Search clinical trials for: alloreactive CTL

Total 1625 results

Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Cellular Immunotherapy Study for Brain Cancer (alloCTL)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Gliomas | Anaplastic Mixed Glioma | Malignant Meningioma

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS (NKAML)

Adult Acute Myeloid Leukemia in Remission

Italy
Chinese Academy of Medical Sciences, Fuwai Hospital
Peking Union Medical College Hospital; Guangdong Provincial People's Hospital; Tianjin Medical University General Hospital and other collaborators

Unknown

Prognostic Value of CT dynamIc Myocardial Perfusion in Patients With Obstructive Coronary Artery Stenosis (VALIDITY)

CT Perfusion

China
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

EBV CTLs Expressing CD30 Chimeric Receptors For CD 30+ Lymphoma (CARCD30)

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma

United States
Instituto de Investigación Hospital Universitario...

Recruiting

"Phase I / II Study on Infusion of Natural Killer Cells After Haploidentical Transplantation in Pediatric Patients" (PHINK)

High-risk Leukemias

Spain
Kiadis Pharma

Terminated

Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Lymphoma | Myeloid Leukemia | Myeloproliferative Disorders | Multiple Myeloma | Myelodysplastic Syndrome | Lymphoblastic Leukemia

Canada, Netherlands, Germany, Belgium, United States, Italy, United Kingdom
Atara Biotherapeutics

No longer available

Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies

Lymphoproliferative Disorders | Stem Cell Transplant Complications | Epstein-Barr Virus (EBV) Infections | EBV+ Associated Lymphoma | EBV+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD) | Epstein-Barr Viremia | Lymphoma, AIDS-related | Epstein-Barr Virus-associated Lymphoproliferative... and other conditions
Kiadis Pharma

Completed

Dose-ranging Study of a Single Administration of T-cell Add-back Depleted of Host Alloreactive Cells in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Hematologic Diseases | Hematologic Malignancies

Canada
Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Active, not recruiting

Blood T-Cells and EBV Specific CTLs Expressing GD-2 Specific Chimeric T Cell Receptors to Neuroblastoma Patients (NESTLES)

Neuroblastoma

United States
University of Paris 13
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Impact of Nutrition Labels on Consumer Purchasing Intentions

Food Labeling | Choice Behavior

France
Atara Biotherapeutics

Recruiting

Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy (ALLELE)

Lymphoproliferative Disorders | Stem Cell Transplant Complications | Solid Organ Transplant Complications | Allogeneic Hematopoietic Cell Transplant | Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)

United States, Austria, Australia, Belgium, Canada, France, Italy, Spain, United Kingdom
University of Sydney

Unknown

Infection and Tumour Antigen Cellular Therapy (INTACT-WT1)

Leukemia, Myelocytic, Acute

Australia
Beijing Doing Biomedical Co., Ltd.

Unknown

Clinical Safety and Preliminary Efficacy of MUC1-DC-CTL Treatment in Stage IV Gastric Cancer.

Gastric Cancer

China
New York Medical College
Johns Hopkins University; Children's Hospital of Philadelphia; Medical College... and other collaborators

Recruiting

Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

Primary Immune Deficiency Disorder | Viral Infection

United States
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI); The Methodist Hospital Research... and other collaborators

Completed

Administration of Virus-Specific Cytotoxic T-Lymphocytes (LYPTAIST)

Adenovirus Infection

United States
Rigshospitalet, Denmark
Bispebjerg Hospital; Herlev Hospital; Glostrup University Hospital, Copenhagen; Amager Hospital and other collaborators

Completed

CArdiac cT in the Treatment of Acute CHest Pain 2 - Myocardial CT Perfusion (CATCH2)

Coronary Artery Disease

Denmark
Shixiu Wu

Unknown

Combination of Radiation Therapy and Peptide Specific CTL Therapy in Treating Patients With Esophageal Cancer

Digestive System Diseases | Esophageal Neoplasms | Esophageal Diseases

China
M.D. Anderson Cancer Center

Withdrawn

PR1-Specific Cytotoxic T-Lymphocyte Infusion With Recurrent Chronic Myelogenous Leukemia (CML) After Allogeneic Hematopoietic Transplantation

Chronic Myelogenous Leukemia
Atara Biotherapeutics
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center

Completed

Biological Therapy in Treating Patients at High-Risk or With Lymphoma, Lymphoproliferative Disease, or Malignancies

EBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk of Developing a Recurrent EBV Lymphoma

United States
Atara Biotherapeutics

Recruiting

A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases

Lymphoproliferative Disorders | Leiomyosarcoma | Stem Cell Transplant Complications | Solid Organ Transplant Complications | Epstein-Barr Virus (EBV)-Associated Diseases | EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD) | Allogeneic Hematopoietic Cell Transplant | EBV+ Sarcomas | EBV+ Lymphoproliferative... and other conditions

United States, Austria, Belgium, France, Italy, Spain, United Kingdom
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI); The Methodist Hospital Research... and other collaborators

Completed

Cytotoxic T-Lymphocytes for the Prophylaxis of Cytomegalovirus After Allogeneic Stem Cell Transplant (VICTA)

Cytomegalovirus Infections

United States
Queen's University

Completed

Examining the Impact of Blood Flow Restricted Aerobic Exercise on PGC-1α mRNA Expression in Young Healthy Males

Mitochondrial Biogenesis

Canada
Nantes University Hospital

Terminated

Autologous EBV-specific Cytotoxic T Cells for the Treatment of Systemic Lupus Erythematosus (SLE) (LUPUS CTL EBV)

Serologically Active Adult Systemic Lupus Erythematosus

France
Atara Biotherapeutics
Merck Sharp & Dohme LLC

Terminated

Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

Nasopharyngeal Carcinoma | Nasopharyngeal Neoplasms | Epstein-Barr Virus Infections | Epstein-Barr Viraemia | Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

United States
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Recruiting

Resistance Plus Aerobic Training Using Different Weekly Frequencies And Hypertension (RADAH)

Cardiovascular Diseases | Hypertension | Cardiovascular Risk Factor

Brazil
Nantes University Hospital

Unknown

Cell Bank of Epstein Barr Virus Specific Cytotoxic T Lymphocytes

EBV Associated Lymphoma

France
Children's National Research Institute

Active, not recruiting

Research Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of Solid Tumors (REST)

Solid Tumors

United States
Tianjin Medical University Cancer Institute and...

Unknown

Study of Autologous Cytotoxic T Lymphocyte Immunotherapy Combination With PD-1 Inhibitor in the Advanced NSCLC

Non-small Cell Lung Cancer | Second-line Treatment

China
Xuzhou Medical University

Unknown

DC1s-CTL Cellular Therapy for Renal Cell Carcinoma

Renal Cell Carcinoma
Catherine Bollard

Active, not recruiting

Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)

CMV | EBV | Adenovirus

United States
Atara Biotherapeutics
Memorial Sloan Kettering Cancer Center

Completed

Therapeutic Effects of Epstein-Barr Virus Immune T-Lymphocytes Derived From a Normal HLA-Compatible Or Partially-Matched Third-Party Donor in the Treatment of EBV Lymphoproliferative Disorders and EBV-Associated Malignancies

EBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk for Developing a Recurrent EBV Lymphoma

United States
VA Office of Research and Development

Recruiting

Walking Exercise Sustainability Through Telehealth for Veterans With Lower-limb Amputation (WEST)

Lower-Limb Amputation

United States
CatalYm GmbH

Recruiting

First-in-Human Study of the GDF-15 Neutralizing Antibody Visugromab (CTL-002) in Patients With Advanced Cancer (GDFATHER) (GDFATHER)

Solid Tumor, Adult

Spain, Germany, Switzerland
Gary Doolittle

Completed

Vaccine Enriched, Autologous, Activated T-Cells Directed to Tumor in Patients With Relapsed/Refractory Melanoma (MARVSmALo)

Melanoma

United States
University of Southern California

Completed

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

Substance Use | Alcohol Use, Underage | Alcohol Problem Drinking

United States
Nantes University Hospital

Recruiting

Trial to Assess the Safety and Feasibility of Adoptive Cell Therapy With Autologous EBV-specific Cytotoxic T Lymphocytes (CTL) in Patients With a First Clinical Episode Highly Suggestive of Multiple Sclerosis (MS and EBV-CTL)

Multiple Sclerosis

France
Shenzhen Geno-Immune Medical Institute
Shenzhen Children's Hospital; Shenzhen Hospital of Southern Medical University

Unknown

Immunotherapy Based on Antigen-specific Immune Effector Cells Targeting Neurofibromatosis or Schwannomatosis

Cancer

China
Shenzhen University General Hospital

Recruiting

Treatment of Malignant Tumors With Antigen Peptide-specific DC-CTL Cells and Decitabine

Malignant Tumor

China
National Institute of Diabetes and Digestive and...

Completed

Detection and Cytotoxic T Lymphocyte Therapy of Post-Transplant Lymphoproliferative Disorder After Liver Transplant

Lymphoproliferative Disorders | Liver Disease

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Terminated

Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme (COGLI)

Brain Cancer | Glioblastoma Multiforme | GBM

United States
University College, London
bluebird bio

Active, not recruiting

Immunotherapy With Tacrolimus Resistant EBV CTL for Lymphoproliferative Disease After Solid Organ Transplant (ITREC)

Post-transplant Lymphoproliferative Disease | Transplant-Related Hematologic Malignancy

United Kingdom
Otsuka Pharmaceutical Development & Commercialization...

Terminated

A Phase 1 Study to Investigate the Safety, Tolerance, Food Effect, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of Extended Release Formulations of Centanafadine (CTN) in Young Healthy Subjects

Adult Attention-deficit Hyperactivity Disorder (ADHD)

Australia
Ming Kuang

Unknown

RFA+Highly-purified CTL vs. RFA Alone for Recurrent HCC

Hepatocellular Carcinoma

China
National Institute of Allergy and Infectious Diseases...

Completed

Study of an HIV Preventive Vaccine Given With or Without an Adjuvant in HIV Uninfected Adults

HIV Infections

United States, Thailand
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Vaccine in Adults With HIV

HIV Infections

United States
Shenzhen Geno-Immune Medical Institute

Recruiting

NGS-MRD Assessment of Combination Immunotherapies Targeting B-ALL

B-Cell Acute Lymphoblastic Leukemia

China
Medical University of South Carolina
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Behavioral Stress Reduction Programs on Blood Pressure in African American Youth

Heart Diseases | Cardiovascular Diseases | Hypertension

United States
William Beaumont Hospitals

Recruiting

BTL Emsella Chair Versus Sham for the Treatment of Stress Urinary Incontinence

Stress Urinary Incontinence

United States
Caliway Biopharmaceuticals Co., Ltd.

Completed

A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With EFP; Cellulite (Stage 1)

Cellulite

United States
BTL Industries Ltd.

Completed

BTL-9000 Low Level Laser Therapy for the Waist Circumferential Reduction

Circumferential Reduction | Waist Circumferential Reduction

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