Search clinical trials for: Sofosbuvir-Velpatasvir Drug Combination

Total 4883 results

ANRS, Emerging Infectious Diseases

Completed

Feasibility, Tolerance and Efficacy of Interferon-free, Antiviral Treatment With Sofosbuvir + Ribavirin for the Treatment of Genotype 2 and Sofosbuvir/Ledipasvir for the Treatment of Genotype 1 and 4 Hepatitis C Virus-infected Patients in West and Central Africa (TAC)

HIV Infection | Hepatitis C

Cameroon, Côte D'Ivoire, Senegal
Gilead Sciences

Completed

Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-Dose Combination ± Ribavirin in Cirrhotic Subjects With Chronic Genotype 1 HCV Infection

HCV Infection

France
Gilead Sciences

Completed

Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir (SOF/VEL) Fixed-Dose Combination (FDC) and Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX ) FDC for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) Infection

Hepatitis C Virus Infection

Korea, Republic of
Mitsubishi Tanabe Pharma Corporation
Toray Industries, Inc

Completed

Efficacy and Safety of MP-424, Interferon Beta (IFN Beta), and Ribavirin(RBV) in Treatment-Naïve or Having Received Interferon Based Therapy With Chronic Hepatitis C (CHC)

Chronic Hepatitis C(CHC)

Japan
Genuine Research Center, Egypt
MinaPharm Pharmaceuticals

Completed

A Study of Sofosbuvir and Ledipasvir From Soviredia 90/400 mg Tablets (Minapharm, Egypt) Versus Harvoni 90/400 mg Tablets (Gilead Sciences, USA)

Healthy

Egypt
Genuine Research Center, Egypt
Magic Pharma, Egypt

Completed

A Study of Sofosbuvir and Ledipasvir From Magicbuvir Plus 90/400 mg Tablets (Magic Pharma, Egypt) Versus Harvoni 90/400 mg Tablets (Gilead Sciences, USA)

Healthy

Egypt
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination +/- Ribavirin in Adolescents and Children With Chronic HCV-Infection

Hepatitis C Virus Infection

United States, New Zealand, Australia, United Kingdom
Saint Michael's Medical Center

Completed

Sofosbuvir, Ribavirin, for the Treatment of Chronic Hepatitis C Virus Genotype 1 in HIV-Coinfected Patients Receiving Fixed Dose Co-formulation Emtricitabine/ Tenofovir/Cobicistat/Elvitegravir: A Pilot Study

HIV Infection | Hepatitis C Infection

United States
Gilead Sciences

Completed

Safety and Efficacy of LDV/SOF Fixed-Dose Combination (FDC) ± Ribavirin in HCV Genotype 1 Subjects

Chronic Hepatitis C Virus

United States
Ain Shams University

Recruiting

Clinical Pharmacokinetics of Daclatasvir/Sofosbuvir in Adolescents With Hepatitis C Virus

Chronic HCV Infection

Egypt
Institute of Liver and Biliary Sciences, India

Terminated

To Evaluate the Safety and Efficacy of Sofosbuvir and Ribavirin in Patients With HCV (Genotype 3) Related Decompensated Cirrhosis

HCV Related Cirrhosis

India
Gilead Sciences

Completed

Efficacy, Safety, and Tolerability of Ledipasvir/Sofosbuvir (LDV/SOF) Treatment for HIV/HCV Co-infected Participants Who Switch to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) or Emtricitabine/Rilpivirine/Tenofovir Alafenamide (F/R/TAF) Prior to LDV/SOF HCV Treatment (Co-STARs)

HIV-1 Infection | HCV Infection

United States, Puerto Rico
Tanta University

Unknown

Sofosbuvir in Treatment of COVID 19

COVID

Egypt
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Grazoprevir (MK-5172), Elbasvir (MK-8742), and Sofosbuvir for Chronic Infection With Hepatitis C Virus Genotypes 1 and 3 (MK-5172-074)

Hepatitis C
Stanford University
Gilead Sciences

Completed

Comparative Efficacy of Fixed-dose Combination Sofosbuvir + Ledipasvir, 8 vs. 12 Weeks in Chronic Hepatitis C Genotype 6

PT-NANBH

United States
Ottawa Hospital Research Institute
Gilead Sciences; CIHR Canadian HIV Trials Network

Completed

HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection (CTN289)

Hepatitis C, Chronic | Human Immunodeficiency Virus

Canada
Iran Hepatitis Network
Baqiyatallah Research Center for Gastroenterology and Liver Diseases

Unknown

Treatment of Hepatitis C Virus Infection With Generic Sofosbuvir/Ledipasvir in Iranian Patients (HepCC-2)

Hepatitis C
ANRS, Emerging Infectious Diseases

Recruiting

Study of DAA Treatment for Children and Adolescents With Active HCV Infection in Cambodia (HEPEDIAC)

HCV Infection

Cambodia
Assiut University

Recruiting

Levels of Interleukin-6 andTransforming Growth Factor Beta in HCV Patients Sera

Hepatitis C, Chronic

Egypt
Ascletis Pharmaceuticals Co., Ltd.

Completed

A Study of the Relative Bioavailability of ASC18 Tablets vs Reference Tablets in Healthy Volunteers

Healthy

China
Sunshine Lake Pharma Co., Ltd.

Completed

The Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC110114 Tablets in HCV-infected Subjects (HEC110114)

Chronic Hepatitis C

China
MassBiologics

Terminated

Open Label Study of the Efficacy and Safety of MBL-HCV1 in Combination With Oral Direct-Acting Antivirals in Patients Undergoing Liver Transplantation for Hepatitis C (MBL-HCV1)

Hepatitis C Infection

United States
Drugs for Neglected Diseases
Ministry of Health, Malaysia; Ministry of Health, Thailand; National Science...

Active, not recruiting

Strategic Transformation of the Market of HCV Treatments (STORM-C-1)

Hepatitis C

Malaysia, Thailand
Assiut University

Unknown

Assessment Effects After Direct Acting Antiviral in Chronic Hepatitis c Virus Patients

Chronic Hepatitis c

Egypt
University of Florida
Vertex Pharmaceuticals Incorporated

Completed

Open-Label Safety Study of Telaprevir and Sofosbuvir in Chronic Hepatitis C Genotype 1 (STEADFAST)

Hepatitis C, Chronic

United States
Tanta University

Completed

Safety and Efficacy of Sofosbuvir-Based Regimens in the Treatment of Egyptian Patients With Hepatitis C Infection

Hepatitis C

Egypt
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Treatment-Experienced Subjects With Genotype 1 HCV Infection (ION-2)

Chronic Hepatitis C Virus

United States
Alexandria University

Completed

Evaluation of Sofosbuvir and Daclatasvir Combo in COIVD-19 Patients in Egypt

Covid19

Egypt
Sherief Abd-Elsalam

Recruiting

Effect of Sofosbuvir-daclatasuvir on Angiogenesis

HCV Coinfection

Egypt
MTI University

Unknown

The Renal Safety in Patients With Chronic HCV Undergoing Sofosbuvir Containing Antiviral Therapy

Egyptian Patients, HCV Treatment, Kidney Function

Egypt
Tehran University of Medical Sciences

Completed

Sofosbuvir and Daclatasvir in Treating Hepatitis C, A Study on 1000 Patients (SD1000)

Hepatitis C

Iran, Islamic Republic of
Myanmar Oxford Clinical Research Unit
Medical Action Myanmar; Myanmar Liver Foundation

Withdrawn

Hepatitis C Treatment Study in Myanmar

Hepatitis C

Myanmar
Humanity and Health Research Centre
Beijing 302 Hospital; Nanfang Hospital of Southern Medical University

Completed

DAAs Treatment for Chronic HCV/HBV Co-infection Patients(DASCO) (DASCO)

Chronic Hepatitis C Infection | Hepatitis B Reactivation | HBV Coinfection

China
Ain Shams University

Unknown

Metabolic Changes in Chronic HCV Patients Receiving DAAS (HCV DAAS)

Chronic Hepatitis C

Egypt
Egyptian Liver Hospital
Wadi El Nil Hospital

Completed

A Study to Evaluate the Safety and Efficacy of the Combined Single Dose of Dactavira Plus Or Dactavira in Egyptian Adults With Chronic Genotype 4 HCV Infection

Hepatitis C

Egypt
ANRS, Emerging Infectious Diseases

Completed

DRug Use & Infections in ViEtnam - Hepatitis C (DRIVE-C) (DRIVE-C)

Hepatitis C | Viral Hepatitis C | Drug Use

Vietnam
Sherief Abd-Elsalam
Benha University

Unknown

Effect of Direct-acting Antiviral Drugs on Erectile Function

Hepatitis C

Egypt
Sunshine Lake Pharma Co., Ltd.

Completed

Phase 3 Study of Yimitasvir Phosphate Capsules

Chronic HCV Infection

China
Ain Shams University

Completed

Sofosbuvir and Simeprevir Versus Sofosbuvir and Ribavirin in Treatment of HCV

HCV
Assiut University

Not yet recruiting

the Pulmonary Safety of Antihepatitis C Treatment

Hepatitis C
Muhammad Radzi Abu Hassan

Recruiting

8- Versus 12-week of Sofosbuvir-ravidasvir Treatment of Chronic Hepatitis C

Hepatitis C

Malaysia
Mohamed Saad

Unknown

Role OF OCT-A TO Detect Possible Retinal Vascular Complications of Sofosbuvir in Patients With Hepatitis C

HCV Infection

Egypt
Sunshine Lake Pharma Co., Ltd.

Completed

Phase 2 Study of Yimitasvir Phosphate Capsules

Chronic HCV Infection

China
Right to Care
Boston University; University of California, Los Angeles; Alliance for Public... and other collaborators

Completed

Simplified Antiviral Treatment Strategy for Hepatitis C in Ukraine

Hepatitis C Virus

Ukraine
University of Texas Southwestern Medical Center
Memorial Sloan Kettering Cancer Center; Weill Medical College of Cornell University

Terminated

Oral Hepatitis C Treatment for Indolent Lymphoma (OPTImaL) Study (Optimal)

Liver Disease

United States
Egyptian Liver Hospital

Unknown

Safety & Efficacy of Sofosbuvir 400mg/Ledipasvir 90mg in the Treatment of Chronic Hepatitis C Adolescents

Hepatitis C Virus Infection, Response to Therapy of

Egypt
Federal University of São Paulo

Completed

Randomized Clinical Trial of Sofosbuvir in Combination With Daclatasvir or Simeprevir for 12 Weeks in Non-cirrhotic Subjects Infected With Chronic Hepatitis C Virus Genotype 1 (TNT)

Hepatitis C, Chronic

Brazil
ANRS, Emerging Infectious Diseases

Completed

Study to Assess Efficacy and Safety of Grazoprevir/Elbasvir Associated With Sofosbuvir and Ribavirin in HCV Genotype 1 or 4-infected Patients Who Failed Direct Acting Antivirals (DAA) Bitherapy With Sofosbuvir

Hepatitis C
Tehran University of Medical Sciences
Shiraz University of Medical Sciences; Ahvaz Jundishapur University of Medical... and other collaborators

Completed

Treating Hepatitis C in CRF Using Sofosbuvir and Daclatasvir (SD-CRF)

Hepatitis C, Chronic | Chronic Renal Failure

Iran, Islamic Republic of
University of Witwatersrand, South Africa

Completed

COVID-19 Prophylaxis South Africa (COVER HCW) (COVER)

Covid19 | SARS-CoV Infection

South Africa

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