Search clinical trials for: SYN-010 42 mg

Total 1102 results

Bausch Health Americas, Inc.

Terminated

Study of Efficacy, Safety and Effect on Radiographic Progression of Brodalumab in Subjects With Psoriatic Arthritis (AMVISION-1)

Psoriatic Arthritis

United States, Italy, Spain, Hungary, Belgium, Mexico, Poland, Switzerland, United Kingdom, Russian Federation, Canada, Greece, France, Bulgaria, Slovakia, Estonia, Czech Republic
Janssen-Cilag International NV

Completed

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (ESCAPE-TRD)

Depressive Disorder, Major

Israel, Hungary, Korea, Republic of, Taiwan, Portugal, Turkey, Germany, Malaysia, Denmark, Bulgaria, Czechia, Belgium, Poland, Brazil, Netherlands, Argentina, Finland, Greece, South Africa, Austria, Kazakhstan, Norway, Sweden, United...
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
Eli Lilly and Company
CoLucid Pharmaceuticals

Completed

Three Doses of Lasmiditan (50 mg, 100 mg and 200 mg) Compared to Placebo in the Acute Treatment of Migraine (SPARTAN)

Migraine With or Without Aura

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic and Pharmacodynamic Study to Determine Blood Levels of JNJ-28431754 (Canagliflozin) in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Shanghai Henlius Biotech

Active, not recruiting

A Clinical Study to Compare the Efficacy, Safety and Immunogenicity of HLX04 and Bevacizumab Combined XELOX or mFOLFOX6 in the First-line Treatment of mCRC

Metastatic Colorectal Cancer (mCRC)

China
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Cardiac Safety of a Single Dose of AL-335 Administered on a Background of Simeprevir and Odalasvir and of Repeated Doses of Odalasvir Administered Alone in Healthy Participants

Healthy

United States
dr. P. Noordzij
Pharmacosmos A/S

Recruiting

Intravenous Iron to Treat Postoperative Anemia in Older Cardiac Surgery Patients (AGE-ANEMIA)

Iron Deficiency Anemia

Netherlands
Novo Nordisk A/S

Completed

A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease

Atherosclerotic Cardiovascular Disease

Germany, Poland, United States, Netherlands, Japan, Greece, Belgium
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Sumatriptan Succinate Tablets 100 mg to Imitrex® Tablets 100 mg

Healthy

United States
Janssen Research & Development, LLC

Completed

Study of Paliperidone Palmitate 3 Month and 1 Month Formulations for the Treatment of Patients With Schizophrenia

Schizophrenia

France, United States, China, Spain, Argentina, Mexico, Portugal, Bulgaria, Germany, Poland, Russian Federation, Ukraine, Japan, Greece, Taiwan, Korea, Republic of, Canada, Czech Republic, Brazil, Hungary, Austria, Sweden, Romania, Sl... and more
Mylan Pharmaceuticals Inc

Completed

Food Study of Sumatriptan Succinate Tablets 100 mg to Imitrex® Tablets 100 mg

Healthy

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

Locally Advanced Rectal Cancer

United States, Spain
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test Whether Four Capsules of 25 mg Nintedanib Are Taken up in the Body in the Same Way as One 100 mg Capsule

Healthy

Germany
Oregon Health and Science University

Completed

Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care

Substance Abuse, Intravenous | Hepatitis C | Substance Use Disorders

United States
Pfizer

Completed

Study to Evaluate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis (JADE Mono-1)

Dermatitis, Atopic

United States, Hungary, Canada, Germany, Australia, Czechia, Poland, United Kingdom
mariam hamouda

Completed

Effectiveness of Zinc Supplementation in Management of Patients With Symptomatic Benign Migratory Glossitis

Benign Migratory Glossitis

Egypt
Azienda Ospedaliera Universitaria Policlinico Paolo...

Completed

Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in G1b Treatment-Naïve, HCV-Infected Patients (EGG-18)

Chronic HCV Hepatitis

Italy
Taichung Veterans General Hospital
Merck Sharp & Dohme LLC

Terminated

Grazoprevir/Elbasvir for Genotype 1b Chronic Hepatitis C After Liver or Kidney Transplantation

Liver Transplant Infection | Kidney Transplant Infection | Chronic Hepatitis c

Taiwan
Jazz Pharmaceuticals
Evidilya S.r.l.

Not yet recruiting

Epidyolex® in Lennox Gastaut and Dravet Syndrome: an Observational Study in ITALY (EpiTALY)

Dravet Syndrome | Lennox Gastaut Syndrome

Italy
University of North Carolina, Chapel Hill
Allergan

Withdrawn

Effects of Eluxadoline (Viberzi®) 100 mg Twice Daily on Diarrhea-Associated Fecal Incontinence (ELXDFI)

Diarrhea | Fecal Incontinence | Urge Incontinence | Anal Incontinence | Accidental Bowel Leakage
University of Michigan

Terminated

OPTIMA-TBI Pilot Study (OPTIMA)

Mild Traumatic Brain Injury

United States
Janssen Research & Development, LLC
Merck Sharp & Dohme LLC

Completed

An Efficacy and Safety Study of Golimumab (CNTO 148) in Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative

United States, Canada, France, Poland, Ukraine, Germany, Israel, Bulgaria, India, Romania, Serbia, South Africa, Japan, Australia, Netherlands, Sweden, Belgium, New Zealand, Russian Federation, Czech Republic, Hungary, Austria, Denmark and more
Innovaderm Research Inc.

Not yet recruiting

Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy

Chronic Hand Eczema

Canada
Bausch Health Americas, Inc.

Terminated

P3 Study Brodalumab in Treatment of Moderate to Severe Plaque Psoriasis (AMAGINE-2)

Moderate to Severe Plaque Psoriasis

United States, Austria, France, Poland, Australia, Czechia, Canada, Hungary, Portugal, Spain, Netherlands
Takeda

Completed

Double-blind Comparative Study of SYR-472

Diabetes Mellitus

Japan
University of California, San Diego

Recruiting

Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 (PNLABXPART2)

Sepsis | Nephrolithiasis | Urinary Tract Infection (UTI)

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary

United States
Merck Sharp & Dohme LLC

Completed

Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
Janssen Research & Development, LLC

Completed

Study of Safety, Efficacy of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3007

Pain | Osteoarthritis

United States, Australia, Poland, Korea, Republic of, Canada, Germany, Hungary, Spain, Czechia, Sweden, United Kingdom
San Gerardo Hospital
IRCCS Policlinico S. Matteo; University of Milano Bicocca; Azienda L'ULSS 15... and other collaborators

Completed

Intraperitoneal Ropivacaine Nebulization for Pain Control After Laparoscopic Surgery

Laparoscopic Cholecystectomy

Italy
M.D. Anderson Cancer Center

Active, not recruiting

A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma

Recurrent Endometrial Carcinoma | Recurrent Endometrial Endometrioid Adenocarcinoma | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Refractory Endometrial Carcinoma | Refractory... and other conditions

United States
Bausch Health Americas, Inc.

Withdrawn

Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19

COVID19
Bausch Health Americas, Inc.

Completed

Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19

COVID19

Greece, Mexico
Yuhan Corporation

Completed

Food Effect on Pharmacokinetics of YH4808 in Healthy Male Subjects

Healthy

Korea, Republic of
New York State Psychiatric Institute
Clinilabs, Inc.

Recruiting

Clinical Trials of Multivalent Opioid Vaccine Components

Opioid-use Disorder

United States
Sandoz

Completed

Study to Test the Hypothesis of Non-inferior Efficacy and Safety of Ferrum Lek® (Iron (III) Hydroxide Polymaltosate), 100 mg Chewable Tablets (Lek d.d., Slovenia), as Compared With MALTOFER® (Vifor S.A., Switzerland), in Subjects With Mild and Moderate Iron Deficiency Anemia.

Mild and Moderate Iron-deficiency Anaemia

Russian Federation
University Medical Centre Ljubljana
University of Ljubljana School of Medicine, Slovenia

Completed

Duration of Doxycycline Treatment in EM Patients

Erythema Chronicum Migrans

Slovenia
Janssen Pharmaceutica N.V., Belgium

Completed

A Study of Guselkumab in Participants With Active Psoriatic Arthritis and an Inadequate Response to Anti-Tumor Necrosis Factor Alpha (Anti-TNF Alpha) Therapy (COSMOS)

Arthritis, Psoriatic

Belgium, France, Israel, Italy, Germany, Bulgaria, Spain, Poland, Russian Federation, United Kingdom, Ukraine, Hungary, Portugal, Greece
Midnight Pharma, LLC

Completed

Almorexant (ACT-078573) in Elderly Subjects With Chronic Primary Insomnia

Chronic Primary Insomnia

United States
University of Washington
National Center for Complementary and Integrative Health (NCCIH)

Withdrawn

Effects of Echinacea in Children

Upper Respiratory Infections
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Determine the Antiviral Activity of TMC310911 When Administered With Ritonavir in Treatment-Naive Human Immunodeficiency Virus - Type 1 (HIV-1) Infected Patients

Human Immunodeficiency Virus Type 1

Germany
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

Healthy Volunteers

United States
Instituto Nacional de Ciencias Medicas y Nutricion...
Gilead Sciences

Not yet recruiting

Elimination of Hepatitis C Virus Among Users of Substances (EHCUS)

Hepatitis C in Substance Users
Almirall, S.A.
Allergan

Completed

Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris

Acne Vulgaris

United States
GlaxoSmithKline

Completed

Study in Healthy Volunteers, to Evaluate the Safety, Efficacy and Dose Responses of SB-751689 (Ronacaleret)

Transplantation, Stem Cell

United States
University of Dundee

Completed

A Direct obserVed therApy vs fortNightly CollEction Study for HCV Treatment - ADVANCE HCV Study (ADVANCE)

Hepatitis C

United Kingdom
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study Comparing Sirukumab (CNTO 136) Monotherapy With Adalimumab (HUMIRA®) Monotherapy in the Treatment of Active Rheumatoid Arthritis (SIRROUND-H)

Arthritis, Rheumatoid

United States, Poland, Ukraine, Germany, Spain, Colombia, Mexico, Bulgaria, Romania, Serbia, South Africa, Chile, Russian Federation, Hungary, Lithuania, Moldova, Republic of
MedImmune LLC
MedImmune Ltd

Completed

A Study of Mavrilimumab in Subjects With Moderate-to-Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Bulgaria, Poland, Russian Federation, South Africa, Spain, Estonia, Hungary, Ukraine, Argentina, Chile, Germany, Serbia, Czech Republic, Colombia
Virginia Commonwealth University

Terminated

Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Pulmonary Hypertension

Pulmonary Hypertension

United States

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