Search clinical trials for: TH-302 monotherapy

Total 3100 results

Seoul National University Hospital
Threshold Pharmaceuticals

Completed

Study of TH-302 Monotherapy as Second-line Treatment in Advanced Biliary Tract Cancer

Biliary Tract Cancer

Korea, Republic of
Threshold Pharmaceuticals

Terminated

A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma

Metastatic Melanoma

United States, Canada
Sarcoma Alliance for Research through Collaboration
Threshold Pharmaceuticals

No longer available

SARC021C: A Continuation Study of TH-CR-406/SARC021

Soft Tissue Sarcoma
Threshold Pharmaceuticals

Unknown

A Cardiac Safety Study of TH-302 in Patients With Advanced Solid Tumors

Solid Tumors

United States
Threshold Pharmaceuticals

Completed

A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of TH-302 in Patients With Advanced Solid Tumors

Hypoxia | Tumors

United States
Threshold Pharmaceuticals

Completed

Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | High-risk Myelodysplastic Syndrome | Advanced Myelofibrosis

United States
Herbert Hurwitz, MD
GlaxoSmithKline; National Comprehensive Cancer Network; Threshold Pharmaceuticals

Completed

Dose Escalation Study of Pazopanib Plus TH-302 (PATH)

Solid Tumors

United States
Merck KGaA, Darmstadt, Germany
Threshold Pharmaceuticals

Completed

A Phase 1 TH-302 Mass Balance Trial

Solid Tumor

Germany
Threshold Pharmaceuticals

Completed

Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue Sarcoma

Soft Tissue Sarcoma

United States
Threshold Pharmaceuticals

Unknown

Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors (TH-CR-410)

Gastrointestinal Stromal Tumors | Advanced Renal Cell Carcinoma | Pancreatic Neuroendocrine Tumors

United States
Threshold Pharmaceuticals

Completed

Dose-Escalation Study of TH-302 in Combination With A) Gemcitabine or B) Docetaxel or C) Pemetrexed to Treat Advanced Solid Tumors

Pancreatic Cancer | Non-Small Cell Lung Cancer | Prostate Cancer

United States
Grupo Espanol de Tumores Neuroendocrinos
Pfizer; Threshold Pharmaceuticals

Completed

A Study to Assess the Safety and the Efficacy of the Combination of TH-302 and Sunitinib in Neuroendocrine Pancreatic Tumours

Pancreatic Neoplasms | Neuroendocrine Tumors

Spain
Ding Ma
Shandong University; Huazhong University of Science and Technology; Zhejiang...

Active, not recruiting

The Safety of Ovarian Preservation in Stage IA Endometrial Carcinoma (EC-02)

Endometrial Neoplasms

China
Threshold Pharmaceuticals

Unknown

Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Northwestern University
Brain & Behavior Research Foundation; Neurocentria, Inc.

Completed

Effect of MMFS-202-302 on Cognitive Enhancement in Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
Children's Specialized Hospital
University of Medicine and Dentistry of New Jersey

Completed

The Effect of FES on Children With Spinal Cord Injury

Spinal Cord Injury
Tesu Saglik Teknolojileri A.S.

Recruiting

Efficacy and Safety of Digital Therapeutic in Adults With Prediabetes

PreDiabetes

Turkey
Jinling Hospital, China
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.

Enrolling by invitation

A Study of TH-SC01 for Treating Complex Perianal Fistula in Perianal Crohn's Disease.

Crohn's Disease

China
The University of Texas Health Science Center at...

Completed

Safety and Efficacy Study of TH-302 CNS Penetration in Recurrent High Grade Astrocytoma Following Bevacizumab

HIGH GRADE GLIOMA

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Threshold Pharmaceuticals

Completed

Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery

Kidney Cancer | Liver Cancer

United States
Merck KGaA, Darmstadt, Germany
Threshold Pharmaceuticals

Terminated

A Japanese Trial of TH-302 in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Soft Tissue Sarcoma

Japan
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Study to Test AKR1C3-Activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Refractory T Acute Lymphoblastic Leukemia | Recurrent T Acute Lymphoblastic Leukemia

United States
Rain Oncology Inc

Terminated

Study for Treatment of Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Skin

Metastatic Head-and-neck Squamous-cell Carcinoma

United States, Australia
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
Changhai Hospital

Not yet recruiting

A Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease

Crohn's Disease | Perianal Fistula
PharmAbcine
Merck Sharp & Dohme LLC; Novotech (Australia) Pty Limited

Not yet recruiting

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309 (MarkV-01)

Advanced or Metastatic Solid Tumors

Australia
The University of Texas Health Science Center at...

Completed

TH-302 in Combination With Bevacizumab for Glioblastoma

Glioblastoma

United States
Theraclion

Active, not recruiting

Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)

Breast Fibroadenoma

Bulgaria
Rutgers, The State University of New Jersey
Michael J. Fox Foundation for Parkinson's Research

Completed

Telephone-Based Counseling for Depression in Parkinson's Disease (TH-CBT)

Depression | Parkinson's Disease

United States
Theraclion

Completed

High Intensity Focused Ultrasound (HIFU) to Treat Breast Fibroadenoma

Breast Fibroadenoma

France
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Informatics Framework for Pulmonary Rehabilitation (CHIEF-PR)

COPD

United States
Maastricht Radiation Oncology
Threshold Pharmaceuticals; Zuyderland Medical Centre

Withdrawn

Testing TH-302, in Combination With Preoperative Chemoradiotherapy, in Esophageal Cancer.

Esophageal Cancer
Tel-Aviv Sourasky Medical Center

Unknown

Thermographic Images as an Objective Method for Assessing the Efficacy of Steroidal Epidural Injections

Spinal Stenosis
Hookipa Biotech GmbH

Recruiting

HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer Metastatic

United States
Jinling hospital Nanjing, Jiangsu, China
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.

Recruiting

A Study of TH-SC01 in the Treatment of Radiation-induced Rectal Injury

Rectal Injury

China
Threshold Pharmaceuticals
Sarcoma Alliance for Research through Collaboration (SARC)

Completed

A Trial of TH-302 in Combination With Doxorubicin Versus Doxorubicin Alone to Treat Patients With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma

Soft Tissue Sarcoma

United States, France, Canada, Spain, Germany, Belgium, Poland, Austria, Denmark, Hungary, Israel, Italy, Russian Federation
Swiss Tropical & Public Health Institute
Pevion Biotech Ltd; Mymetics Corporation

Completed

Phase Ib Trial of Two Virosome Formulated Malaria Vaccine Components (PEV 301, PEV 302) in Tanzania (PMAL03)

Falciparum Malaria

Tanzania
Basilea Pharmaceutica

Completed

Derazantinib and Atezolizumab in Patients With Urothelial Cancer (FIDES-02)

Urothelial Carcinoma

United Kingdom, Korea, Republic of, Italy, Canada, France, Spain, Germany, United States, Hungary, Australia, Poland, Switzerland, Czechia, Austria
Threshold Pharmaceuticals
EMD Serono

Terminated

Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

United States, Germany, Spain, Poland, Greece, Czechia, Hungary, Italy, Romania, Russian Federation
University of California, San Francisco

Not yet recruiting

Two-fraction HDR Monotherapy for Localized Prostate Cancer

Prostate Adenocarcinoma | Localized Prostate Carcinoma

United States
VA Office of Research and Development
Department of Veterans Affairs, New Jersey; Rutgers Robert Wood Johnson Medical...

Completed

Telehealth Cognitive Behavioral Therapy for Depression in Parkinson's Disease (PD) (TH-CBT)

Depression | Parkinson's Disease

United States
Xizang Haisco Pharmaceutical Co., Ltd

Recruiting

A Study for HSK39775 in Participants With Solid Tumors

Advanced Solid Tumors

China
Masonic Cancer Center, University of Minnesota

Active, not recruiting

HCW9218 in Select Advanced Solid Tumors

Solid Tumor

United States
Rain Oncology Inc

Terminated

Study for Treatment With TH-4000 (Tarloxotinib) in Epidermal Growth Factor Receptor (EGFR) Mutant, T790M-negative Non-small Cell Lung Cancer (NSCLC) Patients (TH-4000)

NSCLC | Non-small Cell Lung Cancer | Non-squamous NSCLC

United States, Australia
Theraclion

Withdrawn

Efficacy and Safety of High Intensity Focused Ultrasound (HIFU) Device to Treat Secondary Hyperparathyroidism

End Stage Renal Disease | Secondary Hyperparathyroidism | Parathyroid Hyperplasia

Spain, Italy
Peking Union Medical College Hospital

Completed

Pilot Study of Tocilizumab Monotherapy for Active Chronic Periaortitis

Chronic Periaortitis | Tocilizumab Monotherapy

China
Ian Boggero, PhD
National Institute of Dental and Craniofacial Research (NIDCR)

Recruiting

K23- Physical Self Regulation vs Placebo

Temporomandibular Disorder

United States
Groupe d'Etude Therapeutique des Affections Inflammatoires...

Active, not recruiting

Changing the coUrse of cRohn's Disease With an Early Use of Adalimumab (CURE)

CD

France, Belgium
Threshold Pharmaceuticals

Completed

Clinical Trial Testing TH-302 in Combination With Gemcitabine in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma (MAESTRO)

Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma

United States, Germany
PharmAbcine
C&R Research, Inc.

Recruiting

Study to Assess Safety and Tolerability of PMC-403 in Subjects With Neovascular Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration

Korea, Republic of
Second Affiliated Hospital of Guangzhou Medical...

Not yet recruiting

Tirellizumab Combined With Chemotherapy Monotherapy for Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Search clinical trials for: TH-302 monotherapy

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