Search clinical trials for: Sympatholytics

Total 728 results

University Hospital, Montpellier

Unknown

Neonatal Spinal Anesthesia: Effects of the Addition of Clonidine

Spinal Anesthesia | Neonates

France
CHU de Charleroi

Completed

The Effects of Clonidine on the Diuretic Response in Cirrhotic Patients

Ascitic Cirrhosis | Hyperactivation of Sympathetic Nervous System

Belgium
Deventer Ziekenhuis

Not yet recruiting

The Effect of Clonidine-enhanced Sedation on Delirium in Ventilated Critically Ill Patients (CATAPRES)

Delirium

Netherlands
University of Calgary
Vanderbilt University

Active, not recruiting

Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects

Vasovagal Syncope

Canada
Region Skane
University of Colorado, Denver; Karolinska Institutet; Lund University; The Swedish... and other collaborators

Completed

Clonidine for Analgesia to Preterm Infants During Neonatal Intensive Care

Analgesia | Hypnotics and Sedatives | Intensive Care, Neonatal

Sweden
Medical College of Wisconsin
NorthShore University HealthSystem; Case Western Reserve University

Completed

Interstitial Cystitis: Examination of the Central Autonomic Network (ICECAN)

Myofascial Pelvic Pain | Interstitial Cystitis/Painful Bladder Syndrome

United States
Weill Medical College of Cornell University

Terminated

Feasibility of Administering Clonidine as a Pharmacological Challenge in Imaging Studies (a2a Agonist)

Cancer | Neuro-Degenerative Disease

United States
The University of Texas Medical Branch, Galveston
Shriners Hospitals for Children

Terminated

Propranolol in Severely Burned Children

Burn

United States
Hospices Civils de Lyon

Completed

EEG and Pharmacological Exploration of Executive Dysfunctions Induced by STN-DBS in PD (EEGDBSNAd)

Parkinson Disease

France
University of California, Los Angeles
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Using Clonidine to Improve Leg Weakness in People With Heart Failure

Heart Failure

United States
Bright Future Pharmaceuticals Factory O/B Bright...
Chinese University of Hong Kong

Completed

Clinical Bioequivalence Study on Two Methyldopa Tablet 250mg Formulations

Healthy

Hong Kong
Professor Fernando Figueira Integral Medicine Institute

Completed

Use of Intraoperative Clonidine for Prevention of Postoperative Agitation in Pedriatic Anesthesia With Sevoflurane.

Is an Only Child

Brazil
BioDelivery Sciences International

Completed

A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathy

Diabetes | Painful Diabetic Neuropathy

United States
Ohio State University
Autism Treatment Network; Autism Intervention Research Network on Physical...

Withdrawn

Clonidine for Sleep Disturbances in Children With Autism Spectrum Disorder

Autism Spectrum Disorder

United States
The Rogosin Institute

Terminated

Combined Renin Inhibition/Beta-blockade

Hypertension

United States
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Comparison of Bisoprolol With Metoprolol Succinate Sustained-release on Heart Rate and Blood Pressure in Hypertensive Patients (CREATIVE)

Hypertension

China
Ruijin Hospital

Completed

Effects of Bisoprolol and Atenolol on Sympathetic Nervous Activity and Central Aortic Pressure in Patients With Essential Hypertension

Untreated Essential Hypertension

China
Federal University of São Paulo

Unknown

Assessment of the Effect of Clonidine for Cataract Surgery

Pain | Arrythmia

Brazil
AstraZeneca

Completed

Reversal of Ventricular Remodeling With Toprol-XL

Heart Failure, Congestive

United States
Region Skane

Recruiting

Comparison Between Blocks or Not in Joint Arthroplasty (BLAST)

Osteoarthritis of the Knee or Hip

Sweden
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Primary Open-angle Glaucoma

China
Genzyme, a Sanofi Company

Completed

Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults

Healthy

United States
Harvey S. Singer
UCB Pharma

Completed

Comparison of Keppra and Clonidine in the Treatment of Tics

Tourette Syndrome | Tic Disorders

United States
Sollis Therapeutics, Inc.

Terminated

Sciatica Epidural Radiculopathy Experimental New Interventional TherapY Clonidine Micropellet (SERENITY CM)

Lumbosacral Radiculopathy

United States
University Hospital, Motol

Completed

Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czechia
University of Minnesota
University of Alabama at Birmingham; United States Department of Defense

Terminated

Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United States
Policlinico Casilino ASL RMB

Withdrawn

Effect of Ivabradine and Beta-blockers Combination Versus Beta-blockers Up-titration on Right Ventricular Pacing

Heart Rate Control in ICD Patients With Heart Failure

Italy
National Institute on Drug Abuse (NIDA)

Completed

Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients

Opioid-Related Disorders

United States
Wake Forest University Health Sciences

Terminated

Using Beta Blockers to Treat Mitral Regurgitation (REGURG)

Mitral Regurgitation | Mitral Valve Insufficiency | Heart Disease | Heart Valve Disease

United States
University of Aarhus
Aalborg University Hospital; Aalborg University

Completed

Treating Clozapine-induced Sinustachycardia With Bisoprolol (Biscloz)

Clozapine-induced Sinustachycardia

Denmark
Arcion Therapeutics Inc

Completed

Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

United States
Concordia Pharmaceuticals Inc., Barbados

Completed

Efficacy & Safety of KAPVAY™ Extended-Release in Children & Adolescents With Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder
Assiut University

Not yet recruiting

Clonidine for Infra-orbital Nerve Block During Pediatric Cleft Lip Revision Surgeries

Postoperative Pain
Region Örebro County
Uppsala County Council, Sweden

Recruiting

Clonidine as Pain Relief During ROP Eye Examinations (cloROP)

Retinopathy of Prematurity | Pain, Procedural | Premature Infant Disease

Sweden
Dr. Jean A. Ouellet, MD, FRCSC

Terminated

Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain (RCT)

Scoliosis

Canada
Center for Vascular Pathology, Moscow

Enrolling by invitation

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

Spinal Tumor | Spinal Hemangioma | Beta Blocker Toxicity

Russian Federation
Nationwide Children's Hospital

Withdrawn

Clonidine in Femoral Nerve Block Surgery in Children

Other Reconstructive Surgery

United States
University Health Network, Toronto
Baxter Healthcare Corporation

Terminated

Tight Hemodynamic Control in Patients Who Are Chronically on Metoprolol

Hypertension | Cardiac Disease | Vascular Disease | Angina

Canada
Hannover Medical School
Charite University, Berlin, Germany

Unknown

Cardiovascular Effects of Selective I(f)-Channel Blockade

Postural Orthostatic Tachycardia Syndrome

Germany
Genuine Research Center, Egypt
Nerhadou International for pharmaceutical & Nutraceutical, Egypt

Not yet recruiting

Study of Bisoprolol (Nerkardou - Nerhadou International) 5 and 10 mg Oral Dissolvable Film (ODF) Treatment in Egyptian Patients With Essential Hypertension (BETTER)

Essential Hypertension
Cedars-Sinai Medical Center

Recruiting

Coronary Atherosclerosis T1-Weighted Characterization (CATCH) (CATCH)

Coronary Atherosclerosis

United States
Saniona

Completed

A Study to Examine the Effect of Tesofensine and Metoprolol on the 24-hour Mean Heart Rate

Phase 1

Germany
USWM, LLC (dba US WorldMeds)

Suspended

Randomized, Double-Blind, Placebo-Controlled Pilot Study on the Safety and Effectiveness of LUCEMYRA During an Opioid Taper in Treatment of Withdrawal (TAPER)

Opioid Withdrawal (Disorder)

United States
Rigshospitalet, Denmark

Completed

Does Intraoperative Clonidine Reduce Post Operative Agitation in Children?

Psychomotor Agitation

Denmark
Afshan B. Hameed, M.D.

Withdrawn

A Comparison of Compliance Between Clonidine Patch and Methyldopa for the Treatment of Chronic Hypertension in Pregnancy

Hypertension

United States
Onxeo

Completed

Efficacy and Safety Study of Clonidine Lauriad® to Treat Oral Mucositis

Oral Mucositis

Spain, United States, France, Germany, Hungary, Switzerland
St. Joseph's Health Centre Toronto

Completed

Buprenorphine in the Emergency Department (BED)

Opioid-use Disorder | Opioid Withdrawal
Mensur Salihovic

Completed

Effectiveness of Ultrasound Guided Adductor Canal Block on Chronic Pain in Knee Osteoarthritis

Knee Osteoarthritis

Slovenia
Onxeo
Simbec Research

Completed

Phase 1 PK, Bioavailability, Safety Study of Clonidine MBT w Catapres in Healthy Volunteers

Healthy

United Kingdom
Otsuka Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

Japan

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