Search clinical trials for: Updacitinib (ABT-494)

Total 4745 results

Peking University
KAEDI

Not yet recruiting

NKG2D/CLDN18.21 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumor

Gastric Cancer | Pancreatic Cancer | Solid Tumor

China
jianming xu
KAEDI

Recruiting

NKG2D/CLDN18.2 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumors

Gastric Cancer | Pancreatic Cancer | Solid Tumor

China
Takeda

Completed

A Study of Different Forms of TAK-994 in Healthy Adults

Healthy Participants

United States
Samsung Medical Center

Completed

A Trial of JX-594 in Refractory Colorectal Carcinoma

Colorectal Carcinoma

Korea, Republic of
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose Study of SRA-444 in Healthy Subjects

Alzheimer Disease

Netherlands
Takeda

Completed

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

Healthy Volunteers

United States
AbbVie

Not yet recruiting

A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic Dermatitis (Sleep Up)

Sleep Disturbance | Atopic Dermatitis
AbbVie

Terminated

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ABT-957 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors

Alzheimer's Disease

United States
AbbVie (prior sponsor, Abbott)
Genentech, Inc.

Completed

Study of ABT-869 in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer (NSCLC)

United States, Canada, France, Singapore, Taiwan
AbbVie

Completed

A Study to Evaluate Chronic Hepatitis C Infection in Adults With Genotype 1a Infection (PEARL-IV)

Chronic Hepatitis C Infection
Kafrelsheikh University

Completed

Ridge Augmentation With Simultaneous Implant Placement Using Bone Blocks With Autogenous Tooth Graft

Implant | Ridge Augmentation | Autogenous Tooth Graft

Egypt
AbbVie

Completed

Study of ABT-333 in Both Healthy Volunteers and Hepatitis C Virus (HCV) + Genotype 1 Infected Subjects

HCV Infection
AbbVie (prior sponsor, Abbott)

Completed

Open Label Continuation Study in Moderate to Severe Psoriasis

Moderate to Severe Plaque Psoriasis

United States, Austria, Belgium, Canada, Denmark, Finland, France, Germany, Greece, Italy, Spain, Sweden, Switzerland, United Kingdom
AbbVie (prior sponsor, Abbott)

Completed

Safety, Tolerability and Efficacy Study of ABT-089 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention-Deficit/Hyperactivity Disorder

United States
Abbott

Completed

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ABT-652 in Subjects With Excessive Daytime Sleepiness

Sleep Disorder

United States
Abbott

Terminated

An Evaluation of the Safety and Efficacy of ABT-925 in Subjects With Acute Exacerbation of Schizophrenia

Schizophrenia

United States, Argentina, Mexico
Abbott
Abbott Japan Co.,Ltd

Completed

A Study of Single Doses of ABT-072 in Japanese Healthy Male Adults

Hepatitis C

Japan
Abbott
Abbott Japan Co.,Ltd

Completed

A Study of Single Dose of ABT-333 in Healthy Male Adults

HCV Infections

Japan
Abbott

Completed

Single and Multiple Dose Evaluation of ABT-072 and to Evaluate the Effect of Food on the Pharmacokinetics of ABT-072

Hepatitis C

United States
Abbott

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of the ABT-333 Tablet

HCV Infection

United States
US Department of Veterans Affairs

Completed

Behavioral Treatments for Chronic Pain

Intractable Pain

United States
Innocrin Pharmaceutical

Completed

A Study to Evaluate Once-Daily Oral VT-464 in Patients With Castration-Resistant Prostate Cancer

Castration-resistant Prostate Cancer | CRPC

United States
Aerpio Therapeutics

Completed

Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD Effects in Male Volunteers

IBD

Canada
More Foundation

Completed

Comparison of Motion and Comfort for Thoracolumbosacral Orthoses - Group 2

Back Injuries

United States
M.D. Anderson Cancer Center

Completed

Study of ABT-751 in Patients With Refractory Hematologic Malignancies

Hematological Malignancies

United States
AbbVie (prior sponsor, Abbott)
Genentech, Inc.

Completed

Phase 2 Study of ABT-869 in Advanced Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma

United States, Canada, Singapore, Taiwan
Abbott

Terminated

A Safety and Tolerability Study of ABT-089 in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention-Deficit/Hyperactivity Disorder

United States
Abbott

Completed

Exploratory Positron Emission Tomography (PET) Study to Evaluate the Effects of ABT-614 on [11C]-(+)-PHNO Binding Potential to D3 Receptors in the Brain

Healthy Volunteers

Canada
Abbott

Completed

A Study to Investigate the Process by Which ABT-614 is Absorbed, Distributed, Metabolized and Eliminated in Humans

Healthy

United States
Abbott

Completed

A Study of ABT-751 in Patients With Colorectal Cancer

Colorectal Cancer

United States
Abbott

Completed

A Study of ABT-751 in Patients With Renal Cell Cancer

Renal Cell Cancer

Canada, United States
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate the Safety and Effect of the Experimental Drugs ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Subjects With Chronic Hepatitis C (PEARL-II)

Chronic Hepatitis C Infection
Abbott

Completed

A Dose-Ranging Study of the Efficacy of ABT-894 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

ADHD | Attention-Deficit/Hyperactivity Disorder

United States
Recursion Pharmaceuticals Inc.

Active, not recruiting

The Symptomatic Cerebral Cavernous Malformation Trial of REC-994 (SYCAMORE)

Cerebral Cavernous Malformation

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in a Single Patient With Partial Lipodystrophy

Obesity | Hypertriglyceridemia

United States
Takeda

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics (PK) of Oral TAK-994 in an Acute Sleep Phase Delay Paradigm in Healthy Male Participants

Healthy Volunteers

United States
Alios Biopharma Inc.

Terminated

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Repeated Dosing Regimens of AL-794 in Healthy Volunteers

Healthy

United Kingdom
Achaogen, Inc.
Department of Health and Human Services

Completed

PK Study of ACHN-490 Injection in Renally Impaired Subjects

Renal Insufficiency
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia

Schizophrenia

United States, Russian Federation, United Kingdom
AbbVie

Terminated

Safety, Tolerability and the Effects on Cerebrospinal Fluid Spectrin Breakdown Product-145 Levels of ABT-957 in Subjects With Mild Alzheimer's Disease and Mild Cognitive Impairment

Mild Cognitive Impairment | Alzheimer's Disease

United States
AbbVie

Completed

A Multiple Dose Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ABT-288 in Stable Subjects With Schizophrenia

Schizophrenia
AbbVie

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Subcutaneous Injections of ABT-122 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Abbott

Completed

Pharmacokinetic Study of ABT-126 in Healthy Volunteers

Healthy Volunteers

United States
Abbott

Completed

A Safety, Tolerability and Pharmacokinetic Study of ABT-102 in Healthy Subjects

Healthy Volunteers

United States
Abbott

Completed

Pharmacokinetic and Exploratory Biomarker Study of ABT-126 in Healthy Volunteers

Healthy

United States
Abbott

Completed

A Study of ABT-072 in Healthy and Hepatitis C Virus Genotype 1-Infected Adults

Hepatitis C

United States
University of Leipzig
Curis, Inc.

Terminated

Treatment of Anemia in Patients With Very Low, Low or Intermediate Risk Myelodysplastic Syndromes With CA-4948 (LUCAS)

Myelodysplastic Syndromes | Anemia

Germany
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

Long Term Extension Trial of Setmelanotide

Obesity Associated With Defects in Leptin-melanocortin Pathway

United States, Netherlands, Canada, Germany, United Kingdom, France, Greece, Spain
Takeda

Terminated

A Study of TAK-994 in Adults With Narcolepsy

Narcolepsy Type 1 (NT 1)

United States, Italy, Finland, Canada, Hungary, Czechia, France, Japan, Korea, Republic of, Spain
Senhwa Biosciences, Inc.

Completed

A Study of Silmitasertib (CX-4945) in Healthy Subject

COVID-19

Taiwan

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