Search clinical trials for: VX-708

Total 1414 results

Effector Therapeutics

Completed

Tomivosertib (eFT-508) in Combination With PD-1/PD-L1 Inhibitor Therapy

Solid Tumors

United States
Takeda

Withdrawn

A Study to Evaluate the Impact of Management Strategies on Gastrointestinal-Related Adverse Events in Participants With Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations Receiving TAK-788

Non-Small Cell Lung Cancer (NSCLC)
ChemRar Research and Development Institute, LLC

Completed

А Dose-finding Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety Disorder

Anxiety Disorder Generalized

Russian Federation
Bausch Health Americas, Inc.

Completed

Study Evaluating the Effects of MOA-728 on Cardiac Repolarization in Healthy Subjects

Healthy

United States
AbbVie

Recruiting

Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States, Korea, Republic of, Israel, Japan, Australia, Spain
Sanaria Inc.
University of Maryland, Baltimore

Terminated

A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI

Malaria | Malaria,Falciparum

United States
Logan College of Chiropractic

Unknown

Electroacupuncture and Laser Therapy on Neck Pain

Chronic Neck Pain

United States
University of Edinburgh
Umeå University

Completed

The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin

Coronary Disease

Sweden
Sage Therapeutics

Completed

A Study to Assess Electrophysiology, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of SAGE-718 Using Ketamine Challenge in Healthy Subjects

Healthy Volunteer

United States
Changhua Christian Hospital

Completed

Comparing the Renal Effect of Dipeptidyl-peptidase 4 Inhibitors and Sulfonylureas

Type 2 Diabetes Mellitus | Proteinuria
Second Affiliated Hospital, School of Medicine,...

Recruiting

Clinical Study of Cord Blood-derived CAR NK Cells Targeting CD19/CD70 in Refractory/Relapsed B-cell Non-Hodgkin Lymphoma

B-cell Non Hodgkin Lymphoma

China
Agendia

Completed

PRospective Study Of MammaPrint in Patients With an Intermediate Recurrence Score (PROMIS)

Hormone Receptor Positive Malignant Neoplasm of Breast

United States
Trius Therapeutics LLC

Completed

A Pharmacokinetics and Safety Study in Subjects With Renal Impairment

Renal Impairment

United States
Centre of Experimental Medicine
Millennium Pharmaceuticals, Inc.

Terminated

A Study of Neoadjuvant TAK-700 and Leuprorelin Acetate Followed by Surgery Versus Surgery Alone (NEPTUNE)

Prostate Cancer

United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs

Extensive Stage Lung Small Cell Carcinoma | Limited Stage Lung Small Cell Carcinoma | Platinum-Resistant Lung Small Cell Carcinoma | Platinum-Sensitive Lung Small Cell Carcinoma | Bladder Small Cell Neuroendocrine Carcinoma | Extrapulmonary Small Cell Neuroendocrine Carcinoma | Recurrent Lung... and other conditions

United States
Scynexis, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment (FURI)

Coccidioidomycosis | Invasive Pulmonary Aspergillosis | Allergic Bronchopulmonary Aspergillosis | Histoplasmosis | Chronic Pulmonary Aspergillosis | Blastomycosis | Invasive Candidiasis | Recurrent Vulvovaginal Candidiasis | Mucocutaneous Candidiasis | Other Emerging Fungi

United States, Spain, United Kingdom, Austria, Pakistan, South Africa, Germany, Netherlands
Sage Therapeutics

Completed

A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

Healthy Volunteer

United States
Scynexis, Inc.

Completed

Efficacy and Safety of Oral Ibrexafungerp (SCY-078) vs. Placebo in Subjects With Acute Vulvovaginal Candidiasis (Vanish 306)

Candida Vulvovaginitis

United States, Bulgaria
MDVI, LLC
MediVector, Inc.

Completed

Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316

Influenza

United States, Russian Federation, Turkey, Spain, Belgium, Hungary, South Africa, Bulgaria, Ukraine, Poland, Netherlands, Australia, New Zealand, Sweden
MDVI, LLC
MediVector, Inc.

Completed

Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults

Influenza

United States, Canada, Brazil, Mexico, Colombia, Argentina, Peru, Puerto Rico, Guatemala, Dominican Republic, El Salvador
University of Southern California
National Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.

Terminated

Orteronel in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

Recurrent Prostate Cancer | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
Brigham and Women's Hospital

Unknown

Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment

Seasonal Affective Disorder

United States
Cukurova University

Completed

Effect of Skin Antisepsis on Phlebitis

Phlebitis

Turkey
Yale University

Completed

Using Capnography to Reduce Hypoxia During Pediatric Sedation

Hypoxia | Hypoventilation

United States
Nihon Pharmaceutical Co., Ltd

Completed

Study of NPF-08 in Patients Who Receive Colonoscopy

Patients Who Receive Colonoscopy

Japan
Orion Corporation, Orion Pharma
PRA Health Sciences

Terminated

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of ODM-108: in Healthy Male Volunteers (FIMTRIP)

Healthy

Netherlands
OsciFlex LLC
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation of the OsciPulse Rapid Cycling Compression Device Effects on Venous Blood Flow

Venous Stasis | Venous Thromboses

United States
Bausch Health Americas, Inc.

Withdrawn

Study Evaluating Oral MOA-728 in Subjects on Methadone Therapy

Methadone-maintenance Subjects

United States
Bausch Health Americas, Inc.

Completed

Comparisons Of The Bioavailability And Pharmacodynamics Of Various Formulations Of MOA-728 In Subjects On Methadone

Metahdone-maintenance Subjects

United States
Bausch Health Americas, Inc.

Completed

Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects

Constipation

United States
Trius Therapeutics LLC

Completed

Pharmacokinetic (PK) Study of Oral and IV TR-701 FA in Adolescent Patients

Bacterial Infection
PhytoHealth Corporation

Completed

A Phase II Clinical Study of PDC-748 in Patients With Acute Cough

Acute Cough

Taiwan
The Medicines Company

Completed

Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy (ABP-700)

Colonoscopy

Netherlands
Breath of Life International Pharma Ltd

Withdrawn

A Study to Evaluate the Safety and Efficacy of BOL-DP-o-08 in Patients With Endometriosis Syndrome.

Endometriosis
enGene, Inc.

Recruiting

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Superficial Bladder Cancer | Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

United States
Hoffmann-La Roche

Completed

A Cross-over Study Examining the Bioequivalence of 3 Test Formulations to a Reference Formulation of Alectinib (RO5424802) in Healthy Volunteers

Healthy Volunteer

United States
Bausch Health Americas, Inc.

Completed

Dose Ranging Study in Healthy Methadone Maintenance Subjects

Adult

United States
Bausch Health Americas, Inc.

Completed

Study Evaluating MOA-728 in Subjects on Stable Methadone Maintenance

Methadone-maintenance Subjects

United States
Trius Therapeutics LLC

Completed

Pulmonary Disposition of TR-700 Following Once-Daily Oral 200 mg

Bacterial Infection

United States
AbbVie

Completed

Assessment of the Safety of ABT-308 in Healthy Volunteers and Subjects With Asthma

Asthma
Amgen

Completed

Long-Term Assessment of Safety and Physical Function With AMG 108 in RA

Rheumatoid Arthritis
Tonix Pharmaceuticals, Inc.

Completed

Phase 1 Single Ascending Dose Safety Study of TNX-201 Capsules in Healthy Volunteers

Healthy
University of Wisconsin, Madison

Recruiting

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic Atrophy (COCO-GA)

Geographic Atrophy | Macular Degeneration, Age Related

United States
Trius Therapeutics LLC

Completed

Food Effects of Single Oral Dose of 600mg TR-701

Healthy

United States
Mark Pomerantz, MD
Merck Sharp & Dohme LLC; Rainier Therapeutics

Terminated

Ph 1B B-701 in Combination With Pembrolizumab in Metastatic Transitional Cell Carcinoma of the Urothelial Tract

Bladder Cancer

United States
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Effectiveness of Alcohol 70º vs Soap on Cord Separation Time and the Complication in the Newborn

Umbilical Cord

Spain
Concentric Analgesics

Completed

Study in Subjects Undergoing Complete Abdominoplasty

Postsurgical Pain

United States
Reata, a wholly owned subsidiary of Biogen

Completed

RTA 408 Capsules in Patients With Melanoma - REVEAL

Melanoma | Unresectable (Stage III) Melanoma | Metastatic (Stage IV) Melanoma

United States
University of Pittsburgh
Alaska Native Tribal Health Consortium

Completed

Fiber to Reduce Colon Cancer in Alaska Native People

Colon Cancer

United States
University of Rochester

Completed

Near InfraRed Fluorescence Using Indocyanine Green and Magnetic Resonance Lymphography of Lymphatic Transport (NIR-ICG MRL)

Rheumatoid Arthritis

United States

Search clinical trials for: VX-708

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