Search clinical trials for: Zonisamide at targeted daily doses of 100-500 mg/day

Total 231 results

Eisai Limited

Terminated

A Study to Evaluate the Safety and Tolerability and Explore the Efficacy of Zonisamide as add-on Therapy in Elderly Patients With Refractory Partial Seizures

Epilepsy

United Kingdom, Germany, Hungary, Switzerland, Italy, Netherlands, Poland
Egyptian Liver Hospital
Wadi El Nil Hospital

Completed

Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of Sofosbuvir Tablet Plus Ribavirin Tablet (Part A) Versus Single Dose (2 Tablets) of EHCV Containing Sofosbuvir, Ribavirin, and Natural Anti-hemolytic (B) in Egyptian Adults With Chronic Genotype 4 HCV Infection

Hepatitis c

Egypt
Gamaleya Research Institute of Epidemiology and...

Not yet recruiting

Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV

Gram-Negative Bacterial Infections | Bacteremia Caused by Gram-Negative Bacteria | Gram Negative Pneumonia
AstraZeneca

Completed

Pharmacokinetics in Adolescents (PEAK)

Asthma

Sweden
Genzyme, a Sanofi Company

Terminated

ZACtima FASlodex Trial in Postmenopausal Advance Breast Cancer Patients Instead of ZACtima FASlodex Trial (ZACFAST)

Breast Cancer

Italy
Haiphong University of Medicine and Pharmacy

Completed

Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection

Chlamydia Trachomatis Infection | Neisseria Gonorrhoeae Infection

Vietnam
Juventas Therapeutics, Inc.

Unknown

Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Ischemic Heart Failure (RETRO-HF)

Ischemic Heart Failure

United States
Mutual Pharmaceutical Company, Inc.

Completed

Fed Bioavailability Study of Zonisamide Capsules

Healthy

United States
Virginia Commonwealth University
GlaxoSmithKline; Puma Biotechnology, Inc.

Recruiting

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer (iNNOVATE)

Ovarian Cancer | Advanced Solid Tumor

United States
Mutual Pharmaceutical Company, Inc.

Completed

Fasting Bioavailability Study of Zonisamide Capsules

Healthy
Galapagos NV

Completed

Investigation of the Pharmacokinetics and Metabolism of GLPG0634 in Healthy Male Subjects

Healthy

United Kingdom
Viriom

Not yet recruiting

Study Evaluating the Efficacy and Safety of AV5080 in Patients With Uncomplicated Influenza

Influenza

Russian Federation
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Zonisamide Capsules 100 mg and Zonegran® Capsules 100 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Zonisamide Capsules 100 mg and Zonegran® Capsules 100 mg

Healthy

United States
Jair Bar, M.D., Ph.D.
Merck Sharp & Dohme LLC

Completed

Anti PD-1 Neo-adjuvant Treatment for NSCLC (MK3475-223)

Non Small Cell Lung Carcinoma | Stage II | Stage I

Israel
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic and Pharmacodynamic Study of Once-Daily and Twice-Daily Dosing With Canagliflozin in Healthy Adult Volunteers

Healthy
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Determine the Antiviral Activity of TMC310911 When Administered With Ritonavir in Treatment-Naive Human Immunodeficiency Virus - Type 1 (HIV-1) Infected Patients

Human Immunodeficiency Virus Type 1

Germany
Dallas VA Medical Center
Otsuka Pharmaceutical Development & Commercialization, Inc.

Unknown

Standard Triple Therapy vs Sequential Therapy in Treatment of H Pylori Infection

Helicobacter Infection

United States
Indonesian Nutrition Association

Recruiting

Bioavailability of Different Formulas Enriched With DHA Using Wet Mixing or Dry Blending Method

Healthy Children

Indonesia
Faculdade de Medicina do ABC

Unknown

Phase II Clinical Trial of Uncaria Tomentosa (Cat´s Claw) in Patients With Advanced Solid Tumors (cat´sclaw)

Solid Tumors

Brazil
CTI BioPharma
PPD

Recruiting

Study to Evaluate the Safety, Tolerability, and PK of Pacritinib

Hepatic Impairment

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study of PVP001, PVP002, and PVP003 in Healthy Adults and PVP001 and PVP002 in Adults With Celiac Disease

Digestive System Disease

United States
Fundacion Clinic per a la Recerca Biomédica

Withdrawn

Pilot Study Evaluate Efficacy of Grazoprevir + Elbasvir for 12 or 16 Weeks in Liver Transplant Recipients. (EGRADICATE)

Liver Transplantation | Hepatitis C
Swiss Federal Institute of Technology

Completed

The Optimization of Bioavailability From Iron Supplements: Study 2

Anemia | Iron Deficiency Anemia | Iron Deficiency

Switzerland
Pfizer

Completed

Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy Participants

HEALTHY

China
Lundbeck Canada Inc.

Completed

Bendamustine Hydrochloride (HCl) in Indolent Non-Hodgkin's Lymphoma That Has Progressed During or Following Treatment With a Rituximab Regimen or Previously Untreated Chronic Lymphocytic Leukemia (BENDACT)

Chronic Lymphocytic Leukemia | Indolent Non-Hodgkin's Lymphoma

Canada
Kadmon Corporation, LLC
Quotient Sciences

Completed

Human Absorption, Distribution and Metabolism Study (hAME) [14C]-KD025 (KD025-108)

Fibrosis | Autoimmune Diseases

United Kingdom
Merck Sharp & Dohme LLC

Completed

Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
VA Office of Research and Development

Completed

Pharmacological Treatment of Generalized Anxiety Disorder in the Elderly (Sert-GAD)

Generalized Anxiety Disorder

United States
ViiV Healthcare
GlaxoSmithKline

Terminated

Dose-finding Study of GSK2248761 in Antiretroviral Therapy-experienced Subjects With NNRTI-resistant HIV Infection (SONNET)

Infection, Human Immunodeficiency Virus

United States, Canada, Italy, Belgium, Romania
Tulane University Health Sciences Center

Completed

Trichomonas Vaginalis Repeat Infections Among HIV Negative Women

Vaginitis Trichomonal or Due to Trichomonas

United States
MediBeacon

Completed

Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

Acute Kidney Injury

United States
University of Aarhus
University of Copenhagen

Completed

Effect of Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans

Muscle Injury

Denmark
Hal Chapman
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Recruiting

Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect

Idiopathic Pulmonary Fibrosis

United States
Mansoura University

Completed

Antioxidants and Zinc Improving Minimal Hepatic Encephalopathy In Truck Drivers; a Pilot Study

Minimal Hepatic Encephalopathy

Egypt
Gilead Sciences

Completed

Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-9669 in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C

United States, Puerto Rico
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Endothelial Modulation for Angiogenic Therapy

Coronary Artery Disease

Canada
Xiayun He, MD

Completed

Reduced Target Delineation and Radiation Doses Chemoradiotherapy for Patients With Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Rambam Health Care Campus
Boehringer Ingelheim

Unknown

Empagliflozin Versus Placebo on the Rate of Arrhythmic Events in Heart Failure Patients (ERA-HF)

Heart Failure | Diabetes Mellitus | Arrythmia
Institut Curie
Hoffmann-La Roche; Ministry of Health, France; Amgen; Pierre Fabre Laboratories

Active, not recruiting

Cranial Radiotherapy or Intensive Chemotherapy With Hematopoietic Stem Cell Rescue for Primary Central Nervous System Lymphoma in Young Patients (PRECIS)

Primary Central Nervous System Lymphoma

France
Eli Lilly and Company
CoLucid Pharmaceuticals

Completed

Lasmiditan Compared to Placebo in the Acute Treatment of Migraine: (SAMURAI)

Acute Migraine

United States
Federico II University

Completed

Platelet Aggregation in Diabetic Patients With Acute Coronary Syndrome Treated With Different Doses of Aspirin (DIABE-ASACS)

Diabetes Mellitus | Acute Coronary Syndrome

Italy
Helwan University

Active, not recruiting

The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients

Post Operative Atrial Fibrillation

Egypt
Merck Sharp & Dohme LLC

Completed

MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)

Type 2 Diabetes Mellitus
University at Buffalo
Kaleida Health

Terminated

Resveratrol in Type2 Diabetes and Obesity

Obesity | Insulin Resistance | Type 2 Diabetes

United States
University of Washington
Cystic Fibrosis Foundation

Completed

A Pharmacokinetic and Safety Study of IV Gallium Nitrate (Ganite) in Cystic Fibrosis Patients

Cystic Fibrosis

United States
Masonic Cancer Center, University of Minnesota

Active, not recruiting

MT2017-45: CAR-T Cell Therapy for Heme Malignancies

Acute Lymphoblastic Leukemia | Large B-cell Lymphoma

United States
The Netherlands Cancer Institute
Roche Pharma AG; Borstkanker Onderzoek Groep

Active, not recruiting

Neoadjuvant Chemotherapy in HER2 Positive Breast Cancer, TRAIN-2 (TRAIN-2)

Breast Cancer | HER2 Positive

Netherlands
University Medical Centre Ljubljana
University of Ljubljana School of Medicine, Slovenia

Completed

Duration of Doxycycline Treatment in EM Patients

Erythema Chronicum Migrans

Slovenia
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)

Head and Neck Neoplasms

Poland, Canada, Brazil, Belgium, Japan, United States, Argentina, Australia, Austria, Chile, Colombia, France, Germany, Hungary, Ireland, Israel, Korea, Republic of, Portugal, Russian Federation, Spain, Switzerland, Taiwan, Ukraine, United...

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