Search clinical trials for: Tapentadol extended release (ER)

Total 777 results

LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.

Healthy

Korea, Republic of
Egalet Ltd

Completed

Efficacy and Safety of Egalet-002 in Patients With Moderate-to-Severe Chronic Low Back Pain

Moderate-to-severe Chronic Low Back Pain

United States
Bausch Health Americas, Inc.

Completed

Randomized,Study of APRISO 375 mg Versus the Approved APRISO 375 mg Capsules in Healthy Male and Female Subjects

Ulcerative Colitis

United States
Abbott

Completed

Pediatric Switch Study for Children and Adolescent Patients With Epilepsy

Pediatric Epilepsy

United States
GlaxoSmithKline

Completed

Mild Alzheimer''s Disease to Assess the of Extended Release Formulation of Rosiglitazone (RSG XR)

Alzheimer's Disease

Germany
Medicis Pharmaceutical Corporation

Completed

A Study to Examine the Effects of Minocycline Extended-Release Tablets on Sperm Production in Human Males.

Human Volunteer

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time

Chronic Pain

United States
Washington University School of Medicine

Terminated

Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children

Spastic Cerebral Palsy

United States
GlaxoSmithKline

Completed

Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy For Subjects With Mild To Moderate Alzheimer's Disease (REFLECT-2)

Alzheimer's Disease

United States, Germany, France, Poland, Portugal, Spain, Canada, Argentina, Chile, India, Greece, Hungary, Italy, Japan, Austria, Brazil, Czechia, Mexico, Switzerland
NRG Oncology
National Cancer Institute (NCI)

Withdrawn

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

Glioblastoma | Anaplastic Astrocytoma | Oligodendroglioma | Supratentorial Glioblastoma
Frederiksberg University Hospital

Completed

Opioid Induced Gait Variability

Opioid Induced Motor Disturbances

Denmark
Merck Sharp & Dohme LLC

Completed

A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102)

Dyslipidemia
Upsher-Smith Laboratories

Completed

Open-label Extension Study to Evaluate the Safety of USL255 in Patients With Refractory Partial-onset Seizures

Epilepsy

Australia, Canada, Poland, United States, Belgium, Spain, Argentina, Israel, India, South Africa, Greece, Russian Federation, Chile, New Zealand, Germany
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets for Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time

Chronic Pain

United States
AbbVie (prior sponsor, Abbott)

Completed

Hydrocodone/Acetaminophen for Acute Pain Following Third Molar Tooth Extraction

Pain

United States
Grünenthal GmbH

Terminated

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability

Pain | Low Back Pain | Chronic Pain | Neuropathic Pain | Nociceptive Pain

Belgium, Czechia, France, Germany, Netherlands, Poland, Spain, Switzerland
Brigham and Women's Hospital

Terminated

Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid

Inflammation | Cardiovascular Disease | Atherosclerosis | Dialysis

United States
NYU Langone Health

Completed

A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall

Attention Deficit Hyperactivity Disorder

United States
UCB Pharma

Completed

A Study to Look at the Efficacy and Safety of Keppra® Extended Release Formulation - XR

Epilepsy

Brazil, Finland, India, Mexico, Russian Federation, South Africa, Ukraine
Massachusetts General Hospital

Completed

Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD

Autism Spectrum Disorder | Attention-deficit/Hyperactivity Disorder

United States
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Mylan Pharmaceuticals Inc

Completed

Food Study of Divalproex Sodium Extended-Release Tablets 500 mg to Depakote ER® Tablets 500 mg

Healthy

United States
Maastricht University Medical Center
Shire

Completed

Extended-release Guanfacine Hydrochloride in Children/Adolescents With Attention-deficit/Hyperactivity (SPD503-315)

Attention Deficit Disorder

Netherlands
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
JPM van Stralen Medicine Professional

Completed

Efficacy of GXR as Adjunctive Therapy With Psycho-stimulant on Executive Function in Children With ADHD

Attention Deficit Hyperactivity Disorder

Canada
Vince & Associates Clinical Research, Inc.
Food and Drug Administration (FDA)

Unknown

A Study in Stable Epilepsy Patients Comparing Brand and Generic Divalproex Sodium Extended Release Tablets (Epilepsy)

Epilepsy

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fed Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fasted Conditions

Healthy

United States
Friends Research Institute, Inc.

Recruiting

Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail

Opioid-use Disorder

United States
Shire

Completed

Tolerability and Efficacy of AM and PM Once Daily Dosing With Extended-release Guanfacine Hydrochloride in Children 6-12 With Attention-Deficit/Hyperactivity Disorder (ADHD) (The ADHD Tempo Study)

Attention-Deficit/Hyperactivity Disorder

United States, Canada
Grünenthal GmbH

Terminated

Tapentadol in Chronic Malignant Tumour Related Pain

Pain | Cancer | Chronic Pain

Bulgaria, Hungary, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia
Brigham and Women's Hospital
Arthritis Foundation

Recruiting

Preventing Injured Knees From osteoArthritis: Severity Outcomes (PIKASO)

Osteoarthritis, Knee | Post-traumatic Osteoarthritis | ACL Tear

United States
Columbia University
Boston University; Johns Hopkins University; University of California, Berkeley; University of Miami and other collaborators

Recruiting

Metformin in Alzheimer's Dementia Prevention (MAP)

Mild Cognitive Impairment

United States
GlaxoSmithKline

Terminated

Effects Of Rosiglitazone (Extended Release Tablets) On Cerebral Glucose Utilisation And Cognition Alzheimers Disease

Alzheimer's Disease

United Kingdom
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin HCl 750 mg XR Under Fasting Conditions

Healthy

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin HCl 750 mg XR Tablets Under Non Fasting Conditions

Healthy

United States
Abbott

Completed

A Study of Extended-Release Hydrocodone/Acetaminophen (Vicodin CR®) in Subjects With Acute Pain Following Bunionectomy

Pain

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Oxybutynin Chloride Extended-Release Tablets 15 mg and Ditropan XL® Tablets 15 mg

Healthy

United States
Novartis Pharmaceuticals

Completed

Open-label Extension Evaluating Methylphenidate Hydrochloride Extended Release in Adults With Attention Deficit/Hyperactivity Disorder

Attention Deficit/Hyperactivity Disorder

Germany, United States, Belgium, Colombia, Denmark, Sweden
The University of Texas Health Science Center,...
The Center for Clinical and Translational Sciences (CCTS) Clinical Research...

Completed

Effects of Antidiabetic Medications on the Postprandial State in Prediabetes

Obesity | Prediabetes

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets

Low Back Pain

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
McGill University Health Centre/Research Institute...
CIHR Canadian HIV Trials Network

Completed

Niacin on Immune Activation : a Proof-of-concept Study

HIV

Canada
Mayo Clinic

Completed

Study to Examine the Effect of Gastric Bypass Surgery on Venlafaxine ER Blood Levels

Roux-en-Y Gastric Bypass | Gastric Bypass | Bariatric Surgery

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Divalproex Sodium Extended-Release Tablets 500 mg to Depakote ER® Tablets 500 mg

Healthy

United States
Weill Medical College of Cornell University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Trial of an Intervention to Improve Metformin Persistence and Adherence (TreatMet)

Tolerance | Metformin Adverse Reaction

United States
Université de Montréal
Labopharm Inc.; MDS Pharma Services

Completed

PK PD of the Enantiomers of Tramadol and O-desmethyltramadol in Elderly and Young Subjects

Pain | Aging
Era's Lucknow Medical College

Completed

Metformin in Overweight Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus

India

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