Search clinical trials for: ezetimibe

Total 398 results

Organon and Co

Completed

Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED)

Coronary Disease | Hypercholesterolemia | Atherosclerotic Disease
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2 (GAUSS-2)

Hyperlipidemia

United States, Denmark, Belgium, Germany, Hong Kong, Netherlands, France, Australia, Canada, South Africa, United Kingdom, Spain, Poland, Switzerland
Texas A&M University
Nutrabolt

Completed

Safety of Different Forms of Creatine (NB9)

Nutritional Supplements
Pfizer

Terminated

A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin (PROSE)

Pulmonary Arterial Hypertension

Belgium, Germany, France
Kiyuk Chang, MD,PhD

Recruiting

Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI (ROSUZET-AMI)

Myocardial Infarction | Statin Adverse Reaction | HMG-CoA Reductase Inhibitor Toxicity

Korea, Republic of
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Withdrawn

Treatment With Bempedoic Acid And/Or Its Fixed-dose Combination With Ezetimibe in Routine Clinical Practice in Patients With Primary Hypercholesterolemia Or Mixed Dyslipidemia (MILOS-Spain)

Mixed Dyslipidemia | Primary Hypercholesterolemia
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With Atorvastatin

Dyslipidemias | Dyslipidaemias

United States
Organon and Co

Completed

A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)

Hypercholesterolemia
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe on Top of Statin in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY COMBO II)

Hypercholesterolemia

United States, Canada, Denmark, France, Hungary, Israel, Korea, Republic of, Russian Federation, South Africa, Ukraine
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Recruiting

Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia (MILOS)

Hypercholesterolemia | Mixed Dyslipidemia

Austria, United Kingdom, Italy, Germany, Belgium
Laboratorios Silanes S.A. de C.V.

Completed

Study to Evaluate the Safety of the Fixed-dose Combination Rosuvastatin/Ezetimibe for Patients With Dyslipidaemia (TREZETE)

Dyslipidemias

Mexico
Ziauddin Hospital

Unknown

Ezetimibe for Patients With Chronic Hepatitis D

Chronic Hepatitis D

Pakistan
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Effectiveness, and Tolerability of Ezetimibe Combined With Statins for the Treatment of High Cholesterol in HIV Infected Adults

HIV Infections

United States, Puerto Rico
Canadian Collaborative Research Network
Schering-Plough

Completed

Effects of Ezetimibe Add-On to Statin Therapy on Adipokine Production in Obese and Metabolic Syndrome Patients With Atherosclerosis

Coronary Artery Disease | Obesity | Metabolic Syndrome

Canada
Pfizer

Completed

Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects

Healthy

United States
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Organon and Co

Completed

Effect of Ezetimibe Treatment on Low-density Lipoprotein Cholesterol (LDL-C) Levels in Participants With Coronary Heart Disease (CHD) Already Treated With a Statin (MK-0653A-205 AM1) (ACT II)

Hypercholesterolemia
Korea University Anam Hospital

Recruiting

A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke

Dyslipidemias | Stroke, Acute Ischemic

Korea, Republic of
Seoul National University Bundang Hospital
Yuhan Corporation

Completed

Efficacy and Safety of Combination Therapy of Moderate-intensity Statin and Ezetimibe Compared to High-intensity Statin

Cardiovascular Diseases

Korea, Republic of
Organon and Co
Merck Sharp & Dohme LLC

Terminated

Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)

Coronary Artery Disease | Atherosclerosis | Hypercholesterolemia
Jordan Feld
University Health Network, Toronto

Recruiting

Transplantation Using Hepatitis C Positive Donors, A Safety Trial

Hepatitis C | Kidney Transplant Infection | Heart Transplant Infection | Lung Transplant Infection | Kidney Pancreas Infection

Canada
Organon and Co

Completed

Efficacy and Safety Study of Ezetimibe (SCH 58235, MK-0653) in Addition to Atorvastatin in Participants With Coronary Heart Disease or Multiple Cardiovascular Risk Factors (P00693/MK-0653-030)

Hypercholesterolemia
Organon and Co

Completed

Eze/Simva Switch Study in Diabetics (0653A-807)

Diabetes Mellitus, Type 2
Organon and Co

Terminated

Vytorin Treating Uncontrolled Lipids (VyTUL) Study (0653A-122)

Cardiovascular Diseases | Diabetes Mellitus
Organon and Co
Merck Sharp & Dohme LLC

Completed

Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)

Hypercholesterolemia
Aegerion Pharmaceuticals, Inc.

Completed

Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS

Hyperlipidemia

United States
Richard E. Ostlund Jr., MD
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Physiological Study of Human Cholesterol Metabolism and Excretion

Cardiovascular Disease | Dyslipidemia | Coronary Heart Disease | Disorder of Cholesterol Metabolism

United States
Pontificia Universidad Catolica de Chile

Unknown

Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection in Liver Transplant Candidates (EZE-2) (EZE-2)

Hepatitis C

Chile
University of California, San Diego

Completed

Effect of Ezetimibe on Flow-mediated Brachial Artery Reactivity in Healthy Subjects

Endothelial Dysfunction
University Medical Centre Ljubljana

Completed

The Impact of Ezetimibe on Biochemical Markers of Cardiovascular Risk in Kidney Transplant Patients

Dyslipidemia | Transplants

Slovenia
Yokohama City University Medical Center

Unknown

The Effects of Ezetimibe on Coronary Plaque Volume in Patients With Acute Coronary Syndrome

Coronary Artery Disease

Japan
Yonsei University

Not yet recruiting

Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial)

Peripheral Artery Disease | Polyvascular Disease

Korea, Republic of
Saint Vincent's Hospital, Korea

Recruiting

Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention (ALMIGHTY)

Coronary Artery Disease | Dyslipidemias | Primary Prevention

Korea, Republic of
NYU Langone Health

Completed

CHOlesterol Lowering and Residual Risk in Type 2 Diabetes (CHORD)

Type 2 Diabetes

United States
Organon and Co

Completed

A Study Comparing Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Patients at Risk for Heart Disease (0653-023)(COMPLETED)

Coronary Disease
University of Sao Paulo

Completed

Antiplatelet and Anti-inflammatory Effects of Statins and Ezetimibe

Stable Angina

Brazil
Organon and Co

Completed

A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)

Type 2 Diabetes Mellitus | Hypercholesterolemia
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study to Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH

Homozygous Familial Hypercholesterolemia

China
Organon and Co

Completed

Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)

Primary Hypercholesterolemia | Homozygous Familial Hypercholesterolemia
Pontificia Universidad Catolica de Chile

Unknown

Pilot Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection (EZE-1)

Chronic Hepatitis C

Chile
University of Palermo

Unknown

Lifestyle Versus Ezetimibe Plus Lifestyle in Patients With Non-alcoholic Steatohepatitis

•Non-alcoholic Steatohepatitis (NASH)

Italy
Organon and Co
Schering-Plough

Completed

MD Ezetimibe Cyclosporine Interaction (0653-057)

Cholesterol
Merck Sharp & Dohme LLC

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of MK-0616 Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018)

Hypercholesterolemia
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Daiichi Sankyo Germany

Completed

SurveY Followed by a Retrospective Chart Review to Describe the Key Factors Leading to Physician's Decision to Treat Patients at High and Very High Cardiovascular Risk With hyperchOlesterolemia or Mixed Dyslipidemia With NUSTENDI®

Hypercholesterolemia | Mixed Dyslipidemia

Germany
Keun-Sik Hong
Samsung Medical Center; Seoul St. Mary's Hospital; Seoul National University... and other collaborators

Unknown

Study on Rosuvastatin+Ezetimibe and Rosuvastatin for LDL-C Goal in Patients With Recent Ischemic Stroke

Stroke, Ischemic

Korea, Republic of
Organon and Co
Merck Sharp & Dohme LLC

Completed

Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476)

Atherosclerosis | Hypercholesterolemia | Coronary Heart Disease
Policlinico Casilino ASL RMB
IRCCS San Raffaele

Unknown

Evolocumab Plus Ezetimibe in Haemodialized Statin-intolerant Patients With Hypercholesterolemia

Hypercholesterolemia | CKD Stage 5 | Chronic Kidney Disease Requiring Chronic Dialysis

Italy
Organon and Co

Completed

A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173)

Primary Hypercholesterolemia
University of Manitoba

Completed

Sitosterolemia Metabolism (STAIR7002)

Sitosterolemia

Canada
University of California, San Diego

Completed

Ezetimibe Versus Placebo in the Treatment of Non-alcoholic Steatohepatitis

Non Alcoholic Steatohepatitis

United States

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