Search clinical trials for: Valsartan/hydrochlorothiazide (HCTZ)

Total 983 results

Novartis

Completed

Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Fixed Dose Combination in Hypertensive Patients Not Controlled by the Free Combination of an Angiotensin Receptor Blocker Plus Hydrochlorothiazide

Hypertension

Switzerland, Germany
Novartis

Completed

Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients

Hypertension

Germany, Switzerland
Boehringer Ingelheim

Completed

Telmisartan Tab Hypertension

Hypertension
University of New Mexico
University of Pittsburgh; Dialysis Clinic, Inc.

Terminated

Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes

Hypertension | Proteinuria | Type II Diabetes

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Telmisartan and HCTZ in Two Experimental Formulations Compared to the Standard Formulation Telmisartan and HCTZ in Healthy Female and Male Subjects

Healthy
Boehringer Ingelheim

Completed

Bioequivalence of Telmisartan/ HCTZ Fixed Dose Combination Compared With Its Monocomponents in Healthy Male Volunteers II

Healthy
AstraZeneca

Completed

Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and Placebo

Hypertension

Russian Federation, Latvia, Romania, Slovakia, Belgium, Malta
Oregon Health and Science University
Oregon Clinical and Translational Research Institute

Completed

A Translational Approach to Gitelman Syndrome

Gitelman Syndrome

United States
GlaxoSmithKline

Completed

Bioequivalence Study Between GSK3542503 Hydrochlorothiazide + Amiloride Hydrochloride 50 mg: 5 mg Tablets and Reference Product in Healthy Adult Participants Under Fasting Conditions

Hypertension

South Africa
Boehringer Ingelheim

Completed

An Observational Study to Investigate the Efficacy, Safety, Tolerability and the Effect on Quality of Life of Telmisartan (Micardis) and Telmisartan With HCTZ (Micardis Plus) in Patients With Hypertension

Hypertension

Korea, Republic of
Forest Laboratories

Completed

Combination of Nebivolol and Valsartan Given as Free Tablets for Stage 1 or Stage 2 Hypertension

Hypertension

United States
Vanderbilt University Medical Center

Completed

Aldosterone and the Metabolic Syndrome

Glucose Metabolism Disorders | Metabolic Diseases | Diabetes Mellitus | Endocrine System Diseases

United States
Novartis

Completed

A Study to Evaluate the Combination of Valsartan and Amlodipine in Hypertensive Patients Not Controlled on Monotherapy

Hypertension

Switzerland
Novartis

Completed

Efficacy and Safety of Valsartan, Hydrochlorothiazide and Amlodipine Combination Therapy in Hypertension

Hypertension

Brazil
Boehringer Ingelheim

Completed

Telmisartan/Hydrochlorothiazide (HCTZ) Fixed Dose Combination Compared to Its Monocomponents in Healthy Subjects

Healthy
Boehringer Ingelheim

Completed

Influence of Food on the Bioavailability of Two Doses of Telmisartan/HCTZ Fixed-dose Combination in Japanese Healthy Male Volunteers

Healthy
GlaxoSmithKline

Completed

A Study To Compare Effects Of GSK189075 In Combination With Either Furosemide Or Hydrochlorothiazide

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

United States
Novartis Pharmaceuticals

Completed

Safety and Tolerability of Valsartan in Children 6 to 17 Years of Age

Hypertension | Chronic Kidney Disease

Colombia, Russian Federation, Singapore, Germany, Guatemala, Korea, Republic of, Finland, Philippines, Romania, Poland
Bristol-Myers Squibb
Sanofi

Completed

Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension

Hypertension

United States, Canada, Germany, Russian Federation, France
Novartis

Completed

Aliskiren HCTZ Compared to Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes Mellitus (ASTRIDE)

Hypertension | Diabetes Mellitus

United States
Novartis

Completed

Antiproteinuric Effect of Valsartan and Lisinopril

Hypertension | Diabetic Nephropathy

Switzerland
Novartis

Completed

Safety and Efficacy of Valsartan Plus Hydrochlorothiazide and Amlodipine in Hypertensive Patients

Hypertension

Taiwan
Novartis

Completed

Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-severe Hypertension

Hypertension

Sweden, United States, Romania, Denmark, Israel, Italy, Germany, Australia, Canada, Latvia, Lithuania, Turkey
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Effects and Safety of Sacubitril/Valsartan on Refractory Hypertension

Resistant Hypertension

China
Chiang Mai University

Unknown

Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study (NEB-HF)

Acute Kidney Injury | Acute Heart Failure

Thailand
Federico II University

Completed

Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Patients With Slight Hypertension and Target Organ Damage

Hypertension | Ventricular Remodeling | Erectile Dysfunctions

Italy
Novartis

Completed

Aliskiren/Amlodipine/Hydrochlorothiazide (HCTZ) Versus Aliskiren/Amlodipine in US Minority Patients With Stage II Systolic Hypertension (ASCENT)

Hypertension

United States
Novartis

Completed

VALENCE: Valsartan Versus Atenolol on Exercise Capacity in Hypertensive Overweight Postmenopausal Women

Hypertension

Switzerland, Germany
Novartis

Completed

Safety and Efficacy of Aliskiren + Hydrochlorothiazide (± Amlodipine 5 mg) in Patients With Moderate Hypertension (AMAZING)

Hypertension

Germany
Profil Institut für Stoffwechselforschung GmbH

Completed

Empagliflozin and Sympathetic Nerve Traffic

Type 2 Diabetes Mellitus

Germany
Boehringer Ingelheim

Completed

Telmisartan80/HCTZ25 Versus Telmisartan80/HCTZ12.5 in Hypertension Not Responding to Telmisartan80/HCTZ12.5

Hypertension

France, Switzerland, Italy, Germany, Hong Kong, Netherlands, South Africa, Spain, Taiwan, Denmark, Sweden, Finland, Ireland, Korea, Republic of, Malaysia, Norway
Novartis Pharmaceuticals

Completed

Blood Pressure Lowering of Aliskiren Hydrochlorothiazide (HCTZ) Versus Amlodipine in Stage 2 Hypertension in African Americans (ATLAAST)

Hypertension

United States
Boehringer Ingelheim

Completed

Trial of Telmisartan 80 mg/HCTZ 12.5 mg and Telmisartan 40 mg/HCTZ 12.5 mg in Patients With Hypertension

Hypertension

Japan
Novartis Pharmaceuticals

Completed

Study of the Safety and Efficacy of LCZ696 on Arterial Stiffness in Elderly Patients With Hypertension

Hypertension

United States, Colombia, Spain, Germany, Taiwan, Russian Federation, Argentina, France, Italy, Korea, Republic of, Japan, Greece
Takeda

Completed

Efficacy of Candesartan on Reducing Blood Pressure in Insulin-Resistant, Obese Patients With Hypertension.

Hypertension | Obesity

Germany
University of Pisa

Unknown

Phthalates Exposure in Type 2 Diabetic Patients and Diuretic Therapy (PURITY)

Glucose Metabolism Disorders | Renal Function Disorder

Italy
Qingdao Central Hospital

Not yet recruiting

Sacubitril/Valsartan Versus Valsartan for Hypertensive Patients With Acute Myocardial Infarction

Myocardial Infarction | Hypertension

China
Organon and Co

Terminated

A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)

Hypertension
The Louis & Rachel Rudin Foundation
Daiichi Sankyo, Inc.

Completed

Renin Profiling in Selection of Initial Antihypertensive Drug

Hypertension

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)

Hypertension | Diabetes Mellitus, Type 2
William Beaumont Hospitals
Novartis Pharmaceuticals

Withdrawn

Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II Diabetics

Hypertension | Diabetes Type 2

United States
University of Florida
Abbott

Completed

INVEST: INternational VErapamil SR Trandolapril STudy

Coronary Artery Disease | Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Action to Control Cardiovascular Risk in Diabetes (ACCORD) (ACCORD)

Cardiovascular Diseases | Coronary Disease | Hypertension | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Atherosclerosis | Hypercholesterolemia

United States, Canada
Damanhour University
Tanta University

Completed

Sacubitril/Valsartan Versus Valsartan in Heart Failure

Heart Failure

Egypt
Ospedale San Raffaele

Unknown

Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT) (PGX-HT)

Hypertension

Italy
TSH Biopharm Corporation Limited

Completed

ADDM Study - Amtrel and Co-Diovan in Type 2 Diabetes Mellitus Hypertension Patients With Microalbuminuria

Hypertension | Diabetes Mellitus, Type 2 | Albuminuria

Taiwan
Universität des Saarlandes

Completed

Study to Evaluate the Influence of Hydrochlorothiazide on Dermal Photosensitivity and DNA Stability - a Pilot Study (HCTox Study)

Photosensitivity

Germany
EMS

Not yet recruiting

Efficacy and Safety of Olmesartan Associated With Chlorthalidone Versus Benicar HCT® in Essential Hypertension Control

Arterial Hypertension
Vanderbilt University Medical Center

Completed

The Effects of Renin Inhibition on Fibrinolytic Balance and Endothelial Function

High Blood Pressure

United States
Yuhan Corporation

Completed

Pharmacokinetic Drug Interaction Between Rosuvastatin and Valsartan

Hypertension | Hyperlipidemia

Korea, Republic of

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