Search clinical trials for: Trypsin Inhibitors

Total 64363 results

Techpool Bio-Pharma Co., Ltd.
Center for ADR Monitoring of Guangdong

Unknown

Post-market Safety Reassessment of Ulinastatin for Injection

Adverse Reaction to Drug

China
Techpool Bio-Pharma Co., Ltd.
The First Affiliated Hospital of Guangzhou Medical University

Unknown

The Safety and Dose Response Relationship of Ulinastatin for Acute Respiratory Distress Syndrome(ARDS)

Acute Respiratory Distress Syndrome

China
Peking Union Medical College Hospital
Techpool Bio-Pharma Co., Ltd.

Completed

Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China

Sepsis | Septic Shock

China
Techpool Bio-Pharma Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Peking Union... and other collaborators

Suspended

Ulinastatin in Severe Acute Pancreatitis

Pancreatitis

China
Maastricht University

Not yet recruiting

In Vivo Effects of Amylase Trypsin Inhibitors (ATI)

Irritable Bowel Syndrome | Non-Coeliac Wheat Sensitivity (NCWS)
Techpool Bio-Pharma Co., Ltd.
Children's Hospital of Fudan University; Shanghai Children's Medical Center; Guangzhou... and other collaborators

Unknown

Ulinastatin Injection in in Pediatric Patients Undergoing Open Heart Surgery

Congenital Heart Diseases

China
Medical College of Wisconsin

Completed

Gluten and Amylase Trypsin Inhibitors (ATI) Free Diet

Type1diabetes

United States
Institute for Human Genetics and Biochemistry
CSL Behring

Completed

Therapy to Elevate CD4 Counts in HIV-1 Disease

HIV Disease

United States
CSL Behring

Completed

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Emphysema | Alpha1-proteinase Inhibitor Deficiency

Australia, Russian Federation, United States, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden, Canada, Czech Republic
Soroka University Medical Center

Unknown

Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery

Post Cardiac Surgery Systemic Inflammatory Response
Baxalta now part of Shire

Completed

GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study

Alpha1-antitrypsin Deficiency

United States, Canada
John Levine
National Cancer Institute (NCI)

Completed

A Proof of Concept Pilot Trial of Alpha-1-Antitrypsin for Pre-Emption Of Steroid-Refractory Acute GVHD

GVHD | Graft-versus-host-disease

United States
Baxalta now part of Shire

Terminated

Aralast alpha1-proteinase Inhibitor Surveillance Study

Alpha1-antitrypsin Deficiency

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD)

Graft-Versus-Host Disease (GVHD) Acute on Chronic

United States
Jinnah Postgraduate Medical Centre

Recruiting

Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality (MUNI-SEP)

Septic Shock | Severe Sepsis | MODS

Pakistan
Nanfang Hospital of Southern Medical University
Dongguan People's Hospital; Foshan Hospital of Traditional Chinese Medicine; Shenzhen... and other collaborators

Recruiting

Effects of Ulinastatin on Inflammatory Response During ECMO Support (Uli-ECMO)

Inflammatory Response | ECMO

China
Shanghai Zhongshan Hospital

Unknown

Protective Effect in Cardiac Surgery Patients

Cardiac Surgery
Yonsei University

Completed

Effects of Ulinastatin on Myocardial Protection and Blood Loss in Patients Undergoing Aortic Valve Replacement

Abnormal Aortic Valve

Korea, Republic of
Baxalta now part of Shire

Completed

Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor)

Alpha 1-Antitrypsin Deficiency

New Zealand, Australia
Nemours Children's Clinic

Completed

Can Aprotinin Reduce Pancreatitis After Scoliosis Surgery

Pancreatitis

United States
Grifols Therapeutics LLC

Terminated

Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)

COVID-19

United States, Brazil, Chile, Colombia, Mexico
Qin Zhang

Completed

Ulinastatin Improves Post-Cardiac Surgery Cognitive Dysfunction

Cardiac Complication

China
Baxalta now part of Shire

Completed

GLASSIA Infusion Rate Study

Healthy Volunteers | Alpha1-antitrypsin Deficiency

United States
KU Leuven
University Ghent; Vrije Universiteit Brussel; Universiteit Antwerpen; Université...

Terminated

The DAWN Antivirals Trial for Ambulatory COVID-19 Patients (DAWN)

Covid19 | SARS-CoV Infection

Belgium
University Hospital, Ghent

Recruiting

The Potential of Oral Camostat in Early COVID-19 Disease in an Ambulatory Setting to Reduce Viral Load and Disease Burden

Covid19

Belgium
Imperial College London
British Heart Foundation

Completed

Investigation of Leukocyte Trafficking Into Skin Blisters During Cardiopulmonary Bypass

Angina Pectoris | Ischemic Heart Disease

United Kingdom
Rabin Medical Center
Kamada, Ltd.

Completed

Long Term Treatment Effect of the Safety, Tolerability and Efficacy of AAT in Type 1 Diabetes (AAT Extension)

Type 1 Diabetes | Beta Cell Preservation

Israel
Virginia Commonwealth University

Completed

Alpha-1 Anti-Trypsin (AAT) Treatment in Acute Myocardial Infarction (VCU-Alpha1RT)

Acute Myocardial Infarction

United States
Seoul National University Hospital

Not yet recruiting

Camostat Mesylate for Protein-losing Enteropathy After Fontan Operation

Fontan Operation | Protein-Losing Enteropathy | Camostat Mesylate
Stanford University

Completed

COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Master Protocol

Covid19

United States
Stanford University

Terminated

COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Camostat Sub-Protocol (COPPS)

Covid19

United States
Assistance Publique - Hôpitaux de Paris

Terminated

CAMOVID : Evaluation of Efficacy and Safety of Camostat Mesylate for the Treatment of SARS-CoV-2 Infection - COVID-19 in Ambulatory Adult Patients (CAMOVID)

Covid19

France
Yonsei University

Completed

Effect of Ulinastatin on Postoperative Renal Function in Patients Undergoing Robot-assisted Laparoscopic Partial Nephrectomy

Renal Mass

Korea, Republic of
Huashan Hospital

Not yet recruiting

Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome (CURE-SepSIRS)

Sepsis

China
University of Dundee

Recruiting

Bronchiectasis Alpha-1 Augmentation Trial- Modulating Airway Neutrophil Function (BATMAN)

Bronchiectasis Adult

United Kingdom
Baxalta now part of Shire
Arriva Pharmaceuticals, Inc.

Completed

Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency

Alpha1-antitrypsin Deficiency

United States
Kamada, Ltd.

Completed

International Study Evaluating the Safety and Efficacy of Inhaled, Human, Alpha-1 Antitrypsin (AAT) in Alpha-1 Antitrypsin Deficient Patients With Emphysema

Emphysema

United Kingdom, Canada, Denmark, Germany, Ireland, Netherlands, Sweden
Assiut University

Not yet recruiting

Maternal alpha1 Antitrypsin as a Marker of Intrauterine Growth Restriction in Pre-eclamptic Women

Pre-Eclampsia | Intrauterine Growth Restriction | alpha1 Anti-trypsin
University of Florida

Recruiting

The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study (ACT)

Alpha-1 Antitrypsin Deficiency

United States
Instituto Grifols, S.A.

Completed

Study to Evaluate the Safety and Efficacy of Prolastin in Hospitalized Subjects With COVID-19

COVID-19

Spain
Ministry of Health, Saudi Arabia

Unknown

Trial of Alpha One Antitrypsin Inhalation in Treating Patient With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Coronavirus

Saudi Arabia
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
University of Alberta
Shire

Completed

Aralast NP in Islet Transplant

Type 1 Diabetes Mellitus

Canada
Baxalta now part of Shire
Arriva Pharmaceuticals, Inc.

Completed

Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency

Alpha1-antitrypsin Deficiency

United States
Blessing Corporate Services, Inc
Takeda Pharmaceuticals North America, Inc.

Withdrawn

Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in Hospitalized Patients With Pneumonia and COVID-19 Infection

Pneumonia, Viral | Covid19

United States
Shire

Withdrawn

ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study

Chronic Obstructive Pulmonary Disease | Alpha1-antitrypsin Deficiency
Ono Pharmaceutical Co. Ltd

Completed

A Study of FOY-305 in Patients With SARS-Cov-2 Infection (COVID-19)

SARS-CoV-2 Infection (COVID-19)

Japan
Stanford University

Withdrawn

Ulinastatin for the Treatment of COVID-19 in Hospitalized Patients

COVID-19

United States
State University of New York - Upstate Medical...

Completed

Effects of Aprotinin During Cardiac Surgery/Long Term Death Rates

Cardiac Surgery

United States
Dartmouth-Hitchcock Medical Center

Terminated

Phase I Study of Aprotinin in Advanced Breast Cancer

Metastatic Breast Cancer

United States

Search clinical trials for: Trypsin Inhibitors

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