Search clinical trials for: Spironolactone Tablets

Total 6830 results

Tasly Pharmaceutical Group Co., Ltd

Completed

Study of Jitongning Tablet to Treat Spondyloarthritis

Spondyloarthritis

China
Steno Diabetes Center Copenhagen

Unknown

A Crossover Study With Hexalacton in Patients With Type 1 Diabetes and Microalbuminuria

Diabetes Mellitus | Blood Pressure | Nephropathy
Medical University of South Carolina

Withdrawn

Spironolactone for the Treatment of Melasma

Melasma

United States
Yiling Pharmaceutical Inc.

Completed

A Single-dose Study to Investigate the Tolerance and Pharmacokinetics of Finamine Tablets in China

Parkinson Disease

China
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease (ACHIEVE)

Endstage Renal Disease

Canada, Australia, United Kingdom, New Zealand, Malaysia, Brazil, India, Philippines, Uruguay, Ecuador
The National Institutes of Pharmaceutical R&D Co...

Completed

A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects

Idiopathic Pulmonary Fibrosis

United States
Sunshine Lake Pharma Co., Ltd.

Completed

The Tolerability , Pharmacokinetics and Pharmacodynamics Study of HEC96719 Tablets in Healthy Adult Subjects

Nonalcoholic Steatohepatitis (NASH)

China
Atridia Pty Ltd.

Completed

A Trial of HRS-7085 Tablet in Healthy Participants With and Without Food Effect.

Inflammatory Bowel Disease

Australia
Harmony Biosciences, LLC

Active, not recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension

Prader-Willi Syndrome

United States
Lexicon Pharmaceuticals

Completed

A Multi-Center Trial to Determine the Safety and Efficacy of LX1033 in Subjects With Diarrhea-Predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States
Dong Wha Pharmaceutical Co. Ltd.

Completed

The Phase I Clinical Study to Evaluate the Pharmacokinetics of Dw1029M in Healthy Male Volunteer

Diabetic Kidney Disease

Korea, Republic of
Pfizer

Completed

A Study to Learn How the Body Processes Spironolactone and Hydrochlorothiazide Film Coated Tablets Manufactured at Two Sites: Viatris and Neolpharma

Healthy Participants

United States
Istanbul University - Cerrahpasa (IUC)

Completed

Spironolactone in Covid-19 Induced ARDS

Respiratory Distress Syndrome, Adult

Turkey
National University Hospital, Singapore
University of Otago

Unknown

Mineralocorticoid Antagonism to Stop Progression of Atrial Fibrillation (MONITOR-AF) Study

Atrial Fibrillation

Singapore
Rigshospitalet, Denmark

Completed

The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy.

Hyponatremia | Metabolic Bone Disease

Denmark
Paratek Pharmaceuticals Inc

Active, not recruiting

Oral Omadacycline vs. Placebo in Adults With NTM Pulmonary Disease Caused by Mycobacterium Abscessus Complex (MABc)

Mycobacterium Infections, Nontuberculous | Nontuberculous Mycobacterial Lung Disease | Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection

United States
ACS Biomarker
London School of Hygiene and Tropical Medicine; Institut National de la Santé...

Completed

Bioprofiling Response to Mineralocorticoid Receptor Antagonists for the Prevention of Heart Failure (Homage)

Heart Failure

United Kingdom, France, Netherlands, Germany, Ireland, Italy
Professor Fernando Figueira Integral Medicine Institute
Federal University of São Paulo

Completed

Prevention of the Progression of Coronary Calcification With Use of Spironolactone in Peritoneal Dialysis Patients

Coronary Artery Calcification | Vascular Calcification

Brazil
Sinew Pharma Inc.

Completed

Phase I Pharmacokinetic Study of HUYPS-1 in Healthy Volunteers

Nonalcoholic Steatohepatitis

Taiwan
Medical University of South Carolina

Withdrawn

Spironolactone for Hidradenitis Suppurativa

Hidradenitis Suppurativa
Hansoh BioMedical R&D Company

Not yet recruiting

A Study to Find the Best Dose of HS-10384 to Treat Vasomotor Symptoms in Postmenopausal Women

Vasomotor Symptoms

China
Otsuka Pharmaceutical Co., Ltd.

Completed

A Clinical Pharmacology Trial of Brexpiprazole Once-weekly (QW) Formulation Administered as Single and Multiple Oral Doses

Schizophrenia

Japan
Valenta Pharm JSC

Recruiting

Safety, Tolerability and Pharmacokinetics of 4-MUST, Tablets, 128 mg (Valenta Pharm JSC) During Single and Multiple Oral Administration in Healthy Volunteers

Cholecystitis

Russian Federation
Fulcrum Therapeutics

Completed

Relative Bioavailability and Food Effect Study of Losmapimod 15 mg Tablets

Healthy Adult Subjects

United States
Overseas Pharmaceuticals, Ltd.
GX pharma technology (beijing) Co., Ltd

Active, not recruiting

An Open Label, Balanced, Randomized, 3×3 Latin Square Design Comparing of Brivaracetam Sustained-release Tablets and Brivaracetam Tablets in the Oral Comparative Pharmacokinetic(PK) Study in Chinese Healthy Adult Subjects Under Fasting Conditions.

Partial Seizure

China
CMP Development, LLC

Completed

Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)

Drug Drug Interaction

India
Columbia University

Completed

Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance

Heart Failure

United States
Asan Medical Center

Completed

Pilot Study on Withdrawal of Spironolactone Among Heart Failure With Improved Ejection Fraction

Heart Failure

Korea, Republic of
Vaxart

Completed

Dose-Ranging Trial of Safety & Immunogenicity of an Oral Adenoviral-Vector Based RSV Vaccine (VXA-RSV-f)

Respiratory Syncytial Virus (RSV)

United States
China National Center for Cardiovascular Diseases
Peking University First Hospital; Beijing Children's Hospital

Recruiting

Study of Drug Therapy for Pediatric Heart Failure

Heart Failure Congenital

China
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Strategies in Improving Left Ventricular Function After Mitral Repair

Congenital Mitral Insufficiency

China
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Treatment Therapy for Pediatric Mitral Regurgitation

Congenital Mitral Insufficiency

China
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Sarecycline in Patients With Acute Ischemic Stroke After Reperfusion Therapy (ESPRIT)

Ischemic Stroke, Acute

China
Yonsei University

Withdrawn

A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1)

Congestive Heart Failure
Damanhour University

Completed

Ivabradine in Patients With Congestive Heart Failure

Congestive Heart Failure

Egypt
Instituto Nacional de Ciencias Medicas y Nutricion...

Terminated

Use of Spironolactone for the Prevention of Electrolyte Abnormalities in Patients Treated With Amphotericin B

Patients With Fungic Infections

Mexico
University of California, Los Angeles

Recruiting

Metformin Treatment in Progressive Multiple Sclerosis

Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United States
Vaxart

Completed

Safety & Immunogenicity Study of Ad5 Based Oral Norovirus Vaccines (VXA-NVV-103)

Norovirus Infection

United States
Ultragenyx Pharmaceutical Inc

Completed

Safety and Pharmacokinetics of Sialic Acid Tables in Patients With Hereditary Inclusion Body Myopathy (HIBM)

Hereditary Inclusion Body Myopathy (HIBM)

United States
Stallergenes Greer

Completed

Dose Ranging Study of SLIT Tablets of House Dust Mite Allergen Extracts (HDM) in Adults With HDM-associated Allergic Asthma

Asthma | House Dust Mite Allergy

France, Germany, Poland
Assistance Publique - Hôpitaux de Paris
Société de Dermatologie Française

Completed

Interest of Topical Spironolactone's Administration to Prevent Corticoid-induced Epidermal Atrophy (SPIREPI)

Cutaneous Atrophy Due to Corticosteroids

France
Bayer

Completed

Study of Finerenone to Investigate a Paediatric Formulation in Healthy Male Volunteers

Pharmacokinetics

Germany
State University of New York - Upstate Medical...

Withdrawn

Spironolactone Safety in Dialysis Patients

End Stage Renal Disease | Congestive Heart Failure

United States
Hebei Medical University

Terminated

Larger Dose of Spironolactone for the Treatment of Patients With Nonischemic Cardiomyopathy

Heart Failure, Congestive

China
US Department of Veterans Affairs

Completed

Spironolactone for Reducing Proteinuria in Diabetic Nephropathy

Diabetic Nephropathy

United States
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Recruiting

Cilostazol Dexborneol Versus Placebo for Microcirculation Dysfunction After Reperfusion Therapy in Patients With Acute Ischemic Stroke With Large Vessel Occlusion (CRYSTAL)

Acute Ischemic Stroke | Large Vessel Occlusion | Reperfusion

China
Yale University
American Heart Association

Recruiting

Regulating Blood Pressure During Recovery From Intracerebral Hemorrhage and Ischemic Stroke (REDUCE)

Ischemic Stroke | Intracerebral Hemorrhage | Spironolactone

United States
Emory University

Completed

Spironolactone in Patients With Single Ventricle Heart

Congenital Disorders

United States
Instituto Nacional de Cardiologia Ignacio Chavez

Suspended

Spironolactone and Prevention of Calcineurin Inhibitor Toxicity in Kidney Transplant Recipients

Kidney Transplant

Mexico
Instituto Nacional de Cardiologia Ignacio Chavez

Completed

Spironolactone and Prevention of Peritoneal Fibrosis in Peritoneal Dialysis

End Stage Renal Disease

Mexico

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