Search clinical trials for: Single ascending doses SUL-238

Total 599 results

Galapagos NV

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG3067 in Healthy Subjects.

Healthy

Belgium
National and Kapodistrian University of Athens

Unknown

Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture

Hip Fractures | Blood Loss, Surgical | Complication, Postoperative

Greece
GlaxoSmithKline

Completed

Primary Vaccination With Either Synflorix™ or Prevenar 13™ or Both Vaccines and Booster Vaccination With Synflorix™

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Mexico
Chr Hansen

Completed

Efficacy of a Probiotic Strain on Level of Markers of Inflammation in an Elderly Population

Inflammation

Ireland
Rockefeller University
University of Cologne

Completed

A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074

Healthy | HIV

Germany, United States
Abdul El-Rabbany

Recruiting

Antibiotics for Prevention of Infection Following Orthognathic Surgery

Orthognathic Surgical Site Infection

Canada
Contrad Swiss SA

Completed

Evaluation of the "ST500 SINGLE- DOSE GEL" in Patients With Symptomatic Long Head of the Biceps Tendon Injury

Long Head of Biceps Rupture

Italy
Nutrition Institute, Slovenia
MEDEDUS, Ljubljana, Slovenia; Vizera d.o.o.; Valens Int. d.o.o., Slovenija

Completed

Bioavailability Study of CoQ10 Formulations in Healthy Elderly Adults (CoQ10-01)

Bioavailability of Coenzyme Q10

Slovenia
Boehringer Ingelheim

Completed

Safety, Tolerance, and Pharmacokinetics of BILN 2061 ZW in Healthy Male Subjects, Combined With Preliminary Evaluation of Food Effect

Healthy
Juno Therapeutics, a Subsidiary of Celgene

Active, not recruiting

Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (TRANSCEND-NHL-001)

Follicular Lymphoma | Non-Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal B-cell Lymphoma | Mantle-cell Lymphoma

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Single and Multiple Dose Study to Explore the Safety and Pharmacokinetics of JNJ-39758979 In Healthy Male Volunteers of Either Caucasian or Japanese Descent

Healthy

United States
Meissa Vaccines, Inc.

Recruiting

Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults

Covid19

United States
Peking University Third Hospital

Completed

Comparison of Optical Quality With Different Placement of Refractive Multifocal Intraocular Lens

Cataract, Age-Related

China
Chong Kun Dang Pharmaceutical

Completed

Evaluation of the Safety and Tolerability of CKD-510 in Healthy Subjects

Healthy Volunteers

France
GlaxoSmithKline

Completed

To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944

Infections, Bacterial

United States
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease (BUSTON-01)

Dry Eye Disease
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease (BUSTON-02)

Dry Eye Disease
Virginia Commonwealth University
Gilead Sciences

Withdrawn

Rituximab, Idelalisib, and Venetoclax in Relapsed/Refractory CLL/SLL (RIVe-CLL/SLL)

Chronic Lymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | CLL | Refractory Small Lymphocytic Lymphoma | SLL | Relapsed CLL | Relapsed Chronic Lymphocytic Leukemia | Relapsed Small Lymphocytic Lymphoma
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Increasing Doses of BIBN 4096 BS in Healthy Male and Female Volunteers

Healthy
Human Genome Sciences Inc.
GlaxoSmithKline

Completed

Study of Belimumab Administered Subcutaneously to Healthy Subjects

Healthy

United States
Bayer

Completed

A Study to Learn How the Study Treatment BAY3283142 Taken as Single Dose by Mouth Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney Function of Similar Age, Gender, and Weight

Renal Impairment | Chronic Kidney Disease | Healthy Volunteers

Germany
Pfizer

Completed

A Study to Investigate the Effect of Tablet Formulation and Food on PF-07104091 in Healthy Participants

Healthy

United States
Daewoong Bio Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of rhEGF Eye Drops in Healthy Male Subjects

Dry Eye Syndromes

Korea, Republic of
Fundação de Medicina Tropical Dr. Heitor Vieira...

Completed

Efficacy and Safety of Pentamidine (7mg/kg) for Patients With Cutaneous Leishmaniasis Caused by L. Guyanensis

Cutaneous Leishmaniases
University of California, Los Angeles
Indivior Inc.

Unknown

Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals

Analgesic Response

United States
Acerus Pharmaceuticals Corporation

Completed

PK Study of Testosterone Nasal Gel (TBS-2) in Healthy Premenopausal Women

Female Sexual Dysfunction

United States
Washington University School of Medicine
Case Western Reserve University; University of Health and Allied Sciences

Completed

Safety and Efficacy of IDA for Onchocerciasis (DOLF IDA/Oncho)

Onchocerciasis

Ghana
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Non-fasting Conditions

Healthy

United States
Cloudbreak Therapeutics, LLC

Completed

Safety and Efficacy of CBT-001 Ophthalmic Solution in Patients With Pterygium (Pterygium)

Pterygium

United States
Boehringer Ingelheim

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of BIRT 2584 XX Administered as Multiple Doses and Safety and Pharmacokinetics of BIRT 2584 XX Administered With and Without Food as Single Dose to Healthy Male Volunteers

Healthy
Centre Francois Baclesse
Association de Neuro-Oncologues d'Expression Francaise

Active, not recruiting

Stereotactic Radiotherapy in Oligometastatic Brain Disease: a Randomised Phase III Study Comparing Hypofractionated Stereotactic Radiation Therapy (3*10 Gy) to the Historical Single-dose Radiosurgery (1*20 to 25 Gy) With Medico-economic Evaluation. (OligoBM-01)

Brain Metastasis | Oligoprogression

France
Contrad Swiss SA

Completed

Evaluation of the Effect of the "CR500 SINGLE-DOSE GEL" Medical Device in Patients With Knee Osteoarthritis (KOA)

Knee Osteoarthritis

Italy
Respivert Ltd

Completed

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Repeat Doses of RV1729 for 28 Days in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Indiana University
The National Center for Complementary and Integrative Health

Recruiting

Drug-gene-nutraceutical Interactions of Cannabidiol and Tacrolimus

Kidney Disease, Chronic | CBD | Transplant Complication

United States
Contrad Swiss SA

Completed

Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function

Knee Osteoarthritis | Knee Injuries | Pain, Acute | Knee Arthritis | Pain, Chronic | Knee Pain Swelling

Italy
MicuRx
Worldwide Clinical Trials

Completed

Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4

Safety
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Radboud University Medical Center

Completed

the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia (RISPENDO)

Autoimmune Diseases | Infection

Netherlands
The Cleveland Clinic

Completed

Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection

Overactive Bladder | Urge Incontinence | Urinary Incontinence, Urge | Overactive Bladder Syndrome

United States
Takeda

Withdrawn

A Safety and Efficacy Study of Ramelteon Tablets for Sublingual Administration (TAK-375SL) in the Maintenance Treatment of Bipolar 1 Disorder

Bipolar Disorder
Uniformed Services University of the Health Sciences
Naval Medical Research Center; Navy Bureau of Medicine and Surgery; Ministry... and other collaborators

Terminated

Trial Evaluating Ambulatory Treatment of Travelers' Diarrhea (TrEAT TD)

Acute Watery Diarrhea | Dysentery/Febrile Diarrhea

Afghanistan, Djibouti, Honduras, Kenya, Thailand
Laboratorios Silanes S.A. de C.V.

Completed

Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers (NTC00940472)

Healthy

Spain
Medicines for Malaria Venture
University of Cape Town

Terminated

Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers

Malaria

South Africa
Agios Pharmaceuticals, Inc.

Completed

A Phase I Study of AG-348 in Healthy Volunteers (AG-348 SAD)

Healthy Volunteer

United States
GlaxoSmithKline

Completed

To Investigate Effects GSK561679 on Part of the Body's System That Controls the Balance of Many of the Hormones.

Depressive Disorder and Anxiety Disorders

United Kingdom
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions

Healthy

United States
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Massachusetts General Hospital; Stanford University

Completed

Randomized Study Comparing Local Tumor Control After Post-Operative Single-Fraction or Hypofractionated Stereotactic Radiosurgery in the Treatment of Spinal Metastases

Spinal Metastases

United States
Prana Biotechnology Limited

Completed

Absorption, Metabolism and Excretion Study of [14C]PBT2 and Absolute Bioavailability of PBT2

Healthy Volunteers

United Kingdom
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of KUC 7483 CL Tablets in Healthy Male Volunteers

Healthy

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