Search clinical trials for: Tocilizumab

Total 499 results

JW Pharmaceutical

Completed

Efficacy and Safety of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of
Peking Union Medical College Hospital

Recruiting

A Prospective Study of Tocilizumab in the Treatment of Idiopathic Retroperitoneal Fibrosis

Idiopathic Retroperitoneal Fibrosis

China
Fundació Institut de Recerca de l'Hospital de la...
Instituto de Salud Carlos III

Recruiting

Clinical Trial of the Use of Tocilizumab for Treatment of SARS-CoV-2 Infection (COVID-19) (TOCOVID)

COVID-19

Spain
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of RO7227166 in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab Administered in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

United States, Belgium, Australia, Denmark, Italy, Spain, France, United Kingdom
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With Polatuzumab Vedotin in B-Cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

United States, Canada, Belgium, Spain, United Kingdom
Hoffmann-La Roche

Active, not recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma

Follicular Lymphoma

United Kingdom, United States, China, France, Spain
Massachusetts General Hospital
Roche-Genentech

Completed

Tocilizumab Plus a Short Prednisone Taper for GCA

Giant Cell Arteritis

United States
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

Rheumatoid Arthritis

Germany, Italy, Spain, United States, France, Sweden, Greece, Russian Federation, Denmark, Finland, Netherlands, Puerto Rico
Hoffmann-La Roche

Completed

A Study Evaluating the Safety and Efficacy of Glofitamab or Mosunetuzumab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and High-Grade Large B-Cell Lymphoma

B-cell Lymphoma

Australia
Sumit Gupta
University of Missouri-Columbia

Completed

Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)

Supracondylar Humerus Fracture | Post Operative Wound Infection

United States
Medical College of Wisconsin

Terminated

Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplant

Lymphoma | Myelodysplastic Syndromes | Acute Leukemia | Chronic Leukemia

United States
King Faisal Specialist Hospital & Research Center
Society of Critical Care Medicine

Unknown

Anti-IL6 and Corticosteroid Monotherapy vs Combination in COVID-19

Critical Illness | Corona Virus Infection | Cytokine Release Syndrome

Saudi Arabia
University of Sao Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection (HEPMAB)

Covid19

Brazil
Hoffmann-La Roche

Completed

Study to Compare the Efficacy of Tocilizumab With or Without Glucocorticoid Discontinuation in Rheumatoid Arthritis Participants

Rheumatoid Arthritis

Serbia, Germany, France, Russian Federation, Italy, Tunisia
MedSIR

Terminated

Checkpoint Blockade in COVID-19 Pandemic (COPERNICO)

COVID-19 | Pneumonia, Viral

Spain
AbbVie

Recruiting

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis. (SELECT-sJIA)

Juvenile Idiopathic Arthritis

United States, Japan, Turkey, Australia, China, Spain, Italy, Germany, Brazil, United Kingdom
Tianjin Medical University General Hospital

Completed

Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders (TANGO)

Neuromyelitis Optica | Neuromyelitis Optica Spectrum Disorders

China
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA)

Giant Cell Arteritis

United States, United Kingdom, Sweden, Belgium, Netherlands, Germany, Spain, Norway, Poland, France, Italy, Canada, Denmark, Portugal
Centre Hospitalier National d'Ophtalmologie des...
Roche Chugai

Recruiting

Efficacy of Tocilizumab for the Treatment of Acute AION Related to GCA (TOCIAION)

Giant Cell Arteritis | Optic Ischaemic Neuropathy

France
Hoffmann-La Roche

Terminated

A Study of Combination Treatment With MabThera (Rituximab) and RoActemra (Tocilizumab) Versus RoActemra in Patients With Rheumatoid Arthritis With an Incomplete Response to Methotrexate

Rheumatoid Arthritis

France, Germany, Switzerland, United Kingdom, Spain, Netherlands, Greece, Poland
Shanghai Zhongshan Hospital

Recruiting

The Registry Study of Takayasu Arteritis in East China

Pregnancy Related | Takayasu Arteritis | Treatment Refusal | Outcome | Mechanisms, Defense

China
Cambridge University Hospitals NHS Foundation Trust

Active, not recruiting

Biologics in Refractory Vasculitis (BIOVAS)

Giant Cell Arteritis | Polyarteritis Nodosa | Takayasu Arteritis | Cryoglobulinemic Vasculitis | IgA Vasculitis | Cogan Syndrome | Relapsing Polychondritis | Cutaneous Polyarteritis Nodosa | Primary Angiitis of Central Nervous System

United Kingdom
Nanjing Medical University

Unknown

Individualized Precise Radiotherapy With the Guidance of Radiosensitivity of Locally Advanced Cervical Cancer (PROGRAMMA)

Cervical Cancer

China
Fujian Cancer Hospital

Recruiting

Oncorine (H101) Combined With Tislelizumab and Chemotherapy in Previously Untreated Advanced Non-small Cell Lung Cancer

Untreated Advanced Non-small Cell Lung Cancer

China
Herlev Hospital
Celgene

Completed

Study of Nab-Paclitaxel and Gemcitabine With or Without Tocilizumab in Pancreatic Cancer Patients (PACTO)

Unresectable Pancreatic Carcinoma

Denmark, Norway
Odense University Hospital
University of Southern Denmark

Unknown

The Diagnostic Value of PET/MRI in Head and Neck Cancer

Head and Neck Neoplasms | Squamous Cell Carcinoma of Head and Neck | Lymph Node Metastases

Denmark
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19 (TOCIDEX)

Coronaviridae Infections | Nidovirales Infections | RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Coronavirus Infection | SARS (Severe Acute Respiratory Syndrome) | Respiratory Tract Disease

French Guiana
University of California, San Diego
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of Atorvastatin and Anakinra in Children With Coronary Artery Abnormalities Secondary to Kawasaki Disease

Kawasaki Disease

United States
Herlev Hospital
Bristol-Myers Squibb

Completed

Checkpoint Inhibitor Induced Colitis and Arthritis -Immunomodulation With IL-6 Blockade and Exploration of Disease Mechanisms (COLAR)

Arthritis | Solid Tumor | Colitis

Denmark
Chinese PLA General Hospital

Unknown

The Comparative Study of Intra-articular Injection of Tocilizumab and Compound Betamethasone

Rheumatoid Arthritis of Knee
Hoffmann-La Roche

Terminated

A Study Evaluating the Safety of Tocilizumab in Addition to Standard of Care Premedication Given Before Obinutuzumab + Chlorambucil in Participants With Untreated B-Cell Chronic Lymphocytic Leukemia (B-CLL) and Comorbidities

B-Cell Chronic Lymphocytic Leukemia

Italy, Spain, Israel, United Kingdom, Latvia
Aetion, Inc.

Active, not recruiting

Methodologies for Observational Studies Comparing Inpatient COVID-19 Treatments

COVID-19

United States
Karolinska University Hospital
Karolinska Institutet

Recruiting

A Study in Patients With COVID-19 and Respiratory Distress Not Requiring Mechanical Ventilation, to Compare Standard-of-care With Anakinra and Tocilizumab Treatment The Immunomodulation-CoV Assessment (ImmCoVA) Study

Covid-19

Sweden
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Combination With an Oral Contraceptive in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular Lymphoma (Celestimo)

Relapsed or Refractory Follicular Lymphoma

United States, Korea, Republic of, Taiwan, China, Spain, United Kingdom, Australia, France, Germany, Japan, Turkey, Brazil, Poland, Ukraine, Italy, Russian Federation
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
Hoffmann-La Roche

Recruiting

A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma (SUNMO)

Non-Hodgkin Lymphoma

United States, Korea, Republic of, China, Mexico, Japan, Brazil, Argentina, Thailand, Canada, Peru, Turkey, Russian Federation, Israel, New Zealand
Lille Catholic University

Recruiting

Abatacept vs Tocilizumab for the Treatment of RA in TNF Alpha Inhibitor Inadequate Responders (SUNSTAR)

Arthritis, Rheumatoid

France
Tianjin Medical University General Hospital

Not yet recruiting

Safety and Efficacy of Tocilizumab in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (TOMATO)

Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

China
National Cancer Institute (NCI)

Completed

A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

Hepatocellular Carcinoma | Cholangiocarcinoma | Bile Duct Cancer | Biliary Tract Neoplasms | Liver Cancer

United States
Shinshu University

Recruiting

Usefulness of Non TNF Usage in RA Patients

Rheumatoid Arthritis

Japan
Academisch Medisch Centrum - Universiteit van Amsterdam...
Noordwest Ziekenhuisgroep

Active, not recruiting

Blood-borne Assessment of Stromal Activation in Esophageal Adenocarcinoma to Guide Tocilizumab Therapy (BASALT)

Oesophageal Adenocarcinoma | Esophageal Adenocarcinoma | Resectable Carcinoma

Netherlands
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Rheumatoid Arthritis

United States, Italy, United Kingdom, Austria, France, Germany, Canada, Argentina, Belgium, Croatia, Bosnia and Herzegovina, Latvia, Spain, Hungary, Czechia, Malaysia, Russian Federation, Serbia, Israel, Poland, Turkey, Netherlands, Greec... and more
National Cancer Institute (NCI)

Completed

Tocilizumab for KSHV-Associated Multicentric Castleman Disease

Castleman Disease | Multicentric Castleman Disease | Giant Lymph Node Hyperplasia

United States
South Valley University

Completed

Toclizumam Versus Dexamethasone in Severe Covid-19 Cases

Pneumonia, Viral

Egypt
University of Zurich
European Foundation for the Study of Diabetes

Completed

Role of Interleukin-6 in Exercise (Exil-6)

Obesity | Diabetes Mellitus, Type 2

Switzerland
Hoffmann-La Roche

Active, not recruiting

An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Non-Hodgkins Lymphoma

Belgium, Spain, Denmark, Italy, United Kingdom, Israel, United States
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States
American Scitech International
Bristol-Myers Squibb; Eli Lilly and Company

Unknown

Study Comparing R-mabHD and a Combination of ABVD in Hodgkin's Disease

Hodgkin's Disease

United States
Christine Ryan
Genentech, Inc.

Recruiting

A Ph 2 Study of Glofitamab Alone or in Combination With Polatuzumab Vedotin or Atezolizumab in Richter's Transformation

Chronic Lymphocytic Leukemia | Richter's Transformation

United States

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