for The Treatment of Acute LHON Onset Within Three Months (LHON)

Acute LHON | Onset Within Three Months | Onset Between 3 to 6 Months | Onset Between 6 to 12 Months | Onset Between 12 to 24 Months | Onset Between 24 to 60 Months | Onset Over 60 Months

China
Case Comprehensive Cancer Center

Withdrawn

Prevention of Recurrence and Metastasis in Genetically High-Risk Melanomas

Malignant Melanoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gene Expression in Samples From Patients With T-Cell Acute Lymphoblastic Leukemia

Lymphoma | Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Role of Biomarkers in Disease Progression in Samples From Patients With Acute Myeloid Leukemia

Leukemia
Systemix
National Cancer Institute (NCI)

Unknown

Gene Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma

Lymphoma

United States
Shanghai Chest Hospital

Recruiting

NGS-based Comprehensive Genomic ctDNA Panel in NSCLC With Immunotherapy

Lung Cancer

China
University of Basel
National Cancer Center, Korea; University Hospital, Geneva; Swiss National Science... and other collaborators

Recruiting

The DIALOGUE Study: Swiss-Korean Billateral Collaboration (DIALOGUE)

Breast Cancer | Ovarian Cancer | Hereditary Cancer

Switzerland
Medical College of Wisconsin

Recruiting

Genetic Variants and Susceptibility to Diseases of Prematurity in Very Low Birth-Weight Infants (CLD)

Chronic Lung Disease

United States
STZ eyetrial

Active, not recruiting

PDE6A Gene Therapy for Retinitis Pigmentosa (Pigment)

Retinitis Pigmentosa

Germany
New Approaches to Neuroblastoma Therapy Consortium
Children's Hospital Los Angeles; St. Baldrick's Foundation; The Evan Foundation; Rising Tide Foundation and other collaborators

Active, not recruiting

Neuroblastoma Precision Trial

Neuroblastoma

United States
Shanghai Chest Hospital

Unknown

NGS-based Large-panel in Targeted Drug Delivery and Immunotherapy of Lung Cancer

Lung Neoplasms

China
Targeted Genetics Corporation

Completed

Phase 1 Dose Escalation Study of Intra-Articular Administration of tgAAC94

Rheumatoid Arthritis

Canada, United States
Universidad Francisco de Vitoria
Sofía Laguarta Val; Alberto Melián Ortiz

Completed

Effectiveness of Muscular Work and Genetic Variants in Strength Gain of Ischiofemoral and Quadriceps

Genetics | Muscle Strength
Celgene

Recruiting

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

Neoplasms

United States, Belgium, Spain, Switzerland, Canada, France, Germany, Japan, Finland, United Kingdom, Austria, Italy, Netherlands, Norway, Sweden
Orchard Therapeutics
Ospedale San Raffaele

Active, not recruiting

Gene Therapy for Metachromatic Leukodystrophy (MLD)

Lysosomal Storage Disease | Metachromatic Leukodystrophy

Italy
Assistance Publique Hopitaux De Marseille

Unknown

BIOLOGICAL EXPLORATION OF THE VASCULAR FRACTION FROM THE ADIPOSE TISSUE OF PATIENTS WITH SCLERODERMIA (sclerabio)

Systemic Scleroderma

France
National Institute of Allergy and Infectious Diseases...

Completed

Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)

Severe Combined Immunodeficiency

United States
Jiayuan Sun

Completed

Mutation Detection of EBUS-TBNA Specimens Using NGS

Lung Cancer

China
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Completed

Using Gene Modified Neuroblastoma Cells for the Treatment of Relapsed/Refractory Neuroblastoma (CYCHE)

Neuroblastoma

United States
Targeted Genetics Corporation

Completed

Study of Intra-articular Delivery of tgAAC94 in Inflammatory Arthritis Subjects

Arthritis, Rheumatoid | Arthritis, Psoriatic | Ankylosing Spondylitis

United States
Nanoscope Therapeutics Inc.

Completed

Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE] (RESTORE)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies

United States, Puerto Rico
REGENXBIO Inc.

Active, not recruiting

A First-in-Human Study in Pediatric Patients With Ocular CLN2 Disease

Neuronal Ceroid Lipofuscinosis Type 2

United Kingdom
Helwan University

Completed

Role of NFKBIA and PTPN22 Genes Polymorphism in Acute Rejection Susceptibility After Living Donor Liver Transplantation in Egyptian Patients.

Liver Transplant Rejection

Egypt
AVROBIO

Terminated

A Long-Term Follow-up Study of Subjects With Gaucher Disease Who Previously Received AVR-RD-02

Type 1 Gaucher Disease

United States, Canada
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Non-small Cell Lung Cancer That Cannot Be Surgically Removed

Lung Cancer

United States
Atlas Biomed

Terminated

Study of the Genome, Gut Metagenome and Diet of Patients With Incident Parkinson's Disease

Parkinson Disease | Genetic Predisposition

Russian Federation
Atlas Biomed

Completed

Study of the Genome, Gut Metagenome and Lifestyle of Patients With Incident Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Genetic Predisposition | Metagenome

Russian Federation
Shire

Completed

Study of Velaglucerase Alfa Enzyme Replacement Therapy in Japanese Patients With Gaucher Disease

Gaucher Disease

Japan
Yiqi Du

Unknown

Study of Accurate Diagnosis and Treatment of Peutz-Jeghers Syndrome

Peutz-Jeghers Syndrome

China

Search clinical trials for: SERPINA1 gene

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