Search clinical trials for: Sitagliptin placebo

Total 54359 results

Merck Sharp & Dohme LLC

Completed

A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253)

Type 2 Diabetes Mellitus
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Effect of DPP4 Inhibition on Growth Hormone Secretion

Obesity

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes

Diabetes Mellitus, Type II | Diabetes Mellitus, Non Insulin Dependent

United States, Poland, Bulgaria, India, Malaysia, Romania, Canada, Russian Federation, Argentina, Puerto Rico, Czech Republic, United Kingdom, Mexico
Janssen Research & Development, LLC

Completed

The CANTATA-MP Trial (CANagliflozin Treatment and Trial Analysis - Metformin and Pioglitazone)

Diabetes Mellitus, Type 2

United States, Germany, Spain, Mexico, India, Canada, Greece, Thailand, United Kingdom, Finland, France
Emory University

Terminated

Prevention of Cystic Fibrosis Diabetes (Prevent)

Cystic Fibrosis | Prediabetes

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Study To Evaluate Methods To Evaluate Back Pain

Pain

United States
Kanazawa University

Unknown

Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver Diseases

Type 2 Diabetes Mellitus | Chronic Liver Disease

Japan
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Inflammatory Bowel Disease (CONNECT-IBD)

Inflammatory Bowel Diseases | Crohn's Disease | Ulcerative Colitis

France, Spain, United Kingdom, Czechia, Italy, Belgium, Germany, Netherlands, Greece, Finland, Hungary, Portugal, Slovakia
Hoffmann-La Roche

Completed

A Study in Participants With Asthma Initiating Treatment With Omalizumab (Xolair)

Asthma

United States
Ankara Education and Research Hospital

Unknown

The Role of Glutamine for Preventing Oxaliplatin-Induced Peripheral Neuropathy (GELUPO)

Peripheral Neuropathy

Turkey
University Hospital, Gentofte, Copenhagen
Eli Lilly and Company

Completed

The Role of Glucagon in the Effects of Dipeptidyl Peptidase-4 Inhibitors and Sodium-glucose Co-transporter-2 Inhibitors

Type 2 Diabetes

Denmark
Prof. Dr. Thomas Forst

Completed

Saxagliptin in Combination With Dapagliflozin - Effects on Islet Cell Function

Type2 Diabetes Mellitus

Germany
Boehringer Ingelheim
Eli Lilly and Company

Completed

Linagliptin and Metformin Versus Linagliptin in Newly Diagnosed, Untreated Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Canada, India, Israel, Malaysia, Mexico, Philippines, Puerto Rico, Russian Federation, Sri Lanka, Thailand, Ukraine
AstraZeneca

Completed

A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 Diabetes

Type 2 Diabetes Mellitus | Inadequate Glycaemic Control

United States, Canada, Czechia, Germany, Russian Federation, Mexico
AstraZeneca

Completed

Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg

Type 2 Diabetes

United States, Argentina, Mexico, Israel
Brigham and Women's Hospital

Completed

Replication of the TECOS Diabetes Trial in Healthcare Claims

Diabetes

United States
National Institute of Diabetes and Digestive and...

Completed

Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

Diabetes Mellitus Type 2 | Diabetes Mellitus Type 1

United States
Novo Nordisk A/S

Completed

A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Daily in Japanese Subjects With Type 2 Diabetes (SUSTAIN™)

Diabetes Mellitus, Type 2 | Diabetes

Japan
University Hospital, Basel, Switzerland

Completed

Effects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 Diabetes (EXTYPE-1)

Diabetes Mellitus Type 1

Switzerland
Nemours Children's Clinic

Completed

Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis

Cystic Fibrosis

United States
Handok Inc.

Unknown

Exploratory Study to Compare the Effects of Tenelia® or Januvia® on Glucose Variability in add-on to Metformin (CGMS Study)

Type 2 Diabetes Mellitus

Korea, Republic of
Stanford University
Merck Sharp & Dohme LLC

Completed

Study of the Effect of Sitagliptin on Glucose (Sugar) Metabolism in Patients With Heart Failure (S-001)

Heart Failure, Congestive

United States
Boehringer Ingelheim
Eli Lilly and Company

Completed

30 Week Parallel Group Comparison Study of Linagliptin + Pioglitazone (5+15, 5+30 and 5+45 mg) qd Versus Respective Monotherapies, Followed by a Comparison of 5mg+30mg and 5mg+45mg Versus Respective Monotherapies in Type 2 Diabetes for up to 54 Weeks

Diabetes Mellitus, Type 2

United States, Estonia, Germany, Latvia, Spain, United Kingdom
Boehringer Ingelheim
Eli Lilly and Company

Completed

Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Japanese Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Japan
Merck Sharp & Dohme LLC

Terminated

The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118)

Diabetes Mellitus Non-insulin-dependent
Novo Nordisk A/S

Completed

The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With Insulin (BEGIN™)

Diabetes Mellitus, Type 2 | Diabetes

United States, India, Argentina, Turkey, Canada, South Africa, Mexico
University of Zurich
European Foundation for the Study of Diabetes

Completed

Role of Interleukin-6 in Exercise (Exil-6)

Obesity | Diabetes Mellitus, Type 2

Switzerland
Dong-A ST Co., Ltd.

Completed

Efficacy and Safety of Evogliptin add-on to Metformin in Patients With type2 Diabetes

Type 2 Diabetes Mellitus

Korea, Republic of
Indiana University School of Medicine

Completed

Sitagliptin Umbilical Cord Blood Transplant Study

Lymphoma, Non-Hodgkin | Leukemia, Myeloid, Acute | Acute Lymphoblastic Leukemia | Myelodysplasia | Leukemia, Myelogenous, Chronic

United States
The Catholic University of Korea
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics Study of Dipeptidyl Peptidase 4 Inhibitor to Control Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

A Post Marketing Safety Study of Sitagliptin (JANUVIA®) (MK-0431-234)

Diabetes Mellitus, Type 2
Charles Drew University of Medicine and Science
National Center for Research Resources (NCRR)

Completed

Sitagliptin in Combination With Metformin and Sulfonylurea

Type 2 Diabetes Mellitus

United States
Eli Lilly and Company

Completed

A Study of LY2189265 and Sitagliptin in Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
Novartis

Completed

Glycemic Holter Study (Continuous Glucose Monitoring) - (OPTIMA)

Type 2 Diabetes Mellitus

France
Boehringer Ingelheim

Completed

Relative Bioavailability of Two Fixed Dose Combination Tablets of Linagliptin/Pioglitazone Compared With Single Linagliptin and Pioglitazone Tablets Administered Together to Healthy Male and Female Subjects

Healthy
GRADE Study Group
Bristol-Myers Squibb; National Institute of Diabetes and Digestive and Kidney... and other collaborators

Completed

A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes (GRADE)

Type 2 Diabetes | Comparative Effectiveness of Glycemia-lowering Medications

United States
Albert Einstein College of Medicine
Medtronic

Completed

Randomized Trial Comparing Sitagliptin to Placebo in Closed Loop

Diabetes Mellitus, Type 1

United States
Beni-Suef University

Not yet recruiting

Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients

Polycystic Ovary Syndrome

Egypt
Chipscreen Biosciences, Ltd.

Completed

Study of Chiglitazar Compare With Sitagliptin in Type 2 Diabetes Patients (CMAS)

Type 2 Diabetes

China
Merck Sharp & Dohme LLC

Completed

Efficacy of Sitagliptin and Glibenclamide on the Glucose Variability in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431-355)

Type 2 Diabetes Mellitus
University of Missouri-Columbia

Withdrawn

Effects of DPP-4 Inhibition on Calcium and Bone Metabolism in Type 2 Diabetes Mellitus

Type 2 Diabetes

United States
Merck Sharp & Dohme LLC

Completed

An Open-Label, Single- & Multiple-Dose Study to Investigate the Pharmacokinetics of Sitagliptin 100 mg in Healthy Chinese Adult Subjects (0431-108)(COMPLETED)

Diabetes Mellitus Non-insulin-dependent
Sung-Chen Liu
Mackay Memorial Hospital

Completed

Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea (JAS)

Type 2 Diabetes

Taiwan
Assaf-Harofeh Medical Center

Unknown

The Effect of Sitagliptin on Hypertension, Arterial Stiffness, Oxidative Stress and Inflammation

Diabetes Mellitus | Arterial Stiffness

Israel
AstraZeneca

Completed

A Study to Evaluate the Effect of Dapagliflozin With and Without Saxagliptin on Albuminuria, and to Investigate the Effect of Dapagliflozin and Saxagliptin on HbA1c in Patients With Type 2 Diabetes and CKD

Type 2 Diabetes Mellitus, CKD and Albuminuria

United States, Spain, Canada, Korea, Republic of, Mexico, Japan, Taiwan, Australia, South Africa
Novo Nordisk A/S

Completed

Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus. (PIONEER 7)

Diabetes Mellitus, Type 2 | Diabetes

United States, Austria, Belgium, Norway, Turkey, Switzerland, Argentina, Korea, Republic of, Brazil, Egypt
National University of Malaysia

Completed

Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus (GLP-1)

Type 2 Diabetes Mellitus | PreDiabetes

Malaysia
Sherif S. Farag

Completed

Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Graft vs Host Disease

United States
Novartis

Completed

Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency (28-week Extension Study)

Diabetes Mellitus, Type 2 | Renal Insufficiency

United States

3

Subscribe