Search clinical trials for: Tiotropium, fixed dose, solution for oral inhalation

Total 326 results

Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Inhalative Doses of BI 1744 CL in Fixed Dose Combination With Tiotropium Bromide in Healthy Male Volunteers

Healthy
Erik Allen Jensen
University of Florida

Active, not recruiting

Inhaled Tobramycin in BPD

Bronchopulmonary Dysplasia

United States
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BIBW 2948 BS for HandiHaler® in Healthy Male Volunteers

Healthy
Hoffmann-La Roche

Completed

A Study With RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Theravance Biopharma
GlaxoSmithKline; Hammersmith Medicines Research

Completed

A Phase 1 (Ph1), Single Dose (SD), GSK961081 Absorption, Distribution, Metabolism, and Excretion (ADME) Study in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
University Hospital, Ghent

Completed

Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance

Anesthesia

Belgium
AstraZeneca

Completed

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis (GUERANDE)

Acute Viral Bronchiolitis

France
Children's Hospital of Philadelphia

Completed

Hypertonic Saline for Acute Bronchiolitis

Saline Solution, Hypertonic | Bronchiolitis, Viral

United States
Boehringer Ingelheim

Completed

Pharmacokinetic Study in Elderly Patients With Chronic Obstructive Bronchitis (COPD)

Pulmonary Disease, Chronic Obstructive
Apeptico Forschung und Entwicklung GmbH

Recruiting

Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS

ARDS

Austria, Germany
Boehringer Ingelheim

Completed

Observational Study of Adherence to LABA / LAMA in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BIBW 2948 BS in Healthy Male Volunteers

Healthy
Merck Sharp & Dohme LLC

Completed

A Study to Diagnose Lung Cancer by Sputum Cytology (01-312)

Lung Cancer
Orion Corporation, Orion Pharma

Completed

Comparison of Tiotropium Absorption From Tiotropium Easyhaler and Spiriva HandiHaler (TEMPO)

Healthy Volunteers

Finland
Glenmark Specialty S.A.

Completed

Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

United States
Merck Sharp & Dohme LLC

Terminated

Evaluation of the Diagnostic Utility of INS316 in Patients With Interstitial Lung Diseases (01-701)

Interstitial Lung Disease
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BEA 2180 BR in Healthy Male Volunteers

Healthy
Aerie Pharmaceuticals

Completed

Rocklatan® Evaluation

Glaucoma

United States
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
Novartis Pharmaceuticals

Completed

Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis (EAGER)

Cystic Fibrosis

United States, Germany, United Kingdom, Colombia, Spain, France, Netherlands, Israel, Canada, Italy, Chile, Australia, Hungary, Mexico
Novartis Pharmaceuticals

Completed

Indirect Comparison of Tobramycin Solution for Inhalation Versus Aztreonam Lysine for Inhalation in the Treatment of Cystic Fibrosis

Cystic Fibrosis
Boehringer Ingelheim

Completed

12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD

Pulmonary Disease, Chronic Obstructive

Germany, Italy, Switzerland, South Africa
AstraZeneca

Completed

A Clinical Trial in Healthy Volunteers and Patients With Mild Asthma to Investigate a New Medicine (AZD4604) for the Treatment of Asthma

Asthma

United Kingdom
Foresee Pharmaceuticals Co., Ltd.

Completed

Multiple-Dose, Dose-Escalation Study to Evaluate the Safety/Tolerability and Pharmacokinetics of FP-045

Healthy Volunteers

Australia
Boehringer Ingelheim

Completed

12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD

Pulmonary Disease, Chronic Obstructive

Canada, United States
Norgine
Quotient Sciences

Completed

A Pharmacokinetic Study of PLENVU® in Healthy Subjects (PKPU)

Pharmacokinetic

United Kingdom
Anthera Pharmaceuticals

Completed

SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis (SIMPLICITY)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Centrexion Therapeutics

Completed

Safety, Tolerability & Pharmacokinetics Study of CNTX-6016 in Healthy Subjects and Subjects With PDN

Painful Diabetic Neuropathy

United States
AstraZeneca
Quotient Sciences

Completed

An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604

Asthma

United Kingdom
Sun Pharma Advanced Research Company Limited

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SPARC1316

Asthma

United Kingdom
Neupharma Srl
Sintesi Research Srl; Pari Pharma GmbH; Aptuit

Completed

Open-label, Dose-escalation Study to Evaluate the Pharmacokinetics of Inhaled Teicoplanin in Cystic Fibrosis Patients

Cystic Fibrosis

Italy
Boehringer Ingelheim

Completed

Combination of Orally Inhaled BI1744CL/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease ( COPD)

Pulmonary Disease, Chronic Obstructive

United States, Canada, Germany
Basilea Pharmaceutica

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
Lianyungang Kanion Group, Ltd.

Completed

JINZHEN for Treatment of Mild to Moderate COVID-19

COVID-19

United States
Astex Pharmaceuticals, Inc.

Completed

Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndrome | MDS

United States, Canada
Fuji Yakuhin Co., Ltd.

Completed

Study of FYU-981 in Hyperuricemia With or Without Gout

Hyperuricemia

Japan
Taiho Oncology, Inc.

Completed

Study of the Mass Balance of Oral FTD and TPI as Components of TAS-102 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Eisai Inc.

Completed

A Study in Healthy Subjects to Evaluate Bioavailability of 4 Formulations of E5501

Idiopathic Thrombocytopenic Purpura

United Kingdom
Boehringer Ingelheim

Completed

Tiotropium / Respimat One-Year Study

Pulmonary Disease, Chronic Obstructive

Austria, Canada, Spain, United States, Finland, Italy, Russian Federation, United Kingdom, New Zealand, Australia, France, Greece, Ireland, Netherlands, South Africa
Novartis

Completed

Efficacy and Safety of 28 or 56 Day Treatment for Pseudomonas Aeruginosa in Children With Cystic Fibrosis (ELITE)

Cystic Fibrosis
Boehringer Ingelheim

Completed

Efficacy and Safety of Tiotropium and Atrovent in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Rockefeller University
National Institute on Drug Abuse (NIDA)

Completed

Immunologic Effects of HCV Therapy With HARVONI in HCV Genotype 1 Chronically Mono-infected Active and Former IDUs

Hepatitis C

United States
Colorado State University
Institute of Cannabis Research

Completed

The Effect of Cannabidiol in Learning and Memory of Adults

Memory

United States
Boehringer Ingelheim
Pfizer

Completed

Efficacy and Safety of 2 Doses of Tiotropium Respimat Compared to Placebo in Adolescents With Severe Persistent Asthma

Asthma

United States, Argentina, Australia, Bulgaria, Germany, Guatemala, Hungary, Israel, Latvia, Mexico, Philippines, Portugal, South Africa, Ukraine
Boehringer Ingelheim

Completed

Safety, Tolerance, and Pharmacokinetics of BILN 2061 ZW in Healthy Male Subjects, Combined With Preliminary Evaluation of Food Effect

Healthy
Boehringer Ingelheim

Completed

Tiotropium / Respimat One-Year Study

Pulmonary Disease, Chronic Obstructive

Germany, Canada, Spain, Russian Federation, United States, Belgium, France, Greece, Sweden, Norway, Turkey, Australia, Netherlands, United Kingdom
Boehringer Ingelheim

Completed

A Study to Determine the Effect of Tiotropium + Olodaterol Fixed Dose Combination on Exercise Endurance Time During Constant Work Rate Cycle Ergometry Test in COPD

Pulmonary Disease, Chronic Obstructive

United States, Argentina, Canada, Finland, France, Germany, Hungary, Italy, Spain, United Kingdom
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG3970

Healthy

United Kingdom
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Test How the Test Medicine GLPG1972 is Taken up by the Body When Given by Mouth and Into the Vein as an Injection

Healthy

United Kingdom

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