Search clinical trials for: TSD

Total 1073 results

Ostfold Hospital Trust

Unknown

Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant on Sore Throat and Hemodynamics

Intubation Complication

Norway
Juan Macías

Completed

Changes in Liver Steatosis After Switching to Raltegravir in HIV/HCV Coinfection (STERAL)

HIV Infection | HCV Coinfection

Spain
Fudan University

Not yet recruiting

QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk ER+/HER2- Breast Cancer (QUEEN-Neo)

Neoadjuvant Therapy | Early Breast Cancer | HR+HER2- Breast Cancer
Hoffmann-La Roche

Completed

A Study Evaluating Pertuzumab (Perjeta) Combined With Trastuzumab (Herceptin) and Standard Anthracycline-based Chemotherapy in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced, Inflammatory, or Early-stage Breast Cancer (BERENICE)

Breast Cancer

United States, Canada, Denmark, France, Italy, Poland, Portugal, Spain, United Kingdom, Norway, Germany, Mexico
Sanofi

Completed

Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic Patients (GetGoal-Duo-2)

Type 2 Diabetes

United States, Canada, Chile, Czech Republic, Estonia, France, Germany, Hungary, Italy, Latvia, Lithuania, Mexico, Poland, Romania, Russian Federation, Spain, Ukraine, United Kingdom
Ruijin Hospital
Chugai Pharma China

Completed

Different Anti-Spastic Therapy Strategies After CABG Using Radial Artery Grafts (ASRAB-Pilot)

Coronary Artery Bypass Graft | Radial Artery Grafts | Antispastic Therapy | Pilot Study

China
Organon and Co

Completed

Etoricoxib in the Treatment of Osteoarthritis (MK-0663-007)

Osteoarthritis
NicOx

Completed

To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension (HCT3012-X-112)

Hypertension | Osteoarthritis

United States
Freeman-Sheldon Research Group, Inc.

Terminated

Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions (FSS-QLS)

Depressive Disorder | Craniofacial Abnormalities | Posttraumatic Stress Disorder | Arthrogryposis

United States, Guatemala
October 6 University

Recruiting

Benefits of Trimetazidine in MAFLD Pateints (MAFLD)

Non-Alcoholic Fatty Liver Disease

Egypt
Tianjin Medical University General Hospital

Completed

Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia

Pain | Anesthesia

China
German Breast Group
Celgene Corporation; Amgen

Completed

Denosumab as an add-on Neoadjuvant Treatment (GeparX) (GeparX)

Inflammatory Breast Cancer | HER2 Positive Breast Cancer | Tubular Breast Cancer Stage II | Mucinous Breast Cancer Stage II | Breast Cancer Female NOS | Invasive Ductal Breast Cancer | Tubular Breast Cancer Stage III

Germany
Spanish Breast Cancer Research Group
Pfizer

Completed

Selective Neoadjuvant Treatment According to Immunohistochemical Subtype for HER2 Negative Breast Cancer Patients

Breast Cancer

Spain
Calithera Biosciences, Inc

Completed

Study of the Glutaminase Inhibitor CB-839 in Hematological Tumors

Multiple Myeloma | Non-Hodgkin's Lymphoma (NHL) | Waldenstrom's Macroglobulinemia (WM) | Other B-cell NHL Subtypes, Including WM | T-cell NHL

United States
Washington University School of Medicine
International Headache Society

Recruiting

Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine (IHS)

Migraine

United States
Fondazione Policlinico Universitario Agostino Gemelli...
GlaxoSmithKline

Recruiting

Trial on NIraparib-TSR-042 (Dostarlimab) vs Physician's Choice CHEmotherapy in Recurrent, Ovarian, Fallopian Tube or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment (NItCHE-MITO33)

Ovarian Cancer

Italy
University of Washington
National Cancer Institute (NCI); Imago BioSciences, Inc., a subsidiary of Merck...

Active, not recruiting

Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung Cancer

Extensive Stage Lung Small Cell Carcinoma | Limited Stage Lung Small Cell Carcinoma

United States
Purdue Pharma LP

Completed

The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy Volunteers

ECG Effects

United States
Seattle Children's Hospital
Cystic Fibrosis Foundation

Completed

Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)

Cystic Fibrosis | Chronic Bronchitis

United States
Ohio State University Comprehensive Cancer Center
Cancer and Leukemia Group B

Completed

Omega-3 Fatty Acids in Preventing Joint Symptoms in Patients With Stage I-III Breast Cancer Receiving Anastrozole, Exemestane, or Letrozole

Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Withdrawn

StrataXRT for the Prevention and Treatment of Radiation Dermatitis in Breast Cancer or Head and Neck Cancer Patients

Breast Carcinoma | Head and Neck Carcinoma | Radiation-Induced Dermatitis

United States
VA Ann Arbor Healthcare System
University of Michigan

Completed

Ketamine Infusion for Comorbid PTSD and Chronic Pain

PTSD | Chronic Pain

United States
Pharmacotherapies for Alcohol and Substance Use...
Yale University; United States Department of Defense; VA Connecticut Healthcare... and other collaborators

Completed

Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study

Post Traumatic Stress Disorder (PTSD) | Alcohol Use Disorder (AUD)

United States
Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
St Vincent's Hospital, Sydney
Merck Sharp & Dohme LLC

Completed

Post-prandial Lipid Effects of Raltegravir (RAL) vs Ritonavir -Boosted Darunavir (DRV-r) in Anti-retroviral Therapy (ART)- Naive Adults or Adults Recommencing ART. (ROaR+)

Cardiovascular Disease | HIV

Australia
University College, London
Society for Cardiothoracic Surgery in Great Britain & Ireland; British Congenital...

Unknown

National Congenital Heart Disease Audit

Congenital Heart Disease (CHD)

United Kingdom
Hamad Medical Corporation

Recruiting

Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.

Bronchial Asthma

Qatar
Freeman-Sheldon Research Group, Inc.

Terminated

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome (STOP-FSS)

Craniofacial Abnormalities | Arthrogryposis | Freeman-Sheldon Syndrome | Arthrogryposis Distal Type 2A | Whistling Face Syndrome | Craniocarpotarsal Dysplasia | Craniocarpotarsal Dystrophy | Freeman-Sheldon Syndrome Variant | Sheldon-Hall Syndrome | Arthrogryposis Distal Type 2B | Gordon Syndrome | Arthrogryposis... and other conditions

United States
Sanofi

Completed

Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or CHD Treated With Aspirin and Inadequately Controlled With Metformin Monotherapy or Drug Naive (ACADEMIC)

Type 2 Diabetes Mellitus

China
National Institute of Allergy and Infectious Diseases...
Boehringer Ingelheim

Completed

A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection

HIV Infections | Peripheral Nervous System Disease

United States, Tanzania
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Tongji Hospital; Guangzhou First... and other collaborators

Completed

Allo-HSCT With Alternative Donor in Treatment of Hematologic Malignancy

Chronic Myeloid Leukemia | Acute Leukemia | Myelodysplastic Syndrome

China
University of Oxford

Completed

A Study of the Interaction Between BCG And MenC Immunisation: BAM (BAM)

Immune Response | BCG Infection | Reaction - Vaccine

United Kingdom
Swiss Federal Institute of Technology
University for Development Studies, Tamale, Ghana

Completed

Comparison of Iron Absorption From Extruded FePP-fortified Rice Containing Zinc, Citric Acid/Trisodium Citrate and EDTA (MM_Rice)

Iron Deficiency and/or Anemia

Switzerland, Ghana
University of Sydney
Monash University; Sydney Local Health District

Recruiting

MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder (MPATHY)

Alcohol Dependence | PTSD | Alcohol Use Disorder | Post-traumatic Stress Disorder | Comorbidities and Coexisting Conditions

Australia
Peking University

Not yet recruiting

Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder

Major Depressive Disorder | Chronic Visceral Pain
Global Alliance for TB Drug Development

Completed

A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Hungarian Institute of Cardiology
Semmelweis University

Unknown

Frailty and Cognitive Function Assessment of TAVI Patients

Quality of Life | Aortic Valve Stenosis | Heart Valve Disease

Hungary
Boehringer Ingelheim

Terminated

SPRING: Safety, Efficacy, Pharmacokinetics of tipRanavir/r IN Race/Gender HIV+ Patients Randomized to TDM or SoC

HIV Infections

United States, Argentina, Brazil, Canada, Germany, Italy, Spain
MaineHealth

Completed

Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery

Atrial Fibrillation | Atrial Flutter

United States
Memorial Sloan Kettering Cancer Center

Completed

Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer

Rectal Cancer

United States
QuantumLeap Healthcare Collaborative

Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (I-SPY)

Breast Cancer | Breast Neoplasms | Breast Tumors | HER2-positive Breast Cancer | Angiosarcoma | Locally Advanced Breast Cancer | HER2-negative Breast Cancer | TNBC - Triple-Negative Breast Cancer | Hormone Receptor Positive Tumor | Hormone Receptor Negative Tumor | Early-stage Breast Cancer

United States
Manal El Namrawy

Unknown

Posterior Segment Intrusion Using Miniplates

Orthodontic Anchorage Procedures
Icahn School of Medicine at Mount Sinai

Completed

Aspirin Resistance and Percutaneous Coronary Intervention (PCI) (RESIST)

Stable Angina

United States
Montefiore Medical Center
American Heart Association

Completed

Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain

Coronary Artery Disease | Chest Pain | Angina Pectoris | Angina

United States
National Institute of Oncology, Hungary

Not yet recruiting

Neoadjuvant Treatment of Breast Cancer

Breast Cancer

Hungary
Klein, Jeffrey A., M.D.

Unknown

Tumescent Antibiotic Delivery for Prevention of Surgical Site Infection

Venous Thromboembolism | Surgical Site Infections
Juan A. Arnaiz

Unknown

Safety & Efficacy of Dual Therapy With Raltegravir/Lamivudine (RALAM)

AIDS

Spain
Hellenic Society of Hematology
Sanofi

Not yet recruiting

A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor

Neoplasms | Neoplasms by Histologic Type | Hematologic Diseases | Multiple Myeloma | Neoplasms, Plasma Cell | Paraproteinemias | Blood Protein Disorders | Renal Impairment

Greece
Vrije Universiteit Brussel
Jessa Hospital; Roche Diagnostics

Recruiting

Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment (DECONGEST)

Acute Heart Failure | Diuretics Drug Reactions

Belgium
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States

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