Search clinical trials for: Sedatives

Total 4242 results

Hoffmann-La Roche

Active, not recruiting

A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy (MAJESTY)

Primary Membranous Nephropathy

United States, China, Spain, Argentina, Brazil, France, Italy, Russian Federation, Israel, Poland, Turkey, Ukraine
Hoffmann-La Roche

Active, not recruiting

A Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis (REGENCY)

Lupus Nephritis

United States, Italy, Argentina, Germany, Colombia, South Africa, Poland, United Kingdom, Russian Federation, Brazil, France, Peru, Spain, Israel, Mexico
Cairo University

Completed

Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics

Anesthesia

Egypt
National Cancer Institute (NCI)

Completed

Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)

Urinary Bladder Neoplasms

United States
Tata Memorial Centre

Withdrawn

Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serum Biomarkers and on PBMCs in Breast Cancer Surgery

Female Breast Cancer

India
Ain Shams University

Completed

Lumbar Epidural Analgesia Versus Local Anesthesia With Dexmedetomidine Infusion in Endoscopic Lumbar Discectomy

Lumbar Disc Herniation

Egypt
Unity Health Toronto

Terminated

Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome (PHENOMANAL)

Alcohol Withdrawal | Alcohol Withdrawal Delirium | Alcohol Withdrawal Seizures

Canada
Global Alliance for TB Drug Development

Completed

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Pfizer

Completed

Sedation Of Adult Patients Undergoing Gastrointestinal Endoscopy: A Network Meta-analysis

Sedation | Gastrointestinal Endoscopy | Dexmedetomidine

Korea, Republic of
University of Sao Paulo General Hospital

Completed

Magnesium Sulfate Versus Dexmedetomidine on Anesthesia Awakening.

Cholecystectomy

Brazil
Tribhuvan University Teaching Hospital, Institute...

Completed

Comparison Of Dexmedetomidine And Dexamethasone As An Adjuvant To Bupivacaine In Brachial Plexus Block

Dexmedetomidine | Brachial Plexus Block | Dexamethasone | Bupivacaine

Nepal
Sanofi

Completed

A Drug to Drug Interaction Study of Sotagliflozin With Midazolam and Metoprolol

Type 2 Diabetes Mellitus

United States
Ain Shams University

Active, not recruiting

Dexmedetomidine Versus Magnesium Infusion in Reducing Agitations in Pediatric Patients Undergoing Adenotonsillectomy

Postoperative Agitations in Pediatric Patients

Egypt
King Khaled Eye Specialist Hospital

Completed

Late Onset Postoperative Nausea and Vomiting

Postoperative Nausea and Vomiting

Saudi Arabia
Ondokuz Mayıs University

Completed

Analgesia Management in Bariatric Surgery

Pain | Morbid Obesity | Bariatric Surgery Candidate | Postoperative

Turkey
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Next-Day Residual Effects of Gabapentin, Diphenhydramine and Triazolam on Simulated Driving Performance in Normal Volunteers

Healthy

United States
Beth Israel Deaconess Medical Center

Completed

The PATHFINDER Study: A Feasibility Trial (PATHFINDER)

Coronary Artery Disease | Delirium

United States
Lebanese American University

Completed

Opioid Free Anesthesia in Bariatric Surgery

Postoperative Pain | Bariatric Surgery Candidate | Postoperative Nausea and Vomiting | Opioid Use

Lebanon
Santa Barbara Cottage Hospital

Withdrawn

Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine (PKAT)

Alcohol Withdrawal Syndrome
Bayer

Completed

A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects Under Fed Conditions

Clinical Pharmacology

United States
Lehigh Valley Hospital

Completed

Treating Benign Paroxysmal Positional Vertigo (BPPV) in ED Patients

Benign Paroxysmal Positional Vertigo

United States
Montefiore Medical Center
M.D. Anderson Cancer Center; The University of Texas Health Science Center,...

Withdrawn

Preoxygenation With Optiflow™ in Morbidly Obese Patients is Superior to Face Mask

Obesity, Morbid
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Psoriasis

United States
Drexel University College of Medicine

Completed

Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions

Conscious Sedation Failure During Procedure

United States
Universidade Estadual Paulista Júlio de Mesquita...
University of Sao Paulo

Completed

Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics (ROCSEPSIS)

Sepsis | Systemic Inflammatory Response Syndrome | Septic Shock

Brazil
Charleston Laboratories, Inc

Completed

Phase III Study of the Safety and Efficacy of Cl-108 in the Treatment of Moderate to Severe Pain

Pain | Nausea | Vomiting

United States
Hopital Foch

Completed

Comparison of Different Propofol Formulations (Propofols)

General Anesthesia

France
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Randomized Trial of the Effectiveness of Topical "ABH Gel" vs. Placebo in Cancer Patients With Nausea

Nausea | Vomiting

United States
Chosun University Hospital

Completed

Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients (CSUHAPM)

Anesthesia | Elderly Patients | Emergence From Anesthesia | Effects of Dexmedetomidine | Recovery From Anesthesia

Korea, Republic of
AstraZeneca

Completed

AZD2066 Cocktail Study

Chronic Pain

United Kingdom
Pfizer

Completed

A Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Oral Doses Of PF-03716539 In Healthy Adult Subjects

Healthy Volunteers

Belgium
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Alcohol-Related Disorders | Alcohol Use | Alcohol Use Disorder (AUD)

United States
Jason Chui

Recruiting

Cerebral Flow-metabolism Coupling During Adult Surgery

Anesthesia

Canada
Aretaieion University Hospital

Recruiting

Opioid Sparing Anesthesia in Lumbar Spine Surgery

Pain, Postoperative | Analgesia | Pain, Acute | Ketamine | Dexmedetomidine | Pain, Chronic | Lidocaine | Analgesics | Lumbar Spine Surgery | Pain, Nociceptive

Greece
Minia University

Recruiting

Can Dexmedetomidine With Hyalase Augment Quality and Duration of Analgesia When Added to Lumbar Epidural Steroid in Failed Back Surgery. Randomized Double Blind Study

Pain, Neuropathic

Egypt
Mansoura University

Not yet recruiting

Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation

Patient With Nasolacrimal Duct Obstruction | External Dacryocystorhinostomy Operation

Egypt
Aretaieion University Hospital

Recruiting

Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine

Pain, Postoperative | Analgesia | Pain, Acute | Ketamine | Dexmedetomidine | Pain, Chronic | Pain, Neuropathic | Lidocaine | Central Nervous System Depressants | Analgesics | Pain, Nociceptive | Analgesics Non-narcotic

Greece
Mahidol University

Recruiting

Bilateral Superficial Cervical Plexus Block in Thyroid/Parathyroid Surgery

Hyperparathyroidism | Benign Tumor of Thyroid

Thailand
Helse Fonna

Recruiting

Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine. (VH)

Anesthesia, General | Anesthesia, Intravenous | Hemodynamic Instability

Norway
Hoffmann-La Roche

Completed

A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.

Acute Myeloid Leukemia

Australia, Italy, Canada, United Kingdom, United States, Denmark, Spain, Taiwan, Germany, France
Cairo University

Completed

Analgesic Efficacy of Sequential Rapid Versus Slow Intrathecal Injection Of Dexmedetomidine Followed by of Hyperbaric Bupivacaine in Inguinal Hernia Repair Surgery

Postoperative Pain

Egypt
Minia University

Completed

Ketamine Versus Dexmedetomidine in Supraclavicular Brachial Plexus Block

Supraclavicular Brachial Plexus Block

Egypt
Life Recovery Systems
Geisinger Clinic; Tulane University School of Medicine

Terminated

Helping Stroke Patients With ThermoSuit Cooling (SISCO)

Stroke | Brain Ischemia

United States
AstraZeneca

Completed

Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers

Healthy Volunteers

United States
Pardes Biosciences, Inc.

Completed

Study of PBI-0451 in Healthy Subjects.

Covid19

New Zealand
Washington University School of Medicine

Completed

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

Breast Cancer | Breast Cancer Female | Cancer of Breast

United States
Genprex, Inc.

Terminated

TUSC2-nanoparticles and Erlotinib in Stage IV Lung Cancer

Lung Cancer

United States
Al Mashfa Medical Center

Completed

Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy

Analgesia | Bariatric Surgery | Narcotics | Recovery Quality

Saudi Arabia
Chosun University Hospital

Completed

Effect of Dexmedetomidine After Thyroidectomy

Thyroid Tumor

Korea, Republic of
Menoufia University

Completed

Conscious Sedation for Epilepsy Surgery

Epilepsy

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