Search clinical trials for: substance P

Total 12367 results

Massachusetts General Hospital

Not yet recruiting

Pragmatic Amiodarone Trial to Reduce Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery (PATRONUS)

Atrial Fibrillation | Surgery, Cardiac
Groupe Hospitalier Pitie-Salpetriere

Completed

Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias (AMIRA)

Atrial Fibrillation | Atrial Tachycardia
Prism Pharmaceuticals

Withdrawn

A Randomized, Placebo-Controlled, Double-Blind, Double Dummy Trial To Determine The Relative Effect Of Pm101 Versus Placebo And Amiodarone IV On Blood Pressure In Subjects With Stable Congestive Heart Failure

Blood Pressure
Texas Cardiac Arrhythmia Research Foundation
Stanford University; Case Western Reserve University; University of Kansas; California... and other collaborators

Completed

Effect of Amiodarone on the Procedure Outcome in Long-standing Persistent Atrial Fibrillation Undergoing Pulmonary Vein Antral Isolation (SPECULATE)

Atrial Fibrillation

United States
University of Virginia
Rutgers University; Haydom Lutheran Hospital

Not yet recruiting

Precision Rifampin Trial for Personalized Dosing (P-RIF)

Tuberculosis
Hospital Universitari Vall d'Hebron Research Institute
Radboud University Medical Center; University Medical Center Groningen; Centro... and other collaborators

Not yet recruiting

Rifampicin at High Dose for Difficult-to-Treat Tuberculosis (RIAlta)

Tuberculosis

Spain, Netherlands, Paraguay, Portugal
Suzhou Yabao Pharmaceutical R&D Co., Ltd.

Completed

A Drug Interaction Study of SY-004 Capsules in Healthy Subjects

Type 2 Diabetes

China
Pfizer

Completed

Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600

Healthy Volunteers

Belgium
Hospices Civils de Lyon

Completed

Staphylococcal Acute Post-Operative PJI Treated With 'DAIR' And Impact Of Rifampin (IPASTAPH)

Bone and Joint Infection | Antibiotic Resistant Staphylococcus Aureus Infection

France
Idorsia Pharmaceuticals Ltd.

Completed

A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of Clazosentan

Healthy Subjects

Netherlands
Johns Hopkins University
University of Cape Town Lung Institute; University of Cape Town

Completed

Study of Daily Rifapentine for Pulmonary Tuberculosis

Tuberculosis

South Africa
PTC Therapeutics

Completed

Effects of Rifampin on the Pharmacokinetics of Ataluren

Healthy

Canada
Boehringer Ingelheim

Completed

DDI Strong CYP3A4 Inducer

Healthy

Germany
Drexel University

Completed

Immune Activation and Drug Absorption in HIV-Infected Patients

HIV Infection

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C215: A Clinical Trial in Treatment Naive HIV-subjects Patients Comparing TMC278 to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors

HIV Infections | HIV-1

United States, France, United Kingdom, China, Belgium, Germany, Spain, Chile, Mexico, Portugal, Costa Rica, Panama, South Africa, Canada, Brazil, Puerto Rico, Russian Federation, Thailand, Australia, India
Bayer

Completed

Effect of Rifampin on the Pharmacokinetics of BAY73-4506

Neoplasms

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
All India Institute of Medical Sciences, New Delhi
National AIDS Control Organisation

Completed

Efficacy and Safety of Concomitant Use of Nevirapine and Rifampicin With HIV-TB ("NVP")

HIV/TB Co-infection

India
University of Oulu

Completed

Effects of Pregnane X Receptor (PXR) Activation on Human Glucose, Lipid and Hormone Homeostasis (Rifa-2)

Glucose Metabolism

Finland
Centers for Disease Control and Prevention

Completed

High Dose Rifapentine Pharmacokinetics, Tolerability and Safety Dosage Rifapentine for Treatment of Tuberculosis (TBTC-29PK)

Smear Positive, Pan-sensitive, Pulmonary Tuberculosis

United States, South Africa, Uganda
Mahidol University

Unknown

Colistin Plus Rifampicin in MDR P. Aeruginosa and A. Baumanii

Drug Safety

Thailand
University of Oulu

Completed

Pregnane X Receptor (PXR) Agonist Rifampicin Effects on Glucose, Lipid and Hormone Homeostasis

Glucose Tolerance

Finland
Glaxo Wellcome

Completed

Safety and Effectiveness of Lamivudine When Given Once a Day Versus Twice a Day in Combination With Other Anti-HIV Drugs in HIV-Infected Adults Who Have Never Received Anti-HIV Drugs

HIV Infections

United States, Canada, Argentina, Brazil, Puerto Rico
Dupont Merck

Completed

A Study of Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Leiden University Medical Center
Radboud University Medical Center; University Medical Center Groningen; Erasmus... and other collaborators

Recruiting

Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection (RiCOTTA)

Prosthetic-joint Infection | Infection Hip | Infection; Knee, Joint

Netherlands
Nanjing Sanhome Pharmaceutical, Co., Ltd.

Not yet recruiting

The Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SH-1028

Healthy Male Volunteers

China
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Safety, Tolerability, and Blood Levels of Ritonavir-Boosted Atazanavir and Rifampin When Taken Together in HIV Uninfected Adults

HIV Infections | Tuberculosis

United States
Ascletis Pharmaceuticals Co., Ltd.

Completed

Study to Evaluate the Effects of Itraconazole and Rifampin on the Pharmacokinetics of ASC40 in Healthy Subjects

Healthy

China
Odonate Therapeutics, Inc.

Terminated

The Effect of Tesetaxel on the QTc Interval and the Effect of Food, Itraconazole, and Rifampin on Tesetaxel Pharmacokinetics in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Bayer

Completed

COPANLISIB (BAY80-6946) Drug-drug Interaction and Cardiovascular Safety Study in Advanced Solid Tumor and Non-Hodgkin's Lymphoma Patients

Medical Oncology

Canada, United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Itraconazole and Rifampicin on the Single-Dose Pharmacokinetics of JNJ-53718678 in Healthy Adults

Healthy

United States
Vanderbilt University

Completed

Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis (CLEAR Lung)

Pulmonary Sarcoidosis | Lung Function

United States
LG Life Sciences

Completed

Pharmacokinetic Drug Interaction Study in Healthy Male Subjects

Healthy Male Volunteers

Korea, Republic of
Sanofi

Terminated

LEVOS - Levofloxacin and Rifampicin Therapy in the Treatment of OsteoArticular Prothethic Infection

Infection

France
Kevin W Hatton, MD, PhD

Terminated

Repeated Amiodarone Dosing In Cardiac surgicaL Procedures (RADICAL)

Atrial Fibrillation

United States
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Terminated

Comparison of Treatment of Atrial Fibrillation (AF) Between Surgical Ultrasonic Technology or Drug Therapy for Patients With AF Requiring Mitral Valve Surgery (EPICAF)

Atrial Fibrillation | Mitral Valvulopathy

France
Aarhus University Hospital

Unknown

Amiodarone Prophylaxis for Atrial Fibrillation in Patients Undergoing Surgery for Lung Cancer (PASCART)

Atrial Fibrillation

Denmark
University of Aarhus

Completed

Reduction of Atrial Fibrillation Study in Patients Undergoing Coronary Artery Bypass Grafting. (RASCABG 1 Study)

Atrial Fibrillation | Coronary Artery Bypass Grafting

Denmark
University of California, San Francisco

Withdrawn

Interplay Between Organic Anion Transporting Polypeptide (OATP) Transporters Transporters and CYP2C9 in Glyburide Pharmacokinetics (PK)

Healthy
Institute of Tropical Medicine, Belgium

Recruiting

Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (BE-PEOPLE P3)

Leprosy

Comoros
Institut Bergonié

Completed

Phase I Dose Escalation Trial of Efavirenz in Solid Tumours or Non-Hodgkin Lymphoma in Therapeutic Failure. (ESCALE)

Non-Hodgkin's Lymphoma | Solid Tumors

France
Janssen Research & Development, LLC

Completed

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Healthy Han Chinese, Korean, Japanese, and Caucasian Participants and the Effects of Rifampin on the Pharmacokinetics of Intranasally Administered Esketamine

Healthy

United States
Millennium Pharmaceuticals, Inc.

Completed

Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib

Lymphoma | Solid Tumors

United States
Dong-Min Kim

Completed

Controlled Trial: 5-day Course of Rifampin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus

Scrub Typhus

Korea, Republic of
Eli Lilly and Company

Completed

A Study of Evacetrapib and Rifampin in Healthy Participants

Healthy Volunteers

United States
Michael Hoelscher
German Federal Ministry of Education and Research; ANRS, Emerging Infectious... and other collaborators

Completed

A Trial to Confirm a Sustained Virological Suppression Defined as HIV-RNA <50 Copies/ml of 3 Different Doses of Fozivudine in Context to a Standard Zidovudine Based Antiretroviral Therapy Regimen (FATI-01)

HIV-1 Infection

Côte D'Ivoire, Tanzania
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

A Dose Ranging Trial of GSK1349572 and 2 NRTI in HIV-1 Infected, Therapy Naive Subjects (ING112276)

Infection, Human Immunodeficiency Virus

United States, Spain, France, Germany, Italy, Russian Federation
AbbVie

Completed

A Study to Assess the Effect of Rifampin on the Metabolism of Navitoclax

Solid Tumors | Lymphoma, Including Chronic Lymphocytic Leukemia
Laboratorio Elea Phoenix S.A.

Completed

Bioequivalence Study of Two Formulatiosns With the Asscociaton of Efavirenz, Emtricitabine and Tenofovir

Healthy

Argentina
Region Skane

Completed

MESS-study MRSA Eradication Study Skåne (MESS)

Throatcarriers of MRSA

Sweden

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