Search clinical trials for: extended release metformin

Total 8287 results

LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone

Healthy

Korea, Republic of
LG Life Sciences

Unknown

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 2000mg in Comparison to Each Component Administered Alone

Healthy

Korea, Republic of
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 500mg in Comparison to Each Component Administered Alone

Healthy

Korea, Republic of
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
National Cancer Institute (NCI)

Recruiting

Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

Lung Carcinoma

United States, Canada
GlaxoSmithKline

Terminated

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers

Diabetes Mellitus, Type 2

Australia
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.

Healthy

Korea, Republic of
University of Hawaii
National Institute of General Medical Sciences (NIGMS)

Unknown

Metformin for HIV Inflammation

Coronary Artery Disease | HIV

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Metformin and Nightly Fasting in Women With Early Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Breast Ductal Carcinoma In Situ | Invasive Breast Carcinoma

United States, Italy
Matthew Neal MD
Berry Consultants; University of Pittsburgh Medical Center

Completed

REMAP Trial for Optimizing Surgical Outcomes at UPMC (UPMCREMAP)

Aging

United States
Woman's
Pfizer; American Cancer Society, Inc.; Our Lady of the Lake Regional Medical...

Withdrawn

Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer (METBC)

Insulin Resistance | Breast Cancer Stage | Racial Bias

United States
Gwendolyn Sowa

Completed

Effects of Metformin on Low Back Pain

Low Back Pain

United States
James Wang
United States Department of Defense

Recruiting

Managing Chronic Tendon Pain by Metformin

Chronic Pain | Tendinopathy | Achilles Tendinopathy

United States
Laboratorios Silanes S.A. de C.V.

Completed

Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)

Healthy

Mexico
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Columbia University
Boston University; Johns Hopkins University; University of California, Berkeley; University of Miami and other collaborators

Recruiting

Metformin in Alzheimer's Dementia Prevention (MAP)

Mild Cognitive Impairment

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin HCl 750 mg XR Under Fasting Conditions

Healthy

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin HCl 750 mg XR Tablets Under Non Fasting Conditions

Healthy

United States
LG Chem

Completed

BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone

Healthy Male Volunteers

Korea, Republic of
Weill Medical College of Cornell University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Trial of an Intervention to Improve Metformin Persistence and Adherence (TreatMet)

Tolerance | Metformin Adverse Reaction

United States
Era's Lucknow Medical College

Completed

Metformin in Overweight Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus

India
Indiana Hemophilia &Thrombosis Center, Inc.

Active, not recruiting

Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency

Plasminogen Activator Inhibitor-1 Deficiency | Cardiac Fibrosis

United States
Duke University

Terminated

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) (NAFLD)

Fatty Liver

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
NYU Langone Health

Completed

Metformin Prostate Cancer Adjuvant Trial

Prostate Cancer | Prostate Cancer Recurrent

United States
AstraZeneca

Recruiting

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

China
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Hangzhou Highlightll Pharmaceutical Co., Ltd

Completed

Evaluation of TLL-018 Extended and Immediate Release Formulation for Bioequivalence Testing in Healthy Chinese Subjects

Atopic Dermatitis

China
Luye Pharma Group Ltd.
Shandong Luye Pharmaceutical Co., Ltd.

Completed

Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LY03005 Extended-release Tablets in the Treatment of Major Depressive Disorder (MDD)

Major Depressive Disorder

China
AstraZeneca

Withdrawn

A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects

Healthy Male Subjects | Pharmacokinetics | Safety | Food Effect

United Kingdom
UConn Health

Completed

Vaccination Efficacy With Metformin in Older Adults (VEME)

Aging | Vaccine Response Impaired | Age-Related Immunodeficiency

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Activity and Metformin Intervention in Obese Adolescents (REACH)

Obesity | Type 2 Diabetes

Canada
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance

Metabolic Syndrome | Insulin Resistance | Type 2 Diabetes

United States
Brigham and Women's Hospital
Arthritis Foundation

Recruiting

Preventing Injured Knees From osteoArthritis: Severity Outcomes (PIKASO)

Osteoarthritis, Knee | Post-traumatic Osteoarthritis | ACL Tear

United States
Ultragenyx Pharmaceutical Inc

Completed

Safety and Pharmacokinetics of Sialic Acid Tables in Patients With Hereditary Inclusion Body Myopathy (HIBM)

Hereditary Inclusion Body Myopathy (HIBM)

United States
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition

Fasting

India
AstraZeneca

Completed

Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil

Type 2 Diabetes Mellitus

Brazil
West Side Institute for Science and Education

Completed

Tolerance & Responsiveness Improvement for Metformin (TRIM)

Type2 Diabetes Mellitus

United States
Laboratorios Silanes S.A. de C.V.
Instituto Mexicano del Seguro Social

Completed

BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study (GLMT13)

Healthy

Mexico
Murdoch Childrens Research Institute

Recruiting

Minimising Adverse Drug Reactions and Verifying Economic Legitimacy in Children (MARVEL-PIC) (MARVEL-PIC)

Neoplasms | Bone Marrow Transplantation

Australia
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fed Condition

Fasting

India
Luye Pharma Group Ltd.

Completed

A Study to Evaluate the Efficacy and Safety of Ansofaxine Hydrochloride Extended-release Tablets in the Treatment of Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

China
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Metformin HCL 500 mg Extended Release (XR) Tablets Under Fasting Conditions

Type II Diabetes
Ultragenyx Pharmaceutical Inc

Terminated

A Study to Evaluate the Safety of Aceneuramic Acid Extended Release (Ace-ER; UX001) Tablets in Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy (GNEM) (Also Known as Hereditary Inclusion Body Myopathy [HIBM]) Patients With Severe Ambulatory Impairment

Hereditary Inclusion Body Myopathy | GNE Myopathy | Inclusion Body Myopathy 2 | Distal Myopathy With Rimmed Vacuoles | Distal Myopathy, Nonaka Type | Quadriceps Sparing Myopathy

Canada, United States, Bulgaria
University of California, Los Angeles

Not yet recruiting

Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo

Obesity | NIDDM

United States
Laboratorios Silanes S.A. de C.V.
Instituto Mexicano del Seguro Social

Completed

BIOAVAILABILITY OF GLI/METXR (4/850 mg) (GLMT12-SIL)

Healthy

Mexico
Dexa Medica Group

Completed

Bioequivalence Study of Two Formulations of 500 mg Metformin Extended Release Tablet

Metformin XR BE Study in Healthy Volunteers With Single and Multiple Dose

Indonesia

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