Search clinical trials for: Verubecestat (Part II)

Total 9951 results

AstraZeneca

Completed

AZD1152 in Patients With Advanced Solid Malignancies

Tumors

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or Lymphoma

Tumor or Lymphoma

United States, France, Spain
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Terminated

Clinical Study of Liposomal Mitoxantrone Hydrochloride Injection Combined With Pegaspargase in the Treatment of NKTCL

Extranodal NK/T-cell Lymphoma, Nasal Type

China
Wake Forest University Health Sciences

Completed

Social Determinants of Health in Glioblastoma Population

Glioma | Astrocytoma | Ependymoma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Oligodendroglioma

United States
Daewoong Pharmaceutical Co. LTD.

Terminated

Efficacy and Safety of DWJ1248 in Patients With Mild to Moderate COVID-19 Compared to the Placebo

Mild to Moderate COVID-19

Korea, Republic of
Axalbion SA

Completed

AX-8 Drug Safety, Tolerability and Plasma Levels in Healthy Subjects

Healthy

United Kingdom
pfm medical gmbh

Completed

Post-market Clinical Follow-up of Pfmmedical Ports

Patient Satisfaction | Vascular Access Port

Germany
Akesobio Australia Pty Ltd

Completed

A Study of AK120 (IL-4Rα) in Healthy Subjects and Subjects With Moderate- to- Severe Atopic Dermatitis

Atopic Dermatitis

New Zealand, Australia
CrystalGenomics, Inc.

Completed

CG-549 Tablet Pharmacokinetics Study

Healthy

Netherlands
Bukwang Pharmaceutical

Active, not recruiting

Study in Parkinson's Disease Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components (SHINE)

Parkinson Disease | Dyskinesias

United States
Bilix Co.,Ltd.

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of BX-001N in Healthy Participants

Ischemia-reperfusion Injury

Australia
Bilthoven Biologicals
Serum Institute of India Pvt. Ltd.

Completed

A Clinical Study Comparing Safety and Immunogenicity of bOPV of Bilthoven Biologicals

Immune Response to Oral Polio Vaccine

Bangladesh
Ferring Pharmaceuticals

Recruiting

A Study Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Persons

Inflammatory Gastrointestinal Diseases

Germany
MBX Biosciences

Completed

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects

Healthy

United States
Vertex Pharmaceuticals Incorporated

Terminated

A Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment-Resistant Partial Epilepsy

Epilepsy

United States, Germany
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD2423 Multiple Doses in Healthy Volunteers

Healthy

United Kingdom
Organon and Co

Completed

Etoricoxib in the Treatment of Osteoarthritis (MK-0663-007)

Osteoarthritis
M.D. Anderson Cancer Center

Terminated

Symptom Burden in Patients With Cancer- and Treatment-Related Skin Problems

Skin Cancer

United States
Janssen Research & Development, LLC
Pharmacyclics LLC.

Completed

A Study Combining Ibrutinib With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With CD20-Positive B-Cell Non Hodgkin Lymphoma

CD20-positive B-cell Non-Hodgkin Lymphoma

United States, France
Elpiscience Biopharma, Ltd.

Active, not recruiting

A Study of ES002023 (Anti-CD39 Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumor

United States
AceLink Therapeutics, Inc.
Novotech (Australia) Pty Limited

Completed

To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AL01211 in Healthy Volunteers

Autosomal Dominant Polycystic Kidney

Australia
Philip Morris Products S.A.

Completed

Smoking Research Study

Smoking | Non-smoking

United Kingdom
Novartis Pharmaceuticals

Active, not recruiting

Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD)

Sickle Cell Disease

United States
AstraZeneca

Completed

Single Centre, Double-blind, Single and Multiple Ascending Inhaled Doses of AZD9819 in Healthy Subjects

Healthy Volunteers | Tolerability | Safety

United Kingdom
Universitaire Ziekenhuizen KU Leuven

Recruiting

Trial to Investigate the Benefit of Elective Para-Aortic Radiotherapy (PART) for pN1 Prostate Cancer (PART)

Prostate Cancer

Belgium
NYU Langone Health

Completed

Visible Light Study

Skin Disease | Pigment Disorders

United States
Société des Produits Nestlé (SPN)

Completed

Oral CDX-7108 in Healthy Adults and EPI Subjects

Exocrine Pancreatic Insufficiency

Australia, New Zealand
Washington University School of Medicine

Recruiting

Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas

Astrocytoma | Glioma, Malignant | Oligodendroglioma, Adult

United States
Bausch & Lomb Incorporated

Completed

Study to Explore the Pharmacokinetics and Pharmacodynamics of Epinephrine in Healthy Male and Female Subjects With Different Skin to Muscle Depth (STMD)

Anaphylaxis

Germany
OliPass Corporation

Completed

OLP-1002 is Being Studied in the Treatment of Pain.

Pain

United Kingdom
Xuanzhu Biopharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Trial of XZP-5610 Tablets in Healthy Subjects

Nonalcoholic Steatohepatitis (NASH)

China
Actimed Therapeutics Ltd
Quotient Sciences

Completed

Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV)

Cachexia

United Kingdom
Melbourne Health
AnHeart Therapeutics Inc.; Walter and Eliza Hall Institute of Medical Research

Active, not recruiting

A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma (AB-218-IIT-201)

Glioma

Australia
GlaxoSmithKline

Completed

HuMax-CD20 in Active Rheumatoid Arthritis, Phase I/II

Arthritis, Rheumatoid
Cellid Co., Ltd.

Active, not recruiting

Safety and Immunogenicity of AdCLD-CoV19-1 OMI as a Booster: A SARS-CoV-2 (COVID-19) Preventive Vaccine

COVID-19 | Vaccines

Korea, Republic of
Enanta Pharmaceuticals, Inc

Terminated

A 2 PART STUDY EVALUATING EDP-721 IN HEALTHY SUBJECTS AND EDP-721 IN COMBINATION WITH EDP-514 IN PATIENTS WITH CHRONIC HEPATITIS B VIRUS INFECTION.

Chronic Hepatitis B Virus Infection

New Zealand
Hoffmann-La Roche

Completed

A Two-part, Single-dose, Randomized Study to Evaluate the Safety of Supra-therapeutic Doses of RO7033877 and to Investigate the Effect of RO7033877 on the QTc Interval

Healthy Volunteer

United States
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED) (SPIFD-101)

Fuchs' Corneal Endothelial Dystrophy (FCED)

United States
Linkoeping University
Ostergotland County Council, Sweden; Fibromyalgia foundation

Not yet recruiting

Nutrition Care in Patients Living With Chronic Pain

Overweight and Obesity | Pain, Chronic | Mobile Phone Use | Nutrition Poor
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

A Study of HS-10382 in Patients With Chronic Myeloid Leukemia.

CML, Chronic Phase | CML, Accelerated Phase

China
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

Chronic Kidney Disease

United States
MBX Biosciences
ProSciento, Inc.

Recruiting

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of MBX 1416 in Healthy Subjects

Postbariatric Hypoglycemia

United States
Cara Therapeutics, Inc.

Completed

Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus

Pruritus | Uremic Pruritus

United States
Trevena Inc.

Terminated

A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250

Migraines

United Kingdom
Sun Pharmaceutical Industries Limited

Completed

Efficacy and Safety of Tildrakizumab in the Treatment of Scalp Psoriasis

Scalp Psoriasis

United States, Australia
Bial - Portela C S.A.

Completed

Efficacy and Safety of Eslicarbazepine Acetate as Adjunctive Therapy for Refractory Partial Epilepsy

Partial Epilepsy

Portugal
GlaxoSmithKline

Withdrawn

A Study of GSK2110183 in Subjects With Proteasome Inhibitor Refractory Multiple Myeloma

Cancer

Australia
Centre Oscar Lambret
National Cancer Institute, France

Completed

Hypofractionated Stereotactic Boost in Prostate Cancer (CKNO-PRO)

Cancer

France
Kadmon Corporation, LLC
Quotient Sciences

Completed

A Phase I Study to Evaluate the Taste of Belumosudil Oral Suspensions & Assess Relative Bioavailability

Healthy Volunteers

United Kingdom
Verrica Pharmaceuticals Inc.
Instat Clinical Research; HeartcoR Solutions; Myonex; Vial Health Technology, Inc

Recruiting

Open-Label Proof of Concept Study of VP-315 in Basal Cell Carcinoma

Carcinoma | Skin Cancer | Basal Cell Carcinoma | Cancer of the Skin, Basal Cell | Cancer of the Skin

United States

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