Search clinical trials for: Saline Solution

Total 28915 results

Pneumagen Ltd.

Completed

Safety and Tolerability of Single and Multiple Doses of Neumifil

Viral Respiratory Tract Infection

United Kingdom
Pfizer

Completed

Clostridium Difficile Vaccine 2-Dose Versus 3-Dose Study

Clostridium Difficile Associated Disease

United States
Concert Pharmaceuticals
Cognitive Research Corporation

Completed

A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia

Schizophrenia

United States
Hoffmann-La Roche

Completed

A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases

Carcinoma, Hepatocellular | Liver Metastases | Biliary Tract Cancer | Secondary Liver Cancer

Korea, Republic of, Denmark, Spain, Taiwan, United States, Hong Kong
UCB Biopharma SRL

Completed

A Study to Test the Safety and Tolerability of UCB0107 in Study Participants With Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy

Belgium, Germany, Spain, United Kingdom
UCB Biopharma SRL

Completed

A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector for the Subcutaneous Self-injection of Bimekizumab Solution by Subjects With Active Psoriatic Arthritis

Psoriatic Arthritis

United States, Czechia, Germany, Hungary, Poland, Russian Federation
Genzyme, a Sanofi Company

Terminated

Study of Lademirsen (SAR339375) in Patients With Alport Syndrome (HERA)

Alport Syndrome

Australia, United States, China, France, Germany, Spain, United Kingdom
Radius Pharmaceuticals, Inc.

Terminated

A Study to Assess RAD011 (Cannabidiol Oral Solution) for the Treatment of Participants With Prader-Willi Syndrome (SCOUT-015)

Prader-Willi Syndrome

United States
Telavant, Inc.
Pfizer

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Intravenous and Multiple Subcutaneous and Intravenous Doses of PF-06480605 in Healthy Subjects.

Healthy

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Dupilumab-PEdiatric Skin Barrier Function and LIpidomics STudy in Patients With Atopic Dermatitis (PELISTAD)

Dermatitis Atopic

United States, United Kingdom
University of Alberta

Active, not recruiting

Normothermic Liver Preservation Trial

End Stage Liver Disease | Liver Diseases

Canada
Genzyme, a Sanofi Company

Completed

A Long-Term Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency

Sphingomyelin Lipidosis

United States, Belgium, Brazil, France, Germany, Italy, United Kingdom
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Characterization of Aerosol Generation and Transport in the Human Lung of Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Germany
Saol Therapeutics Inc

Active, not recruiting

Phase II Study to Assess Safety and Efficacy of SL-1002 for Osteoarthritic Knee Pain (COMPASS)

Osteoarthritis, Knee Pain

United States
Boehringer Ingelheim

Completed

Spesolimab (BI 655130) Single Dose in Generalized Pustular Psoriasis

Psoriasis

Taiwan, Malaysia, France, Japan, Korea, Republic of, Tunisia
Case Comprehensive Cancer Center

Withdrawn

Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma

Myeloma | Smoldering Myeloma | Monoclonal Gammopathy

United States
UCB Biopharma SRL

Completed

A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector for the Subcutaneous Self-injection of Bimekizumab Solution by Subjects With Moderate to Severe Chronic Plaque Psoriasis (PSO)

Moderate to Severe Chronic Plaque Psoriasis | Chronic Plaque Psoriasis

United States, Canada
Boehringer Ingelheim

Completed

A Trial in Healthy Chinese Volunteers to Test How Different Doses of BI 655130 Are Taken up in the Body

Healthy

China
Sanofi
Regeneron Pharmaceuticals

Completed

Single Dose Comparability Study of New and Current Dupilumab Drug Products Subcutaneously Administered in Healthy Adults

Healthy Volunteers

United States
Allergan

Completed

AGN-151586 Dose-Ranging Study for Treatment of Glabellar Lines

Glabellar Lines

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis (DIFFEREN-STAD)

Dermatitis Atopic

United States, Germany
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Dose Escalation Study of Oral VX-708 in Healthy Participants

Acute Pain

United Kingdom
AstraZeneca

Completed

Study to Assess the Safety, Tolerability, and Pharmacokinetics (Movement of Drugs Within the Body) of AZD2693 in Healthy Participants

Healthy Participants

Japan
Innovaderm Research Inc.
Ciusss de L'Est de l'Île de Montréal

Withdrawn

Effect of Bimekizumab in Patients With Psoriasis Vulgaris and Active Psoriatic Arthritis

Psoriasis Vulgaris | Active Psoriatic Arthritis
Australian and New Zealand Intensive Care Research...
Baxter Healthcare Corporation

Active, not recruiting

Intensive Nutrition in Critically Ill Adults (INTENT)

Critical Illness | Critically Ill

Australia, New Zealand
Novartis Pharmaceuticals

Completed

A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease

Dry Eye

United States
Fujita Health University
Elixirgen Therapeutics, Inc.

Completed

Safety and Immunogenicity of EXG-5003

COVID-19

Japan
Aptarion Biotech AG

Completed

Ascending Multiple Intravenous Doses of AON-D21 in Healthy Male Subjects.

Healthy

Germany
University Hospital, Ghent

Completed

Peritoneal Dialysis Versus Haemodialysis

Hemodialysis

Belgium
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Dose Escalation Study to Evaluate Safety and Pharmacokinetics (PK) of VX-840 in Healthy Participants

APOL1-mediated Kidney Disease

United States
MiWEndo Solutions S.L.
Hospital Clinic of Barcelona

Completed

Feasibility and Safety of MiWEndo-assisted Colonoscopy (MiWEndo1)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Adenocarcinoma | Colorectal Polyp | Colorectal Adenomatous Polyp

Spain
Janssen Research & Development, LLC

Completed

A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 4

Healthy

Belgium
University of Alabama at Birmingham
Alcon Research

Completed

Digital Device Users Who Are Treated With Systane Hydration PF

Dry Eye

United States
Taisho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of TS-142 in Healthy Adult Subjects.

Healthy Male Subjects

Japan
IGC Pharma LLC

Completed

Study of IGC-AD1 in Subjects With Dementia Due to Alzheimer's Disease

Dementia of Alzheimer Type

Puerto Rico
Connect Biopharma Australia Pty Ltd

Completed

Safety, Tolerability and Pharmacokinetics of CBP-174 in Healthy Adults

Healthy Adult Subjects

Australia
Sanofi
Regeneron Pharmaceuticals

Completed

Dupilumab Skin Barrier Function Study in Atopic Dermatitis (BALISTAD)

Atopic Dermatitis

United States, Canada
Boehringer Ingelheim

Completed

An Exploratory Maintenance Trial of BI 655064 in Patients With Lupus Nephritis

Lupus Nephritis

United Kingdom, Thailand, Germany, Japan, United States, Australia, Korea, Republic of, Hong Kong, Poland, Greece, Mexico, Czechia, Canada, Malaysia, Philippines, Portugal
University of Manchester
Royal College of Emergency Medicine

Completed

Qualitative Study of Long Term Cardiovascular Risk Prediction in the Emergency Department

Cardiovascular Diseases | Emergencies | Cardiovascular Risk Factor

United Kingdom
Annexon, Inc.

Active, not recruiting

A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy (ARCHER)

Geographic Atrophy

United States, Australia, New Zealand
Kyowa Kirin Pharmaceutical Development Ltd

Completed

Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH

X-linked Hypophosphatemia

United Kingdom, France, Ireland, Italy
Technoderma Medicines Inc.
Therapeutics, Inc.

Completed

A Phase 1 Study of TDM-105795 Topical Solution in Male Subjects With Androgenetic Alopecia (AGA) (AGA)

Alopecia, Androgenetic

United States
Sanofi

Completed

A Study on Safety and Tolerability of SAR425899 in Overweight to Obese Subjects and Type 2 Diabetes Mellitus Patients Not Requiring Anti-Diabetic Pharmacotherapy With an Optional 6-month Safety Extension Period

Type 2 Diabetes Mellitus

United States
Pinotbio, Inc.

Completed

Safety and Tolerability of NTX-101 in Korean Healthy Volunteers

Healthy Volunteers

Korea, Republic of
Sanko University
Kahramanmaras Sutcu Imam University

Completed

The Effects of Different Procedures on Pain Levels at Preterm and Term Infants in Neonatal Intensive Care Unit (PAIN)

Pain | Newborn | Preterm | Venipuncture | Term

Turkey
Sanofi
Regeneron Pharmaceuticals

Completed

Long-Term Safety Evaluation of Dupilumab in Patients With Asthma (LIBERTY ASTHMA TRAVERSE)

Asthma

Spain, Canada, Denmark, Belgium, Japan, Korea, Republic of, Mexico, United States, Israel, Brazil, Australia, France, Germany, United Kingdom, Argentina, Chile, Colombia, Hungary, Italy, Netherlands, Poland, Romania, Russian Federation and more
Locus Biosciences

Completed

Safety, Tolerability, and PK of LBP-EC01 in Patients With Lower Urinary Tract Colonization Caused by E. Coli

Urinary Tract Infections

United States
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

The Efficacy and Economics of Exercise Maintenance Post-Cardiac Rehabilitation (ECOPCR)

Coronary Artery Disease

Canada
Novartis Pharmaceuticals

Withdrawn

Assess Increased Mortality Risk With Each Year of Delayed Tobramycin Solution (TIS) Initiation, and Effect of TIS on Mortality Across Study Centers

Cystic Fibrosis
Mayo Clinic

Completed

A Pilot Study on the Use of Platelet Rich Plasma (PRP) for Facial and Hand Skin Rejuvenation (PRP)

Skin Aging of Face and Hands

United States

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