Search clinical trials for: Saxagliptin

Total 635 results

Michael A. Nauck

Completed

Feed-Back Suppression of Meal-Induced Glucagon-like Peptide 1 (GLP-1) Secretion

Type 2 Diabetes

Germany
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
Azienda Ospedaliero-Universitaria di Parma

Active, not recruiting

Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs (MIRACLE)

Newly Diagnosed Type 2 Diabetes

Italy
Ludwig-Maximilians - University of Munich

Completed

Sitagliptin Plus Granulocyte-colony Stimulating Factor in Acute Myocardial Infarction (SITAGRAMI)

Acute Myocardial Infarction

Germany
Merck Sharp & Dohme LLC

Completed

Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)

Type 2 Diabetes Mellitus
Chong Kun Dang Pharmaceutical

Completed

CKD-396 Drug-drug Interaction Study(A) (CKD-396 DDI(A) P1)

Diabetes Mellitus, Type II

Korea, Republic of
KineMed

Completed

The Effects of Co-admin of Colesevelam and Sitagliptin on Glucose Metabolism in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Vanderbilt University

Completed

Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome

Hypertension | Metabolic Syndrome

United States
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
Galenicum Health

Completed

Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.

Diabetes Mellitus, Type 2 | Bioequivalence

Mexico
Population Health Research Institute
Merck Sharp & Dohme LLC

Completed

Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)

Type 2 Diabetes Mellitus

Canada
Beni-Suef University
Minia University

Completed

Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Egypt
University of British Columbia
Merck Frosst Canada Ltd.

Completed

Sitagliptin in the Elderly

Type 2 Diabetes

Canada
Merck Sharp & Dohme LLC

Completed

Sitagliptin (MK-0431) vs. Placebo in Patients With Inadequate Glycemic Control on Metformin With Pioglitazone (MK-0431-128)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

A Study of MK0431 in Patients With Type 2 Diabetes (0431-010)

Diabetes Mellitus, Type II
Hvidovre University Hospital
University of Copenhagen

Completed

Degradation of the Anorexic Hormone Peptide YY

Healthy

Denmark
The Royal Bournemouth Hospital
Merck Sharp & Dohme LLC

Completed

How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin. (MSD-GLP1)

Type 2 Diabetes Mellitus

United Kingdom
Nagaoka Red Cross Hospital
Kurume University

Unknown

DPP-IV Inhibitors Underlying Mechanism of Cancer in Diabetic Patients

Type 2 Diabetes Mellitus

Japan
University of Dundee

Completed

DPP4inhibitors in Type 1 Diabetes

Type 1 Diabetes | Hypoglycaemia

United Kingdom
Medanta, The Medicity, India

Recruiting

Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver Transplantation (Dapa-LiT)

Diabetes Mellitus | Liver Transplant; Complications

India
GL Pharm Tech Corporation

Completed

Pharmacokinetic Characteristics of GLH1SM Extended Release Tablets in Healthy Volunteers(Fed)

Healthy

Korea, Republic of
University Hospital, Gentofte, Copenhagen

Completed

Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion (Px-Meal)

Diabetes After Total Pancreatectomy

Denmark
Merck Sharp & Dohme LLC

Completed

Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843)

Type 2 Diabetes Mellitus
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

The Role of P-glycoprotein in Sitagliptin Clinical Pharmacology

Healthy

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

Diabetes Mellitus, Type 2
University of Dundee

Completed

Study of Sulphonylurea Synergy With DPP4 Inhibitors (SSS)

Type 2 Diabetes

United Kingdom
Janssen Research & Development, LLC

Completed

An Efficacy Study of Canagliflozin or Sitagliptin to Determine Glucose Variability in Mexican Participants With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin (COMETA)

Diabetes Mellitus, Type 2

Mexico
First Affiliated Hospital Xi'an Jiaotong University

Unknown

Therapies on Newly Diagnosed Type 2 Diabetes Patients With High Glucose Toxicity Which Protect Islet β Cell (TOND)

Type 2 Diabetes Mellitus

China
Merck Sharp & Dohme LLC

Completed

MK0431/ONO-5435 Phase III Clinical Trial -Add-on to Voglibose Study for Patients With Type 2 Diabetes Mellitus (MK0431-104)

Diabetes Mellitus, Non-Insulin-Dependent
AstraZeneca
Eli Lilly and Company

Completed

A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)

Type 2 Diabetes Mellitus

United States, Mexico, India
Sanford Health
Juvenile Diabetes Research Foundation

Completed

Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes (REPAIR-T1D)

Type 1 Diabetes

United States
LG Life Sciences

Completed

Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study) (STABLE)

Type 2 Diabetes Mellitus

Korea, Republic of
National Institute of Diabetes and Digestive and...

Terminated

Novel Therapy to Preserve Beta Cell Function in New Onset Type 1 Diabetes

Autoimmune Diabetes | Diabetes Mellitus Type 1

United States
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Incretin-based Drugs and Pancreatic Cancer

Diabetes Mellitus, Type 2

Canada
University of Wisconsin, Madison
Heffter Research Institute; Etheridge Foundation

Recruiting

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

Opioid Use Disorder

United States
Movetis

Completed

Effect of Prucalopride in Patients With Severe Chronic Idiopathic Constipation

Chronic Constipation
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

PET and CT Scans to Evaluate Patients With Stage III or Stage IV Melanoma

Melanoma (Skin)

United States
Shanghai Jiao Tong University School of Medicine

Unknown

Metabolomic Variations in the Saxagliptin-Treated Type 2 Diabetes Mellitus Patients

Type 2 Diabetes

China
AstraZeneca

Completed

Description of Drug Utilization and Assessment of Impact of Saxagliptin on Health Status of Patients With Type 2 Diabetes in France (DIAPAZON)

Type 2 Diabetes Mellitus (T2D)
Duke University

Terminated

Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft Surgery (MAPSS)

Cardiovascular Disease | Type 2 Diabetes Mellitus

United States
Oslo University Hospital

Completed

Saxagliptin and Atherosclerosis (SAXATH)

Coronary Artery Disease | Diabetes Mellitus Type 2

Norway
AstraZeneca
Bristol-Myers Squibb

Completed

Evaluate Efficacy and Safety of Saxagliptin in Adult Patients With Type 2 Diabetes Inadequate Glycemic Control

Type 2 Diabetes

Korea, Republic of, Philippines, China, India
Peking University People's Hospital
Peking University First Hospital; Jiangsu Province Geriatric Institute

Recruiting

The Effect of Glimepiride Compared With Sitagliptin as an add-on Therapy to Metformin in Severe Insulin Deficiency Diabetes

Diabetes Mellitus, Type 2 | Severe Insulin Deficient Diabetes

China
Indiana University

Withdrawn

High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHD

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia, Adult | Bone Marrow Transplant Complications

United States
GL Pharm Tech Corporation

Completed

Pharmacokinetic Characteristics of GLH1SM Extended Release Tablets in Healthy Volunteers

Healthy

Korea, Republic of
Seoul National University Bundang Hospital

Completed

Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients

Type 2 Diabetes

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED)

Diabetes Mellitus, Non-Insulin-Dependent | Type 2 Diabetes Mellitus, Non Insulin Dependent
Foundation for the National Institutes of Health
Eli Lilly and Company; National Institute of Diabetes and Digestive and Kidney... and other collaborators

Unknown

Dynamic Responsiveness of Insulin Secretory Parameters To Sitagliptin and Glimeperide Administration in Type 2 DM

Type 2 Diabetes
Seoul National University Bundang Hospital

Completed

Sitagliptin Versus Insulin Dose Increase in Type 2 Diabetes on Insulin Treatment

Diabetes

Korea, Republic of

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